Clinical trials: Tooth Bleaching
Tooth Hypersensitivity
Hypersensitivity and Color Changes of Bleached Teeth Using Different Remineralizing Agents
The aim of this in vivo study is to evaluate the post-bleaching enamel hypersensitivity and the possible color changes following the application of arginine and nano-hydroxyapatite remineralizing solutions after enamel bleaching…
- Trial name
- NCT04875000
- Testing
- Remineralizing agent I application, Remineralizing agent II application, Remineralizing agent III application
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Dental Devices, Home Care
Two Week Cumulative Extrinsic Stain Removal of a Battery-powered Toothbrush and a Manual Toothbrush
To evaluate and compare the extrinsic stain removal efficacy of a battery-powered toothbrush and a manual toothbrush following two weeks of brushing.
- Trial name
- NCT06292611
- Testing
- Battery operated toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Dentin Sensitivity, Tooth Bleaching
Evaluation of Sensitivity With and Without Sonic Activation of a Desensitizing Gel Before in Office Bleaching in Adults
This randomized, controlled clinical trial, triple-blind, split-mouth type was conducted aiming to assess the absolute risk of sensitivity with and without sonic activation of a desensitizing gel previously to the in-office…
- Trial name
- NCT03039270
- Testing
- With sonic activation (SMART Device®), Control (Without sonic activation)
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Federal University of Amazonas
Tooth Whitening, Tooth Discoloration
Clinical Research Study to Evaluate Stain Removal and Whitening Improvement
The objective of this clinical research study is to evaluate the stain removal and whitening improvement of a toothpaste containing Vitamin C and 1100 ppm F as sodium fluoride as compared to a matching placebo toothpaste…
- Trial name
- NCT07870018
- Testing
- Vitamin C toothpaste
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Bleaching; Satisfactory, Bleaching Sensitivity
Effect of Bleaching Regimen With Different Activation Modes on Color Stability, Surface Roughness, Tooth Sensitivity and Patient Satisfaction
The purpose of this study was to conduct a randomized double-blind clinical trial to examine the efficacy of an in-office bleaching regimen with varied activation modes on color stability, surface roughness, tooth sensitivity…
- Conditions
- Bleaching; Satisfactory, Bleaching Sensitivity, Bleaching Efficacy
- Trial name
- NCT07493941
- Testing
- 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with Laser Activation, 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with LED/Light Activation, 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) - Chemical Activation Only
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tanta University
Dental Fluorosis
Clinical Evaluation of Dental Fluororsis Treatment Modalities
Background: Various treatment modalities are available to improve esthetics of fluorosed teeth based on its severity. Aim: evaluate the clinical performance of different minimal invasive treatment protocols on mild to moderate…
- Trial name
- NCT05204277
- Testing
- Opalescence™ boost™ PF 40%, Opalustre™, MI-Paste Plus®
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Medicaments Substances in Therapeutic Use
Potassium Oxalate and Potassium Nitrate and Post-bleaching Sensitivity
Objectives: This study will determine the effectiveness of the use of desensitivity gels prior in office bleaching on risk and intensity of tooth sensitivity caused by in-office bleaching using 35% hydrogen peroxide.
- Trial name
- NCT02941653
- Testing
- Potassium nitrate 2% gel, Potassium oxalate 5% gel
- Where
- Brazil
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Gingival Inflammation
Gingival Irritation Due to Bleaching Tray Design in an At-home Bleaching Treatment
The primary aim of this study is to assess whether the design of the bleaching tray used in at-home bleaching treatment is directly correlated with the risk of gingival irritation.
- Trial name
- NCT06371664
- Testing
- Conventional Tray (1 mm), Extended Tray (3 mm)
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Dentin Sensitivity, Oral Hygiene
A Study Assessing the Effects of an Experimental Dentifrice in Maintaining Tooth Color Following Tooth Bleaching
The main aim of this study is to investigate the ability of an experimental dentifrice containing 5 percent (%) potassium nitrate (KNO3), 1% alumina and 5% sodium tripolyphosphate (STP), to maintain tooth color and reduce…
- Trial name
- NCT06150573
- Testing
- Test Dentifrice, Reference Dentifrice (Aquafresh Cavity Protection)
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Sensitivity
A Clinical Study Assessing the Effects of a Marketed Dentifrice on Tooth Sensitivity While Undergoing Tooth Bleaching
The aim of this study is to investigate the efficacy of a marketed dentifrice containing 5 percent (%) NovaMin (Calcium Sodium Phosphosilicate) to reduce tooth sensitivity during and post tooth bleaching compared to a marketed…
- Trial name
- NCT06608368
- Testing
- Test Dentifrice (Sensodyne Repair and Protect Original Mint), Positive Control Dentifrice (Sensodyne Fresh Mint), Reference Dentifrice (Crest Cavity Protection Regular)
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- HALEON
Dental Hypersensitivity, Teeth Whitening
Effectiveness of 16% Carbamide Peroxide in Reducing Hypersensitivity During Alternate-day Home Bleaching
The concentration of 16% carbamide peroxide is the highest concentration that European regulations allow for use in home whitening (Council directive 2011/84/EU).
- Trial name
- NCT06035588
- Testing
- Daily whitening, Alternate whitening
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Tooth Discoloration, Quality of Life
Influence of Tooth Whitening on Changes in Quality of Life
Lighter tooth color may improve patient satisfaction with facial aesthetics. Few data exist regarding the impact and association of of tooth color connection with quality of life.The purpose of this research is to explore the…
- Trial name
- NCT03380702
- Testing
- whitening photoactivation gel
- Where
- Croatia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Daniela Kovacevic Pavicic
Tooth Discoloration
Efficacy of Laser Application in Dental Bleaching
Objective: To establish the efficacy of laser application with chemical treatment in dental bleaching compared to chemical treatment alone.
- Trial name
- NCT03688893
- Testing
- Laser Application for Dental Bleaching
- Where
- Paraguay
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Caaguazu
Whitening
Clinical Study to Evaluate the Tooth Whitening Efficacy
Optic White 5%HP ActivShine TP vs Crest3D White TP (head-to-head whitening clinical) The objective of this study is to evaluate the tooth whitening efficacy of a Colgate toothpaste with 5% Hydrogen Peroxide and Fluoride compared…
- Trial name
- NCT06957249
- Testing
- Optic White 5%HP ActivShine Toothpaste, Crest3DWhite Advanced Radiant Mint Toothpaste
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Discolored Teeth
In-office and At-home Tooth Bleaching Using Low Concentration Peroxides.
To evaluate the efficacy, safety and impact on quality of life related to oral health of home and office tooth whitening techniques in young individuals.
- Trial name
- NCT02816593
- Testing
- hydrogen peroxide 6%, hydrogen peroxide 15%, Carbamide Peroxide 10%
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Teeth Color, Teeth Staining
A Clinical Study to Evaluate the Stain Reduction Efficacy of a Non-Fluoride Tooth Whitening Dentifrice Containing Nano-Hydroxyapatite (nHAP) and a High Cleaning Silica Abrasive System Compared to a Commercial Fluoride Non-Whitening Dentifrice as a Negative Control
To determine whether brushing with a non-fluoride tooth whitening dentifrice containing nHAP and a high cleaning silica system produces a greater level of stain reduction as indicated by the Modified Lobene Stain Index (MLSI) for…
- Trial name
- NCT07214038
- Testing
- toothpaste
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Boka LLC
Tooth Discoloration, Tooth Staining
Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized Nightguards
This randomized, double-blind, split-mouth clinical trial evaluates the effectiveness of at-home dental bleaching using customized nightguards fabricated by digital (3D-printed CAD-CAM) and conventional methods, with and without…
- Trial name
- NCT07464197
- Testing
- Customized bleaching tray fabrication, Reservoir tray design, Carbamide peroxide 10%
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Tooth Bleaching
Clinical Evaluation for Post Bleaching Hypersensitivity Using Desensitizing Agent During In-office Bleaching
Evaluating the effect of a desensitizing agent on post-bleaching hypersensitivity.
- Trial name
- NCT02942082
- Testing
- ACP oral care gel, glycrin
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Discoloration, Color Changes During Tooth Formation
Office Bleaching Treatment by Using Rubber-cup and Air-powder Polishing Device Prophylaxis in Rondomised Clinical Design
The increasing demand for whitening teeth necessitates requirements and guidelines to ensure the efficacy of products and bleaching techniques.
- Trial name
- NCT04407910
- Testing
- AIRFLOW® Master device +Opalescence Xtra Boost., rubber-cup+Opalescence Xtra Boost.
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Tooth Bleaching
Effect of Gel Renewal During In-office Dental Bleaching
Considering the lack of studies related to the violet LED light (405-410nm), applied to tooth whitening, as well as the lack of protocols for its use, this study aims to evaluate if bleaching gel renewal during dental office…
- Trial name
- NCT04013659
- Testing
- Dental Bleaching with 35% hydrogen peroxide gel + Violet LED Irradiation
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universidade Ibirapuera