Clinical trials: Tonsillitis
IgA Nephropathy
Effect of Tonsillectomy on Longterm Renal Outcome of IgA Nephropathy
The effect of tonsillectomy therapy on IgA nephropathy is still controversial.Few prospective,randomized investigations have examined how tonsillectomy affects the shortterm and longterm renal outcome of IgA nephropathy.This is A…
- Trial name
- NCT02471599
- Testing
- tonsillectomy, non-tonsillectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Chronic Tonsillitis
Evaluation of Coblation Channeling Treatment for Chronic Tonsillitis.
To evaluate coblation channeling treatment for chronic tonsillitis. Does Tonsillar ablation can create changing in the tonsillar medium for recurrent tonsillar infections and stop the recurrent infections?
- Trial name
- NCT02981810
- Testing
- Arthrocare® Corporation (ArthroCare Corporation, 7500 Rialto Boulevard Austin, Texas 78735) COBLATION electrode ReFlex Ultra 55*, tonsillectomy
- Volunteers
- 120 people
- Sponsor
- Hillel Yaffe Medical Center
Tonsillitis Recurrent
Tonsillectomy Versus Tonsillotomy in the Treatment of Recurrent Acute Tonsillitis
Background: recurrent acute tonsillitis (RT) is a frequent condition affecting teenagers and adults. Patients suffer from recurring throat symptoms, fever and impaired quality of life (QOL).
- Trial name
- NCT06606262
- Testing
- Tonsillotomy, Tonsillectomy
- Where
- 2 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- Tejs Ehlers Klug
Adenotonsillar Hypertrophy, Tonsillitis
Comparison of Floseal Hemostasis Tonsillectomy With Coblation Tonsillectomy and Cautery Hemostasis Tonsillectomy
The purpose of this study is to evaluate a new method of hemostasis, floseal gel, in tonsillectomy and adenoidectomy, with the goal of decreasing post operative and intraoperative morbidity.
- Conditions
- Adenotonsillar Hypertrophy, Tonsillitis, Obstructive Sleep Apnea
- Trial name
- NCT00459927
- Testing
- Floseal tonsillectomy, Coblation tonsillectomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Sore Throat, Tonsillitis
Sore Throat in Primary Care - a Comparison of Phenoxymethylpenicillin and No Antibiotic Treatment
Sore throat is the second most common cause of antibiotic prescribing in primary care in Sweden. Guidelines for sore throat focus on identifying people with sore throat where there are 3 and 4 specified criteria and where near…
- Trial name
- SANT (NCT04083417)
- Testing
- Phenoxymethylpenicillin, No antibiotic treatment
- Where
- 6 sites in Sweden
- Volunteers
- 260 people
- Sponsor
- Katarina Hedin
Respiratory Tract Infections
Procalcitonin Guided Antibiotic Use in Acute Respiratory Tract Infections (PARTI)-Study
Acute respiratory tract infections (ARTI) are among the most frequent reasons for seeking medical attention in primary care. Although from predominantly viral origin, ARTIs are the most important condition for the prescription of…
- Trial name
- NCT00099840
- Testing
- Procalcitonin guided antibiotic therapy
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Basel, Switzerland
Tonsil Disease, Tonsillitis
Intracapsular Tonsillectomy in Adults
Comparing the classical extracapsular tonsillectomy (TE) performed with electrosurgery to intracapsular approaches (SIPT) by coblation or microdebrider. The patient group is adults with recurrent or chronic tonsillitis
- Conditions
- Tonsil Disease, Tonsillitis, Tonsillitis Acute, Tonsillitis Chronic
- Trial name
- NCT03654742
- Testing
- tonsillectomy
- Where
- Finland
- Volunteers
- 167 people
- Sponsor
- Turku University Hospital
Tonsillectomy, Tonsillitis Chronic
BiZact Tonsillectomy in the Pediatric Population
This study has been designed to evaluate how effective the Bizact tonsillectomy device is in reducing operating time and complications that occur after surgery.
- Conditions
- Tonsillectomy, Tonsillitis Chronic, Hemorrhage, Postoperative Pain
- Trial name
- NCT04725305
- Testing
- BiZact, Standard of care
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Baylor College of Medicine
Sore Throat, Pharyngitis
APC-111 MP Tablet Once a Day vs.Penicillin VK Four Times a Day Both for 10 Days in Patients With Strep Throat
The primary objective of this study is to evaluate the efficacy of APC 111 MP Tablet, 775 mg tablet, given orally (PO)once daily (QD) for 10 days compared to that of Penicillin VK, 250 mg PO four times daily (QID) for 10 days in…
- Conditions
- Sore Throat, Pharyngitis, Tonsillitis
- Trial name
- NCT00242281
- Testing
- APC-111 MP Tablet, 775 mg
- Where
- 41 sites in United States, Canada
- Volunteers
- 600 people
- Sponsor
- Advancis Pharmaceutical Corporation
Chronic Tonsillitis
Study Comparing Harmonic Scalpel and Conventional Cold Steel Tonsil Removal Surgery in Children Requiring Tonsillectomy
This clinical trial aims to compare two commonly used methods of tonsil removal surgery (tonsillectomy) in children and adults with chronic tonsillitis.
- Trial name
- NCT07656831
- Testing
- Cold Steel Dissection Tonsillectomy, Harmonic Scalpel Tonsillectomy
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Allama Iqbal Teaching Hospital
Pharyngitis, Tonsillitis
A Multicenter, Randomized, Double-Blind, Double-Dummy Comparative Trial of Azithromycin Sustained Release Versus 3-Day Azithromycin for the Treatment of Strep Throat in Adolescents and Adults
To determine if a single 2.0-g dose of azithromycin SR is at least as effective as a 3-day course of azithromycin (500 mg once daily for 3 days) when used to treat adolescents and adults with strep throat, and to assess efficacy…
- Trial name
- NCT00644293
- Testing
- azithromycin (Zithromax), azithromycin SR
- Where
- 59 sites in United States, Belgium and 8 more
- Volunteers
- 598 people
- Sponsor
- Pfizer
Tonsillitis, Tonsillectomy
Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy
The purpose of this pilot study: 1) to examine the use of gabapentin in reducing pain in the first 48 hours postoperatively including the total amount of narcotics mg/kg given 2) to record the time to first analgesic…
- Trial name
- NCT03625011
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Tonsillitis
Vitamin D Levels in Children Undergoing Adenotonsillectomies and Controls
The investigators aim to evaluate the levels of serum Vitamin D in children having their tonsils removed and appropriate controls.
- Trial name
- NCT00829972
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Chicago
Acute Tonsillitis
Registration of the Study of Reyanning Mixture
The purpose of this study is to evaluate the efficacy and safety of treating with acute tonsillitis using Reyanning mixture alone/in combination with antibiotics, and its function of reducing the use of antibiotics.
- Trial name
- NCT03704506
- Testing
- Reyanning mixture, amoxil capsule, Reyanning mixture simulator
- Volunteers
- 144 people
- Sponsor
- China Academy of Chinese Medical Sciences
Apnea, Obstructive, Tonsillitis
Evaluation of the Functional Impact of Adenotonsilectomy
Spirometric assessment of respiratory function before and after adenotonsillectomy surgery
- Conditions
- Apnea, Obstructive, Tonsillitis, Tonsillar Hypertrophy, Respiratory Function Impaired
- Trial name
- NCT05532228
- Testing
- Adenotonsillectomy
- Where
- Portugal
- Volunteers
- 78 people
- Sponsor
- Instituto de Ciências Biomédicas Abel Salazar
Pharyngitis, Tonsillitis
APC-111 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) for 10 Days in Patients With Strep Throat
The purpose of the this study is to evaluate the safety of efficacy of APC-111 775 mg MP tablet once daily dosing for 7 days for treating patients with strep throat.
- Trial name
- NCT00095368
- Testing
- Amoxicillin Pulsatile Release Multiparticulate Tablet (drug)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Advancis Pharmaceutical Corporation
Anesthesia, Opioid Use
Opioid-Free Anesthetic for Tonsillectomy
Prospective randomized controlled trial to determine if opioid-free anesthetic for tonsillectomy is non-inferior to standard opioid-containing anesthetic
- Conditions
- Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder
- Trial name
- NCT04528173
- Testing
- Ketorolac, Dexmedetomidine, Morphine
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Tonsillitis, Postoperative Pain
Does Ice Cream Help With Post-tonsillectomy Pain
Tonsillectomy is one of the most performed procedures in childhood, which carries with it certain postoperative problems, such as the pain of the operated area.
- Conditions
- Tonsillitis, Postoperative Pain, Cryotherapy Effect
- Trial name
- NCT04164511
- Testing
- 2 daily standard doses of vanilla-chocolate ice cream (cryotherapy)
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- University Hospital Sestre Milosrdnice
Tonsillitis, Streptococcus Pharyngitis
Antimicrobial Stewardship Program (ASP) in Patients With a Sore Throat
The investigators have developed an antibiotic stewardship program (ASP) to increase adherence to the Swedish guidelines for managing patients with a sore throat.
- Conditions
- Tonsillitis, Streptococcus Pharyngitis, Sore Throat, Pharyngitis
- Trial name
- ASP-Throat (NCT03408704)
- Testing
- ASP
- Where
- Sweden
- Volunteers
- 49 people
- Sponsor
- Vastra Gotaland Region
Enlargement of Tonsil or Adenoid
Bioclinical Profile of Adenotonsillar Hypertrophy in the Pediatric Population
Adenotonsillar hypertrophy is the principal cause of obstructive sleep apnea of childhood, yet little is known with regard to its pathophysiologic and molecular mechanisms.
- Trial name
- NCT03541434
- Testing
- Complete Blood Count, Tympanometry, Tonsillectomy and/or adenoidectomy
- Where
- 2 sites in Greece
- Volunteers
- 134 people
- Sponsor
- University of Patras