Clinical trials: Tobacco Smoking
Smoking
Pilot Study: Preoperative Nicotine Lozenges
The goal of this pilot study is to determine the feasibility and potential effect size of nicotine lozenges as an adjunct to maintain brief preoperative abstinence, defined as not smoking the day of surgery.
- Trial name
- NCT00586482
- Testing
- Nicotine Lozenge, Abstinence Advisement
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Mayo Clinic
Acute Coronary Syndrome
Evaluation of Varenicline (Champix) in Smoking Cessation for Patients Post-Acute Coronary Syndrome (EVITA) Trial
The EVITA study is a clinical trial that will test the effect of varenicline (Champix™), a new drug used to help people quit smoking, in patients who have suffered a heart attack.
- Trial name
- EVITA (NCT00794573)
- Testing
- varenicline
- Where
- 4 sites in Canada
- Volunteers
- 302 people
- Sponsor
- Mark Eisenberg
Vaping
Responses to Message Source and Presentation Using Psychophysiology
The goal of this clinical trial is to use psychophysiological methods to test the effects of a message source (expert and peer) and message presentation types (one-sided and two-sided) to identify the optimal message type for…
- Trial name
- NCT06269003
- Testing
- Expert, one-sided, Expert, two-sided, Peer, one-sided
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Tobacco Use Cessation, Alcohol-related Disorders
Concurrent Alcohol and Smoking Treatment: Effects on Alcohol Relapse Risk
The majority of individuals with alcohol problems remain current smokers, and the negative health consequences of smoking among these individuals are substantial.
- Trial name
- NCT00861146
- Testing
- behavioral counseling plus contingency management
- Where
- 2 sites in United States
- Volunteers
- 151 people
- Sponsor
- Yale University
Smoking &Amp; Tobacco Cessation
An Innovative Conversational Agent (Quitbot) for Smoking Cessation
This phase III trial compares two remote digital smoking cessation programs to see how well they work for quitting smoking.
- Trial name
- NCT04308759
- Testing
- Experimental Smoking Cessation Program, Control Smoking Cessation Program
- Where
- United States
- Volunteers
- 1,647 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Tobacco Smoking
Cognitive and Emotional Skills to Aid Smoking Prevention
The purpose of the current proposal is to investigate the extent to which interventions designed to improve cognitive (working memory) and emotional (distress tolerance) regulatory processes enhance the effectiveness of standard…
- Trial name
- DOAN (NCT03058991)
- Testing
- Distress Tolerance Intervention, Working Memory Intervention, Control Informational Intervention
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Smoking Cessation
A Pilot Study Of Smoking Cessation Treatment Including Varenicline In Patients Scheduled For Planned Surgery
It is possible to offer smoking cessation treatment including varenicline to patients scheduled for elective surgery. This study will evaluate whether or not this will enable some patients to quit smoking for up to 4 weeks prior…
- Trial name
- NCT00889720
- Testing
- Varenicline
- Where
- 2 sites in France, Italy
- Volunteers
- 16 people
- Sponsor
- Pfizer
Smoking Cessation
Cigarette Pack Inserts for Smoking Cessation
This study will test whether cigarette package inserts (i.e., small printed leaflets inside cigarette packs) with messages about the benefits of cessation and tips for quitting can help smokers quit.
- Trial name
- NCT04075682
- Testing
- Inserts with efficacy messages, Pictorial warnings on packs
- Where
- 2 sites in United States
- Volunteers
- 387 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Smoking, Cigarette
Tobacco Use Treatment in Cancer Patients
Tobacco use among cancer survivors reduces the effectiveness of cancer treatments, increases the risk for additional primary cancers, and increases mortality.
- Trial name
- NCT03482583
- Testing
- Nicotine Replacement Therapy, Referral to AHEC/Quitline
- Where
- 5 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Florida
Tobacco Use Disorder
Persistence-Targeted Smoking Cessation
The investigators propose to develop a theory-based smoking cessation intervention (called Persistence-targeted smoking cessation; PTSC).
- Trial name
- PTSC (NCT01654107)
- Testing
- Persistence Targeted Smoking Cessation, Clearing The Air, Nicotine lozenge
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Nicotine, Nicotine Vaping
Developing E-liquid Product Standards (Sweet Spot Study)
The Sweet Spot Study aims to evaluate the effect of e-liquids with nicotine varying in freebase (FB) levels and concentrations on the appeal of electronic cigarettes (ECs) in young adult EC users with minimal/no history of…
- Conditions
- Nicotine, Nicotine Vaping, E-cigarette Use
- Trial name
- NCT05864586
- Testing
- Vaping study EC A, Vaping study EC B, Vaping study EC C
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Smoking
The Effect of Naltrexone and Varenicline on Alcohol-Mediated Smoking Lapse
The purpose of this study is to examine how medications thought to attenuate the effects of alcohol (naltrexone) and smoking cessation medications (varenicline) affect the ability to resist smoking and also subsequent ad-lib…
- Trial name
- NCT00773422
- Testing
- naltrexone, varenicline
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Smoking
Behavioral Activation Intervention, Reward Processing, and Youth Smoking Cessation
The primary purpose of this study is to develop a specialized behavioral activation treatment for smoking in youths ages 18-21 with elevated depressive symptoms.
- Trial name
- NCT01351766
- Testing
- Transdermal Nicotine Patch
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Maryland, College Park
Smoking
Bio-Behavioral Predictors of the Efficacy of Nicotine Replacement Therapy (NRT)
The purpose of this research study is to: 1. compare the effectiveness of a nicotine patch and nicotine nasal spray for smoking cessation; and 2.
- Trial name
- NCT00326781
- Testing
- Nicoderm Transdermal Patch, Nicotine Nasal Spray
- Where
- United States
- Volunteers
- 674 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoker
Online Survey in Studying Smoking Attitudes and Behaviors Among Current Smokers
This trial uses an online survey to study smoking attitudes and behaviors among current smokers. An online survey consisting of questions about general demographics, smoking history, smoking attitudes, smoking behaviors, smoking…
- Trial name
- NCT03863795
- Testing
- Survey Administration
- Where
- United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Tobacco Use Cessation, Smoking Cessation
Treating Low-Income Smokers in the Hospital Emergency Department
This study will test the effectiveness of an Emergency Department (ED) initiated tobacco intervention which includes counseling and medication.
- Conditions
- Tobacco Use Cessation, Smoking Cessation, Smoking, Tobacco Use Disorder
- Trial name
- NCT01328431
- Testing
- Brief Intervention with NRT Initiation
- Where
- United States
- Volunteers
- 780 people
- Sponsor
- Yale University
Tobacco Use Disorder
Evaluation of Oral Tobacco as a Harm Reduction Method for Smokers
Recently, tobacco companies have developed new oral tobacco products that are purportedly less harmful than conventional tobacco products.
- Trial name
- NCT00711100
- Testing
- Camel Snus, Marlboro Snus, Stonewall
- Where
- 2 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy Subjects
Pharmacokinetics & Tolerability Study of MAP0004 in Smoking and Non-Smoking Adult Volunteers
Compare the pharmacokinetics of Dihydroergotamine Mesylate (DHE) delivered by oral inhalation (MAP0004) or Intravenous (IV) DHE in smokers versus non-smokers.
- Trial name
- NCT01199965
- Testing
- MAP0004, IV DHE
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Allergan
Smoking Cessation, Smoking, Tobacco
PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness
This is a research study investigating a smoking cessation program tailored for adults with serious mental illness (SMI). The program uses a Videogame-based Physical (VIP) activity, smoking cessation counseling, and medication…
- Conditions
- Smoking Cessation, Smoking, Tobacco, Mental Illness, Tobacco Use Disorder
- Trial name
- PARQuit (NCT03950427)
- Testing
- Videogame-based physical activity, Sedentary videogame, Bupropion
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of California, San Francisco
Hookah Smoking
Optimizing Risk Messages for Waterpipe Tobacco Cessation in Young Adults
The objective of this study is to examine whether messages conveying the harms and addictiveness of waterpipe (i.e., hookah) tobacco delivered by mobile phone multimedia messaging (MMS) are effective for promoting hookah tobacco…
- Trial name
- NCT03595280
- Testing
- Hookah tobacco risk messages
- Where
- 2 sites in United States
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- Georgetown University