Clinical trials: Tobacco Addiction
Nicotine Dependence
Study on Sit to Quit Phone Intervention
This study is designed to test the effectiveness of the smoking cessation intervention "Sit to Quit" through a randomized-control trial.
- Trial name
- NCT02840435
- Testing
- Sit to Quit, Quit for Life
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Duke University
Tobacco Dependence, Smoking Cessation
Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence
The addition of tDCS as an adjunct to pharmacotherapy is a novel approach but one that is grounded in a growing evidence-base.The primary objective of this research is to provide preliminary evidence of the effectiveness of tDCS…
- Conditions
- Tobacco Dependence, Smoking Cessation, Tobacco Smoking, Tobacco Use Disorder
- Trial name
- NCT03841292
- Testing
- Varenicline, Active tDCS
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Centre for Addiction and Mental Health
Smoking (Tobacco) Addiction
Impact of Exercise Associated With Cognitive-behavioral Therapy in Smokers
Smoking remains one of the leading causes of global morbidity and mortality, responsible for more than 8 million deaths annually, according to data from the World Health Organization.
- Trial name
- NCT07186049
- Testing
- Thesis Sessions, General Health Guidelines, Thesis and Exercises
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Agnaldo José Lopes
Smoking Cessation, Smoking Cessation Intervention
Unraveling the Genetic Basis of Nicotine Addiction for Novel Therapeutic Strategies
This case-control study aims to investigate the genetic and molecular bases of nicotine addiction to identify potential therapeutic targets.
- Conditions
- Smoking Cessation, Smoking Cessation Intervention, Nicotine Addiction, Epigenetics
- Trial name
- NicoGen (NCT06471387)
- Testing
- Flexiquit Smoking Cessation Intervention
- Where
- Cyprus
- Volunteers
- 200 people
- Sponsor
- University of Cyprus
Nicotine Addiction
Non-Invasive Deep Brain Neuromodulation for Smoking Cessation
This study will develop novel low intensity focused ultrasound (LIFU) therapy to help people to quit cigarette smoking. Smoking is associated with cancers of the lung. Available smoking cessation methods help many to quit.
- Trial name
- NCT07298902
- Testing
- Low intensity focused ultrasound with active stimulations
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Tobacco Use Disorder
Impact of Cigar Flavor in Dual Users
The purpose of this study is to understand addiction to filtered cigars (FCs) compared to cigarettes in young adults, ages 21-34, who smoke both cigarettes and cigars.
- Trial name
- NCT04487470
- Testing
- Flavored filtered cigars, Unflavored filtered cigars
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- UConn Health
Tobacco Use Disorder
The Effects of Memantine and Bupropion on Acute, Reinforcing, and Conditioned Effects of Cigarettes - 1
One of nicotine's effects on the body is at the level of the NMDA receptors in the brain. Memantine is a drug that also affects NMDA receptors, making it a candidate for the treatment of nicotine addiction.
- Trial name
- NCT00136747
- Testing
- Memantine, bupropion
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Smoking Cessation, Nicotine Addiction
Factors Sustaining Tobacco Abstinence in Cancer Patients Treated With Radio-chemotherapy or Radiotherapy
The TABAC STOP ORL POUMON study aims to evaluate the factors influencing long-term smoking cessation in patients with head and neck cancer (HNC) or lung cancer undergoing radiotherapy or chemoradiotherapy.
- Conditions
- Smoking Cessation, Nicotine Addiction, Nicotine Dependence, Smoking
- Trial name
- TABAC STOP ORL (NCT06910566)
- Testing
- Chemoradiotherapy or radiotherapy alone
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Oscar Lambret
Nicotine Dependence
Repetitive Transcranial Magnetic Stimulation (rTMS) for Nicotine Addiction
Cigarette smoking remains a significant public health concern. A magnetic field applied to the outside of the skull can produce electrical activity in the brain without significant pain or the need for anesthesia.
- Trial name
- rTMS (NCT02401672)
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Nicotine Dependence
Cue Induced Imaging in Nicotine Dependent Smokers
The purpose of this study is to evaluate the relationship between craving to smoke and areas activated in brain. The researchers are using functional magnetic resonance imaging (MRI) that measures brain blood flow, or perfusion…
- Trial name
- NCT00844701
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Smoking (Tobacco) Addiction, Smoking ( Cigarette)
Measuring Communal Coping in Dual-smoking Couples Making a Quit Attempt
Smoking is the leading preventable cause of death in the United States, and quitting is especially difficult for couples who both smoke.
- Conditions
- Smoking (Tobacco) Addiction, Smoking ( Cigarette), Tobacco, Tobacco Abstinence
- Trial name
- NCT07553962
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Colorado, Denver
Smoking Cessation Intervention, Pain
Oklahoma Study of Native American Pain Risk IV: Smoking Cessation and Pain
The goal of this pilot study is to assess whether 4-weeks of verified smoking abstinence following financial incentive treatment for smoking cessation improves physiological markers of chronic pain risk in adult Native American…
- Conditions
- Smoking Cessation Intervention, Pain, Smoking (Tobacco) Addiction
- Trial name
- OK-SNAPIV (NCT07080788)
- Testing
- Smoking Cessation
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Nicotine Addiction, Smoking Cessation
e-Cigarettes Versus NRT Gum for Smoking Cessation
This is a randomized trial comparing electronic cigarettes (e-Cigarettes) to nicotine gum for smoking cessation. Participants will be randomly assigned to either e-cigarette use or nicotine gum use during a quit attempt.
- Trial name
- NCT01925781
- Testing
- Nicotine polacrilex, STAM 1100mAh CE4 eGo Clearomizer
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Creighton University
Asperger's Disorder, Asperger Disorder
QAIAx (AIhealth4U) - AI Smart Health Cities: Microcity Enclave Program (Quantum AI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum AI/AGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Nicotine Dependence
Transcranial Direct Current Stimulation in a Smoking Cessation Trial
The purpose of this study is to determine the effectiveness of transcranial direct current stimulation (tDCS) plus nicotine patch as a viable smoking cessation program for nicotine dependent smokers.
- Trial name
- tDCS (NCT01710410)
- Testing
- active transcranial Direct Current Stimulation
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Drug Addiction
Effect of Varenicline on Tobacco Addiction and on Abstinence-induced Cognitive Impairment
Background: Varenicline (Chantix ) is a drug that is approved by the Food and Drug Administration (FDA) to help people stop smoking.
- Trial name
- NCT01309685
- Testing
- Varenicline
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking Cessation
Impact of a Gene Test for Susceptibility to Lung Cancer in Smokers
Professor RP Young (Associate Professor of Medicine and Molecular Medicine, School of Biological Sciences, University of Auckland) and his team have developed a reliable genetic test "Respiragene" based on 20 single nucleotide…
- Trial name
- NCT01176383
- Testing
- Respiragene test and risk score
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Sussex NHS Research Consortium
Smoking, Tobacco Smoking
Pilot Study of Contingency Management for Smoking Cessation
The purpose of this study is to see whether contingency management (CM) can be successfully added as an adjunct treatment to standard stop smoking services in outpatients undergoing treatment for opiate addiction.
- Conditions
- Smoking, Tobacco Smoking, Smoking, Tobacco, Smoking Cessation
- Trial name
- NCT03015597
- Testing
- Contingency Management
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- King's College London
Tobacco Use Disorder
An fMRI Study of the Effects of Clavulanic Acid on Drug Addiction
This research study is looking into the effects of clavulanic on smoking behavior in adult cigarette smokers. The primary study hypothesis is that, compared to placebo, clavulanic acid will reduce smoking over the course of the…
- Trial name
- NCT03713424
- Testing
- Clavulanic Acid
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Smoking
Treatment to Quit Smoking
This protocol evaluates the efficacy of combining pharmacologic treatments for smoking cessation, entailing the use of the nicotine skin patch with the nicotinic antagonist mecamylamine, with a specific behavioral therapy…
- Trial name
- NCT00018161
- Testing
- Mecamylamine, Nicotine Patch, Cigarette brand switching
- Where
- United States
- Sponsor
- US Department of Veterans Affairs