Clinical trials: Tobacco Abstinence
Schizophrenia, Cigarette Smoking
Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia
This study is designed to evaluate if a treatment the investigators call iCOMMIT is effective at helping smokers with schizophrenia stop smoking.
- Trial name
- NCT02420015
- Testing
- Nicotine replacement therapy, Bupropion, cognitive-behavioral smoking cessation counseling
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Duke University
Tobacco Use Cessation
Quit IT: Development of a Web-based, 3D Coping Skills Game to Increase Self-Efficacy for Maintaining Smoking Abstinence Following Hospitalization
The purpose of this study is to test a web-based video game to help cancer patients quit smoking. The investigators are interested in what participants like and do not like about the game.
- Trial name
- NCT01915836
- Testing
- web-based video game (Quit IT), Questionnaires, Evaluation Interview
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Smoking Cessation, Smoking
NicVAX/Placebo as an Aid for Smoking Cessation
The purpose of this study is to evaluate NicVAX as an aid to smoking cessation for long term abstinence.
- Conditions
- Smoking Cessation, Smoking, Tobacco Cessation
- Trial name
- NCT00836199
- Testing
- NicVAX vaccine
- Where
- 22 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Nabi Biopharmaceuticals
Nicotine Addiction
Effects of ABT-089 on Smoking Abstinence Symptoms and Reward
This Phase IIa within-subject, cross-over pilot study will evaluate the effects of ABT-089 (an experimental medication not approved by the FDA) when administered as 40mg oral once daily dose for 10 days, compared to placebo, on…
- Trial name
- NCT01756053
- Testing
- ABT-089
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Pennsylvania
Cigarette Smoking, Hypertension
Smoking Study With Behavioral Therapy for Hypertensive Patients
In total, 260 patients with pre- and stage I hypertension, who are regular smokers, will be randomized to: varenicline alone or varenicline plus behavioral therapy.
- Trial name
- VANQUISH (NCT00879177)
- Testing
- Varenicline, behavioral therapy
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- UConn Health
Tobacco Use Disorder, Tobacco Smoking
Brain Imaging in Tobacco Smokers During a Quit Attempt
The proposed study will help fill gaps in existing research by determining if nicotine-dependent cigarette smokers show changes in α7 nicotinic acetylcholine receptor (nAChR) availability when compared to matched historical…
- Trial name
- NCT04055467
- Testing
- [F18]-ASEM (3-(1,4-diazabicyclo[3.2.2]nonan-4-yl)-6-[18F]fluorodibenzo[b,d]thiophene 5,5-dioxide), Contingency Management
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Nicotine Dependence, Smoking
The Effect of Exercise on Acute Nicotine Withdrawal
The primary aim of this project is to test the effect of exercise on acute nicotine withdrawal. Acute nicotine withdrawal is characterized by a complex array of symptoms associated with increased risk of relapse among individuals…
- Conditions
- Nicotine Dependence, Smoking, Sleep Disorders, Intrinsic
- Trial name
- NicEx (NCT01047930)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Precancerous Conditions
Photographic Evidence of Oral Precancerous Lesions in Current Tobacco and Areca Nut Users Improves Their Quit Rates
The success of tobacco and areca nut cessation programs in individuals with Oral Potentially Malignant Disorders (OPMDs) is imperative for risk reduction and prevention of oral cancer.
- Trial name
- NCT05215860
- Testing
- Tobacco and areca nut cessation counselling with standard management for Oral Potentially Malignant Disorders, visual exposure to personal intraoral photographs of oral lesions at baseline and review
- Where
- India
- Volunteers
- 200 people
- Sponsor
- All India Institute of Medical Sciences
Hospitalized Smokers, Chronic Diseases
Enhancing Tobacco Abstinence Following Hospitalization
The primary aim of this study is to examine the efficacy of a 12-week nurse-delivered relapse management intervention designed with conceptual underpinnings from Self-efficacy Theory to enhance smoking abstinence of hospitalized…
- Conditions
- Hospitalized Smokers, Chronic Diseases, Tobacco Use Disorder
- Trial name
- NCT00222703
- Testing
- Smoking relapse prevention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pittsburgh
Tobacco Use Disorder, Schizophrenia
Smoking Abstinence and Lapse Effects in Smokers With Schizophrenia and Controls
This project tests two hypotheses concerning the low smoking cessation rates in smokers with schizophrenia. The first hypothesis is that smokers with schizophrenia experience stronger and more sustained effects of smoking…
- Trial name
- WREN (NCT01214005)
- Testing
- smoking abstinence
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brown University
Smokeless Tobacco Use
Highdose Nicotine Patch Therapy for Smokeless Tobacco Use
Smokeless tobacco use ("chewing") is associated with negative health effects. To date, no medications have been shown to help chewers quit long-term.
- Trial name
- NCT00939029
- Testing
- nicotine replacement therapy (nicotine patches)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Tobacco Smoking, Tobacco Withdrawal
Effectiveness of Combined Tobacco Treatment in Hospitalized Subjects
In the 20th century, tobacco caused the death of 100 million people worldwide and it is estimated that it will be responsible for 1 billion deaths in the 21st century.
- Conditions
- Tobacco Smoking, Tobacco Withdrawal, Nicotine Addiction, Nicotine Withdrawal
- Trial name
- NCT06254001
- Testing
- Bupropion, Nicotine replacement therapy (Nicotine patches)
- Where
- Mexico
- Volunteers
- 134 people
- Sponsor
- National Institute of Respiratory Diseases, Mexico
Cardiovascular Diseases, Heart Diseases
Education and Counseling for Abstinence From Tobacco After Pregnancy
The purpose of this study is to develop and field test a maintenance of smoking abstinence program designed for a predominately low-income, high-risk population of women from a wide variety of ethnic and racial backgrounds who…
- Trial name
- NCT00139529
- Testing
- Motivational Interviewing Telephone Counseling, Educational Intervention
- Where
- United States
- Volunteers
- 757 people
- Sponsor
- Brown University
Smoking
Web and Mobile Smoking Cessation
This study seeks to develop and then perform a controlled efficacy Randomized Controlled Trial assessing tobacco abstinence of a best-practices Web-based PC-delivered smoking cessation intervention (QuitOnline) compared to a…
- Trial name
- MobileQuit (NCT01952236)
- Testing
- Web+Mobile, Web Only
- Where
- United States
- Volunteers
- 1,266 people
- Sponsor
- Oregon Research Institute
Smoking
The Potential of Kava in Enabling Tobacco Cessation - Its Holistic Effects in Managing Stress and Insomnia Associated With Abstinence
This study will evaluate the compliance with a daily kava regimen among active smokers who have an intention to quit smoking. This study will also investigate whether kava use can facilitate tobacco cessation, reduce stress, and…
- Trial name
- NCT05814055
- Testing
- AB-free kava
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Florida
Cigarette Smoking
A Smoking Cessation Study to Understand the Biological and Functional Changes After One Year of Smoking Cessation
The purpose of this study was to understand the biological and functional changes after one year of smoking cessation and to collect data on a broad range of biomarkers of exposure (BoExp) and biomarkers of effect (BoE).
- Trial name
- RIBESC (NCT02432729)
- Where
- 5 sites in United States, Germany and 3 more
- Volunteers
- 1,184 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Tobacco Use Disorder
Effect of Galantamine on Short-term Abstinence
This is a randomized, double-blind, placebo-controlled study to test whether a medication called galantamine (Brand Name: Razadyne) will help smokers quit and whether it reduces cognitive problems that smokers experience during a…
- Trial name
- GAL-K (NCT01669538)
- Testing
- Galantamine
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Pennsylvania
Smoking, Tobacco
A Study to Determine the Effect of Access to Multiple Tobacco Flavor Options on Smoking Abstinence Among Primary Cigarette Smokers Using an Electronic Nicotine Delivery System
This is a multi-site, open-label, single arm study to evaluate the rate of smoking abstinence by the end of the study with healthy adult consumers of cigarettes when provided with an e-cigarette over a 13 week study period.
- Trial name
- NCT07879638
- Testing
- FT25614, FT25615, FT25616
- Where
- 5 sites in United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Smoking, Tobacco
A RCT to Determine the Effect of ENDS Flavor Availability on Abstinence Within Smokers
The overall purpose of this study will be to assess primary combustible cigarette users' abstinence from smoking their usual brand of combustible cigarettes at the end of the study, when provided with an electronic nicotine…
- Trial name
- NCT07172438
- Testing
- P2611222, P2615022, P2615122
- Where
- 27 sites in United States
- Volunteers
- 668 people, healthy volunteers welcome
- Sponsor
- RAI Services Company