Clinical trials: To Assess Cardiovascular Function
Diabetes
Diabetes Interventional Assessment of Slimming or Training to Lessen Inconspicuous Cardiovascular Dysfunction
There is an epidemic of type 2 diabetes in younger adults. These patients are at very high lifetime risk of heart-related complications.
- Trial name
- Diastolic (NCT02590822)
- Testing
- Cambridge Weight Plan, Supervised Exercise Sessions
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Stroke
Smartphone and 3D Printing Based Home Rehabilitation System for Chronic Stroke
Interventions promoting optimum motor performance across the lifespan are a priority after a neurological insult such as stroke.
- Trial name
- NCT04363944
- Testing
- mRehab
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- State University of New York at Buffalo
Mitral Regurgitation
Left Chamber Function in Mitral Regurgitation and Predicting Outcome After Replacement and Targeting for Early Surgery
The study aims to analyze the role of left ventricular and left atrial functional parameters by speckle tracking echocardiography in predicting outcome after mitral valve replacement and targeting for early intervention compared…
- Trial name
- NCT03870516
- Testing
- Mitral valve replacement, Speckle tracking echocardiography
- Volunteers
- 100 people
- Sponsor
- Assiut University
Stroke
The Assessment of Knee Joints Function in People After Stroke
The study aims to assess the function of knee joints in patients after stroke compared to healthy people and evaluate the impact of rehabilitation on the function of knee joints in people after stroke.
- Trial name
- NCT06746493
- Testing
- Rehabilitation
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Cardiovascular Disease
Effects of a Beverage Rich in Fruit Extracts on Risk Factors Associated With Cardiovascular Disease
The purpose of this study is to assess the effects of a novel beverage rich in polyphenols (compounds present in fruit extracts) on risk factors associated with cardiovascular disease.
- Trial name
- NCT00795834
- Testing
- High polyphenol beverage
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Tricuspid Regurgitation, Heart Failure With Preserved Ejection Fraction
Enavogliflozin Outcome Trial in Functional Tricuspid Regurgitation
The Enavogliflozin Outcome Trial in Functional Tricuspid Regurgitation (EVENT) was designed to examine the hypothesis that, compared with placebo, therapy with the SGLT2 inhibitor enavogliflozin would improve clinical and…
- Trial name
- EVENT (NCT06027307)
- Testing
- Enavogliflozin
- Where
- 5 sites in South Korea
- Volunteers
- 541 people
- Sponsor
- Asan Medical Center
Ischemic Stroke
Stroke Recovery and Music or No Music
The primary outcome of this study is to determine the quantitative increase in connectivity, as measured by fMRI brain and calculated as a percent increase from baseline in patients with ischemic stroke.
- Trial name
- NCT03608904
- Testing
- Music listening, Spoken word (language) listening
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Methodist Hospital Research Institute
Stroke, Broca's Aphasia
Assessment of Cortical Stimulation Combined With Rehabilitation to Enhance Recovery in Broca's Aphasia.
The primary objective of this feasibility study is to evaluate the safety and effectiveness of targeted sub-threshold epidural cortical stimulation delivered concurrent with speech-language rehabilitation activities to enhance…
- Trial name
- NCT00170703
- Testing
- Cortical Electrical Stimulation
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Northstar Neuroscience
Atrial Fibrillation
Effects of Dronedarone on Cardiac Geometry and Function in Patients With Atrial Fibrillation and Left Atrial Enlargement
Primary Objective: Evaluate the effect of dronedarone versus placebo (standard therapy) in slowing the progression of adverse left atrial remodeling in patients with atrial fibrillation (AF) following 12 months of treatment.
- Trial name
- ODYSSEUS (NCT01198873)
- Testing
- Dronedarone
- Where
- 57 sites in United States, Canada
- Volunteers
- 76 people
- Sponsor
- Sanofi
Acute Coronary Syndrome
Tailored Antiplatelet Therapy Versus Recommended Dose of Prasugrel
The purpose of this study is to demonstrate the superiority of a strategy of platelet monitoring (Monitoring Arm) with down-adjustment of the dose of prasugrel in high responders and up-adjustment of the dose of prasugrel in low…
- Trial name
- ANTARCTIC (NCT01538446)
- Testing
- Modification of Prasugrel based on a biological assay, prasugrel / clopidogrel, Verify Now
- Where
- 2 sites in France
- Volunteers
- 880 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris