Clinical trials: Tissue Perfusion
Melanoma and Sarcoma
TITAN (Tumoural Injection of T-VEC and Isolated Limb Perfusion)
This study will look at the safety and effects of combining a new drug called Talimogene Laherparepvec (T-VEC) with chemotherapy delivered by Isolated Limb Perfusion (ILP).
- Trial name
- TITAN (NCT03555032)
- Testing
- Talimogene laherparepvec (T-VEC)
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Glioblastoma, Anaplastic Astrocytoma
Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade Glioma
The purpose of this study is to find out if performing additional Magnetic Resonance Image (MRI) scans of the subjects' brain during each week of the radiation treatment of their high-grade glioma will help improve the radiation…
- Conditions
- Glioblastoma, Anaplastic Astrocytoma, Astrocytoma, Anaplastic Oligodendroglioma
- Trial name
- NCT06108206
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Columbia University
Heart Diseases, Coronary Artery Disease
Influence of Non Invasive Mechanical Ventilation on Tissue Perfusion in Patients After Cardiac Surgery
This study evaluates whether noninvasive ventilation with continuous positive airway pressure affects tissue perfusion in patients after cardiac surgery.
- Trial name
- NCT02767687
- Testing
- Noninvasive ventilation
- Volunteers
- 80 people
- Sponsor
- Federal University of São Paulo
Renal Function Disorder, Critical Illness
Transcutaneous Electrical Nerve Stimulation for Tissues Perfusion
The aim of this study is to determine the effect of transcutaneous electrical nerve stimulation in mechanically ventilated patients on the lower limb and renal tissue perfusion.
- Conditions
- Renal Function Disorder, Critical Illness, Critical Illness Myopathy
- Trial name
- NCT04069871
- Testing
- trans-cutaneous electrical nerve stimulation.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Trauma
Use of Diffuse Optical Spectroscopy for Evaluation of the Trauma/Critically Care Patients
Trauma remains the leading cause of death and disability for Americans age 1-44. Trauma can cause internal bleeding, and this bleeding is often hard to detect without sophisticate tests that take time to complete and analyze.
- Trial name
- NCT00581295
- Testing
- Diffuse optical spectroscopy
- Where
- 2 sites in United States
- Volunteers
- 93 people
- Sponsor
- University of California, Irvine
Alzheimer Disease, Dementia
Evaluation of Age- and Alzheimer's Disease-Related Memory Disorder
The purpose of this study is to examine how a part of the brain called the hippocampus contributes to memory changes that occur with aging and Alzheimer's disease (AD). Memory problems are the most important early symptoms of AD.
- Conditions
- Alzheimer Disease, Dementia, Memory Disorder, Healthy
- Trial name
- NCT00029120
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Acute Circulatory Failure
Peripheral Tissue Perfusion in Intensive Care
Tissue perfusion has been identified as an early prognosis factor in patients admitted to intensive care. However, little is known about the effects of different hemodynamic interventions performed in clinical routine on…
- Trial name
- INPPEREA (NCT06384287)
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Open Angle Glaucoma, Normal Tension Glaucoma
Reproducibility of Blood Flowmetry in Human Retina Using the Nidek Laser Speckle Flowgraphy LSFG-NAVI System
In addition to intraocular pressure blood perfusion pressure in the optic nerve is an important factor determing the cause of glaucoma. Increasing evidence suggests that in glaucoma patients retinal blood may be decreased.
- Conditions
- Open Angle Glaucoma, Normal Tension Glaucoma, Healthy
- Trial name
- LSFG Repro (NCT04014933)
- Testing
- LASER SPECKLE FLOWGRAPHY
- Where
- Switzerland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Zurich