Clinical trials: Tissue Oxygenation
Postoperative Nausea and Vomiting, Hysterectomy
Effect of SmtO2 Guided Care on PONV (iMODIPONV)
This randomized controlled trial is to investigate if SmtO2-guided management on top of the usual care, compared with the usual care only, during laparoscopic hysterectomy significantly reduces the incidence of PONV.
- Conditions
- Postoperative Nausea and Vomiting, Hysterectomy, Tissue Oxygenation, Cardiac Output Management
- Trial name
- iMODIPONV (NCT03641625)
- Testing
- Muscular tissue oxygen saturation guided care
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Yale University
Breast Cancer, Shoulder Dysfunction
Effectiveness of a Visual Biofeedback Program Versus Conventional Physiotherapy on Shoulder Mobility, Strength, and Function in Women After Breast Cancer Surgery
This study aims to evaluate the effectiveness of a physiotherapy program incorporating visual biofeedback compared to a conventional physiotherapy program in improving shoulder function in women following breast cancer surgery.
- Trial name
- NCT07542106
- Testing
- Experimental Group: Physiotherapy + Visual Biofeedback
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Flap Ischemia, Hypoxia
Spectroscopic Assessment of Tissue Oxygenation Changes in Plastic Surgical Flap Reconstructions
This study is a single-center, observational study designed to collect tissue spectrometric data.
- Trial name
- NCT07786610
- Volunteers
- 30 people
- Sponsor
- Spectrocor
Ulcers
Effect of NIRS-assisted Assessment on Chronic Lower Extremity and Other Chronic Non-healing Ulcers
Investigation of the predictive value of Near Infrared Spectroscopy in Chronic Lower Extremity and Other Chronic non-healing Ulcers
- Trial name
- NCT06702852
- Testing
- NIRS imaging in addition to SOC
- Where
- 4 sites in United States
- Volunteers
- 221 people
- Sponsor
- Kent Imaging Inc
Effect of RBC Transfusions on Cerebral Oxygen Saturation
Monitoring the Effect of Red Blood Cell Transfusion on Cerebral Oxygen Saturation With Near Infrared Spectroscopy (NIRS) in Critically Ill Patients
Critically ill patients are frequently transfused with red blood cell (RBC) units with the predominant intention to increase arterial oxygen content and thus oxygen delivery to the tissues.
- Trial name
- NCT02232412
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Laparoscopy, Abdominal Wall
The Impact of Anterior Abdominal Wall Tissue Oxygenation During Pneumoperitoneum of Regional Anesthesia Methods
During laparoscopic surgery, the abdomen is inflated with carbon dioxide for abdominal imaging and increased intraabdominal pressure affects intraabdominal structures and abdominal wall.
- Conditions
- Laparoscopy, Abdominal Wall, Regional Anesthesia
- Trial name
- NCT03652506
- Testing
- regional oxymetry probe, Quadratus Lumborum block, Thoracic Epidural block
- Volunteers
- 90 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Muscle Fatigue and Muscle Oxygenation
Grastion and Percussion Therapy
The study aims to investigate the effects of percussion therapy and instrument-assisted soft tissue mobilization (AISM), commonly used in clinical settings, on muscle fatigue, maximum muscle strength, pain threshold, and muscle…
- Trial name
- NCT07389395
- Testing
- Percussion Therapy, Instrument-Assisted Soft Tissue Mobilization (AISM)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Hyperglycemia, Glucose Intolerance
Effect of Acute Hyperglycemia on Renal Tissue Oxygenation
Diabetes Mellitus (DM) includes several metabolic diseases all characterized by high sugar levels in the blood. Although diabetic nephropathy is widespread, its underlying pathophysiological mechanisms remain poorly understood…
- Trial name
- Glucox (NCT02346149)
- Testing
- glucose 20%
- Where
- Switzerland
- Volunteers
- 19 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Multiple Sclerosis
Exopulse Mollii Suit, Spasticity & Tissue Oxygenation
Spasticity is a frequent and debilitating symptom in patients with multiple sclerosis (MS). Sustained contractile activity, such as that observed in spastic muscles, could reduce the capillary density and induce important changes…
- Trial name
- ENNOX (NCT05362006)
- Testing
- Exopulse Mollii Suit
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Institut De La Colonne Vertebrale Et Des Neurosciences
Environmental Sleep Disorder, Cheyne-Stokes Respiration
Monitoring of the Cerebral Tissue Oxygenation and Perfusion in the Adapting Climber During Sleep in High Altitude
One of the major challenges in adapting to high altitudes is that with increasing altitude sleeping quality declines rapidly. Thus, the night sleep can only provide limited to none regeneration.
- Conditions
- Environmental Sleep Disorder, Cheyne-Stokes Respiration, Altitude Sickness
- Trial name
- PerOxySleep (NCT01465971)
- Where
- Germany
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Goethe University
Overweight
The Use of Diffuse Optical Spectroscopy to Characterize in Response to Weight-Loss Intervention
The first step in any clinical intervention against obesity involves sustained lifestyle changes. Researcher can use these strategies to beneficial the effects of weight and on cardiovascular risk.
- Trial name
- NCT02146885
- Testing
- Weight Control
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Neonates and Preterm Infants, Infant Respiratory Distress Syndrome
Duration of Surfactant Administration and Impact on Stabilisation of Vital Parameters in Very Preterm Neonates: 1 Minutes Versus 5 Minutes
Respiratory distress syndrome (RDS) is common in very preterm infants due to surfactant deficiency. Surfactant replacement therapy is lifesaving, and current guidelines recommend the less invasive surfactant administration (LISA)…
- Conditions
- Neonates and Preterm Infants, Infant Respiratory Distress Syndrome, Surfactant Deficiency Syndrome Neonatal, Surfactant
- Trial name
- SurfStab I (NCT07261787)
- Testing
- Poractant alfa (Curosurf®) - 1-minute administration, Poractant alfa (Curosurf®) - 5-minute administration
- Where
- Austria
- Volunteers
- 76 people
- Sponsor
- Medical University of Graz
Tourette's Syndrome, Chronic Motor Tic Disorder
Brain Activation in Vocal and Motor Tics
This study will investigate the brain areas that are activated by vocal and motor tics in patients with Tourette's syndrome and other tic disorders. Tics are involuntary repetitive movements similar to voluntary movements.
- Conditions
- Tourette's Syndrome, Chronic Motor Tic Disorder, Chronic Motor Vocal Disorder
- Trial name
- NCT00026000
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy
Explore the Use of Cortical Oxygenation Measures in Nutrition Research
The current project aims to explore the use of cortical oxygenation measures obtained with functional Near Infrared Spectroscopy (fNIRS) in acute nutrition interventions with outcomes on cognition.
- Trial name
- Saga (NCT07191665)
- Testing
- Acute nutrition intervention
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- Société des Produits Nestlé (SPN)
Necrotizing Enterocolitis
Early Predictors of Necrotizing Enterocolitis in Neonates
The goal of this project is to identify neonates who are predisposed to Necrotizing Enterocolitis (NEC). the investigators will determine the effectiveness of non-invasive measures as well as biochemical markers to identify…
- Trial name
- NCT03210831
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Preconditioning
Personalized Hypoxic-hyperoxic Preconditioning in Elderly People
This study investigates an original protocol of personalized hypoxic-hyperoxic preconditioning utilizing a personalized approach on the basis of cerebral tissue oxygenation assessed with near-infrared spectroscopy.
- Trial name
- NCT07018895
- Testing
- FiO2 reduced by 20% alternating with 34% FiO2
- Where
- Russia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Blood Gas Monitoring, Transcutaneous
Optical Transcutaneous Sensors of Capnia and Oxygenation
This study aims at validating new optical transcutaneous sensors to evaluate tissue capnia (CO2 partial pressure) and oxygenation (blood oxygen saturation) by comparing them to standard laboratory measurements (end tidal CO2…
- Trial name
- CTCO (NCT03992651)
- Testing
- Measurements of capnia and tissue oxygenation by optical transcutaneous sensors
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Malignant Glioma, High Grade Glioma
Accelerated Hypofractionated Intensity - Modulated Radiotherapy After Hyperbaric Oxygenation for Recurrent High Grade Glioma.
This is a pilot study of radiotherapy using Hypofractionated image - guided helical tomotherapy after hyperbaric oxygen HBO therapy for treatment of recurrent malignant High-grade gliomas.
- Conditions
- Malignant Glioma, High Grade Glioma, Recurrent Glioma
- Trial name
- HBO-RT (NCT03411408)
- Testing
- HBO, RT
- Where
- 3 sites in Italy
- Volunteers
- 24 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Obstructive Sleep Apnea Syndrome
Brain Oxygenation and Hemodynamics During Sleep in Obstructive Sleep Apnea Sufferers
The goal of this trial is to assess the performance of the OxiplexTS-an absolute near-infrared oximeter-as an instrument to measure brain oxygenation and hemodynamics in sleep medicine as well as in the broader field of…
- Trial name
- NIRS-OSAS (NCT00591591)
- Testing
- OxiplexTS
- Where
- 4 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- ISS, Inc.
Oxygen Deficiency
Validation of the O3 Regional Somatic Tissue Oxygenation Monitor
Testing the absolute accuracy of the Masimo O3 regional oximeter in reading somatic tissue oxygenation in healthy volunteers under controlled hypoxia.
- Trial name
- NCT04584788
- Testing
- Masimo O3 Regional Oximeter
- Where
- Netherlands
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation