Clinical trials: Tissue Oxygenation
Vascular Disease, Critical Lower Limb Ischemia
Pilot Study of Hemospan® in Patients With Chronic Critical Limb Ischemia
The purpose of this study is to evaluate the effects of Hemospan infusion on vascular reactivity, regional perfusion and oxygenation of ischemic tissue in patients with chronic critical lower limb ischemia.
- Trial name
- NCT00633659
- Testing
- Hemospan (MP4OX), Voluven (HES 130/0.4)
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Sangart
Transcutaneous Oxygen Tension
Comparative Study Evaluating Performance of Celliant Fibers on Tissue Oxygenation
The study will evaluate changes in transcutaneous oxygen tension (tcPO2,), and the inferred change in local cutaneous blood flow, in healthy subjects wearing a control and a 100% Celliant® fiber upper torso garment.
- Trial name
- NCT02798640
- Testing
- Celliant, Control
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Kristopher Washington
Peripheral Arterial Disease
Near Infrared Spectroscopy Imaging of Change in Tissue Oxygenation to Assess Peripheral Artery Disease
This is a proof-of-concept study with exploratory objective to assess whether superficial tissue oxygenation patterns measured by Snapshot NIRS, in conjunction with the Provocative Elevation Maneuver of the Lower Extremity…
- Trial name
- NCT07397494
- Testing
- Observational study only.
- Volunteers
- 200 people
- Sponsor
- Kent Imaging Inc
Angina Pectoris, Unstable Angina
Pilot Study of Hemoglobin Based Oxygen Therapeutics in Elective Coronary Revascularization
The purpose of this study is to assess the safety and feasibility of a novel oxygen carrying solution, HBOC-201, in the setting of PCI for Acute Coronary Syndromes from randomization til hospital discharge.
- Conditions
- Angina Pectoris, Unstable Angina, Myocardial Infarction
- Trial name
- NCT00317512
- Testing
- Percutaneous Coronary Revascularization, Hemoglobin-Based Oxygen Carrier-201 (HBOC-201), Voluven
- Where
- 6 sites in Belgium, Germany and 1 more
- Volunteers
- 45 people
- Sponsor
- Biopure Corporation
Flap Ischemia, Hypoxia
Spectroscopic Assessment of Tissue Oxygenation Changes in Plastic Surgical Flap Reconstructions
This study is a single-center, observational study designed to collect tissue spectrometric data.
- Trial name
- NCT07786610
- Volunteers
- 30 people
- Sponsor
- Spectrocor
Critical Limb Ischemia
Validation of OxyVu for Assessing Level of Amputation With Comparison to Other Modalities
Correlation of(OxyVu) values to to ABI, TBP, and TCOM in patients scheduled for foot level amputation because of critical limb ischemia, infection, or tissue necrosis.
- Trial name
- LOA (NCT00767923)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- HyperMed
Vascular Disease, Peripheral, Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)
Correlating Multispectral Near-Infrared Imaging to Standard Vascular Diagnostics
The goal of this observational study is to learn if the measures of tissue oxygenation from the MIMOSA Pro imaging device correlate to standard vascular assessment tools in patients who receiving a lower extremity vascular…
- Trial name
- NCT06899113
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- MIMOSA Diagnostics Inc.
Diabetic Foot Ulcers
Hyperspectral Imaging to Assess and Predict Diabetic Foot Ulcers
This study is designed to test a prototype imaging instrument that relies on Medical HyperSpectral Imaging (MHSI) technology for the assessment and prediction of diabetic foot ulceration and wound healing.
- Trial name
- NCT00617916
- Where
- 3 sites in United States
- Volunteers
- 256 people
- Sponsor
- HyperMed
Wounds
MolecuLight All-in-One Oxygenation Clinical Utility
This is a prospective, clinical evaluation of the MolecuLightDX+ with OxySight Module in wound care.
- Trial name
- NCT07646938
- Testing
- MolecuLightDX+ with OxySight Module
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- MolecuLight Inc.
Wounds and Injuries
Tissue Perfusion and Blood Flow Monitoring Technology
The purpose of this study is to investigate the safety and efficacy of an optical device designed and developed to quantitatively monitor blood flow velocity of wound sites.
- Trial name
- WoundImager (NCT01139567)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- CW Optics, Inc.
Tissue Oxygenation
Accuracy Verification of the INVOS PM7100
Prospective, observational, pre-market, verification study to confirm accuracy of the INVOS 7100 system in compliance with ISO 80601-2-85:2021 standard
- Trial name
- NCT07166341
- Testing
- Observational
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Obstructive Sleep Apnea Syndrome
Brain Oxygenation and Hemodynamics During Sleep in Obstructive Sleep Apnea Sufferers
The goal of this trial is to assess the performance of the OxiplexTS-an absolute near-infrared oximeter-as an instrument to measure brain oxygenation and hemodynamics in sleep medicine as well as in the broader field of…
- Trial name
- NIRS-OSAS (NCT00591591)
- Testing
- OxiplexTS
- Where
- 4 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- ISS, Inc.
Incontinence-associated Dermatitis, Decubitus Ulcer
Safety and Efficacy of RashEndZ Wound Aeration Technology
The aim of this study is to determine the safety and efficacy of RashEndZ therapeutic liner technology and Dynamic Oxygen Skin Therapy in improving symptoms and expediting healing of IAD and DU in adult patients.
- Trial name
- NCT07899060
- Testing
- Dynamic Oxygen Skin Therapy (DOST), Standard Wound Care
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- RashEndZ Inc.
Ulcers
Effect of NIRS-assisted Assessment on Chronic Lower Extremity and Other Chronic Non-healing Ulcers
Investigation of the predictive value of Near Infrared Spectroscopy in Chronic Lower Extremity and Other Chronic non-healing Ulcers
- Trial name
- NCT06702852
- Testing
- NIRS imaging in addition to SOC
- Where
- 4 sites in United States
- Volunteers
- 221 people
- Sponsor
- Kent Imaging Inc
Oxygen Deficiency
Validation of the O3 Regional Somatic Tissue Oxygenation Monitor
Testing the absolute accuracy of the Masimo O3 regional oximeter in reading somatic tissue oxygenation in healthy volunteers under controlled hypoxia.
- Trial name
- NCT04584788
- Testing
- Masimo O3 Regional Oximeter
- Where
- Netherlands
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Healthy
Explore the Use of Cortical Oxygenation Measures in Nutrition Research
The current project aims to explore the use of cortical oxygenation measures obtained with functional Near Infrared Spectroscopy (fNIRS) in acute nutrition interventions with outcomes on cognition.
- Trial name
- Saga (NCT07191665)
- Testing
- Acute nutrition intervention
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- Société des Produits Nestlé (SPN)
Mental Fatigue
Brain Oxygenation Marker for Cognitive Function in Healthy Adults
This study aims to identify a cortical oxygenation marker for cognitive function using functional Near Infrared Spectroscopy in healthy adults.
- Trial name
- NCT05559034
- Testing
- Cognitive intervention
- Where
- Switzerland
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Wounds
Outcome Assessment in Patients Treated With Hyperbaric Oxygen Using OxyVu Tissue Oxygenation Monitoring System
The objective is to define patient eligibility for hyperbaric oxygen therapy and to evaluate wound healing progression using a new hyperspectral imaging technology.
- Trial name
- HBOT (NCT00768027)
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- HyperMed
Left-sided Colorectal Resection : Diverticular Diseases, Left-sided Colorectal Resection : Colonic Neoplasms
InTRaoperative Imaging DEvice Based on endogeNous opTical Properties to Evaluate Bowel Oxygenation in Colorectal Resections
The objective of the study is to assess the safety and technical feasibility of a new imaging system, used during colorectal resection surgery, named Trident in version 1.0, which could be used by the surgeon during colorectal…
- Conditions
- Left-sided Colorectal Resection : Diverticular Diseases, Left-sided Colorectal Resection : Colonic Neoplasms, Left-sided Colorectal Resection : Rectal Neoplasms
- Trial name
- TRIDENT (NCT05973227)
- Testing
- use of the TRIDENT system
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Intuitive Surgical
Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
Spectroscopic Assessment of Tissue Oxygenation Changes During Vascular Surgery
This study is a single-center, observational study designed to collect tissue spectrometric data related to tissue oxygenation.
- Conditions
- Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia, Ischemia Vascular, Tissue Ischemia
- Trial name
- NCT07786623
- Volunteers
- 30 people
- Sponsor
- Spectrocor