Clinical trials: Tissue Ischemia
Acute Ischemic Stroke
Phase 3, Randomized, Placebo-Controlled, Double-Blinded Trial of the Combined Lysis of Thrombus With Ultrasound and Systemic Tissue Plasminogen Activator (tPA) for Emergent Revascularization in Acute Ischemic Stroke
This is a randomized, placebo-controlled, phase 3 clinical trial to evaluate the efficacy and safety of transcranial ultrasound (US) as an adjunctive therapy to tissue plasminogen activator (tPA) treatment in subjects with acute…
- Trial name
- CLOTBUST-ER (NCT01098981)
- Testing
- Transcranial ultrasound as an adjunctive therapy to tPA, Standard of care tPA therapy for acute ischemic stroke
- Where
- United States
- Volunteers
- 675 people
- Sponsor
- Cerevast Therapeutics, Inc.
Ischemic Stroke
Efficacy and Safety of SP-8203 (Otaplimastat) in Patients With Acute Ischemic Stroke Receiving Thrombolytic Standard of Care
This clinical study is designed to evaluate the efficacy and safety of the combination therapy of SP-8203 (otaplimastat) and thrombolytic standard of care in acute ischemic stroke patient.
- Trial name
- SP-8203-3001 (NCT06660719)
- Testing
- SP-8203
- Where
- 2 sites in South Korea
- Volunteers
- 852 people
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.