Clinical trials: Tinnitus
Tinnitus
An fMRI Investigation of the Effects of IV Lidocaine on Tinnitus
This is an exploratory pilot open-label study to identify the signal changes on fMRI of patients with tinnitus and with temporary suppression of the tinnitus with IV lidocaine.
- Trial name
- NCT04192773
- Testing
- IV Lidocaine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- D. Bradley Welling, MD, PhD
Tinnitus, Hearing Loss
Neuromodulation Techniques in the Treatment of Chronic Tinnitus With Hearing Loss
This study aimed at trying transcranial magnetic stimulation and transcranial direct current stimulation as potential treatments to decrease tinnitus in patients with significant hearing loss.
- Trial name
- NCT01944501
- Testing
- Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Brasilia
Tinnitus
Using PET-CT to Target and Validate Low-frequency TMS as Treatment for Tinnitus
One out of every five people experience tinnitus (a buzzing, ringing, or roaring sound in the ear) ranging from mild to severe impairment. To date there is no effective therapy that seems to help the tinnitus sufferer.
- Trial name
- NCT00329524
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Chronic Tinnitus
Short-term Effects of Oxytocin Nasal Spray on Chronic Tinnitus
The study compares the short-term tinnitus reduction following a single oxytocin intervention with a placebo control condition.
- Trial name
- NCT02508220
- Testing
- Syntocinon
- Volunteers
- 15 people
- Sponsor
- Berthold Langguth, MD, Ph.D.
Profound Hearing Impairment
Positron Emission Tomography Imaging of Brain Reorganisation of the Central Auditory Cortex in Asymetrical Profound Deaf Patient With a Cochlear Implantation.
Our main objective is to study how the extent of reorganization of the central auditory system is related to the binaural integration in cochlear implanted subjects with asymmetric hearing loss.
- Trial name
- UniTEP (NCT03117413)
- Testing
- Positron emission tomography scan
- Where
- 2 sites in France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Tinnitus
Vagus Nerve Stimulation (VNS) Paired With Tones for Tinnitus
Assess the safety and efficacy of VNS paired with tones for tinnitus using a randomized, controlled, parallel study design.
- Trial name
- NCT01962558
- Testing
- VNS Treatment, VNS Control
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- MicroTransponder Inc.
Tinnitus
Comparison of an Internet-based Guided Self-help and a Group Therapy for Chronic Tinnitus
The aim of this study is to compare the efficacy of an internet-based guided self-help training for chronic tinnitus with a well-established outpatient group therapy and a discussion forum group.
- Trial name
- MINT (NCT01205906)
- Testing
- Internet-based guided self-help for tinnitus, Cognitive-behavior group therapy for tinnitus, Internet discussion forum
- Where
- Germany
- Volunteers
- 128 people
- Sponsor
- Johannes Gutenberg University Mainz
Hearing Loss, Sensorineural, Tinnitus
Evaluation of the Clinical Benefit of the Hearing Aids Tinnitus Feature.
Participants with hearing loss and Tinnitus will wear hearing aids with amplification-only or with an added sound, and have their tinnitus level evaluated before and after intervention.
- Trial name
- NCT05292534
- Testing
- hearing aid amplification, hearing aid amplification with an added sound
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Sonova AG
Tinnitus
Tinnitus Sound Therapy Using Mobile Application.
Over the years Tinnitus Sound Therapy (TST) has been undergoing rigorous modification according to the availability of various technologies such as Hearing Aids, personal amplification devices, mp3 players, and now mobile phones.
- Trial name
- TST (NCT06104865)
- Testing
- Tinnitus Sound Therapy using (Resound Tinnitus relief) mobile application
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dr. Basel Samman
Tinnitus, Temporomandibular Joint Disorders
CBCT and Audiological Analysis of the TMJ-Tinnitus Relationship
The aim of this study is to investigate the relationship between Temporomandibular Disorders (TMD) and subjective tinnitus at both morphological and functional levels.
- Conditions
- Tinnitus, Temporomandibular Joint Disorders, Somatosensory Tinnitus, Osteoarthritis, Temporomandibular Joint
- Trial name
- NCT07460193
- Testing
- Cone Beam Computed Tomography (CBCT), Audiological Assessment, Clinical TMJ Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kutahya Health Sciences University
Perilymphatic Fistulas
Imaging Perilymphatic Fistulas After Barotrauma
Our objective is to validate the CT / MRI combination of non-injected rock for the rapid positive diagnosis of perilymphatic fistulas.
- Trial name
- NCT03543293
- Where
- France
- Volunteers
- 101 people
- Sponsor
- University Hospital, Strasbourg, France
Tinnitus
Treatment Evaluation of Neuromodulation for Tinnitus - Stage A3
TENT-A3 is a single arm repeated measures prospective investigation evaluating the safety and efficacy of the Lenire device for tinnitus treatment.
- Trial name
- TENT-A3 (NCT05227365)
- Testing
- Lenire
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 112 people
- Sponsor
- Neuromod Devices Ltd.
Tinnitus, Acoustic Stimulation
Different Stimuli Were Given to Patients With Chronic Pure Tone Tinnitus to Verify the Effective Treatment of Tinnitus.
In this experiment, patients with chronic pure tone tinnitus were divided into three groups to receive auditory stimulation, somatosensory stimulation, vestibular stimulation and combined stimulation, in order to find an…
- Conditions
- Tinnitus, Acoustic Stimulation, Somatic Stimulation, Vestibular Stimulation
- Trial name
- NCT04118907
- Testing
- multiple sensory stimulation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Dan Su
Subjective Tinnitus
Effect of Gabapentin on Idiopathic Subjective Tinnitus
The purpose of this study is to determine wether Gabapentin which is useful for treating neuropathic pains, is effective on idiopathic subjective tinnitus.
- Trial name
- NCT00555776
- Testing
- Gabapentin
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Islamic Azad University of Mashhad
Tinnitus, Subjective, Obstructive Sleep Apnea
Efficacy of Walking Exercise With Dog on Tinnitus Complaints in Sleep Apnea (Obstructive Sleep Apnea)
there is evidence that tinnitus (chronic subjective form) is highly prevalent among patients with obstructive sleep apnea. exercise is recommneded in chronic subjective form) and obstructive sleep apnea.
- Trial name
- NCT06803095
- Testing
- free walking with dog and diet restriction, diet restriction
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Tinnitus
A Comparison of the Benefits of Mindfulness Based Cognitive Therapy, Relaxation Therapy and a Waiting List Control in the Management of Distress in Chronic Tinnitus Patients
The principal hypotheses to be tested is that Mindfulness Based Cognitive Therapy (MBCT) reduces the distressing impact of tinnitus to a significantly greater extent than a waiting list control or relaxation therapy.
- Trial name
- NCT02059447
- Testing
- No treatment waiting period, Mindfulness Based Cognitive Therapy, Relaxation Therapy
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- University College London Hospitals
Chronic Tinnitus
Conventional Repetitive Transcranial Magnetic Stimulation for Tinnitus Treatment
The objective of the investigators study is to assess conventional repetitive transcranial magnetic stimulation (rTMS) in patients with chronic severe tinnitus.
- Trial name
- MagTIN (NCT01407133)
- Testing
- transcranial magnetic stimulator (class 2b) Medtronic © MagPro X100 (with MagOption) stimulator and Butterfly Coil MCF-B65 (figure-8 coil with fluid cooling)
- Where
- 3 sites in France
- Volunteers
- 64 people
- Sponsor
- Hospices Civils de Lyon
Tinnitus
Cognitive Training for Firefighters With Tinnitus
The purpose of this research study is to determine whether the Brain Fitness Program-Tinnitus affects how tinnitus is perceived and if its use aids in the recovery of cognitive functions that may be affected by tinnitus.
- Trial name
- FEMAICT (NCT01458821)
- Testing
- Brain Fitness Program - Tinnitus
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Chronic Tinnitus
Influence of Treatment Duration and Stimulation Frequency on rTMS in Chronic Tinnitus
Patients receive two weeks of treatment (prefrontal high-frequency and bilateral low-frequency rTMS vs. prefrontal high-frequency and bilateral high-frequency rTMS).
- Trial name
- NCT02653547
- Testing
- standard multisite four weeks, high-frequency multisite four weeks, standard multisite two weeks
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- University of Regensburg
Tinnitus
Assessment of Customized Bimodal Stimulation for Tinnitus
The research objective of the proposed usability study is to assess the compliance and acceptance/satisfaction of using a bimodal stimulation device with the modification of the sound stimulus to the participant's tinnitus pitch.
- Trial name
- NCT07092033
- Testing
- Bimodal Neuromodulation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Minnesota