Clinical trials: Tinnitus
Tinnitus
Tinnitus Measured by MEG and Synchronous Neural Interaction™ Test: Template Development
The study is designed to identify specific patterns of brain functional activity associated with chronic, moderate to severe tinnitus through the use of resting-state MEG scans.
- Trial name
- NCT01185990
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Orasi Medical, Inc.
Tinnitus
Deep TMS of the Left Auditory Cortex Using the HMCIPCC Coil, in the Treatment of Patients With Tinnitus.
The study is a double-blind study designed to evaluate the efficacy of deep transcranial magnetic stimulation (deep TMS) of the left auditory cortex using the HMCIPCC coil, in the treatment of patients with tinnitus
- Trial name
- NCT02053961
- Testing
- Deep Transcranial Magnetic Stimulation
- Where
- Israel
- Sponsor
- Brainsway
Tinnitus, Subjective, Tinnitus, Bilateral
Tinnitus Patient Preferences Survey
The goal of this survey is to assess several aspects related to patient preferences regarding interventions for alleviating tinnitus through invasive electrical brain stimulation (neuromodulation).
- Conditions
- Tinnitus, Subjective, Tinnitus, Bilateral, Tinnitus, Noise Induced, Tinnitus, Hearing Loss, Cochlear Implant Users
- Trial name
- NCT06782308
- Testing
- Survey using a questionnaire.
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Nicolas Gninenko
Tinnitus
Study of Low Level Laser Therapy and Tinnitus Relief
The purpose of this study is to determine if low level laser light therapy might help to relieve tinnitus in adults.
- Trial name
- NCT00845975
- Testing
- Erchonia Hearing Lasers #1 & #2
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Erchonia Corporation
Tinnitus, Subjective
Safety and Efficacy of Acupressure Applied Through ForgTin© in Patients With Tinnitus
The main objective of this clinical trial is to evaluate the effectiveness and safety of the medical product ForgTin with regard to the impairment and change in the sensation of tinnitus (volume, frequency, psychological stress).
- Trial name
- NCT04623957
- Testing
- ForgTin©
- Volunteers
- 35 people
- Sponsor
- Pansatori GmbH
Tinnitus
Vagus Nerve Stimulation (VNS) Paired With Tones for Tinnitus
Assess the safety and efficacy of VNS paired with tones for tinnitus using a randomized, controlled, parallel study design.
- Trial name
- NCT01962558
- Testing
- VNS Treatment, VNS Control
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- MicroTransponder Inc.
Hearing Loss, Sensorineural, Tinnitus
Evaluation of the Clinical Benefit of the Hearing Aids Tinnitus Feature.
Participants with hearing loss and Tinnitus will wear hearing aids with amplification-only or with an added sound, and have their tinnitus level evaluated before and after intervention.
- Trial name
- NCT05292534
- Testing
- hearing aid amplification, hearing aid amplification with an added sound
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Sonova AG
Tinnitus
Treatment Evaluation of Neuromodulation for Tinnitus - Stage A3
TENT-A3 is a single arm repeated measures prospective investigation evaluating the safety and efficacy of the Lenire device for tinnitus treatment.
- Trial name
- TENT-A3 (NCT05227365)
- Testing
- Lenire
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 112 people
- Sponsor
- Neuromod Devices Ltd.
Tinnitus
AM-101 in the Treatment of Acute Tinnitus 3
The purpose of this research study is to test the safety and effectiveness of the study drug, AM-101. AM-101 is tested for the treatment of tinnitus that started as the result of an injury to the inner ear or due to middle ear…
- Trial name
- TACTT3 (NCT02040194)
- Testing
- AM-101
- Where
- Germany
- Volunteers
- 893 people
- Sponsor
- Auris Medical AG
Tinnitus
Sub-chronic Neurostimulation Delivered in the Middle Ear for Tinnitus Suppression
The objectives of this study are to evaluate the safety and efficacy of applying electrical stimulation on the promontorium (EPS) for the suppression of tinnitus in a sub-chronic stimulation regimen.
- Trial name
- NCT01549145
- Testing
- Nimbus Multifunctional Stimulator
- Where
- Israel
- Volunteers
- 14 people
- Sponsor
- EstimME Ltd.
Treatment of Symptomatic Lateral Sinus Stenosis, Treatment of Pulsatile Tinnitus Due tu Sinus Stenosis
SiREX-Stent for the Treatment of SymptOmatic Lateral VEnous Sinus Stenosis
The purpose of the study is to assess the efficacy, safety and the clinical benefit of the SiREX stent for the treatment of disabling pulsatile tinnitus due to stenosis of lateral sinus.
- Trial name
- RESOLVE (NCT06726928)
- Testing
- Sinus Stenting
- Where
- France
- Volunteers
- 78 people
- Sponsor
- Acandis GmbH
Subjective Tinnitus
Efficacy, Safety and Tolerability of Neramexane in Patients With Subjective Tinnitus
The purpose of this study is to investigate the safety and efficacy of neramexane mesylate in the treatment of subjective tinnitus in comparison to placebo.
- Trial name
- EASE (NCT00739635)
- Testing
- Neramexane mesylate
- Where
- 54 sites in Austria, Germany and 3 more
- Volunteers
- 411 people
- Sponsor
- Merz Pharmaceuticals GmbH
Tinnitus
AM-101 in the Treatment of Acute Tinnitus 2
The purpose of this research study is to test the safety and effectiveness of the study drug, AM-101. AM-101 is tested for the treatment of tinnitus that started as the result of an injury to the inner ear or due to middle ear…
- Trial name
- TACTT2 (NCT01803646)
- Testing
- AM-101
- Where
- United States
- Volunteers
- 343 people
- Sponsor
- Auris Medical, Inc.
Meniere's Disease
SPI-1005 for the Treatment of Patients With Meniere's Disease
This study will evaluate the safety, efficacy, and Pharmacokinetics (PK) of two dose levels of SPI-1005 administered for 28 days compared to placebo in patients with Meniere's disease.
- Trial name
- NCT03325790
- Testing
- 200mg SPI-1005 BID, 400mg SPI-1005 BID
- Where
- 13 sites in United States
- Volunteers
- 149 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Tinnitus, Subjective, Cupping Therapy
Wet Cupping Therapy as an Integrative Medicine Treatment for Subjective Tinnitus
Cupping therapy is an ancient complementary medicine therapy. It was a cornerstone in many ancient healing systems, including Traditional Chinese Medicine, Unani Medicine, Traditional Korean Medicine, and Islamic Medicine.
- Trial name
- NCT07685171
- Testing
- Wet Cupping Therapy plus Usual care, usual care only
- Volunteers
- 142 people
- Sponsor
- Hamad Medical Corporation
Tinnitus, Tinnitus, Subjective
Noninvasive Therapy for Tinnitus
The goal of this interventional clinical study is to establish mild therapeutic hypothermia, delivered non-invasively to the structures of the inner ear, as a safe and repeatable therapeutic method for symptomatic relief of…
- Trial name
- NCT07071480
- Testing
- Cold pack-delivered mild therapeutic hypothermia
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Restorear Devices LLC
Sensorineural Hearing Loss, Tinnitus
Effect of a Totally Implantable Cochlear Implant on Tinnitus Severity in Adults With Preoperative Tinnitus
The purpose of this study is to investigate the degree of benefit to tinnitus symptoms by using a Totally Implantable cochlear implant (TICI) in a group of patients who have moderate-to-severe tinnitus pre-operatively.
- Trial name
- EXCITE (NCT07893860)
- Testing
- Cochlear implant
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- Cochlear
Tinnitus
Treatment Evaluation of Neuromodulation for Tinnitus (TENT-A)
This is a three arm, patient subtyping and parameter optimisation study for a neuromodulation treatment for tinnitus.
- Trial name
- NCT02669069
- Testing
- PS1, PS2, PS3
- Where
- 2 sites in Germany, Ireland
- Volunteers
- 326 people
- Sponsor
- Neuromod Devices Ltd.
Hearing Loss, Noise-Induced, Hearing Loss
Apple Hearing Study
The Apple Hearing Study is a partnership between the University of Michigan and Apple to study sound exposure and its impact on hearing health.
- Conditions
- Hearing Loss, Noise-Induced, Hearing Loss, Tinnitus
- Trial name
- AHS (NCT04172766)
- Where
- United States
- Volunteers
- 300,000 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Meniere's Disease, Ménière's Disease
SPI-1005 for the Treatment of Meniere's Disease (Open Label)
Study of the safety of open-label SPI-1005 400 mg BID treatment in adults with Meniere's Disease (MD) for 6 or 12 months to support chronic or chronic intermittent use.
- Trial name
- NCT06859788
- Testing
- Ebselen
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- Sound Pharmaceuticals, Incorporated