Clinical trials: Time Management
Healthy Participants, Obesity
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.
The purpose of the study is to assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD1043 following single and multiple ascending doses in healthy adult participants living with overweight and/or…
- Trial name
- NCT07511205
- Testing
- AZD1043
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Medication Administered in Error, Medication Compliance
The IMPROVE Study-IMPact of a Regulated ADC System
An automated dispensing cabinet (ADC) is a computerized drug storage device or cabinet designed for hospitals. ADCs allow medications to be stored and dispensed near the point of care while controlling and tracking drug…
- Trial name
- IMPROVE (NCT02228694)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hackensack Meridian Health
T1DM
RCT for Evaluation of Insulin Administration,While Using the iPORT System
Type 1 diabetes is the most common chronic pediatric autoimmune disease, with a rising incidence rate in recent years around the world and in Israel Management includes multiple daily capillary glucose measurements by finger…
- Trial name
- NCT04421001
- Testing
- I-port use
- Volunteers
- 35 people
- Sponsor
- Assaf-Harofeh Medical Center
Obesity (Disorder)
Exercise Supervision Duration and Adherence in Obese Women
Obesity is one of the most common health problems worldwide and is associated with many chronic diseases. Regular physical activity is known to play an important role in weight control, balance, quality of life, and mental…
- Trial name
- NCT07152028
- Testing
- Exercise program with supervised and home-based components, Fully supervised exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Pamukkale University
Mildly Hypercholesterolemic Subjects
Pilot Study in the Cholesterol Absorption Reduction After Consumption of Low-fat, Drinkable Fermented Milk Enriched With Plant Sterols
The objective of this study is to compare efficacy of a plant sterol enriched yogurt given at different moments of the day in lowering blood cholesterol of hypercholesterolemic.
- Trial name
- NCT01571869
- Testing
- 1- Low fat drinkable fermented dairy product enriched with 1.6g of plant sterol (as free equivalent) per unit, 2- Low fat drinkable fermented dairy product without plant sterols (control)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Endocarditis
Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL)
The purpose of this study is to determine the safety and compliance of initial intravenous (IV) antibiotics followed by oral antibiotic therapy following uncomplicated IVDA endocarditis.
- Trial name
- OPTIMAL (NCT05156437)
- Testing
- Amoxycillin, Cefalexin, Dicloxacillin, Linezolid, Levofloxacin, Rifampicin, Ampicillin, Oxacillin, Vancomycin, Daptomycin, Ceftriaxone, Cefepime, Ceftaroline
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- West Virginia University
Hypothyroidism, Thyroid Neoplasms
Study of Radioiodine (131-I) Uptake Following Administration of Thyrogen and Hypothyroid States During Thyroid Hormone Withdrawal.
Thyroid cancer is typically treated with surgery, radiation or a combination of both. Following surgical removal of thyroid tissue patients receive thyroid hormone replacement medication.
- Trial name
- NCT00001730
- Testing
- Thyrogen
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
mCIMT Effect Via Telerehabilitation
Effectiveness of Modified Constraint-Induced Movement Therapy Delivered Via Telerehabilitation in Children With Unilateral Cerebral Palsy: A Prospective Randomized Controlled Trial
Aim:In this prospective and randomized controlled thesis study; we aimed to compare Modified Constraint-Induced Movement Therapy (mCIMT) delivered via Telerehabilitation with the home program in children with Unilateral Cerebral…
- Trial name
- NCT07237490
- Testing
- mCIMT via Telerehabilitation, home exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University
Lymphedema of Upper Arm
Auto-Adjustable MOBIDERM® Autofit NIGHT-time Compression Armsleeve in the Upper Limb LYMphedema in Maintenance Phase
This study aims to assess Auto-Adjustable MOBIDERM® Autofit Armsleeve effect on upper limb volume excess after 3 months of maintenance phase treatment in patients with secondary upper limb lymphedema following breast cancer.
- Trial name
- LYMphoNIGHT (NCT04203069)
- Testing
- Control group : Day-time compression sleeve, Intervention group : Day-time compression sleeve and Night-time MOBIDERM® Autofit
- Where
- 8 sites in France, Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Thuasne
Primary Graft Dysfunction
Sodium Nitrite in Lung Transplant Patients to Minimize the Risk of Pulmonary Graft Dysfunction
This is a Phase 2 observational nonrandomized pilot investigation to evaluate the safety and efficacy of Sodium Nitrite administration for the reduction of Primary Graft Dysfunction (PGD) in patients undergoing lung transplant.
- Trial name
- NCT01715883
- Testing
- Sodium Nitrite
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Gladwin, Mark, MD
Pre Diabetes, Overweight and Obesity
TRE With Physical Activity for Weight Management
Approximately 24 million older adults have prediabetes. Obesity, age related decreases in lean mass and increases in fat mass, and sedentary lifestyle have been associated with functional and cognitive decline in older adults.
- Trial name
- NCT04978376
- Testing
- Time restricted eating
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Illinois at Chicago
Oral Surgical Procedure
Efficacy of Dexamethasone or Adrenaline in Inferior Alveolar Nerve Block
Oral and dental professionals were responsible for the discovery of anaesthesia, given their close day-to-day contact with pain and, hence, their motivation to seek the means to alleviate it.
- Trial name
- NCT04850885
- Testing
- inj dexamethasone 4mg/ml and inj lignocaine 20mg/ml
- Where
- Nepal
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University, Nepal
Airway Management
Self-Assembled Modified Macintosh Videolaryngoscope Versus McGrath Macintosh (MAC®) Videolaryngoscope: Which is Better?
Videolaryngoscopy highly improves success rate for endotracheal intubation in both normal and difficult airway. However, commercially available videolaryngoscope such as McGrath MAC® can be costly. The.
- Trial name
- NCT04850976
- Testing
- Endotracheal intubation
- Where
- Indonesia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Migraine Disorders
Management of Migraine Using Enerumab and Traditional Therapy at the Time of COVID-19
The objective of this study was to assess the efficacy of erenumab on frequency of monthly migraine days in adults at baseline, 3 months and 6 months, disability in patients with chronic migraine and on post covid migraine…
- Trial name
- NCT05052008
- Testing
- Erenumab
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Fayoum University
Respiratory Distress Syndrome, Adult, Ventilator-Induced Lung Injury
Long Term Follow up of Children Enrolled in the REDvent Study
This is a prospective observational follow-up study of children enrolled in a single center randomized controlled trial (REDvent).
- Conditions
- Respiratory Distress Syndrome, Adult, Ventilator-Induced Lung Injury, Neurocognitive Dysfunction, Quality of Life
- Trial name
- NCT03709199
- Testing
- Ventilation Inhomogeneity, Diaphragm Ultrasound, Respiratory Inductance Plethysmography
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Children's Hospital Los Angeles
Neonatal Respiratory Failure
Flow and Grow - The Ideal Time to Wean CPAP Off In Extremely Low Birth Weight Infants
Preterm neonates born at less than 30 weeks' gestation are commonly maintained on invasive or non-invasive respiratory support to facilitate gas exchange.
- Trial name
- Flow&Grow (NCT06123143)
- Testing
- Standardized/structured CPAP weaning protocol
- Where
- 5 sites in United States
- Volunteers
- 130 people
- Sponsor
- University of California, San Diego
Adverse Anesthesia Outcome
Prospective Comparison of Oral Intubation Via - Ambu® Aura Gain™ vs Slotted Guedel Tubus
The study has to show that an intubation with the AuraGain Laryngeal mask could bring the same benefits in terms of intubation in clinical practice, as the slotted Guedel tubus.
- Trial name
- NCT02570269
- Testing
- AuraGain, Slotted Guedeltubus
- Where
- Switzerland
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Degradation of Top2b and Top2a in Human by Dexrazoxane, Time Course and Degradation of Top2b in Human by Dexrazoxane
Prevention of Heart Failure Induced by Doxorubicin With Early Administration of Dexrazoxane
The purpose of this research study is to determine whether early administration of Dexrazoxane prevents Doxorubicin induced cardiotoxicity.
- Conditions
- Degradation of Top2b and Top2a in Human by Dexrazoxane, Time Course and Degradation of Top2b in Human by Dexrazoxane, Effects of Dexrazoxane on Healthy Human
- Trial name
- PHOENIX1 (NCT03930680)
- Testing
- Dexrazoxane
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Osteoporosis
A Study to Evaluate Efficacy and Safety of Denosumab for Prevention and Treatment of Osteoporosis in 1st Time Liver Transplant Recipients.
Organ transplant recipients are known to suffer from bone loss and subsequent fractures after the transplant operation with the most rapid bone loss occurring within the first 3-12 months.
- Trial name
- NCT04231682
- Testing
- Denosumab Injection
- Sponsor
- Albert Einstein Healthcare Network
Asthma
Single Dose Bronchodilatory Study in Asthma
Study to evaluate the bronchodilator effects of Zyflo CR in patients with chronic stable asthma.
- Trial name
- NCT01805687
- Testing
- Zileuton extended release
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Cornerstone Therapeutics Inc.