Clinical trials: Tic
Tourette Syndrome, Chronic Tic Disorder
Internet-based Behavior Therapy for Adults With Tourette Syndrome
This study protocol outlines a parallel-group, randomized controlled trial (RCT) designed to evaluate the effectiveness of Internet-delivered behavior therapy (BT) based on exposure with response prevention (ERP) for adults with…
- Trial name
- TICNET (NCT06271083)
- Testing
- Exposure with response prevention, Brief psychoeducation with general psychological support
- Where
- Sweden
- Volunteers
- 110 people
- Sponsor
- Karolinska Institutet
Tourette Syndrome, Tourette's Disorder
Assessment of Children With Tic Onset in the Past 6 Months
The purpose of this research is to study why most children who have tics never develop Tourette syndrome but some do. In other words, we aim to find features that may predict whose tics will go away and whose tics will continue…
- Conditions
- Tourette Syndrome, Tourette's Disorder, Chronic Motor or Vocal Tic Disorder, Transient Tic Disorder
- Trial name
- NewTics (NCT01177774)
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Washington University School of Medicine
Tourette Syndrome, Habit Reversal Training
Extinction Learning in Adults With Tourette Syndrome
Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but are still…
- Conditions
- Tourette Syndrome, Habit Reversal Training, Tic Disorders, Tics
- Trial name
- NCT04498364
- Testing
- Habit Reversal Training
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Tourette Syndrome, Tic Disorders
Median Nerve Stimulation Pilot
Results from the University of Nottingham suggested that rhythmic median nerve stimulation (MNS) improves tic symptoms in Tourette syndrome (TS).
- Conditions
- Tourette Syndrome, Tic Disorders, Tic Disorder, Chronic Motor or Vocal
- Trial name
- MNS (NCT04731714)
- Testing
- Rhythmic median nerve stimulation, Arrhythmic median nerve stimulation
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Washington University School of Medicine
Tourette Syndrome, Tic Disorder, Chronic Motor or Vocal
Open-label MNS for Tourette Syndrome
A recent report (Morera Maiquez et al 2020) described reduced tic severity in people with Tourette syndrome during 1-minute epochs of median nerve stimulation (MNS) at 10 Hz.
- Trial name
- NCT05016765
- Testing
- Active, self-directed electrical stimulation of the median nerve
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Washington University School of Medicine
Tourette Syndrome in Children, Tourette Syndrome in Adolescence
Extinction Learning in Youth With Tourette Syndrome
Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but have not been…
- Conditions
- Tourette Syndrome in Children, Tourette Syndrome in Adolescence, Habit Reversal Training, Tic
- Trial name
- NCT03765463
- Testing
- Habit Reversal Training
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Tic Disorder, Childhood
A Study of Prevalence and Clinical Characteristics of Tic Disorders in Children at Sohag University Hospital
Tics are brief, sudden, repetitive movements and/or sounds that increase with stress, anxiety, transitions, or excitement. Tics occur most commonly in children and adolescents, with boys more frequently affected than girls The…
- Trial name
- NCT05874765
- Testing
- Diagnostic and Statistical Manual of mental disorder- fifth edition ( DSM5)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Labor Pain, Labor Onset
The Effects of Breathing Exercises and Virtual Reality Applications During Pregnancy and Labor.
Aim and Objectives: The purpose of this study was to determine the effects of breathing exercises and virtual reality applications during pregnancy and labor on labor pain, duration, and birth satisfaction.
- Conditions
- Labor Pain, Labor Onset, Patient Satisfaction, Virtual Reality
- Trial name
- NCT05527236
- Testing
- Breathing Exercise, Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Semra Çevik, phD
Tourette Disorder, Tic Disorders
Evaluating the Efficacy and Safety of Yi-Gan San in Children and Adolescents With Tourette's Disorder
Yigansan was used in Ming dynasty by Xue Kai as a remedy for restlessness and agitation in children. We expect that the total YGTSS scores of Yigansan-treated subjects will be significantly reduced compared to that of…
- Trial name
- NCT03564132
- Testing
- Yigansan
- Where
- Taiwan
- Volunteers
- 38 people
- Sponsor
- China Medical University Hospital
Chronic Tic Disorder, Tourette Syndrome
Internet-based Cognitive Behavioral Therapy for Chronic Tic Disorder and Tourette's Disorder: a Feasibility Trial
Tic disorders, including Tourette's Disorder (TD) and Chronic Motor or Vocal Tic Disorder (CTD), are neurodevelopmental motor disorders characterised by motor and/or vocal tics.
- Trial name
- TICNET (NCT04908969)
- Testing
- Internet-delivered Cognitive Behavior Therapy for Chronic Tic Dosorder/Tourette Disorder
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Tourette's Disorder, Persistent (Chronic) Motor or Vocal Tic Disorder
Internet-delivered Behaviour Therapy for Children and Adolescents With Tourette's Disorder
The purpose of this trial is to evaluate the clinical efficacy, 12-month durability, and cost-effectiveness of BIP TIC - a therapist-guided and parent-guided internet-delivered behavioural intervention for children and…
- Trial name
- NCT03916055
- Testing
- Exposure and response prevention (ERP), Education on tics
- Where
- Sweden
- Volunteers
- 221 people
- Sponsor
- Karolinska Institutet
Tic Disorders, Tourette Syndrome
An Exploratory Study of Continuous Theta Burst Stimulation (cTBS) Based on fMRI in the Treatment of Tic Disorder
continuous theta burst stimulation (cTBS) is a safe and effective device for Gilles de la Tourette's syndrome treatment. GPi is an agreed curative target of deep brain stimulation.
- Trial name
- NCT04128397
- Testing
- traditional stimulation site continuous theta burst stimulation (cTBS), precise stimulation site cTBS
- Where
- 2 sites in China
- Volunteers
- 95 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Tic Disorder, Chronic Motor or Vocal, Tourette Syndrome in Children
Evaluation of a Cognitive Psychophysiological Treatment for Tourette Syndrome and Tic Disorders
It is a randomized controlled trial to compare two behavioural treatments, namely CBIT and CoPs. This study would be the first head-to-head randomized trial between two established treatments rather than supportive counseling or…
- Conditions
- Tic Disorder, Chronic Motor or Vocal, Tourette Syndrome in Children, Tourette Syndrome
- Trial name
- NCT03225430
- Testing
- Cognitive behavioural treatment for tics, Cognitive psychophysiological
- Where
- Canada
- Volunteers
- 144 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal
Tic Disorder, Childhood, Comorbidities and Coexisting Conditions
Improving Symptom Trajectories of Tic Disorders and Co-occurring Diagnoses: The Role of Integrative Intensive Intervention
The purpose to the current study was to examine the efficacy of a telehealth, group-based, combined and intensive intervention for youth with tic disorders (TDs) and common co-occurring diagnoses.
- Trial name
- NCT04878302
- Testing
- Combination of Comprehensive Behavioral Intervention for Tics (CBIT) and Evidence-based interventions for co-occurring diagnoses (i.e., Cognitive Behavioral Therapy, Behavioral Parent Training)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Florida International University
Tourette Syndrome, Chronic Tic Disorder
Proof of Concept Study of an Oral Orthotic to Reduce Tic Severity in Chronic Tic Disorder and Tourette Syndrome
The purpose of this study is to assess the feasibility of a trial on an oral orthotic for reducing tic severity in children ages 7-25 years with Tourette syndrome (TS) or Chronic Tic Disorder (CTD).
- Trial name
- NCT02067819
- Testing
- Active Oral Orthotic Treatment
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Weill Medical College of Cornell University
Tic Disorders
Neuromodulation of Inhibitory Control in Tic Disorders
The present study aims to assess the effects of non invasive electrical stimulation of the vagus nerve via transcutaneous vagus nerve stimulation (tVNS) on cognitive functions, inhibitory and tic control in patients with tic…
- Trial name
- NCT05263414
- Testing
- tVNS
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Tourette Syndrome, Chronic Tic Disorder
Anger Control Training for Youth With Tourette Syndrome
This is a clinical study of a cognitive-behavioral therapy known as anger control training in adolescents with Tourette Syndrome and explosive, disruptive behavior.
- Conditions
- Tourette Syndrome, Chronic Tic Disorder, Oppositional Defiant Disorder, ADHD
- Trial name
- NCT00486551
- Testing
- Anger control training
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Yale University
Tic Disorders
TICS: Transcranial Magnetic Stimulation for Intervening in Children With Tourette's Syndrome (CIHR)
Tourette's Syndrome (TS) is characterized by repetitive movements and vocalizations called tics. Due to the suffering caused by TS, children and adolescents often require treatment for their tics.
- Trial name
- TICS-CIHR (NCT03844919)
- Testing
- rTMS + CBIT
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Persistent Tic Disorders, Tourette Disorder
Online-Delivered Comprehensive Behavioral Intervention for Tics-Enhanced (CBIT-E)
The purpose of this pilot trial is to examine the preliminary efficacy of online-delivered Comprehensive Behavioral Intervention for Tics - Enhanced (CBIT-E).
- Trial name
- NCT05050734
- Testing
- Comprehensive Behavioral Intervention for Tics - Enhanced (CBIT-E)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Marquette University
Tourette's Disorder
Safety and Tolerability Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Disorder
The goal of the current trial is to obtain long term efficacy, safety and tolerability data of once weekly aripiprazole in children and adolescents with Tourette's Disorder.
- Trial name
- NCT01416441
- Testing
- Aripiprazole
- Where
- 80 sites in United States, Bulgaria and 8 more
- Volunteers
- 170 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.