Clinical trials: Tibial Shaft Fractures
Tibial Shaft Fractures
Primary Dynamization Versus Standard Interlocking Intramedullary Nail in Treatment of Tibial Shaft Fractures in Adults
fracture shfat tibia in adults treated by interlocking intramedullary nail by primary dynamic versus standard ways
- Trial name
- NCT06147219
- Testing
- interlocking intramedullary tibial nail
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Nonunion of Fracture of Tibia (Diagnosis)
Risk Factors for Post-Operative Nonunion of Tibial Shaft Fractures Based on a Path Analysis Model
Tibial shaft fractures is common long tubular fracture that account for about 13.7% of all fractures. And the incidence of nonunion of tibial shaft fracture varied from 1% to 80%.
- Trial name
- NCT03928912
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Low Ejection Fraction Patients, Fracture Tibia
Unilateral Epidural Block Versus Ultrasound Guided Combined Femoro-sciatic Nerves Block for Patients With Low Ejection Fraction
compare unilateral epidural anesthesia versus femoral/sciatic nerve block by ultrasound guided as anesthetic technique for cases with low ejection fraction undergoing insertion of nail tibia for fixation of fracture shaft tibia.
- Trial name
- NCT05506501
- Testing
- unilateral epidural anesthesia, Ultrasound guided femoro/ sciatic nerve block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Femoral Shaft Fracture, Tibial Shaft Fracture
MAGIK for Femoral/Tibial Shaft Fractures
The purpose of this phase 2 randomized control trial will be to evaluate the effect of glucose-insulin-potassium (GIK) therapy in the setting of lower extremity trauma to reduce short- and long-term muscle damage, acute…
- Trial name
- MAGIK (NCT05627479)
- Testing
- GIK solution, Isotonic Normal Saline Solution
- Where
- United States
- Sponsor
- NYU Langone Health
Trauma
Adjunctive Therapy to Treat Tibial Shaft Fractures
A phase 2, prospective, randomized, controlled, open-label (dose-blinded), parallel group, international multi-center study. The study will consist of four treatment groups - one control group (SoC) and three I-040202 groups…
- Trial name
- TSF (NCT00533793)
- Testing
- open fracture reduction
- Where
- 49 sites in Bulgaria, Czechia and 10 more
- Volunteers
- 201 people
- Sponsor
- Kuros Biosurgery AG
Tibia Fracture
Limb Injuries and Post Injury Rehabilitation Trials - Tibial Shaft Fracture
Aim of our study is to compare immediate full weight-bearing and partial weight-bearing for 6 weeks after a tibial shaft fracture treated with intramedullary nailing.
- Trial name
- LIMPER-TSF (NCT05151926)
- Testing
- Full weight-bearing, Partial weight-bearing, Intramedullary nailing
- Where
- 3 sites in Finland
- Volunteers
- 240 people
- Sponsor
- Tampere University Hospital
Tibial Fracture, Fracture of the Tibia Type AO/OTA 42
Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures
Approximately 1000 patients presenting with tibial shaft fractures (AO type 42) will be enrolled prospectively in this registry.
- Trial name
- FROST (NCT03598530)
- Testing
- Surgery
- Where
- 15 sites in United States, Belgium and 7 more
- Volunteers
- 1,000 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Closed Transverse Fracture of Shaft of Tibia
Union Rate of Transverse Tibia Fracture
The investigators will compare the three methods of seating a tibial nail - Backslapping or Backslapping with Dynamic Locking or Internal Compression.
- Trial name
- NCT03042533
- Testing
- Conventional Compression, Standard Backslapping, Dynamic Locking with Backslapping
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Washington
Tibial Shaft Fracture
Intramedullary Nailing vs External Ring Fixation for the Treatment of Tibial Shaft Fractures
This study is a multicenter pragmatic assessor blinded randomized and prospective clinical trial in which standard intramedullary nailing is compared with external ring fixator for patients with tibial shaft fractures.
- Trial name
- IMVEX (NCT03945669)
- Testing
- Intramedullary Nailing, External Ring fixation
- Where
- 3 sites in Denmark
- Volunteers
- 67 people
- Sponsor
- Aalborg University Hospital
Femoral Neck Fractures, Intertrochanteric Fractures
Opioid-Free Pain Treatment in Trauma Patients
Analgesic drug study that will compare pain outcomes of opioid analgesia and opioid-free analgesia in post-operative orthopedic patients.
- Conditions
- Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture
- Trial name
- NCT06078371
- Testing
- Opioid-free pain treatment
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Kansas Medical Center
Tibial Fractures
ACTiF- Assessment of Closed Tibial Fractures
The purpose of this study is to find out the good and bad effects of an investigational drug called CP-533,536 in patients with closed fracture of the tibial shaft undergoing internal fixation using reamed inter-locked IM nailing…
- Trial name
- NCT00533377
- Testing
- CP-533, 536, Standard of Care, CP-533,536
- Where
- 56 sites in United States, Australia and 9 more
- Volunteers
- 276 people
- Sponsor
- Pfizer
Tibial Fractures, Nonunion of Fracture
Intramedullary Bone Grafting for Open Tibial Shaft Fractures
This study will examine if there is a difference between the time to full union between the control group and the study group. Each group will be composed of patients who have an open fracture in the mid tibia.
- Conditions
- Tibial Fractures, Nonunion of Fracture, Delayed Union of Fracture
- Trial name
- NCT03891888
- Testing
- Intramedullary Bone Graft
- Where
- 2 sites in United States
- Volunteers
- 130 people
- Sponsor
- University of Louisville
Tibial Shaft Fractures in Children
Study of Tibial Shaft Fractures in Children
Tibial shaft fracture is one of the most common fractures in children and adolescents. It encompasses approximately 15 % of all long-bone fractures and is third behind only fractures of the femur and both bones of the forearm.
- Trial name
- NCT01238523
- Testing
- Long leg cast in full extension, Long leg cast with 45 degrees of flexion
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of California, Los Angeles
Proximal Tibia Fracture, Tibial Shaft Fracture
MY01 Pressure Monitoring in Adolescent Tibia Fractures
The goal of this clinical trial is to learn more about anterior leg compartment pressures in adolescents who have sustained tibia fractures.
- Conditions
- Proximal Tibia Fracture, Tibial Shaft Fracture, Acute Compartment Syndrome
- Trial name
- NCT07674043
- Testing
- Continuous Compartmental Pressure Monitor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
Proximal Third Tibial Shaft Fractures in Children
Results of Retrograde Titanium Elastic Nails for Fixation of Proximal Third Tibial Shaft Fractures in Children.
Pediatric tibial shaft fracture is the third most common pediatric long bone fracture after fracture of femur and forearm, representing 15% of all pediatric fractures.
- Trial name
- NCT06500325
- Testing
- retrograde titanium elastic nails for fixation of proximal third tibial shaft fractures in children
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Broken Leg
Tibial Shaft Nailing Treated With Suprapatellar Nailing
The goal of this project is to determine the incidence of intra-articular knee pathology following tibial shaft fractures as evaluated by intraoperative knee aspiration and physical exam, and to evaluate for chondral injuries…
- Trial name
- NCT02510339
- Testing
- Observation
- Volunteers
- 16 people
- Sponsor
- Orlando Health, Inc.
Broken Leg
Suprapatellar Nailing of Tibial Shaft Fractures
To investigate the functional outcomes and prevalence and severity of knee pain for patients undergoing suprapatellar nailing of tibial shaft fractures.
- Trial name
- NCT02728362
- Volunteers
- 38 people
- Sponsor
- Corewell Health West
Tibia Fracture, Knee Pain Chronic
Knee Pain After Intramedullary Nailing in the Tibia
The primary objective of this study is to evaluate the long-term outcome after inserting an intramedullary nail in patients with a tibial shaft fracture using an injury-specific questionnaire.
- Trial name
- NCT03649360
- Where
- Denmark
- Volunteers
- 223 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Anterior Knee Pain, Patellar Tendon Disorder
Anterior Knee Pain and Patellar Tendon Elasticity After Infrapatellar Tendon-Split Tibial Intramedullary Nailing
This prospective single-center observational cohort study will evaluate the relationship between anterior knee pain and patellar tendon elasticity after infrapatellar tendon-split tibial intramedullary nailing.
- Conditions
- Anterior Knee Pain, Patellar Tendon Disorder, Tibial Shaft Fractures
- Trial name
- NCT07659899
- Testing
- Infrapatellar tendon-split tibial intramedullary nailing, Shear-wave ultrasound elastography
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bagcilar Training and Research Hospital
Tibial Fractures, Surgery
Clinical Validation of the C-Arm Rotational View (CARV) to Avoid Rotational Malalignment After Intramedullary Nailing of Tibial Shaft Fractures.
Tibia shaft fractures are common long bone fractures in the field of Orthopaedic Trauma. In the USA, a total of 492.000 tibial fractures were reported per year by the National Center of Health Statistics (NCHS).
- Conditions
- Tibial Fractures, Surgery, Complication,Postoperative
- Trial name
- NCT05459038
- Testing
- C-Arm Rotational View (CARV)
- Where
- 2 sites in Australia, Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen