Clinical trials: Thyroid Dysfunction
Hypocalcemia, Thyroid
Is Correcting Total Serum Calcium Levels Important After Thyroidectomy
This study is designed as a prospective non-randomized longitudinal single- center cohort study to evaluate the importance of correcting total serum calcium levels.
- Conditions
- Hypocalcemia, Thyroid, Parathyroid Dysfunction, Calcium Disorder
- Trial name
- NCT04304573
- Testing
- Total serum calcium blood test
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- University Hospital Sestre Milosrdnice
Type 2 Diabetes Mellitus (T2DM), Thyroid Dysfunction
Relationship Between Thyroid Dysfunction and Diabetes
Evaluate the expression of glycemic parameters, lipid profile, and thyroid hormones in patients with type 2 diabetes mellitus in upper egypt.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Thyroid Dysfunction, Metabolic Syndrome, Upper Egypt Patients
- Trial name
- NCT07099937
- Testing
- Observational cross-sectional study with no intervention.
- Volunteers
- 120 people
- Sponsor
- Assiut University
Hypothyroidism, Pregnancy Related
Normal Range of TSH and FT4 in Pregnancy
Physiological changes necessitate the use of pregnancy-specific reference ranges for thyrotrophin (TSH) and free T4 (FT4) to diagnose thyroid dysfunction during pregnancy.
- Conditions
- Hypothyroidism, Pregnancy Related, Thyroid, Dysfunction
- Trial name
- NRTSHTURKEY (NCT04860622)
- Testing
- Serum thyroid function tests
- Where
- Turkey (Türkiye)
- Volunteers
- 528 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Excessive Iodine Status, Thyroid Dysfunction, Antepartum
Research on Excessive Iodine Status in Pregnancy
To explore main cause and health impact of iodine excess during pregnancy, we performed iodine evaluation for 390 consecutive pregnant women from January 1st, 2016 to December 31st, 2016.
- Conditions
- Excessive Iodine Status, Thyroid Dysfunction, Antepartum, Pregnancy Related, Neonatal Disorder
- Trial name
- NCT03422406
- Testing
- Dietary iodine intake restriction
- Volunteers
- 18 people
- Sponsor
- Peking Union Medical College Hospital
Hypocalcemia, Thyroid
Is There Benefit From Early Postoperative PTH Monitoring?
This study is designed as a prospective non-randomized longitudinal single-center cohort study. It will enroll around 120 patients undergoing total thyroidectomy with data being collected from September 2019 up to December 2019.
- Conditions
- Hypocalcemia, Thyroid, Postoperative Complications, Parathyroid Dysfunction
- Trial name
- NCT04160637
- Testing
- Immediate postoperative PTH serum sampling and cut-off value identification
- Where
- Croatia
- Volunteers
- 120 people
- Sponsor
- University Hospital Sestre Milosrdnice
Hyperprolactinemia, Thyroid Dysfunction
Develop and Implement Methods for Diagnostic and Treatment of Hormonal Disorders in Patients With Chronic Kidney Disease
Methods of diagnostic and treatment of hormonal disorders in patients with chronic kidney disease (CKD) will be developed and implemented in real clinical practice.
- Conditions
- Hyperprolactinemia, Thyroid Dysfunction, Bone Diseases, Metabolic, Chronic Kidney Diseases
- Trial name
- NCT04439747
- Testing
- Ultrasound, DXA, hormonal tests
- Where
- Belarus
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Belarusian State Medical University
Diabete Mellitus, Hypogonadism
Hypothalamic-pituitary Dysfunction in Diabetes
Type 2 Diabetes mellitus (T2DM) is a chronic disease with a high prevalence and several comorbidities impacting on public health and society.
- Conditions
- Diabete Mellitus, Hypogonadism, Hypogonadotropic Hypogonadism, Hypergonadotropic Hypogonadism
- Trial name
- DIAPO (NCT05752591)
- Testing
- Diagnostic testing
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Auxologico Italiano
Hepatic Encephalopathy, Hepatic Impairment
Throid Dysfunction in Liver Failure and Its Eddects Upon Outcome
Liver plays an important role in the metabolism of thyroid hormones, as it is the most important organ in the peripheral conversion of tetraiodothyronine (T4) to triiodothyronine (T3) by Type 1 deiodinase.
- Conditions
- Hepatic Encephalopathy, Hepatic Impairment, Hypothyroidism, Hepatic Failure
- Trial name
- NCT06179368
- Testing
- hypothroidism, euothyroid
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Dialysis; Complications
Assessment of Thyroid Dysfunction in Patients Undergoing Haemodialysis at Sohag University Hospital
Thyroid dysfunction is a prevalent endocrine disorder that significantly impacts the health of patients with chronic kidney disease (CKD), particularly those undergoing dialysis.
- Trial name
- NCT07022236
- Testing
- Thyroid profile
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Sohag University
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Thyroid, Carotid Doppler
Effect of Head Position During Thyroidectomy on Postoperative Cognitive Functions
The aim of our study is to observe the effect of head-neck position of patients scheduled for thyroidectomy, on carotid artery blood flow, regional cerebral oxygen saturation measured using near-infrared spectroscopy technology…
- Conditions
- Thyroid, Carotid Doppler, Cerebral Perfusion
- Trial name
- NCT04830293
- Testing
- Carotis Doppler Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Thyrotoxicosis, Hypothyroidism
Biosignals by Wearables in Thyroid Dysfunction
This study is a single center observational study to investigate the association between biosignals from wearables and thyroid dysfunction.
- Trial name
- NCT04806269
- Testing
- Fitbit and Glandy
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Hyperthyroidism, Graves Disease
Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosis
During July 2019 to August 2020, a single-blind clinical trial was done to 36 patients with Graves' disease. At the beginning of the study, subjects were accommodated into 2 groups, 17 into PTU groups and 19 into methimazole…
- Conditions
- Hyperthyroidism, Graves Disease, Atherosclerosis of Artery, Pathophysiology
- Trial name
- NCT05118542
- Testing
- Propylthiouracil, Methimazole
- Where
- Indonesia
- Volunteers
- 36 people
- Sponsor
- Universitas Indonesia
Subclinical Hypothyroidism, Autoimmune Thyroid Disease
NeoThyr - the Role of Mitochondria-dysfunction in Newborns of Mothers With Autoimmune Thyroid Disease
Previously, studies have shown that children of women with thyroid autoantibodies experience more birth complications and poorer health in their first days.
- Conditions
- Subclinical Hypothyroidism, Autoimmune Thyroid Disease, Alteration of Mitochondrial Membrane
- Trial name
- NCT02061111
- Where
- Denmark
- Volunteers
- 77 people
- Sponsor
- Naestved Hospital
Thyroid Nodule, Thyroid Cancer
Cognition and QoL After Thyroid Surgery
The development of cognitive dysfunction can profoundly affect HR-QoL as well as the possibility of societal participation and ability to work, and thereby relevantly impacts prospects for cancer survivorship.
- Conditions
- Thyroid Nodule, Thyroid Cancer, Cognitive Decline, Survivorship
- Trial name
- NCT05088187
- Where
- Sweden
- Volunteers
- 320 people
- Sponsor
- Karolinska University Hospital
Postoperative; Dysfunction Following Cardiac Surgery
Oral Triiodothyronine for Children Undergoing Cardiopulmonary Bypass in Indonesia
A condition of decreased serum T3 level in children after cardiac surgery using cardiopulmonary bypass has been commonly recognized as euthyroid sick syndrome (ESS).
- Trial name
- OTICC (NCT02521168)
- Testing
- Oral triiodothyronine
- Where
- Indonesia
- Volunteers
- 177 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Hypopituitarism, Hypogonadism
Detection and Treatment of Endocrine Abnormalities in Childhood Cancer Survivors and Hematopoietic Stem Cell Transplant Recipients
This study will determine the prevalence of endocrine-related side effects in children who have been treated for cancer and establish a database and registry organized according to cancer diagnosis, treatments and endocrine side…
- Conditions
- Hypopituitarism, Hypogonadism, Thyroid Dysfunction, Bone Diseases, Metabolic
- Trial name
- NCT00504218
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Thyroid Dysfunction
Serum Thyroid Function After Iodinated Contrast Administration
This study investigated the changes in serum thyroid function and urinary iodine levels before and after the use of iodinated contrast to analyze the prevalence of thyroid dysfunction in the Chinese euthyroid adults after using…
- Trial name
- NCT05786846
- Testing
- Iodinated contrast agents
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Thyroid Dysfunction
Frequency of Florid Hyperthyroidism In Patients Taking Iodinated Salt
Thyroxin a vital hormone for life lot of body functions depend on proper functioning on pituitary thyroid axis. it exists in two major forms Thyroxine (T4) and (T3) , each of them containing two iodine atoms on their inner…
- Trial name
- I2 and thyroid (NCT04809454)
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan