Clinical trials: Thyroid Dysfunction
Non Small Cell Lung Cancer Metastatic, Treatment Adverse Effect
Thyroid Dysfunction and Nivolumab Reponse in NSCLC
This is an observational, retrospective and monocentric study, conducted at the university Hospital of Brest The primary objective is to assess the association between the occurrence of thyroid dysfunction in patients treated…
- Conditions
- Non Small Cell Lung Cancer Metastatic, Treatment Adverse Effect, Thyroid Dysfunction, Immune Checkpoint Inhibitor
- Trial name
- THYRONIVO (NCT04470440)
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Brest
Infertility, Female
Prevalence of Thyroid Dysfunction and Anti-thyroid Antibodies in Infertile Women
The study population will be divided into three groups: Group (A) consisting of 40 infertile women with either unexplained or anovulatory infertility with/without associated male factor of infertility, Group (B) consisting of 40…
- Trial name
- NCT03964779
- Testing
- Hormonal assay, Antibody assay
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Thyroid; Functional Disturbance
Eltroxin Administration to Patients With Extremely Low T4 Values in the Intensive Care Unit
Nonthyroidal illness (formerly called sick euthyroid syndrome) is a common condition in patients hospitalized in the intensive care unit, and it is caused by changes in the levels of thyroid hormones in the blood .
- Trial name
- NCT06154382
- Testing
- Eltroxin administration
- Where
- Israel
- Volunteers
- 350 people
- Sponsor
- Meir Medical Center
Overt, Sub-clinical
Association Between Overt and Sub-clinical Primary Hypothyroidism and Metabolic Dysfunction-Associated Steatoic Liver Disease in Non-Diabetic Patients
This study aims to estimate the prevalence of Metabolic dysfunction - associated Steatoic liver disease (MASLD) among adults with primary hypothyroidism (overt or sub-clinical 1ry hypothyroidism) and prevalence of MASLD in…
- Conditions
- Overt, Sub-clinical, Primary Hypothyroidism, Metabolic Dysfunction-Associated Steatoic Liver Disease
- Trial name
- NCT07603817
- Testing
- FibroScan, Thyroid Function Assessment
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Thyroid Dysfunction
Iontophoresis With Potassium Iodide and Thyroid Function
The aim of the study: To assess the influence of iontophoresis treatment with 2% potassium iodide on the level of thyroid hormones (TSH, FT3, FT4) The study group: conducting 10 iontophoresis treatments with Potassium iodide; The…
- Trial name
- NCT04013308
- Testing
- Iontophoresis with 2% potassium iodide
- Where
- Poland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Rzeszow
Thyroid Dysfunction, Acute Illness
Thyroid Profiles in Patients With Acute Illness
Patients admitted to the hospital with acute illness may have a wide spectrum of thyroid function abnormalities. It is largely unknown whether such aberrations are temporary or persist for a long time, and whether they impact…
- Trial name
- NCT05980923
- Testing
- Performing blood thyroid test (TSH, FT4, FT3)
- Where
- Jordan
- Sponsor
- Jordan Collaborating Cardiology Group
Postoperative; Dysfunction Following Cardiac Surgery
Oral Triiodothyronine for Infants Less Than 5 Months & Malnourished Children Undergoing Cardiopulmonary Bypass in Indonesia
Infants and children undergoing cardiac surgery require mechanical support for circulation called cardiopulmonary bypass. The artificial pump ensures that blood flow to the body is maintained during surgical procedure on the…
- Trial name
- I-TRICC (NCT02222532)
- Testing
- Tetronine
- Where
- Indonesia
- Volunteers
- 224 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Thyroid, Gland; Functional Disturbance
Ultrasound and Functional Thyroid Evaluation
Thyroid disorders are most commonly concomitant with prematurity and still remains a controversial topic. The incidence of a temporary form of hypothyroidism among preterm neonates is higher than in the general population.
- Trial name
- NCT04208503
- Testing
- thyroid ultrasound
- Where
- 2 sites in Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Cognitive Impairment
Cognitive Functions During Thyrotropin Suppressive Therapy in Patients With Differentiated Thyroid Carcinoma
Thyroid carcinoma is the common endocrine system malignant neoplasm. At present it has become the malignant neoplasm of fastest growing incidence rate. More than 90% thyroid carcinoma is thyroid differentiated carcinoma（DTC）.
- Trial name
- NCT02665325
- Testing
- TSH-suppressive therapy
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Inner Mongolia Medical University
Keratoconus in Thyroid Gland Dysfunction
Prevalence Of Keratoconus Among Patients With Thyroid Gland Dysfunction
Hormonal imbalances are likely to affect the corneal metabolism and may be also associated with Keratoconus. Among the various endocrinologic dysfunctions assumed so far, thyroid gland dysfunction (TGD) (hypo- or hyperthyroidism…
- Trial name
- NCT04346992
- Testing
- no intervention
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Fayoum University
Chronic Kidney Disease, Thyroid Dysfunction
Evaluation of Thyroid Function in Patients With Chronic Kidney Disease
A higher prevalence of thyroid disease has been associated with chronic kidney disease (CKD), and subclinical hypothyroidism seems to be the most common dysfunction.
- Trial name
- NCT04658524
- Testing
- Thyroid function
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Rio de Janeiro State University
Cardiovascular Diseases, Heart Diseases
Subclinical Thyroid Dysfunction and Risk of Myocardial Infarction and Stroke
To examine the association of subclinical hypothyroidism and risk of myocardial infarction and stroke in a large prospective cohort of post-menopausal women.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypothyroidism, Myocardial Infarction
- Trial name
- NCT00094237
- Volunteers
- 3,200 people
- Sponsor
- University of North Carolina, Chapel Hill
Thyroid Dysfunction
Prevalence and Prognostic Effects of Thyroid Abnormalities in Patients With Acute Coronary Syndrome.
The goal of this observational study is knowledge of Prevalence of throid abnormalities in patients with acute coronary syndrome And prognostic effects of thyroid abnormalities in patients with acute coronary syndrome as early…
- Trial name
- NCT06579014
- Volunteers
- 129 people
- Sponsor
- Assiut University
CKD
Thyroid Dysfunction and Dyslipidemia in Patients With Chronic Kidney Diseases
Early diagnosis of thyroid and lipid disorders by regular screening, and treatment of such disorders in CKD patients may be highly beneficial to slow progression of CKD.
- Trial name
- NCT03277911
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ocular Motility Disorders, Strabismus
Clinical Validation of AI-Based Quantitative Eye Movement Analysis From Smartphone 9-Gaze Videos (Glandy EOM)
This prospective, multicenter, multinational observational study evaluates the clinical validity of an AI-based quantitative eye movement analysis system (Glandy EOM) that analyzes smartphone-recorded 9-gaze videos.
- Conditions
- Ocular Motility Disorders, Strabismus, Extraocular Muscle Dysfunction, Thyroid Eye Disease
- Trial name
- GLANDY-EOM-VAL (NCT07623837)
- Testing
- Glandy EOM (AI-based quantitative eye movement analysis software)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- THYROSCOPE INC.
Thyroid Dysfunction, Diabetes Mellitus
Maternal Endocrine System and Metabolic Diseases and Offspring Health: Prediction Within a Birth Cohort
The incidence of metabolic diseases in pregnant women is increasing rapidly, and the risk of metabolic diseases in children is also increasing.
- Trial name
- NCT05952739
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Thyroid Disease
Effect of Nutrition Education on the Quality of Life, Chronic Disease Adaptation in Patients With Thyroid Dysfunction
This thesis study is designed to examine the effects of nutrition education provided to individuals with thyroid dysfunction on their quality of life and adaptation to the disease.
- Trial name
- NCT07027579
- Testing
- Nutrineal
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Çanakkale Onsekiz Mart University
Thyroid Cancer
Salivary dysfuncTion After Radioiodine Treatment
Aim/Introduction: The treatment of differentiated thyroid cancer includes generally a total thyroidectomy, followed by a radioiodine (131I)-therapy.
- Trial name
- START (NCT04876287)
- Testing
- Radioiodine
- Where
- France
- Volunteers
- 138 people
- Sponsor
- French Nuclear Safety and Radiation Protection Authority (ASNR)
Thyroid Dysfunction, Mental Fatigue
Effect of Thyroid Hormone Replacement on Fatigability in Untreated Older Adults With Subclinical Hypothyroidism
Thyroid hormone is a key regulatory hormone for a range of physiological systems. An impaired function of the thyroid gland such as subclinical hypothyroidism (SCH) can affect quality of life.
- Conditions
- Thyroid Dysfunction, Mental Fatigue, Fatigue
- Trial name
- TRUST FATIGUE (NCT02500342)
- Testing
- Levothyroxine
- Where
- 3 sites in Ireland, Switzerland
- Volunteers
- 276 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern