Clinical trials: Thrombus
Pulmonary Embolism
Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)
This is a prospective, multi-center, pivotal study to demonstrate the safety and effectiveness of the Laguna Thrombectomy System for the treatment of pulmonary embolism.
- Trial name
- TRUST (NCT06041594)
- Testing
- Laguna Thrombectomy System
- Where
- 21 sites in United States, Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Innova Vascular, Inc.
Portal Vein Thrombosis
Efficacy and Safety of Rivaroxaban in the Management of Acute Non-neoplastic PVT Compensated Cirrhosis
-Rivaroxaban is factor Xa inhibitor
- Trial name
- NCT03193502
- Testing
- rivaroxaban
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sherief Abd-Elsalam
Left Ventricular Assist Device, Heart Failure
Pulse Wave Analysis in Advanced Heart Failure
A comparison of pulse wave characteristics, as measured by peripheral tonometry, in pre and post Left Ventricular Assist Device (LVAD) patients.
- Conditions
- Left Ventricular Assist Device, Heart Failure, Intra-aortic Balloon Pump, LVAD Clot
- Trial name
- PWA-HF (NCT01642927)
- Where
- United States
- Sponsor
- University of Minnesota
Large Vessel Occlusion, Acute Ischemic Stroke
Intracranial Thrombosis Aspiration Catheter for Recanalization in Acute Ischemic Stroke Therapy (RECOVER)
This study is a prospective, multi-center, open-label, end-point blinded, randomized, parallel positive control, non-inferiority clinical trial, with a purpose to evaluate the safety and efficacy of Hemo Jirui intracranial…
- Conditions
- Large Vessel Occlusion, Acute Ischemic Stroke, Cerebrovascular Disorders
- Trial name
- NCT03753061
- Testing
- Aspiration Catheter, Solitaire FR
- Where
- 23 sites in China
- Volunteers
- 204 people
- Sponsor
- Ministry of Science and Technology of the People´s Republic of China
Acute Coronary Syndrome, Coronary Artery Disease
Effect of Pretreatment With Ticagrelor on Residual Thrombus After PCI in Patients Presenting With ACS in Comparison With Delayed Treatment at the Time of PCI: an OCT Study
Subjects presenting with probable acute coronary syndromes scheduled for cardiac catheterization will be enrolled in this study.
- Trial name
- NCT01916902
- Testing
- Ticagrelor- Delayed Administration, Ticagrelor- Immediate Administration, Optical Coherence Tomography
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Thrombosis
Pharmacokinetic and Metabolism of [14^C] BMS-986177 in Healthy Male Participants
This is an ADME study. Human radiolabeled mass balance studies are performed as part of drug development to obtain information about the absorption, distribution, metabolism, and excretion (ADME) of a study treatment.
- Trial name
- NCT03939702
- Testing
- BMS-986177
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Circadian Variation in Anti-Factor Xa (Anti-FXa) Activity
Circadian Variation of Anti-Factor Xa in Hospitalized Trauma Patients
The purpose of this study is to determine whether a circadian rhythm exists in anti-FXa levels and AT3 activity in hospitalized trauma patients receiving low-molecular-weight heparin (LMWH) chemoprophylaxis
- Trial name
- NCT07856641
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pregnancies
Preterm Delivery Prevention in Twins With Progesterone
Twin pregnancies have very high preterm delivery rate. Until now, no RCT has proven benefit of progesterone in this population. In contrast, singleton pregnancies are treated with this hormone.
- Trial name
- NCT01927029
- Testing
- Progesterone
- Volunteers
- 213 people
- Sponsor
- Universidad del Desarrollo
Aorta Aneurysm
Graft Thrombosis After Endovascular Aortic Repair - a Single Center Experience With the Cook Zenith Alpha Spiral-Z®
The purpose of this study is to assess the extent of thrombosis in the Zenith Alpha Spiral-Z® stent graft.
- Trial name
- NCT04564560
- Testing
- Endovascular aortic repair with Zenith Alpha Spiral-Z®
- Where
- Norway
- Volunteers
- 161 people
- Sponsor
- St. Olavs Hospital
Central Venous Catheter Thrombosis, Central Venous Catheter Related Bloodstream Infection
Central Venous Catheter-related Complications in Patients Under Anticancer Treatment
Oncology and hemotology patients under anticancer treatments are exposed to increased risks of central venous catheter-related complications due to the underlying cancer and its treament.
- Conditions
- Central Venous Catheter Thrombosis, Central Venous Catheter Related Bloodstream Infection, Solid Tumor, Hematologic Malignancy
- Trial name
- KTcCHO (NCT05455866)
- Testing
- central venous catheter
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Alpes Leman
Pulmonary Embolism
Effect of Climatic Factors on the Seasonal Fluctuation of Pulmonary Embolism
To estimate the risks of daily hospital admissions for pulmonary embolism associated with short term exposure to climatic factors (temperature, precipitation, air pressure, sunshine duration, relative humidity, wind speed, and…
- Trial name
- NCT04419194
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Peking Union Medical College Hospital
Deep Venous Thrombosis, Upper Extremity Deep Venous Thrombosis
Apixaban for Routine Management of Upper Extremity Deep Venous Thrombosis
This study will assess the safety and effectiveness of a drug called apixaban for the treatment of upper extremity deep vein thrombosis (UEDVT) and clinically important bleeding.
- Conditions
- Deep Venous Thrombosis, Upper Extremity Deep Venous Thrombosis, Thrombus, Venous Thromboembolism
- Trial name
- ARM-DVT (NCT02945280)
- Testing
- apixaban
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Intermountain Health Care, Inc.
Venous Thrombosis, Pulmonary Embolism
Two Weeks of Low Molecular Weight Heparin for Distal Vein Thrombosis
The purpose of this study is to determine whether a limited duration of treatment (two weeks of low molecular weight treatment) is a safe and effective treatment for distal deep vein thrombosis of the lower limb.
- Trial name
- TWISTER (NCT01252420)
- Testing
- Enoxaparin
- Where
- 4 sites in Australia, New Zealand
- Volunteers
- 330 people
- Sponsor
- Monash Medical Centre
Coronary Artery Disease
DESTINY TRIAL (Inspiron x Biomatrix)
The main objective of this study is to evaluate the effectiveness of stent Inspiron ™ sirolimus-eluting and coating the abluminal biodegradable stent Biomatrix Flex ™ lesions in native coronary arteries.
- Trial name
- NCT01856088
- Testing
- Inspiron Stent, Biomatrix Flex Stent
- Where
- 10 sites in Brazil
- Volunteers
- 170 people
- Sponsor
- Scitech Produtos Medicos SA
Cerebral Venous Thrombosis
Comparison of the Efficacy of Rivroxaban to Coumadin( Warfarin ) in Cerebral Venous Thrombosis
In past few years new anticoagulants have been developed which directly inhibit thrombin or factor X.factor x inhibitor is available in Pakistan.
- Trial name
- CVT (NCT03191305)
- Testing
- Coumadin, Rivoroxaban
- Volunteers
- 50 people
- Sponsor
- Foundation University Islamabad
Thrombocythemia Essential
Prospective Study of Different Biological Tests (Multiplate, ROTEM) in a Cohort of Patients Followed for Essential Thrombocytemia (ET)
There is no prospective study published on the Essential Thrombocythemia and the correlation between this specific disease, its complications and the biological variations observed.
- Trial name
- THETE (NCT03212053)
- Testing
- biological tests of haemostasis at each consultation (Multiplate, ROTEM, VASP)
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Hospices Civils de Lyon
Venous Thrombosis
Ongoing Registry of Deep Venous Reconstructions
Ongoing registration of deep venous obstructive disease patients treated by means of percutaneous transluminal angioplasty (PTA) and stenting with or without endophlebectomy (surgical desobstruction, also termed endovenectomy) of…
- Trial name
- NCT02650453
- Testing
- Deep venous reconstruction
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Maastricht University Medical Center
Atrial Fibrillation, Embolism
Oral Anticoagulation and Self-management
An intervention program targeting patients and caregivers based on education about their condition and training in the use of portable coagulomenter to self monitor and training on the treatment adjustment to self manage, can be…
- Trial name
- NCT01878539
- Testing
- coagulometer, training programme
- Where
- Spain
- Volunteers
- 333 people
- Sponsor
- Osakidetza
Venous Thromboembolism, Deep-Vein Thrombosis
Pro-coagulant Markers and Anticoagulant Failure in Cancer Patients at Risk for Recurrence of Venous Thromboembolism
The presence of clots in the veins of arms and/or legs or lungs of Cancer patients decreases their quality of life, delays their treatment and may cause death.
- Conditions
- Venous Thromboembolism, Deep-Vein Thrombosis, Pulmonary Embolism, Cancer
- Trial name
- REMARK (NCT01602445)
- Where
- 5 sites in Canada
- Volunteers
- 700 people
- Sponsor
- Ottawa Hospital Research Institute
Cerebral Venous Thrombosis, Anticoagulants and Thrombotic Disorders
Safety and Efficacy of Edoxaban and Rivaroxaban to Cerebral Venous Thrombosis in Chinese Patients
The goal of this observational study is to learn the safety and efficacy of edoxaban and rivaroxaban in Chinese population with the age range from 18 to 80 years who take edoxaban or rivaroxaban to treat their cerebral venous…
- Conditions
- Cerebral Venous Thrombosis, Anticoagulants and Thrombotic Disorders, Anticoagulation Treatment, Anticoagulant Therapy
- Trial name
- NCT06947707
- Where
- China
- Volunteers
- 1,486 people
- Sponsor
- Xuanwu Hospital, Beijing