Clinical trials: Thoracotomy
Ketamine, Levobupivacaine
Adding Ketamine to Levobupivacaine in Paravertebral Block in Thoracotomy
To evaluate the role of adding ketamine to levobupivacaine in PVB on acute and chronic pain in thoracotomy
- Conditions
- Ketamine, Levobupivacaine, Paravertebral Block, Acute Pain
- Trial name
- NCT06011746
- Testing
- Ketamine + Levobupivacaine, Levobupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Acute Post-thoracotomy Pain
Peri-neural Dexmedetomidine as an Adjuvant to Bupivacaine Induced Paravertebral Block in Patients Undergonig Thoracotomy
This study evaluates the effect of adding dexmedetomidine as an adjuvant to bupivacaine in patients undergoing thoracotomy when administered peri-neurally in thoracic paravertebral space.
- Trial name
- NCT02397603
- Testing
- dexmedetomidine bupivacaine, Bupivacaine saline
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Lung Cancer, Thoracic Cancer
Exploring Robotic-assisted Thoracic Surgery for Lung Cancer
Background Surgery for lung cancer can be performed using open (thoracotomy) or minimally invasive techniques (Video Assisted Thoracic Surgery (VATS)).
- Conditions
- Lung Cancer, Thoracic Cancer, Surgery
- Trial name
- ROSE (NCT03658083)
- Testing
- Thoracotomy, Robotic-assisted thoracic surgery
- Where
- 2 sites in United Kingdom
- Volunteers
- 55 people
- Sponsor
- Teesside University
Pain
Comparison of the Clinical Efficacy of 2 Paravertebral Block Strategies in Thoracic Surgery by Thoracotomy: by the Anesthetist (Paravertebral Block Guided by Ultrasound) and by the Thoracic Surgeon (Paravertebral Block Visual)
Post-thoracotomy pain is one of the most severe. The local analgesia allows its effective control and a reduction of postoperative morbidity and mortality. The gold standard for local analgesia is the thoracic epidural.
- Trial name
- PVBS-USguided (NCT02865226)
- Testing
- paravertebral block by the anesthetist before incision (paravertebral block guided by ultrasound), paravertebral block by the thoracic surgeon at chest closure (paravertebral block visual).
- Where
- France
- Volunteers
- 50 people
- Sponsor
- CHU de Reims
Pre-emptive, Postoperative Pain
Ultrasound-Guided Mid-Point Transverse Process to Pleura Block for Thoracotomy Incisions
This study is designed to investigate the analgesic efficacy of pre-emptive ultrasound-guided midpoint transverse process to pleura (MTP) block for posterolateral thoracotomy in cardiothoracic surgeries.
- Conditions
- Pre-emptive, Postoperative Pain, Thoracotomy
- Trial name
- NCT05044858
- Testing
- Midpoint transverse process block group
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Pulmonary Malformation
Can Pre-operative Flexible 3D Models of Pulmonary Malformations Facilitate Thoracoscopic Resection
The National Rare Diseases plans, the ongoing MALFPULM PHRC and thoracoscopic advents in children, are remarkable improvements in understanding and managing lung malformations.
- Trial name
- 3DLP (NCT03913416)
- Testing
- 3D printed model, Control group
- Where
- France
- Volunteers
- 178 people
- Sponsor
- Hospices Civils de Lyon
Postoperative Pain
Comparison of Paravertebral Versus Epidural Block for Post-thoracotomy Pain Control
This is a randomized, assessor-blinded, non-inferiority clinical trial comparing continuous thoracic paravertebral block (BPV) versus continuous thoracic epidural block (BPD) for postoperative pain control in adult patients…
- Trial name
- NCT07763249
- Testing
- Continuous Thoracic Paravertebral Block, Continuous Thoracic Epidural Block
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hernia, Lung Cancer
Thoracotomy Closure Technique and Postoperative Pain Study: A Randomized Controlled Trial
The purpose of this study is to examine pain associated with thoracotomy (incision made during surgery to obtain access to your thoracic cavity) and how the closure technique may influence postoperative pain.
- Trial name
- NCT02063438
- Testing
- Pericostal suture technique, Intracostal suture technique
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- University of Michigan
Post-thoracotomy Pain
Continue ESPB & Continue ESPB Combined With SAPB for Thoracotomy
Patients who have undergone thoracotomy experience severe pain in the postoperative period. This pain leads to many complications.
- Trial name
- NCT06685445
- Testing
- Active Comparator: Continue Erector Spinae Plane Block, Active Comparator: Continue Erector Spinae Plane Block + Serratus Anterior Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Interscalene Block, Anterior Suprascapular Block
Interscalene Block Versus Anterior Suprascapular Block for Post-Thoracotomy Shoulder Pain
This study aims to compare the frequency of occurrence of ipsilateral shoulder pain in patients undergoing thoracotomy with ultrasound-guided interscalene block, anterior suprascapular block as adjunct to epidural and epidural…
- Conditions
- Interscalene Block, Anterior Suprascapular Block, Thoracotomy, Shoulder Pain
- Trial name
- NCT07424638
- Testing
- Interscalene block, Anterior suprascapular block, Epidural analgesia
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- National Cancer Institute, Egypt
Pain, Analgesia
Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardiac Surgery
This single-centre, prospective, randomised controlled trial investigates whether preoperative ultrasound-guided serratus posterior superior intercostal plane block (SPSIPB) reduces postoperative opioid consumption and pain…
- Trial name
- NCT07420712
- Testing
- Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Kartal Kosuyolu High Speciality Training and Research Hospital
Pain
The cryoICE™ CryoAnalgesia Study For Pain Management in Post thoRacic Procedures Via intercOSTal Cryoanalgesia (FROST)
The investigators propose to assess whether intra-operative intercostal cryoanalgesia using the cryoICE® probe (AtriCure®, Inc., 7555 Innovation Way, Mason, Ohio) provides superior post-operative analgesic efficacy as compared to…
- Trial name
- FROST (NCT02922153)
- Testing
- Cryoanalgesia, Standard of Care
- Where
- 5 sites in United States
- Volunteers
- 84 people
- Sponsor
- AtriCure, Inc.
Surgery
Prediction of Chronic Pain by the Pain Monitor
The skin conductance algesimeter (Pain Monitor™, Med-Storm Innovation AS, NO-0264 Oslo, Norway)) reflects the sympathetic nervous system by the measurement of the skin conductance of the palm of the hand.
- Trial name
- D3C (NCT01595711)
- Testing
- Pain Monitor
- Where
- 2 sites in France
- Volunteers
- 6 people
- Sponsor
- Hopital Foch
Cold Exposure
Simulation Study on Advanced Medical Procedures Under Extreme Environments
Background: In emergency situations in mountainous regions, medical professionals are often required to perform advanced medical procedures swiftly and efficiently.
- Trial name
- SIMEX-MED (NCT06640595)
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Traumatic Hemothorax
Pleural Suction Additional to Thoracostomy Tube for Traumatic Hemothorax
The primary treatment for traumatic hemothorax, is a thoracostomy tube. Some of these patients develop a clotted hemothorax by insufficient drainage. This complication needs surgical resolution and can generate an empyema.
- Trial name
- NCT04525365
- Testing
- Pleural aspiration
- Where
- Colombia
- Volunteers
- 250 people
- Sponsor
- Hospital Pablo Tobón Uribe
Neuropathic Pain, Thoracic Surgery, Video Assisted
Chronic Pain After Thoracotomy (Video Assisted Thoracic Surgery - VATS)
This is an explorative study investigating potential nerve injury after VATS.
- Conditions
- Neuropathic Pain, Thoracic Surgery, Video Assisted, Chronic Pain
- Trial name
- NCT01068457
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hypotension
Pilot Study: Paravertebral Analgesia vs Epidural Analgesia After Thoracotomy
Paravertebral analgesia is non-inferior to epidural analgesia for pain control and superior to epidural analgesia in terms of the main complication of hypotension.
- Trial name
- ParaEpi (NCT01700491)
- Testing
- Epidural Catheter 0.2% ropivacaine, Paravertebral Catheter 0.4% ropivacaine
- Where
- 2 sites in Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Thoracic Epidural Anesthesia, Paravertebral Block
Thoracic Epidural Anesthesia Versus Paravertebral Block for Awake Thoracotomy
This study aims to compare paravertebral block and thoracic epidural in awake thoracotomy.
- Conditions
- Thoracic Epidural Anesthesia, Paravertebral Block, Awake Thoracotomy
- Trial name
- NCT06974643
- Testing
- Thoracic epidural block, Paravertebral block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Thoracic Surgery
Continuous Erector Spinae Block Versus Thoracic Epidural Analgesia for the Prevention of Chronic Pain Following Thoracotomy: a Retrospective Study
Post-thoracotomy pain syndrome (PTPS) is a prevalent complication that significantly impacts patients' quality of life, with reported incidence ranging from 25% to 90%.
- Trial name
- NCT07677540
- Testing
- ESP block, Thoracic epidural
- Where
- Israel
- Volunteers
- 34 people
- Sponsor
- Meir Medical Center
Thoracotomy, Thoracotomy Analgesia
Compare the Perioperative Analgesic Effect of Ultrasound Guided Thoracic Paravertebral Block and Ultrasound Guided Serratus Anterior Block in Patients Undergoing Thoracotomy
The aim of this study is to compare the perioperative analgesic effect of ultrasound guided thoracic paravertebral block and ultrasound guided serratus anterior block in patients undergoing thoracotomy.
- Trial name
- thoracotomy (NCT06831578)
- Testing
- seratuse anterior plane block, paravertebral plane block
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University