Clinical trials: Thoracic Surgery, open to volunteers
Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8
Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer
This phase II trial studies how well respiratory muscle training before surgery works in preventing lung complications after surgery in patients with stage I-IIIB lung cancer.
- Conditions
- Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8, Stage IA2 Lung Cancer AJCC v8, Stage IA3 Lung Cancer AJCC v8
- Trial name
- NCT04067830
- Testing
- Best Practice, Laparoscopic Surgery, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Roswell Park Cancer Institute
Aortic Aneurysm, Aortic Aneurysm Abdominal
Prophylactic Suture Line Sealing With NE'X Glue R-eco in Cardiac and Vascular Surgery
This clinical study aims to evaluate the effectiveness and safety of using NE'X Glue R-eco to seal suture lines. The adhesive will be applied to reduce the risk of suture line bleeding in cardiac or vascular repair surgeries, a…
- Conditions
- Aortic Aneurysm, Aortic Aneurysm Abdominal, Valve Stenoses, Aortic, Valve Regurgitation, Mitral
- Trial name
- CLOSURE (NCT06918496)
- Testing
- Surgical placement of a prosthetic or biologic graft (patch), or an allograft for cardiac and (cardio)vascular repair.
- Where
- 2 sites in Belgium, Poland
- Volunteers
- 60 people
- Sponsor
- Grena Biomed Limited
Pneumothorax, Pleural Effusion
16F vs 24F Chest Drain After Minimally Invasive Lobectomy and/or Segmentectomy
The aim of the study is to evaluate postoperative pain in patients receiving a small-bore (16F) chest drain compared to those receiving the standard large-bore (24F) chest drain after minimally invasive pulmonary lobectomy and/or…
- Trial name
- ChestDrain (NCT06958848)
- Testing
- 16 F chest tube, 24 F chest tube, Early removal
- Where
- Switzerland
- Volunteers
- 124 people
- Sponsor
- University Hospital, Basel, Switzerland
Lung Cancer (Diagnosis), Patient-Reported Symptom Burden
Symptoms, Physical Function, and Recovery in Patients Receiving Lung Cancer Treatment Before Surgery
This study will examine how symptoms and physical abilities change during lung cancer treatment given before planned surgery, and how these changes relate to recovery after surgery.
- Conditions
- Lung Cancer (Diagnosis), Patient-Reported Symptom Burden, Physical Function
- Trial name
- NCT07853443
- Testing
- Longitudinal Assessment of Symptoms, Physical Function, and Postoperative Recovery
- Volunteers
- 360 people
- Sponsor
- Aerospace Center Hospital
Lung Cancer
Post-Operative Prediction of PulmonarY Function
Prediction of postoperative lung function is currently based on anatomical segment counting (ASC), which incorporates pulmonary function test (PFT) results.
- Trial name
- POPPY (NCT06494254)
- Where
- Australia
- Volunteers
- 15 people
- Sponsor
- University of Sydney
Lung Cancer, Progression, Disease
The Effects of Using Different Anesthetics on the Prognosis of Primary Lung Tumors and Its Mechanism of Action
This is a two-arm, parallel-group randomized clinical trial. Routine perioperative care would be performed in volunteers with primary early lung cancer.
- Conditions
- Lung Cancer, Progression, Disease, Anesthesia
- Trial name
- NCT05663242
- Testing
- Propofol, Sevoflurane
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Lung Neoplasms, Non-Small Cell Lung Cancer, Postoperative Complications
Smartphone-based Remote Symptom Monitoring to Improve Postoperative Rehabilitation Exercise Adherence After Video-assisted Thoracic Surgery (VATS) for Lung Cancer
Brief Summary: This randomized controlled trial aims to evaluate whether active remote symptom monitoring and management via a smartphone app utilizing electronic patient-reported outcomes (ePRO) can improve adherence to…
- Conditions
- Lung Neoplasms, Non-Small Cell Lung Cancer, Postoperative Complications, Patient Reported Outcome Measures, Telerehabilitation
- Trial name
- NCT05990946
- Testing
- ePRO based Remote Symptom Management provide by a mobile phone app
- Where
- China
- Volunteers
- 736 people
- Sponsor
- Zhongshan People's Hospital, Guangdong, China
Lung Cancer (Diagnosis), Pulmonary Complications in Surgical Patients
Effect of Mechanical Power-based Lung-protective Ventilation During One-lung Ventilation
The goal of this clinical trial is to determine whether a mechanical power-based lung-protective ventilation strategy during one-lung ventilation reduces the incidence of postoperative pulmonary complications in adult patients…
- Trial name
- NCT07772804
- Testing
- Mechanical power-based lung protective ventilation, Conventional lung protective ventilation
- Where
- South Korea
- Volunteers
- 164 people
- Sponsor
- Samsung Medical Center
Thoracic Surgery, Glycemic Variability
Comparison of Liposomal Bupivacaine Paravertebral Nerve Block Versus Intercostal Nerve Block on Postoperative Glycemic Variability in Patients Undergoing Minimally Invasive Pulmonary Resection: A Randomized Controlled Non-Inferiority Trial
In this randomized controlled non-inferiority trial, we will test whether liposomal bupivacaine intercostal nerve block is non-inferior to paravertebral nerve block for the coefficient of variation (CV) of glucose during the 0…
- Trial name
- NCT07754916
- Testing
- Paravertebral nerve block, Intercostal nerve block
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Xiangya Hospital of Central South University
Obese Patients
Impact of Thoracic Duct Ligation on Postoperative Weight Reduction in Obese Patients Receiving Minimally Invasive Lung Surgery: A Clinical Investigation
This clinical trial aims to investigate whether thoracic duct ligation (TDL) can improve obesity and lipid metabolism. The primary questions it seeks to answer are: Whether thoracic duct ligation can improve BMI and lipid…
- Trial name
- NCT06995599
- Testing
- Thoracic Duct Ligation (TDL)
- Volunteers
- 16 people
- Sponsor
- Yongxin Zhou
Thoracic Surgery, Anesthesia
Cerebral Oximetry-Guided Low FiO2 Strategies in Thoracic Surgery.
Brief Summary (Kısa Özet)The purpose of this study is to evaluate the safety and efficacy of a cerebral oximetry-guided low fraction of inspired oxygen (FiO_2) ventilation strategy compared to a standard high FiO_2 strategy in…
- Trial name
- NCT07659483
- Testing
- Standard High $FiO_2$ Strategy, Guided Low $FiO_2$ Strategy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dicle University
Chest Wall Tumor, Reconstructive Surgical Procedure
Chest Wall Reconstruction Cohort
Chest wall reconstruction following tumor or infection-related resections remains a challenging aspect of thoracic surgery, requiring restoration of structural stability and preservation of respiratory mechanics.
- Conditions
- Chest Wall Tumor, Reconstructive Surgical Procedure, Malignancy
- Trial name
- NCT07338006
- Testing
- chest wall reconstruction
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Health Sciences Lahore
Non-Small Cell Lung Cancer
To Explore the Safety and Efficacy of Hypervision Proton Surgery for Early-stage Non-small Cell Lung Cancer
This study was a single-center, single-arm clinical study to evaluate the safety and efficacy of hypervision proton surgery with single large fractionated doses (34GyE and 39GyE) in the treatment of early peripheral NSCLC.
- Trial name
- HyPROS-LC (NCT07195084)
- Testing
- Hypervision proton surgery
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Anhui Provincial Cancer Hospital
Comparative Effectiveness Research, Regional Block
Serratus Posterior Superior Intercostal Plane Block Versus Erector Spinae Plane Block in Thoracic Spine Surgeries
Spinal surgeries coincide with high level of pain due to extensive dissection and muscle retraction so inadequate pain control delays patient recovery, rehabilitation and also is an important source of patient dissatisfaction…
- Trial name
- NCT07646184
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Erector spinae block
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tanta University
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
A Wearable Biosensor Patch for Non-Invasive Monitoring for Patients Undergoing Abdominal or Chest Surgery
This clinical trial tests the feasibility and safety of a wearable biosensor patch for non-invasive monitoring for patients undergoing abdominal or chest surgery.
- Trial name
- NCT07612085
- Testing
- Biospecimen Collection, Electronic Health Record Review, Interview
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- City of Hope Medical Center
Frailty, Thoracic
Auricular Acupressure in Prehabilitation
Complementary medicine is recognized for its ability to enhance appetite, increase energy, reduce anxiety, decrease pain, and improve sleep, among many other benefits.
- Conditions
- Frailty, Thoracic, Prehabilitation, Lung Surgery
- Trial name
- NCT06516198
- Testing
- Auricular Acupressure
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Chicago
Lung Cancer (NSCLC)
Sublobar Wedge Resection or Stereotactic Radiotherapy Treatment of High-risk Patients With Early-stage Lung Cancer
In low-risk patients with stage I non-small cell lung cancer (NSCLC) surgical treatment with an anatomical resection is currently the standard of care.
- Trial name
- STRADOS (NCT07432802)
- Testing
- Stereotactic radiation therapy intervention, Surgical intervention
- Where
- 4 sites in Denmark
- Volunteers
- 182 people
- Sponsor
- Aarhus University Hospital
Thoracic Neoplasms
The Effects of a Family-Centered Tai Chi Exercise on Lung Function and Mental Health of Patients After Thoracoscopic Surgery
To explore the effect of a family-centered, eight-week, progressive sit-to-stand Tai Chi exercise on lung function and mental health in patients after thoracoscopic surgery_
- Trial name
- NCT06104774
- Testing
- Tai Chi Exercise
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
RATS Surgery, Thymectomy
Serratus Posterior Superior Intercostal Plane Block in Robotic-Assisted Thymectomy
This study aims to assess the effectiveness of the Serratus Posterior Superior Intercostal Plane Block (SPSIP Block) for postoperative pain control, reducing opioid analgesic consumption, minimizing postoperative respiratory…
- Conditions
- RATS Surgery, Thymectomy, Locoregional Anesthesia, Postoperative Pain Management
- Trial name
- SPRATS (NCT06545409)
- Testing
- Ultrasound-guided Serratus Posterior Superior Intercostal Plane Block performed with 0.25% bupivacaine
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lung Cancer
Real-world Clinical Outcomes of Patients With Early-stage Lung Cancer After the Surgery
The goal of this observational study is to evaluate the efficacy and long-term clinical outcomes of early-stage lung cancer patients who have received surgery using the real-world data.
- Trial name
- EarlyLC-RW (NCT06483698)
- Testing
- Sublobar resection, Lobectomy
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences