Clinical trials: Thoracic Nerve Block
Oxycodone
Oxycodone in Combination With Parathoracic Nerve Block is Used for Postoperative Analgesia in Lung Cancer
In this study, the effect of oxycodone combined with ultrasound-guided paravertebral nerve block on the postoperative analgesic effect of thoracoscopic lung cancer was investigated, and the effect and reasonable dose of oxycodone…
- Trial name
- NCT05742256
- Testing
- Oxycodone 1mg/kg, Oxycodone 1.5mg/kg, Sufentanil
- Volunteers
- 159 people
- Sponsor
- Qianfoshan Hospital
Melanoma, Non-small Cell Lung Cancer
A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid Tumors
The goal of this clinical research study is to learn how PLX3397 and pembrolizumab work together to affect cancer cells. PLX3397 is designed to target the receptor for CSF1 (CSF1R).
- Conditions
- Melanoma, Non-small Cell Lung Cancer, Squamous Cell Carcinoma of the Head and Neck, Gastrointestinal Stromal Tumor (GIST)
- Trial name
- NCT02452424
- Testing
- PLX3397, Pembrolizumab
- Where
- 12 sites in United States
- Volunteers
- 78 people
- Sponsor
- Daiichi Sankyo
Video Assisted Thoracic Surgery (VATS), Erector Spinae Plane Block
Efficacy of Erector Spinae Plane Block in Major Video-assisted Thoracic Surgery Compared to Intrathecal Morphine and Intercostal Nerve Block.
An ambispective observational study based on two groups (ITM and ICNB) from an earlier clinical trial conducted by our team(15) and a third group (ESPB) that received the new type of block, as we sought to assess the efficacy of…
- Conditions
- Video Assisted Thoracic Surgery (VATS), Erector Spinae Plane Block, Regional Anaesthesia, ERAS Programmes
- Trial name
- AESPVIMVIB (NCT07441161)
- Testing
- Spinal analgesia, regional block
- Where
- Spain
- Volunteers
- 113 people
- Sponsor
- Hospital Donostia
THoracotomy
Extrapleural Intercostal Catheter vs. Thoracic Epidural for Thoracotomy Pain
We will compare thoracic epidural anesthesia which is presently used for management of pain after thoracotomy to an intra-operatively placed extrapleural intercostal catheter. The study wil be double blinded and prospective.
- Trial name
- NCT00373633
- Testing
- Thoracic Epidural, Extrapleural Intercostal Catheter
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Virginia Commonwealth University
Horner's Syndrome
Horner's SD After Thoracic Epidural Block
This study prospectively evaluates the incidence of Horner's syndrome after thoracic epidural anesthesia following continuous thoracic epidural analgesia for mastectomy.
- Trial name
- NCT02130739
- Testing
- thoracic epidural anesthesia, mastectomy, Ropivacaine
- Where
- South Korea
- Volunteers
- 450 people
- Sponsor
- Soonchunhyang University Hospital
Abdominal Cancer
Radiofrequency and Chemical Neurolysis of Thoracic Splanchnic Nerve for Abdominal Cancer Pain
The study compares between the efficacy, safety and impact on the quality of life of radiofrequency thermocoagulation and chemical neurolysis of bilateral thoracic splanchnic nerves in the management of refractory pain which…
- Trial name
- RF (NCT03063112)
- Testing
- Radiofrequency generator device, Lidocaine, C arm fluoroscopic device
- Where
- Egypt
- Volunteers
- 79 people
- Sponsor
- South Egypt Cancer Institute
Pain
Study of the Effect of Regional Nerve Blocks on Pain and Inflammation After Video Assisted Thorascopic Lung Surgery
The purpose of this study is to compare: 1. The degree of systemic postoperative inflammation (cytokine measurement) with the degree of post-operative pain 2. The degree of pain and nausea and 3.
- Trial name
- VATS_IM (NCT00639795)
- Testing
- Thoracic Paravertebral Nerve Block
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Memorial Medical Center
Postoperative Pain, Lung Cancer
Pain After Lung Cancer Surgery - Comparing Traditional Versus Prolonged Release Nerve Blockades
To investigate the effect of liposomal bupivacaine compared with bupivacaine hydrochloride for intercostal blockades for patients undergoing Video-assisted thoracoscopic surgery.
- Conditions
- Postoperative Pain, Lung Cancer, Video Assisted Thoracoscopic Surgery, Blockades Neuromuscular
- Trial name
- NCT05038007
- Testing
- Liposomal bupivacaine, Bupivacaine Hydrochloride
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Jannie Bisgaard Stæhr
Pain, Postoperative
TPVB, PECSB, ESPB for Postmastectmy Pain
Aim of the work The aim of the study is to compare between the effects of ultrasound guided thoracic paravertebral block, pectoral nerve block II, and erector spinae block in management of pain during cancer breast surgeries.
- Trial name
- RCT (NCT05076773)
- Testing
- Ultrasound guided block, IV morphine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Menoufia University
Modified Thoracoabdominal Nerve Block (M-TAPA), Analgesic Technique
Bilateral Modified Thoracoabdominal Nerve Block as an Analgesic Technique in Comparison With Bilateral Thoracic Erector Spinae Plane Block in Abdominoplasty Operations
This study aimed to compare the analgesic effect of bilateral ultrasound-guided modified thoracoabdominal nerve block with bilateral ultrasound-guided erector spinae plane block in abdominoplasty surgery.
- Conditions
- Modified Thoracoabdominal Nerve Block (M-TAPA), Analgesic Technique, Thoracic Erector Spinae Plane Block, Abdominoplasty
- Trial name
- NCT07738900
- Testing
- General Anaesthesia using intravenous propofol, fentanyl intravenous, and atracurium besylate, Modified thoracoabdominal nerve block using 25 mL of bupivacaine 0.25%, Erector spinae plane block using 25 mL of bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Mansoura University
Paravertebral Peripheral Nerve Block, Acute Pain Management
Ultrasound-Assisted Paravertebral Block v. Traditional Paravertebral Block For Pain Control
The overall purpose of this research study is to compare the effectiveness of ultrasound assisted paravertebral block placement versus traditional "blind" technique for postoperative analgesia following thoracotomy or visually…
- Trial name
- NCT01949480
- Testing
- Thoracotomy, Video-Assisted Thoracoscopic Surgery (VATS)
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of Pittsburgh
Lung Cancer (Diagnosis)
Combination Versus Alone Liposomal Bupivacaine Blocks in Minimally Invasive Thoracic Surgery-1
The goal of this clinical trial is to assess how the location of local anesthetic medication affects pain control capabilities in adult patients undergoing thoracic(chest)-only minimally invasive surgery.
- Trial name
- CALMS-1 (NCT07254650)
- Testing
- Arm 1 "LipoB-I": Liposomal Bupivacaine via Multi-Level Intercostal Nerve Block, Arm 2 "LipoB-S": Liposomal Bupivacaine via Serratus Anterior Plane Block, Arm 3 "LipoB-C": Liposomal Bupivacaine Administered via Combination Block
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas Southwestern Medical Center
Postoperative Pain Following Modified Radical Mastectomy for Breast Cancer
Ultrasound-guided Thoracic Interfascial Plane Nerve Block Versus Erector Spinae Plane Block for Pain Control After Modified Radical Mastectomy
This study compares two methods of local pain control in patients undergoing Modified Radical Mastectomy, a common surgery for breast cancer( tumor in the breast) treatment.
- Trial name
- NCT06548646
- Testing
- Thoracic Interfascial Plane Block, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Safie ramez tewfeik abd el moneim
Thoracic Paravertebral Block, Anesthesia Induction
The Impact of Ultrasound-Guided Superficial and Deep Paravertebral Nerve Blocks at the Superior Costotransverse Ligament on Hemodynamics During the Induction Phase of Thoracoscopic Lung Lobectomy: A Multicenter, Double-Blind, Randomized Controlled Trial
This study aims to determine whether performing a paravertebral nerve block at the superficial surface of the superior costotransverse ligament (SCTL) (without needle penetration of the SCTL) is more effective in maintaining…
- Conditions
- Thoracic Paravertebral Block, Anesthesia Induction, Hypotension on Induction
- Trial name
- NCT06841822
- Testing
- SCTL superficial plane block, SCTL deep plane block group
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Postoperative Pain
Effect of Intercostal Nerve Block With Ropivacaine Combined With Mecobalamine on Chronic Pain After Thoracic Surgery
This project intends to investigate the effects of intercostal nerve block with ropivacaine combined with mecobalamin on chronic post-surgical pain (CPSP) in thoracic postoperative patients.
- Trial name
- NCT04217213
- Testing
- Intercostal nerve block
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Xuzhou Medical University
Anesthesia, Surgery
Pectoralis and Serratus Nerves Block in Thoracic Surgery
A new conceptual regional anesthesia the PECs II block (modified pectoral and serratus nerves block) has been described for pain control after thoracic surgery, one of the indications to perform this method is analgesia for…
- Conditions
- Anesthesia, Surgery, Block, Thoracic Injury
- Trial name
- NCT03023982
- Testing
- Bupivacaine Hydrochloride, Ultrasound, Thoracotomy
- Volunteers
- 168 people
- Sponsor
- Soroka University Medical Center
Nerve Block, Nephrectomy, Analgesia
QLB Versus PVB for Acute Pain and Quality of Recovery After Laparoscopic Partial Nephrectomy
This trial is a prospective, randomized, single-center, open-label, parallel-arm, blinded-analysis trial, the objective of which is to evaluate the effect of transmuscular quadratus lumborum block (TMQLB) in the pain relief and…
- Trial name
- NCT03975296
- Testing
- preoperative single-shot TMQLB, preoperative single-shot TPVB, patient controlled intravenous analgesia(PCIA)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Cui Xulei
Cancer
Study of RP2 Monotherapy and RP2 in Combination With Nivolumab in Patients With Solid Tumors
RP2-001-18 is a Phase 1, multicenter, open label, single agent dose escalation and combination treatment study of RP2 in adult subjects with advanced solid tumors, to determine the maximum tolerated dose (MTD) and recommended…
- Trial name
- NCT04336241
- Testing
- RP2, nivolumab
- Where
- 6 sites in Spain, United Kingdom
- Volunteers
- 36 people
- Sponsor
- Replimune, Inc.
Low Back Pain
Effectiveness of Thoracic Facet Joint Nerve Blocks
1. To demonstrate whether: i. Facet joint nerve blocks have therapeutic value beyond the duration of local anesthetic effect. ii.
- Trial name
- NCT00355706
- Testing
- Thoracic facet joint nerve blocks
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Pain Management Center of Paducah
Thoracic Anesthesia, Nerve Block
The Effects of Three Different Ultrasound-guided Nerve Blocks in VATS
Ultrasound-guided mid-point transverse process to pleura block, erector spinae plane block and paravertebral block are three different methods of nerve block, used for relieving postoperative pain in thoracic anesthesia.
- Conditions
- Thoracic Anesthesia, Nerve Block, Pain, Acute
- Trial name
- NCT04829409
- Testing
- Paravertebral block, ESP block, MTP block
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Huazhong University of Science and Technology