Clinical trials: Theta Burst Stimulation
Major Depression
TBS Over DLPFC in Elderly Refractory Depression
The study aim to examine the effect of Thea-burst stimulation over bilateral dorsolateral prefrontal cortex (DLPFC) among patients with LLD on mood condition and relevant biomarkers.
- Trial name
- NCT04872465
- Testing
- TBS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Chronic Pain, Post-traumatic Stress Disorder (PTSD)
Accelerated Neuromodulation for Concurrent Post-Traumatic Stress Disorder (PTSD) & Chronic Pain in Veterans
The ANCHOR study is testing a novel, non-invasive brain stimulation program designed specifically for Veterans experiencing concurrent post-traumatic stress disorder (PTSD) and chronic pain.
- Trial name
- ANCHOR (NCT07192536)
- Testing
- Transcranial magnetic stimulation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Legion Veterans Village Research Foundation
Generalized Anxiety Disorder (GAD)
MRI-Guided Accelerated cTBS for Generalized Anxiety Disorder
Generalized Anxiety Disorder (GAD) is a common psychiatric disorder associated with persistent anxiety, functional impairment, and incomplete response to existing treatments.
- Trial name
- NCT07640945
- Testing
- continuous theta burst stimulation(cTBS)
- Volunteers
- 75 people
- Sponsor
- Central South University
Smoking, Nicotine Dependence
Nicotine TMS EFT Smoking Pilot Study
Prior and recent evidence suggests a role of medial prefrontal cortex (MPFC) in cigarette smoking. Episodic Future Thinking (EFT) has also been shown to be associated with increased delayed discounting and reduced cigarette self…
- Conditions
- Smoking, Nicotine Dependence, Addiction, Smoking, Cigarette
- Trial name
- NCT03579953
- Testing
- Real cTBS
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Medical University of South Carolina
Alzheimer Disease
Transmagnetic Stimulation Pilot in Early Stage Alzheimer's Disease
Alzheimer's disease (AD) is a progressive neurodegenerative condition affecting 6.2 million individuals in the United States, resulting in an annual cost of care of $305 billion.
- Trial name
- NCT05292222
- Testing
- Intermittent theta burst stimulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- HealthPartners Institute
Stroke, Aphasia
pBFS-guided Dual-target cTBS for Aphasia After Stroke
The objective of this trial is to evaluate the effectiveness and safeness of personalized brain functional sectors (pBFS) technology-guided continuous theta burst stimulation (cTBS) on the inferior frontal gyrus (IFG) combined…
- Trial name
- NCT05957354
- Testing
- active continuous Theta Burst Stimulation
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Changping Laboratory
Arachnophobia, Phobia
TMS and Exposure Therapy
Spider phobia is an exceedingly common phobia throughout the world. The current standard treatment involves exposure therapy, which consists of a series of brief exposures of an individual to the thing they fear, in this case…
- Trial name
- NCT04019054
- Testing
- Intermittent Theta Burst Stimulation (iTBS), Ventromedial Prefrontal Cortex (vmPFC), Intermittent Theta Burst Stimulation (iTBS), vertex
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder, Theta Burst Stimulation
Explore the Impacts of Theta Burst Stimulation Over the Right Inferior Frontal Gyrus in Autism Spectrum Disorder: Combination of Clinical Symptoms, Neuropsychological Function and MRI
Exploring the therapeutic efficacy of Theta Burst Stimulation (TBS) over the right inferior frontal gyrus (RIFG) in autism, including changes in core symptoms, adaptive functioning, neuropsychological performance, and…
- Conditions
- Autism Spectrum Disorder, Theta Burst Stimulation, Right Inferior Frontal Gyrus
- Trial name
- NCT07579494
- Testing
- intermittent theta burst stimulation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Hemiplegia Following Ischemic Stroke
The Effects of Cerebellar Intermittent Theta Burst Stimulation on Gait, Balance, and Disease Anxiety In Stroke Patients
Our study was designed to investigate the effect of cerebellar intermittent theta burst stimulation (iTBS) combined with conventional rehabilitation methods on balance, gait and disease anxiety in patients with ischemic stroke…
- Trial name
- NCT06696547
- Testing
- Transcranial Magnetic Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara City Hospital Bilkent
Treatment Resistant Depression
Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression (SAINT-TRD)
This study evaluates an accelerated schedule of theta-burst stimulation using a transcranial magnetic stimulation device for treatment-resistant depression.
- Trial name
- aTBS (NCT03068715)
- Testing
- Active TBS-DLPFC, Open label TBS-DLPFC
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Depression
Prospective Cohort Study of Response and Tolerability of Accelerated Intermittent Theta-burst Stimulation (1W-AiTBS)
Intermittent theta-burst stimulation (iTBS), a variant of repetitive transcranial magnetic stimulation (rTMS), is a well-documented treatment for depression.
- Trial name
- NCT07449338
- Testing
- iTBS (intermittent theta-burst stimulation)
- Where
- 3 sites in Sweden
- Volunteers
- 36 people
- Sponsor
- Vastra Gotaland Region
Auditory Hallucinations
Efficacy and Safety of Bilateral Theta Burst Stimulation for the Treatment of Auditory Hallucinations
First clinical studies indicate an effect of repetitive transcranial magnetic stimulation(rTMS) in the treatment of auditory hallucinations (AH). However, effect size, optimal stimulation site and parameters are unclear.
- Trial name
- TBS-H (NCT01478880)
- Testing
- continuous theta burst stimulation (cTBS)
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- University Hospital Tuebingen
Alcohol Use Disorder, Alcohol Abuse
Theta Burst Stimulation as a Tool to Decrease Drinking in Treatment-seeking Alcohol Users
There is growing interest in the utilization of transcranial magnetic stimulation (TMS) as a novel, non-pharmacologic approach to decreasing alcohol use among treatment-seeking individuals with Alcohol Use Disorder (AUD).
- Conditions
- Alcohol Use Disorder, Alcohol Abuse, Alcohol Dependence, Craving
- Trial name
- NCT04154111
- Testing
- Real TBS to the vmPFC, Real TBS to the dlPFC
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Wake Forest University Health Sciences
Chronic Pain
Accelerated Theta Burst in Chronic Pain: A Biomarker Study
This study evaluates an accelerated schedule of theta-burst stimulation using a transcranial magnetic stimulation device for chronic pain.
- Trial name
- NCT03984201
- Testing
- Intermittent Theta Burst Stimulation (iTBS)
- Where
- United States
- Sponsor
- Stanford University
Major Depressive Disorder
Brainsway DTMS for Treatment of MDD Using iTBS
The safety and effectiveness of the BrainsWay deep transcranial magnetic stimulation (DTMS) device for the intended use of Major Depressive Disorder (MDD) using the intermittent theta-burst (iTBS) stimulation protocol will be…
- Trial name
- NCT04679753
- Testing
- Brainsway DTMS with intermittent Theta Burst Stimulation (iTBS), Brainsway DTMS with High Frequency (HF) Stimulation
- Where
- Canada
- Volunteers
- 177 people
- Sponsor
- Brainsway
Autism Spectrum Disorder
The Therapeutic Effects of Continuous Theta Burst Stimulation in Autism Spectrum Disorder
The investigator would like to investigate the impact of theta burst stimulation over left dorsolateral prefrontal cortex in autism spectrum disorder
- Trial name
- NCT04993144
- Testing
- continuous theta burst stimulation
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Major Depressive Disorder (MDD), Treatment Resistant Depression
EEG-Guided Transcranial Magnetic Stimulation for Adults With Depression
The purpose of this research is to see if an experimental treatment for depression called intermittent theta burst stimulation (iTBS), a form of transcranial magnetic stimulation (TMS) can be improved for better results using…
- Conditions
- Major Depressive Disorder (MDD), Treatment Resistant Depression, Major Depression
- Trial name
- CLEOPATRA (NCT07862205)
- Testing
- MagVenture TMS Therapy System with Localite Navigation System and actiCHamp EEG
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Anorexia Nervosa
Theta Burst Stimulation in Anorexia Nervosa: A Case Series
Anorexia Nervosa (AN) is a life-threatening eating disorder characterised by an intense fear of weight gain and disturbed body image, which motivates severe dietary restriction or other weight loss behaviours (e.g. purging).
- Trial name
- ANTS (NCT03979404)
- Testing
- Intermittent Theta Burst Stimulation
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- King's College London
Anxiety Disorders Generalized
A Pilot fMRI Study of TMS in Late-Life Severe Worry
Investigators will test a novel intervention through experimental therapeutic approach using fMRI-directed Intermittent Theta Burst Stimulation (iTBS), a high frequency TMS paradigm, for the treatment of severe, uncontrollable…
- Trial name
- TINA (NCT03577106)
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Carmen Andreescu
Diabetic Neuropathy, Painful
Theta Burst Brain Stimulation in Diabetic Neuropathy Patients With Neuropathic Pain: Investigating Neural Mechanisms
The purpose of the study is to determine the effects of a newer form of non-invasive brain stimulation (called transcranial magnetic stimulation or TMS) as a treatment in patients with painful diabetic neuropathy to examine its…
- Trial name
- NCT04988321
- Testing
- Prolonged continuous theta burst stimulation (pcTBS)
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Virginia Commonwealth University