Clinical trials: Therapeutic Alliance, open to volunteers
Depression - Major Depressive Disorder, Anxiety Disorders
AI-Guided CBT for Depression and Anxiety
This study aims to evaluate the effectiveness of an artificial intelligence (AI)-guided cognitive behavioral therapy (CBT) program for the treatment of mild depression and anxiety disorders in adults.
- Trial name
- AI-CBT-DA (NCT07576686)
- Testing
- AI-Guided Cognitive Behavioral Therapy, Cognitive Behavioral Therapy (CBT)
- Where
- Serbia
- Volunteers
- 120 people
- Sponsor
- Aleksandra Stojanovic
Spine, Low Back Pain
Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain
The goal of this randomized cross-over mechanistic trial is to compare pre- and post-level cortisol and oxytocin changes in patients with chronic spine pain who receive either a hand's on (massage) or a hand's off (talk-based)…
- Conditions
- Spine, Low Back Pain, Neck Pain
- Trial name
- COTHA (NCT06987786)
- Testing
- Massage, Talk-based therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
No Condition
Understanding How Peer Support Helps in Mental Health Care
The goal of this observational study is to better understand the psychological processes associated with professional peer support among adults using psychiatric services.
- Trial name
- PAIR-PROS (NCT07849621)
- Testing
- Perceptions of professional peer support and mental health professional support
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University of Bordeaux
Motivation, Alliance, Therapeutic
Animal-assisted Trauma-focused Therapy for Children and Adolescents
The study aims to investigate how the inclusion of an animal into a trauma-focused group therapy program (TF-CBT) affects therapy motivation of children and adolescents suffering from post-traumatic stress.
- Trial name
- AA TF-CBT (NCT05608551)
- Testing
- Animal-assisted trauma-focused therapy, Standard trauma-focused therapy
- Where
- 2 sites in Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Basel
Generalized Anxiety Disorder
Teletherapy vs. In-Person Cognitive Behavioral Therapy for Generalized Anxiety Disorder
The goal of this randomized controlled trial is to compare the clinical efficacy of teletherapy versus in-person third-wave cognitive behavioral therapy (CBT) in treating generalized anxiety disorder (GAD) among young individuals…
- Trial name
- TIPCBT-GAD (NCT07119515)
- Testing
- Third-Wave CBT via Teletherapy, Third-Wave CBT In-Person
- Where
- Pakistan
- Volunteers
- 25 people
- Sponsor
- Government College University Faisalabad
Depression, Anxiety
Identity-Based Transdiagnostic Therapy for Young People With Anxiety and Depression
Depression and anxiety are the most prevalent mental disorders among both the general population and young adults, and transdiagnostic treatments for these patients are mostly based on cognitive-behavioral therapy (CBT).
- Trial name
- IBTTYOUNG (NCT06384196)
- Testing
- Identity-Based Transdiagnostic Therapy (IBTT), Unified Protocol
- Where
- 2 sites in Spain
- Volunteers
- 138 people
- Sponsor
- University of Barcelona
Ischemic Stroke
Oriental Research AlliaNce of Acute Ischemic Stroke Given Endovascular Treatment
To determine the safety and efficacy of in situ ischemic postconditioning immediately after successful reperfusion in AIS patients underwnet EVT.
- Trial name
- ORANGE (NCT05024292)
- Testing
- rapid local ischemic postconditioning (RL-IPostC)
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Caregiver Anxiety, Acquired Brain Injury
Comprehensive Assessment of Rehabilitation Experience Using the SAFE Scale
Patients with severe acquired brain injury (sABI) and disorders of consciousness (DoC) require intensive interdisciplinary rehabilitation involving healthcare professionals, patients, and family caregivers.
- Conditions
- Caregiver Anxiety, Acquired Brain Injury, Caregiver Satisfaction and Connectedness to Clinic, Disorders of Consciousness Due to Severe Brain Injury
- Trial name
- CARE-SAFE (NCT07912372)
- Testing
- Caregiver training and administration of SAFE scale, Standard clinical care
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Therapeutic Alliances
HOLA Intervention Pilot
The patient-clinician relationship is fundamental to providing high-quality patient-centered medical care. A therapeutic alliance (TA) is a patient clinician relationship that is characterized by mutual caring, trust…
- Trial name
- NCT07576530
- Testing
- HOLA Intervention
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Rutgers, The State University of New Jersey
Diabetes Mellitus (Type 2), Glycemic Control for Diabetes Mellitus
Video-Based Lifestyle Counseling in Adults With Type 2 Diabetes.
This study evaluates the effectiveness of a 3-month video-based lifestyle intervention, focused on promoting healthy lifestyle habits (healthy eating and increased physical activity), on adults with type 2 diabetes mellitus…
- Conditions
- Diabetes Mellitus (Type 2), Glycemic Control for Diabetes Mellitus, Physical Activity, Healthy Eating
- Trial name
- LIDM2 (NCT07557264)
- Testing
- Video-based lifestyle intervention (own physician), Video-based lifestyle intervention (unknown physician)
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Cardenal Herrera University
Eating Disorder Symptom, Eating Disorders
INTERconNEcT-Eds: a Guided Self-help Mobile App to Improve Outcome in Eating Disorders
Eating disorders (EDs) are psychiatric illnesses characterised by pathological eating behaviours, ranging from protracted undereating to recurrent loss of control over eating.
- Conditions
- Eating Disorder Symptom, Eating Disorders, Eating Behavior
- Trial name
- NCT06551974
- Testing
- Guided self-help plus IPT, Guided self-help, TAU
- Where
- Italy
- Volunteers
- 242 people
- Sponsor
- University of Palermo
Eating Disorders
Developing Recommendations to Support Therapeutic Alliance in Eating Disorders Inpatient Treatment
The ALLIANCE study aims to understand and improve treatment relationships between staff and service users in inpatient eating disorder settings.
- Trial name
- ALLIANCE (NCT06961032)
- Where
- 3 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Norfolk and Suffolk NHS Foundation Trust
Depression
Neuroscience of Psychotherapy for Depression
The goal of this study is to learn the extent to which client-therapist brain activity may synchronize during a psychosocial intervention for depression symptoms.
- Trial name
- NCT06696001
- Testing
- Psychoeducation, Behavioral Activation
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of North Carolina, Chapel Hill
Ptsd, Sexual Violence
Evaluation of the Impact of Participation in a Psycho-education Program for Victims of Sexual Violence
Evaluation of the impact of a psycho-education program for victims of sexual violence, to determine the most efficient model to patients.
- Conditions
- Ptsd, Sexual Violence, Therapeutic Alliance
- Trial name
- PE-VVS (NCT06718387)
- Testing
- PsychoEducation Program
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Motivation, Alliance, Therapeutic
Canine-assisted Psychotherapy Motivation Alliance
The aim of the study is to investigate the needed extent and the way a dog is integrated into psychotherapeutic interventions for them to be motivating and alliance building for children and adolescents with psychiatric disorders…
- Trial name
- CAP (NCT05384808)
- Testing
- Standard Psychotherapy, Canine-assisted psychotherapy with dog actively integrated., Canine-assisted psychotherapy with dog passively integrated.
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University of Basel
Emotional Dysregulation, Therapeutic Alliance
Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth
Emotional dysregulation in justice-involved youth (JIY) is a condition that significantly impacts young people, their families, and juvenile justice and public health systems.
- Conditions
- Emotional Dysregulation, Therapeutic Alliance, Depression Disorder, Anxiety Disorders
- Trial name
- HEAL-SLOJSC (NCT07364799)
- Testing
- Multi-sensory emotional regulation intervention (Heal)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- SoundHeal
Rotator Cuff Related Shoulder Pain, Shoulder Pain
Contextually Enhanced Exercise Programs for Rotator Cuff-Related Shoulder Pain
The goal of this clinical trial is to learn whether adding personalized contextual factors to an exercise program can improve pain and function in people with rotator cuff-related shoulder pain.
- Conditions
- Rotator Cuff Related Shoulder Pain, Shoulder Pain, Rotator Cuff Injuries
- Trial name
- CONTEXT-RCRSP (NCT07428070)
- Testing
- Contextually Fixed Exercise Program, Contextually Enriched Personalized Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Istanbul Nisantasi University
Stroke
Effects of a Neurorehabilitation Program Based on CIMT and Non-invasive Neuromodulation Through C-tDCS on the Recovery of Paretic Upper Limb Function, Quality of Life, and Therapeutic Alliance in Women From the Araucanía Region Who Suffered a Stroke (CIMT + tDCS).
General Objective To determine the effects of a neurorehabilitation program based on Constraint-Induced Movement Therapy (CIMT) and non-invasive neuromodulation through cerebellar transcranial direct current stimulation (C-tDCS)…
- Trial name
- (CIMT - tDCS) (NCT07619703)
- Testing
- tDCS
- Where
- Chile
- Volunteers
- 24 people
- Sponsor
- Universidad de La Frontera
Hypertension, Hypertension Complicated
Improving Hypertension Control in Safety-Net Settings: The Boston Hypertension Equity Alliance in Treatment
High blood pressure (BP) or hypertension (HTN) affects over 100 million individuals in the US, increasing the risk of adverse outcomes, including stroke, myocardial infarction (MI), and chronic kidney disease (CKD).
- Trial name
- BHEAT (NCT06948838)
- Testing
- RBPM, MII
- Where
- 7 sites in United States
- Volunteers
- 16,895 people
- Sponsor
- Boston Medical Center