Clinical trials: Therapeutic Alliance
Therapeutic Alliances
HOLA Intervention Pilot
The patient-clinician relationship is fundamental to providing high-quality patient-centered medical care. A therapeutic alliance (TA) is a patient clinician relationship that is characterized by mutual caring, trust…
- Trial name
- NCT07576530
- Testing
- HOLA Intervention
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Rutgers, The State University of New Jersey
Hyperkinetic Disorder, Depressive Disorder
Mindfulness and Relaxation Interventions in Individual Psychotherapies for Children and Adolescents
The study 'Mindfulness and Relaxation interventions in Individual Training Psychotherapies for Children and Adolescents' (MARS-CA) aims to examine the effects of short session-introducing interventions with mindfulness elements…
- Conditions
- Hyperkinetic Disorder, Depressive Disorder, Anxiety Disorder
- Trial name
- MARS-CA (NCT04034576)
- Testing
- Cognitive behavior therapy of trainee therapists
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Heidelberg University
Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant
Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis
To evaluate the efficacy, safety and tolerability of various doses and durations of linezolid plus bedaquiline and pretomanid after 26 weeks of treatment in participants with either pulmonary XDR-TB, pre-XDR-TB, or treatment…
- Conditions
- Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant, Tuberculosis, MDR, Tuberculosis
- Trial name
- ZeNix (NCT03086486)
- Testing
- Pretomanid, Linezolid, Bedaquiline
- Where
- 11 sites in Georgia, Moldova and 2 more
- Volunteers
- 181 people
- Sponsor
- Global Alliance for TB Drug Development
COVID19
International ALLIANCE Study of Therapies to Prevent Progression of COVID-19
COVID-19 is a global pandemic. So far encouraging results have been shown in different parts of the world with the utilisation of hydroxycloroquine, zinc, and azithromycin, and early studies into some of these, plus some with…
- Trial name
- NCT04395768
- Testing
- Vitamin C, Hydroxychloroquine, Azithromycin
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- National Institute of Integrative Medicine, Australia
Affective Disorders, Anxiety Disorders
Routine Outcome Monitoring in Mental Health Outpatient
Scientific Background: Inherent gaps exist between the worlds of research and clinical therapy, especially in mental-health systems.
- Conditions
- Affective Disorders, Anxiety Disorders, Psychotic Disorders, Personality Disorders
- Trial name
- ROM-Shalvata (NCT02095457)
- Testing
- Frequent monitoring and feedback
- Where
- Israel
- Volunteers
- 900 people
- Sponsor
- Shalvata Mental Health Center
Diabetes Mellitus (Type 2), Glycemic Control for Diabetes Mellitus
Video-Based Lifestyle Counseling in Adults With Type 2 Diabetes.
This study evaluates the effectiveness of a 3-month video-based lifestyle intervention, focused on promoting healthy lifestyle habits (healthy eating and increased physical activity), on adults with type 2 diabetes mellitus…
- Conditions
- Diabetes Mellitus (Type 2), Glycemic Control for Diabetes Mellitus, Physical Activity, Healthy Eating
- Trial name
- LIDM2 (NCT07557264)
- Testing
- Video-based lifestyle intervention (own physician), Video-based lifestyle intervention (unknown physician)
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Cardenal Herrera University
Eating Disorder Symptom, Eating Disorders
INTERconNEcT-Eds: a Guided Self-help Mobile App to Improve Outcome in Eating Disorders
Eating disorders (EDs) are psychiatric illnesses characterised by pathological eating behaviours, ranging from protracted undereating to recurrent loss of control over eating.
- Conditions
- Eating Disorder Symptom, Eating Disorders, Eating Behavior
- Trial name
- NCT06551974
- Testing
- Guided self-help plus IPT, Guided self-help, TAU
- Where
- Italy
- Volunteers
- 242 people
- Sponsor
- University of Palermo
Men, Age Problem
Register of Therapeutical Patients Over 60 Years
Register for the study of the prevalence and burden of diseases, risk factors and outcomes of hospitalizations in older age groups in the countries of Eurasia.
- Conditions
- Men, Age Problem, Therapeutic Alliance
- Trial name
- ASCLEPIUS (NCT04295057)
- Testing
- Non-intervention
- Where
- Russia
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Eurasian Association of Therapists
Eating Disorders
Developing Recommendations to Support Therapeutic Alliance in Eating Disorders Inpatient Treatment
The ALLIANCE study aims to understand and improve treatment relationships between staff and service users in inpatient eating disorder settings.
- Trial name
- ALLIANCE (NCT06961032)
- Where
- 3 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Norfolk and Suffolk NHS Foundation Trust
Mental Disorders
RCT Social Cognition Training and Therapeutic Alliance Focused Therapy for Persons With Severe Mental Illness
The study evaluates the effectiveness of the social cognition and interaction training (SCIT), in comparison to both therapeutic alliance focused therapy (TAFT) and treatment as usual (TAU) among persons with severe mental…
- Trial name
- NCT02380885
- Testing
- SCIT, TAFT
- Where
- 5 sites in Israel
- Volunteers
- 158 people
- Sponsor
- Bar-Ilan University, Israel
Mental Disorders, Neurotic Disorders
Dynamics of Psychotherapy and Treatment Outcomes
The study is a 3-month controlled trial that aims to measure changes in patient's capacity (mindfulness, resilience, insight, working alliance) and intensity of neurotic symptoms.
- Conditions
- Mental Disorders, Neurotic Disorders, Personality Disorders
- Trial name
- NCT07017543
- Testing
- Psychotherapy Process-Outcome Study in Group Therapy
- Where
- Poland
- Volunteers
- 89 people
- Sponsor
- University Hospital in Krakow
Diagnosis, Psychiatric, Outpatient Followup of Psychiatric Problem
Therapists' Preferences for Client Characteristics and Their Influence on the Therapeutic Alliance
The research will examine psychotherapists' preferences for theoretical client characteristics, such as age, gender, personality characteristics and symptoms.
- Trial name
- NCT01799668
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Tobacco Dependence
Tobacco Treatment for Employable Californians, Total IMPACT Study
Previous findings indicate elevated risk for tobacco use among adults in California who are unemployed and seeking work. In a pilot study, tobacco use was associated with a longer duration of time out of work.
- Trial name
- TTEC (NCT02478697)
- Testing
- ProChange ExpertSystem
- Where
- 3 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Stanford University
Anxiety, PTSD
Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health
RESYNC-BH is a research study evaluating a personalized, non-drug brain-and-body treatment approach for adults with ongoing behavioral health symptoms such as depression, anxiety, trauma-related symptoms, sleep problems…
- Conditions
- Anxiety, PTSD, ADHD, Depression Disorders
- Trial name
- RESYNC-BH (NCT07812987)
- Testing
- AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Tactical Mind Research Coalition, Inc.
Depression
Neuroscience of Psychotherapy for Depression
The goal of this study is to learn the extent to which client-therapist brain activity may synchronize during a psychosocial intervention for depression symptoms.
- Trial name
- NCT06696001
- Testing
- Psychoeducation, Behavioral Activation
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of North Carolina, Chapel Hill
Psychedelic Experiences, Therapeutic Alliance
Ketamine Therapy Experiential Education Study
This study investigates the use of low-dose (0.5-0.75 mg/kg; maximum dose of 60 mg regardless of body weight) ketamine hydrochloride injection, USP administered intramuscularly to healthy clinicians as part of an experiential…
- Conditions
- Psychedelic Experiences, Therapeutic Alliance, Psychology, Perceptual
- Trial name
- KTEES1 (NCT05468047)
- Testing
- Ketamine hydrochloride injection
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Integrative Psychiatry Institute
Ptsd, Sexual Violence
Evaluation of the Impact of Participation in a Psycho-education Program for Victims of Sexual Violence
Evaluation of the impact of a psycho-education program for victims of sexual violence, to determine the most efficient model to patients.
- Conditions
- Ptsd, Sexual Violence, Therapeutic Alliance
- Trial name
- PE-VVS (NCT06718387)
- Testing
- PsychoEducation Program
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Drug Addiction
Comparing Acute and Continuous Drug Abuse Treatment: A Randomized Clinical Trial
The purpose of this 2 year study is to conduct a fully powered effectiveness trial comparing recovery trajectories of 200 drug dependent adults (the subjects) who will be randomly assigned to Treatment as Usual (TAU) or TAU +…
- Trial name
- NCT01003496
- Testing
- Treatment as Usual (TAU), TAU + Long-Term Recovery Management
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Wright State University
Substance Related Disorder, Personality Disorders
The Impact of the Use of the MAURISSE Application in People Suffering From an Addiction.
Substance Use Disorders (SUD) are associated with cognitive schemas that lead to care attrition and mistrust towards care. Considering this, establishing a strong, trustful relationship between the patient and the healthcare team…
- Trial name
- ALMA (NCT05964296)
- Testing
- The MAURISSE application use, Usual care
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Toulouse
Post-traumatic Headache, PTSD
Cognitive-Behavior Therapy for Posttraumatic Headache
The overall purpose of the study is to compare two talk therapies (Clinic-Based Cognitive Behavioral Therapy and Cognitive Processing Therapy-Cognitive Only) for the treatment of posttraumatic headache (PTHA) and co-morbid…
- Trial name
- NCT02419131
- Testing
- Behavioral Headache Therapy, Cognitive Processing Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- The University of Texas Health Science Center at San Antonio