Clinical trials: Therapeutic Alliance
Cancer
Impact of the Therapeutic Alliance on Reduction of Disparities in Latino End-of-Life Cancer Care
The purpose of the study is to examine perceptions, barriers, and facilitators of a therapeutic alliance (TA) between Latino/a advanced cancer patients and their oncologists.
- Trial name
- NCT04342611
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- City of Hope Medical Center
Spine, Low Back Pain
Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain
The goal of this randomized cross-over mechanistic trial is to compare pre- and post-level cortisol and oxytocin changes in patients with chronic spine pain who receive either a hand's on (massage) or a hand's off (talk-based)…
- Conditions
- Spine, Low Back Pain, Neck Pain
- Trial name
- COTHA (NCT06987786)
- Testing
- Massage, Talk-based therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
COVID19
International ALLIANCE Study of Therapies to Prevent Progression of COVID-19
COVID-19 is a global pandemic. So far encouraging results have been shown in different parts of the world with the utilisation of hydroxycloroquine, zinc, and azithromycin, and early studies into some of these, plus some with…
- Trial name
- NCT04395768
- Testing
- Vitamin C, Hydroxychloroquine, Azithromycin
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- National Institute of Integrative Medicine, Australia
Remote Therapeutic Monitoring, Digital Health
Assessing Feasibility of Evaluating Provider Experience With a Remote Therapeutic Monitoring Platform
: Remote therapeutic monitoring (RTM) platforms were increasingly deployed in Outpatient Rehabilitation to support continuous, between-visit communication, adherence to home exercise programs, and earlier identification of…
- Conditions
- Remote Therapeutic Monitoring, Digital Health, Proactive Patient Management, Rehabilitation
- Trial name
- NCT07790484
- Testing
- Feasibility, cross-sectional, quantitative survey
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Adly A Adam
Personality Disorders, Borderline Personality Disorder
Evaluation of AIT Study
Specialized treatment of personality disorders (PD) in youth has been neglected for a long time, because these disorders were not diagnosed before the age of 18.
- Trial name
- NCT02518906
- Testing
- Adolescent Identity Treatment, DBT-A
- Where
- 3 sites in Chile, Germany and 1 more
- Volunteers
- 60 people
- Sponsor
- Klaus Schmeck
Depression - Major Depressive Disorder, Anxiety Disorders
AI-Guided CBT for Depression and Anxiety
This study aims to evaluate the effectiveness of an artificial intelligence (AI)-guided cognitive behavioral therapy (CBT) program for the treatment of mild depression and anxiety disorders in adults.
- Trial name
- AI-CBT-DA (NCT07576686)
- Testing
- AI-Guided Cognitive Behavioral Therapy, Cognitive Behavioral Therapy (CBT)
- Where
- Serbia
- Volunteers
- 120 people
- Sponsor
- Aleksandra Stojanovic
Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Neoplasm in the Bone
BAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors
This phase Ib trial finds out the best dose, possible benefits and/or side effects of BAY1895344 and copanlisib in treating molecularly selected patients with solid tumors that have spread to other places in the body (advanced).
- Conditions
- Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm
- Trial name
- NCT05010096
- Testing
- Copanlisib, Elimusertib
- Sponsor
- M.D. Anderson Cancer Center
HIV (Human Immunodeficiency Virus), Substance Abuse Disorder
TechMPower: Advancing HIV/SUD Care and Service Delivery for People in Re-entry
The goal of this clinical study in one NY county is to pilot and refine implementation strategies aimed at improving delivery and uptake of evidence-based practices (EBPs) for HIV prevention/treatment and substance use disorder…
- Trial name
- TMP Project (NCT07088770)
- Testing
- Community Coalition CLS Workgroup/Network of Providers, Tech-mediated Training and Service Delivery, Multidisciplinary Implementation Team with Champion
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Columbia University
Suicide Attempt, Suicide
ASSIP, Attempted Suicide Short Intervention Program. Two Year Follow-Up Study
Objective Attempted suicide is the main risk factor for repeated suicidal behavior. However, evidence of the effectiveness of follow-up treatments for these patients is limited.
- Conditions
- Suicide Attempt, Suicide, Suicidal Ideation
- Trial name
- ASSIP (NCT02505373)
- Testing
- Attempted Suicide Short Intervention Program (ASSIP), Control Group (CG)
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Bern
Mental Disorders, Neurotic Disorders
Dynamics of Psychotherapy and Treatment Outcomes
The study is a 3-month controlled trial that aims to measure changes in patient's capacity (mindfulness, resilience, insight, working alliance) and intensity of neurotic symptoms.
- Conditions
- Mental Disorders, Neurotic Disorders, Personality Disorders
- Trial name
- NCT07017543
- Testing
- Psychotherapy Process-Outcome Study in Group Therapy
- Where
- Poland
- Volunteers
- 89 people
- Sponsor
- University Hospital in Krakow
Motivation, Alliance, Therapeutic
Canine-assisted Psychotherapy Motivation Alliance
The aim of the study is to investigate the needed extent and the way a dog is integrated into psychotherapeutic interventions for them to be motivating and alliance building for children and adolescents with psychiatric disorders…
- Trial name
- CAP (NCT05384808)
- Testing
- Standard Psychotherapy, Canine-assisted psychotherapy with dog actively integrated., Canine-assisted psychotherapy with dog passively integrated.
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University of Basel
Recurrent Glioblastoma, Recurrent Adult Brain Tumor
Vaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery
This randomized phase II trial studies how well giving vaccine therapy with or without bevacizumab works in treating patients with recurrent glioblastoma multiforme that can be removed by surgery.
- Conditions
- Recurrent Glioblastoma, Recurrent Adult Brain Tumor, Gliosarcoma
- Trial name
- NCT01814813
- Testing
- HSPPC-96, bevacizumab
- Where
- 417 sites in United States
- Volunteers
- 90 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Achilles Tendinopathy
Managing Achilles Pain II
Although some people are more at risk than others, developing a painful Achilles tendon (known as Achilles tendinopathy) can affect anyone. It is a common and disabling condition affecting walking, running and work.
- Trial name
- MAP II (NCT05105269)
- Testing
- Treatment from a physiotherapist
- Where
- United Kingdom
- Volunteers
- 159 people
- Sponsor
- University of Essex
Borderline Personality Disorder, Emotion Dysregulation
Testing an Alliance-Focused Dialectical Behaviour Therapy Training for Borderline Personality Disorder
The study evaluates the feasibility, acceptability, and effect sizes of two alliance-focused dialectical behavior therapy (DBT) training interventions to improve therapists' abilities to recognize and respond to alliance ruptures…
- Trial name
- NCT07119541
- Testing
- Alliance-Focused Dialectical Behavior Therapy plus Deliberate Practice, Alliance-Focused Dialectical Behavior Therapy plus Reflective Practice
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- York University
Therapeutic Alliance, Empathy
The Influence of the Cultural Formulation Interview on Therapeutic Work Alliance
The increased cultural diversity in client populations in mental healthcare settings led to the addition of the Cultural Formulation Interview (CFI) in the Diagnostic and Statistical Manual for Mental Disorders (DSM-5).
- Trial name
- CFITWA (NCT05788315)
- Testing
- Cultural Formulation Interview
- Where
- Netherlands
- Volunteers
- 164 people
- Sponsor
- Tilburg University
Diabetes Mellitus (Type 2), Glycemic Control for Diabetes Mellitus
Video-Based Lifestyle Counseling in Adults With Type 2 Diabetes.
This study evaluates the effectiveness of a 3-month video-based lifestyle intervention, focused on promoting healthy lifestyle habits (healthy eating and increased physical activity), on adults with type 2 diabetes mellitus…
- Conditions
- Diabetes Mellitus (Type 2), Glycemic Control for Diabetes Mellitus, Physical Activity, Healthy Eating
- Trial name
- LIDM2 (NCT07557264)
- Testing
- Video-based lifestyle intervention (own physician), Video-based lifestyle intervention (unknown physician)
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Cardenal Herrera University
Post-traumatic Headache, PTSD
Cognitive-Behavior Therapy for Posttraumatic Headache
The overall purpose of the study is to compare two talk therapies (Clinic-Based Cognitive Behavioral Therapy and Cognitive Processing Therapy-Cognitive Only) for the treatment of posttraumatic headache (PTHA) and co-morbid…
- Trial name
- NCT02419131
- Testing
- Behavioral Headache Therapy, Cognitive Processing Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Psychiatric Decompensation
Mélisses Garden: Effect on Anxious State in Adult Patients Hospitalized in Psychiatry
Each hospitalization leads to stress and anxiety. This is particularly true in psychiatry, because of "decompensation". That is why therapeutic treatments are delivered quickly to treat these symptoms and to allow a better…
- Trial name
- JDM (NCT02666339)
- Testing
- Usual care, Hortitherapy
- Where
- France
- Volunteers
- 211 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Hypertension, Hypertension Complicated
Improving Hypertension Control in Safety-Net Settings: The Boston Hypertension Equity Alliance in Treatment
High blood pressure (BP) or hypertension (HTN) affects over 100 million individuals in the US, increasing the risk of adverse outcomes, including stroke, myocardial infarction (MI), and chronic kidney disease (CKD).
- Trial name
- BHEAT (NCT06948838)
- Testing
- RBPM, MII
- Where
- 7 sites in United States
- Volunteers
- 16,895 people
- Sponsor
- Boston Medical Center
Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
SAR439459 and Cemiplimab for the Treatment of Advanced or Unresectable Solid Tumors, Strategic Alliance, TACTIC TRIAL
This is a phase Ib trial with SAR439459, a TGF-beta inhibitor, in combination with cemiplimab, a PD-L1 inhibitor, in patients with solid tumors that have spread to other places in the body (advanced) or cannot be removed by…
- Conditions
- Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Unresectable Malignant Solid Neoplasm
- Trial name
- NCT04729725
- Testing
- Anti-TGF-beta Monoclonal Antibody SAR-439459, Cemiplimab
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center