Clinical trials: Testosterone
Wellness, Health
A Crossover Clinical Trial Investigating the Effects of Geranylgeraniol (GG) Supplementation on Testosterone Levels in Healthy Men and Women Over an 18-week Period
The primary purpose of this study is to investigate the effects of geranylgeraniol (GG) supplementation on testosterone levels in middle-aged (40 to 65 years) healthy men and women.
- Trial name
- NCT06747624
- Testing
- Geranylgeraniol 300 mg
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Designs for Health
Hypogonadism
Cardiovascular Outcomes of Low Testosterone
This study plans to learn more about heart and vascular aging in men. In some men as they get older, testosterone levels fall below the normal range for young men. Also, as men get older cardiovascular health worsens.
- Trial name
- CardioVOLT (NCT02758431)
- Testing
- Acyline, Testosterone Gel, Arimidex
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy
Single Effort in Air Temperature of Minus 10°C
Exercise in the cold is an attractive option for many athletes. Erythrocyte aggregation, as one of the main rheological parameters, constitutes an important indicator of microcirculation and oxygen transport capacity in the human…
- Trial name
- NCT07664072
- Testing
- cold, neutral
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University School of Physical Education, Krakow, Poland
Hypogonadism, Spinal Cord Injury
Provocative Testing Using LHRH and hCG of the Pituitary-Gonadal Axis in Persons With Spinal Cord Injury.
There is evidence that has shown that serum testosterone levels are low in persons with chronic spinal cord injury (SCI). The question arises as to whether the defect in testosterone production is from the hypothalamic pituitary…
- Trial name
- NCT00223860
- Testing
- Human chorionic gonadotropin (hCG), Luteinizing hormone releasing hormone (LHRH)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Erectile Dysfunction, Nocturia, Short Term Insomnia, Obstructive Sleep Apnea
Effects of Nightshift Work and Sleep Disturbances on Erectile Function
We aim to observe the unwanted effects of nightshift work and short term insomnia on erectile function of men aged between 25 to 60 years.
- Trial name
- NCT04707807
- Testing
- IIEF-5
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Contraception
NES Gel-1, To Evaluate Nestorone Gel in Combination With Testosterone Gel
The purpose of this study is to determine the usefulness of two transdermal gels to be used in the future development for a male contraceptive.
- Trial name
- NES-1 (NCT00229593)
- Testing
- Nestorone gel, Testosterone Gel
- Where
- 2 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Washington
Panhypopituitarism
Testosterone Gel Applied to Women With Pituitary Gland Problems
The principal aim of this study is to evaluate if application of testosterone gel leads to improvement in measures of sexual function, thinking ability and quality of life in women with dysfunction of the pituitary gland.
- Trial name
- NCT00144391
- Testing
- Transdermal Testosterone gel
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Female Hormone Profile
Acute Vitamin D Supplementation on Testosterone in Females
Participation will take place over two visits to the Clinical Exercise Research Center (CERC) at the University of Southern California Health Sciences Campus.
- Trial name
- NCT06610968
- Testing
- Vitamin D (Cholecalciferol )
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Insulin Resistance, Postmenopause
Insulin Resistance and Testosterone in Women
The purpose of this research study is to determine if a relationship between insulin resistance (IR) and testosterone (T) exists in women who have already gone through menopause.
- Trial name
- NCT00123110
- Testing
- metformin, leuprolide injection
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Muscular Weakness, Sexual Behavior
Supplement Study: Strength, Testosterone, Sexual Function, Quality of Life
Decreased muscle mass (sarcopenia) and strength (dynapenia) are common during aging, with a rate of muscle mass loss that is approximately 6% per decade between 30 and 70 years of age.
- Conditions
- Muscular Weakness, Sexual Behavior, Quality of Life
- Trial name
- NCT03457740
- Testing
- Formula 1, Formula 2
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Hypogonadism, Male
Assessment of Blood From Men Receiving Oral TU in Various Collection Tubes
To describe the rate of post-collection TU to testosterone conversion, as manifested by increases in testosterone concentration, in Plain tubes held at room temperature and sodium fluoride (NaF)-ethylenediaminetetraacetic acid…
- Trial name
- NCT03973840
- Testing
- Testosterone Undecanoate
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Clarus Therapeutics, Inc.
Healthy
The Role of 5-alpha Reductase in Mediating Testosterone Actions
In normal men, the male hormone testosterone affects a number of things in the body including muscle function and sexual function.
- Trial name
- 5aR (NCT00493987)
- Testing
- Testosterone Enanthate, Dutasteride
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
PCOS
Theca Cell Function in Adolescents With Polycystic Ovary Syndrome (PCOS)
In women with polycystic ovary syndrome (PCOS), the cardinal physiological abnormality is excessive ovarian androgen production marked by increased serum testosterone (T) and androstenedione (A) levels.
- Trial name
- NCT01154192
- Testing
- Dexamethasone, recombinant human chorionic gonadotropin (r-hCG)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Hypogonadism
To Determine the Effects of Deodorant, Antiperspirant and Washing on the Pharmacokinetics of 2% Testosterone MD Lotion
Testosterone replacement treatment is the most effective way of treating hypogonadism in men. Acrux has a propriety testosterone replacement product, Testosterone MD-Lotion and this study will evaluate the impact of application…
- Trial name
- MTE10 (NCT00857168)
- Testing
- Testosterone MD-Lotion
- Where
- Australia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Acrux DDS Pty Ltd
Contraception
Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP 5) Testicular Aspiration Addendum
This study is being offered to all participants of the ACY-5 study as an optional addition to the male contraceptive study in which they participated. Participation is voluntary.
- Trial name
- IHOP-5 (NCT00156650)
- Testing
- Acyline, Testosterone Gel, Depo-Medroxyprogesterone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Washington
Testosterone Deficiency, Male Hypogonadism
Anthropometric, Functional and Lifestyle Factors Associated With Testosterone Levels in Middle-Aged Men
Decreased testosterone levels in middle-aged men are associated with multiple metabolic, functional and psychosocial consequences.
- Trial name
- TESMEN (NCT07476222)
- Testing
- Observational Assessment
- Where
- Uzbekistan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Andijan State Medical Institute
Testosterone Deficiency, Estrogen Deficiency
Use of Infrared Photomodulation for Hormonal Balance (Joovvin' for Hormonal Health)
8-week pilot study looking at the impact of Joovv's infrared photo modulation product on male and female hormone levels.
- Trial name
- NCT04245527
- Testing
- Joovv Infrared Light Device
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- ProofPilot
Menopause
Transdermal Testosterone Nanoemulsion in Women Libido
This is a double-blind, randomized, placebo-controlled study. Seventy women, aged 35-75 years, with treatment-emergent loss of libido will be randomly allocated to the treatment with a Transdermal nanoemulsion of Testosterone…
- Trial name
- Biolipid/B2 (NCT02445716)
- Testing
- Testosterone
- Where
- 3 sites in Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Potiguar
Hypogonadism
Survey of Testosterone Levels in Male Cancer Patients
The purpose of this study is to survey the total serum testosterone levels in male patients with hormone-independent malignancies. The prevalence of hypogonadism is not known, but is thought to be significant.
- Trial name
- NCT00483418
- Where
- United States
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Beth Israel Medical Center
Post-menopausal Period
Pharmacokinetics, Pharmacodinamic and Safety of Testosterone Gel 1%
This is a Phase I, open-label, parallel trial to evaluate Pharmacokinetics, Pharmacodynamics and Safety of Testosterone gel 1% for topic usage in post-menopausal women, for 28 days
- Trial name
- NCT02667561
- Testing
- Testosterone gel 1% 2.2 mg, Testosterone gel 1% 4.4 mg, Testosterone gel 1% 8.8 mg
- Volunteers
- healthy volunteers welcome
- Sponsor
- Biolab Sanus Farmaceutica