Clinical trials: Telomere Disease
Leukemia
Biomarkers in Samples From Young Patients With Acute Myeloid Leukemia
RATIONALE: Studying bone marrow samples from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT01247584
- Testing
- DNA analysis, mutation analysis, polymerase chain reaction
- Volunteers
- 234 people
- Sponsor
- Children's Oncology Group
Kidney Disease, Chronic, Kidney Failure Chronic
Physical Exercise and Biomolecular Analysis to Reduce Uremic Toxins in Chronic Kidney Disease: An Exploratory Study
The accumulation of uremic toxins is detrimental to physiological systems and induces premature biological aging. Renal function assessment methods, such as predictive formulas, may be influenced by ancestry in Brazilians, given…
- Trial name
- DRC_LExS (NCT06910475)
- Testing
- Resistance training, Endurance training, Concurrent training
- Where
- Brazil
- Volunteers
- 1,600 people
- Sponsor
- Catholic University of Brasília
Aging, Stress
Fitness, Cellular Aging, and Caregiver Stress Study
The purpose of this study is to determine whether an aerobic training intervention will alter markers of immune cell aging, improve exercise capacity and blood pressure and decrease psychological distress over 24 weeks in 32…
- Conditions
- Aging, Stress, Disease Risk
- Trial name
- FAST (NCT01993082)
- Testing
- Aerobic Training Intervention
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Telomere Shortening, Bone Marrow Failure
Study to Evaluate of EXG34217 in Patients With Telomere Biology Disorders With Bone Marrow Failure
This is a Phase I/II, open label, single center study to assess the safety and tolerability of EXG34217 in bone marrow failure patients with telomere biology disorders.
- Trial name
- NCT04211714
- Testing
- EXG34217
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Elixirgen Therapeutics, Inc.