Clinical trials: Teeth Loss, open to volunteers
Bone Loss, Jaw, Edentulous
Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
The objective of this study is to test the bone formation capacity of a 3D printed scaffold with a plastic material called Polycaprolactone (PCL), compared to the use of synthetic bone grafts, for bone formation in the maxilla or…
- Conditions
- Bone Loss, Jaw, Edentulous, Edentulous Mouth, Jaw Fractures
- Trial name
- OSTEOPRINT (NCT06773923)
- Testing
- PCL Scaffold, PTFE + Bio-Oss®
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Tooth Loss, Alveolar Bone Loss
Immediate Molar Implants With Customized Healing Abutments in Different Post-Extraction Socket Classes
Immediate implant placement into a fresh extraction socket shortens overall treatment time and reduces the number of surgical procedures, but the fit between the implant and the socket walls, and the resulting soft-tissue…
- Conditions
- Tooth Loss, Alveolar Bone Loss, Jaw, Edentulous, Partially
- Trial name
- IMPLA-CHA (NCT07801573)
- Testing
- Immediate implant placement with customized healing abutment
- Where
- Bulgaria
- Volunteers
- 60 people
- Sponsor
- Plovdiv Medical University
Peri-implant Soft Tissue Deficiency, Partial Edentulism
Soft Tissue Augmentation Around Dental Implants Using Connective Tissue Graft, Submerged Tenting Abutment, or Sub-crestal Implant Placement
Peri-implant soft tissue thickness is an important determinant of the long-term stability and success of dental implants. Patients with a thin peri-implant soft tissue phenotype are at increased risk of soft tissue recession…
- Conditions
- Peri-implant Soft Tissue Deficiency, Partial Edentulism, Tooth Loss
- Trial name
- NCT07714265
- Testing
- subepithelial connective tissue graft, Submerged Tenting Abutment, Sub-crestal Implant Placement
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Misr International University
Missing Teeth
Post Market Clinical FoIIow up (PMCF) Medical Device (MD) of Z-Systems Monotype Zirconia Dental Product: Z5m Dental Implants Registry
Commercially pure (CP) titanium is the gold standard to produce dental implants because it has a huge volume of scientific publications over a period of more than 50 years, it is cheap and simple to produce (i.e., making dental…
- Trial name
- NCT06007365
- Testing
- Z5m Dental Implants
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- Z-Systems
Edentulism, Tooth Loss
5-Years PMCF Study of Ceramic Dental Implants One-piece Versus Two-piece.
The goal of this cohort observational study is to compare in the survival rate of ceramic dental implants placed in patients with missing or hopeless teeth .
- Trial name
- 240101 (NCT06287346)
- Testing
- dental implant
- Where
- 2 sites in United States, Spain
- Volunteers
- 652 people
- Sponsor
- CeraRoot SL
Tooth Loss and Rehabilitation With Telescopic Crown Prostheses
Rigid Versus Non-Rigid Digitally Fabricated Telescopic Double Crown Prosthesis
This study aims to compare the clinical and patient satisfaction outcomes of rigid versus non-rigid digitally fabricated telescopic double crown prostheses supported by teeth and implants.
- Trial name
- NCT07682623
- Testing
- Rigid telescopic double crown prosthesis, Non-rigid telescopic double crown prosthesis
- Volunteers
- 10 people
- Sponsor
- Mansoura University
Alveolar Bone Loss, Tooth Loss / Rehabilitation
Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem Membranes
After tooth extraction, the surrounding bone and soft tissue may undergo dimensional reduction. Socket preservation involves placement of a bone graft into the extraction socket and coverage with a membrane to support healing…
- Conditions
- Alveolar Bone Loss, Tooth Loss / Rehabilitation, Alveolar Bone Grafting, Socket Preservation
- Trial name
- NCT07856693
- Testing
- NOVAMag Membrane, permamem Membrane, Alveolar Socket Preservation With an Allogeneic Bone Graft
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Immediate Dental Implant Placement, Connective Tissue Graft
Immediate Implants in Front Teeth With Bone Loss: Regeneration and Temporary Crown in a Randomized Clinical Study
This clinical trial investigates the biological and clinical outcomes of immediate implant placement in aesthetic areas presenting with buccal bone dehiscence.
- Conditions
- Immediate Dental Implant Placement, Connective Tissue Graft, Connective Tissue Graft Harvesting, Soft Tissue Management in Subcrestal Dental Implants
- Trial name
- GBR / RCT (NCT07415486)
- Testing
- immediate implant placement with DBBM-C and connective tissue graft, immediate implant placement with DBBM-C with collagen membrane
- Volunteers
- 24 people
- Sponsor
- Universitat Internacional de Catalunya
Vertical Implant Position, Delayed Implant Placement With Immediate Loading
Influence of Vertical Implant Position on Marginal Bone Loss in Cases With Thin Phenotype
The goal of this clinical trial is to learn if vertical position of the dental implant will affect the bone around the implant in place of a missing tooth that happens to be bounded by two natural teeth.
- Conditions
- Vertical Implant Position, Delayed Implant Placement With Immediate Loading, Tooth Loss / Rehabilitation
- Trial name
- NCT07483086
- Testing
- Delayed implant with immediate temporization placed 2 mm subcrestal level, Delayed implant with immediate temporization placed at the crestal level
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Tooth Loss, Dental Implant
A 36-month Analysis of the Clinical Performance of Individualized CAD/CAM-produced Dental Implants: a Cohort Study
The goal of this prospective cohort study is to evaluate the clinical performance of a new generation of customized CAD/CAM pre-fabricated root-analog dental implants over a 36-month period.
- Trial name
- NCT06576284
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Bone Density, Bone Level
Comparison Between Socket Shield and Conventional Techniques in Immediate Implant Placement.
The goal of this randomized clinical trial is to compare whether immediate implant placement using the socket-shield technique can better preserve bone density, bone level, and peri-implant tissue health compared to conventional…
- Conditions
- Bone Density, Bone Level, Peri-Implant Tissues, Socket Shield Technique Implant Placement
- Trial name
- NCT07761442
- Testing
- Conventional Technique, Socket-Shield Technique
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Minia University
Missing Teeth
Short-term Observation on the Clinical Application Effect of Astra Tech Implant EV Short Implants for Maxillary Sinus Elevation
Short-term comparison of clinical application effects of Astra OsseoSpeed EV short implants and conventional implants for maxillary sinus elevation
- Trial name
- NCT07271134
- Testing
- short implants (L=6.3mm), short implants (L=8mm), conventional implants (L=9mm)
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Linhu Wang
Hopeless Tooth in Esthetic Zone, Loss of Soft and Hard Tissue Around Implant
Peri-implant Tissue Changes Using Dual Zone Concept With Connective Tissue Graft Versus Concentrated Growth Factor
Tooth extraction not only alters the bony architecture of the alveolar ridge, but it also has an impact on the surrounding soft tissues.
- Conditions
- Hopeless Tooth in Esthetic Zone, Loss of Soft and Hard Tissue Around Implant, Immediate Implant Placement
- Trial name
- NCT06728696
- Testing
- Immediate implant with with dual zone technique using concentrated growth factor graft., Immediate implant with dual zone technique using connective tissue graft.
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Implants, TNF-alpha Inhibitors
Dental Implant Healing With TNF-Alpha Inhibitors
The goal of this pilot study is to learn about healing after dental implant placement in patients taking a class of biologic drug called Tumor Necrosis Factor or TNF-alpha antagonist or inhibitor.
- Conditions
- Dental Implants, TNF-alpha Inhibitors, Edentulism
- Trial name
- NCT06538870
- Testing
- Placement of dental implants
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tooth Loss
Influence of Healing Time on the Outcomes of Alveolar Ridge Preservation in Periodontally Compromised Extraction Sockets
The goal of this clinical trial is to histologically, clinically, and radiographically evaluate the healing sequelae of periodontally compromised extraction sockets grafted with Bio-Oss Collagen® at 3 and 6 months following tooth…
- Trial name
- NCT06654141
- Testing
- Alveolar ridge preservation
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Malocclusion, Canine Retraction
Comparing Ligation Methods During Canine Retraction Stage Using Conventional Brackets
The goal of this Randomized Controlled Trial (RCT) is to determine the most effective way to tie the main wire to the regular orthodontic brackets during the stage of orthodontic treatment where the canines are retracted.
- Trial name
- NCT07063186
- Testing
- Group A - Elastomeric power chain on all bracket wings., Group B - Stainless steel ligatures with elastomeric power chain placed over all bracket wings., Group C - Elastomeric modules on mesial wings and power chain on distal wings.
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- International Islamic University Malaysia
Tooth Loss / Rehabilitation, Dental Implant
Standard- and Micro-Dose rhBMP-2 for Implant Stability, Marginal Bone Loss, and Postoperative Sequelae: A Double-Blind Randomized Controlled Trial
This study will compare the effect of standard-dose and micro-dose recombinant human bone morphogenetic protein-2 (rhBMP-2) with a placebo control on dental implant stability in the posterior mandible.
- Conditions
- Tooth Loss / Rehabilitation, Dental Implant, Osseo-Integrated Implants
- Trial name
- SMBMP (NCT07696299)
- Testing
- Standard-dose rhBMP-2, Micro-dose rhBMP-2, Sterile Normal Saline
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- University of Baghdad
Bone Loss
All-on-X Stackable Guides for Maxillary Terminal Dentition
This retrospective study will evaluate the clinical performance of maxillary All-on-X(full-arch implant-supported rehabilitation) implant rehabilitation using stackable guided surgery and immediate loading.
- Trial name
- NCT07353619
- Testing
- Maxillary All-on-X implant rehabilitation using a fully digital stackable guided surgery workflow with immediate loading.
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Missing Teeth
Assessment of Hard and Soft Tissue Changes Following XCM Versus FGG Simultaneous With Delayed Dental Implant Placement
Teeth loss are usually associated with alterations of extraction sockets result in obviously absorbed alveolar ridges and are often accompanied with soft tissue atrophy such as narrow keratinized tissue and a shallow vestibule.
- Trial name
- NCT07080177
- Testing
- Free gingival graft simultaneous with delayed implant placement, Xenogeneic collagen matrix simultaneous with delayed implant placement
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Loss
Evaluation of 3D-printed Space Maintainers Versus Conventional Space Maintainer : a Randomized Clinical Trial
This study aims to compare the clinical evaluation and patients' satisfaction of space maintainers produced by digital workflow using the 3D-printing method (3D-SMs) versus conventional band and loop space maintainers (C-SMs)…
- Trial name
- NCT06750068
- Testing
- 3D printed space maintainer, Conventional space maintainer
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University