Clinical trials: Teeth Loss
Loss of Teeth Due to Extraction
Evaluation of Healing at Molar Extraction Sites With and Without Ridge Preservation
Following tooth extraction ridge preservation procedure have been suggested to limit bone resorptive dimensional changes to facilitate prospective implant placement.
- Trial name
- NCT02543398
- Testing
- Ridge preservation
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Periodontal Diseases, Dental Caries
A Comparison of the Accurate Diagnosis of the Horizontal & Vertical Bitewing Images
The aims of this research are to determine if vertical bitewings will be more effective and more comprehensive for the diagnosis of caries and the level of alveolar bone loss than the horizontal bitewing technique for the…
- Trial name
- NCT04341636
- Testing
- Bitewing X ray
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Implants, TNF-alpha Inhibitors
Dental Implant Healing With TNF-Alpha Inhibitors
The goal of this pilot study is to learn about healing after dental implant placement in patients taking a class of biologic drug called Tumor Necrosis Factor or TNF-alpha antagonist or inhibitor.
- Conditions
- Dental Implants, TNF-alpha Inhibitors, Edentulism
- Trial name
- NCT06538870
- Testing
- Placement of dental implants
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Unsatisfactory or Defective Restoration of Tooth
Minimal Invasive Rehabilitation of Tooth Loss in the Anterior Segment
Tooth loss can be addressed by different rehabilitative strategies. Implant-supported crowns and conventional bridges (fixed dental prostheses [FDPs]) are well established treatment alternatives.
- Trial name
- MIZE-F (NCT01997827)
- Testing
- metal-ceramic RBFDP, all-ceramic RBFDP
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Missing Teeth, Dentures
Comparison Between Conventional and CAD/CAM Complete Dentures Designed Based on Neutral Zone Concept
A within-subject cross-over study is done on eight completely edentulous patients to compare two different complete removable dentures.
- Trial name
- NCT05990088
- Testing
- Heat Cured Conventional Polymethylmethacrylate Complete Removable Dentures based on neutral zone concept, CAD/CAM Milled Methacrylate Complete Removable Dentures based on neutral zone concept.
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Immediate Implant With Bone Graft
Immediate Implant Using "Nanobone" Versus "Autogenous Bone" for Treatment of Patients With Unrestorable Single Tooth.
A successful implant therapy require appropriate hard and soft tissue, perfect implant position, appropriate alveolar ridge architecture and integration of the implant.
- Trial name
- NCT02613663
- Testing
- Immediate implants with nanobone graft, immediate implants with autogenous bone graft
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Loss
Ridge Preservation Comparing Simultaneous vs. Delayed Grafting
Comparison of the clinical healing of simultaneous vs. delayed grafting for dental implant placement.
- Trial name
- NCT03580798
- Testing
- Delayed graft, Simultaneous graft
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Tooth Loss, Bone Graft; Complications
Patient-reported Outcome Measures After Implant Placement With Contour Augmentation Procedure
Maintaining the general health and well-being of patients is the main goal of dental therapy. However, tooth extraction is indicated when teeth cannot be maintained in a status compatible with health, adequate esthetics…
- Conditions
- Tooth Loss, Bone Graft; Complications, Patient Satisfaction, Patient Acceptance of Health Care
- Trial name
- NCT05890170
- Testing
- Patient Reported Outcomes Measures
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Bern
Tooth Loss
Influence of Soft Tissue Thickness on the Bone Level Around Implants
Healthy soft tissue around the implant are considered as a biological seal to prevent inflammatory periimplant diseases and ensure healthy, stable and long-term survival of a dental implant.
- Trial name
- NCT04243460
- Testing
- Xenogeneic collagen matrix (XCM) graft augmentation, Connective tissue graft augmentation (CTG)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Medical Innovation Center Wroclaw
Tooth Loss, Recession, Gingival
Use of Leucocyte- and Platelet-rich Fibrin Membranes in Single Implant
The objective of this randomized controlled clinical trial is to evaluate the increase of soft tissue thickness around single implants installed in maxillary esthetic area with the use of Leucocyte-Platelet rich Fibrin (L-PRF)…
- Trial name
- NCT03660566
- Testing
- Test - Implant with L-PRF, Control - Implant without L-PRF
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Tooth Loss
Long- Term Follow-up of Extraction Socket Management
Twenty-nine patients needing single tooth replacement in aesthetic area were treated by extraction and socket preservation with saddle connective tissue graft between September 2009 and February 2012.
- Trial name
- NCT03410251
- Testing
- Socket preservation
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Liege
Osseodensification, Bone Expansion
Osseodensification for Narrow Alveolar Ridge Expansion
This prospective, single-arm, non-randomized interventional clinical study was designed to evaluate the immediate horizontal dimensional change in narrow alveolar ridges following osseodensification-assisted dental implant-site…
- Conditions
- Osseodensification, Bone Expansion, Alveolar Bone Loss, Jaw, Edentulous, Partially
- Trial name
- OD-RridgeExp (NCT07436533)
- Testing
- Densah burs (Osseodensification Technique)
- Where
- Yemen
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Science and Technology, Yemen
Missing Teeth
Assessment of Hard and Soft Tissue Changes Following XCM Versus FGG Simultaneous With Delayed Dental Implant Placement
Teeth loss are usually associated with alterations of extraction sockets result in obviously absorbed alveolar ridges and are often accompanied with soft tissue atrophy such as narrow keratinized tissue and a shallow vestibule.
- Trial name
- NCT07080177
- Testing
- Free gingival graft simultaneous with delayed implant placement, Xenogeneic collagen matrix simultaneous with delayed implant placement
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Missing Teeth
Zirconium Dioxide Fixed Dental Prosthesis.
The purpose of this clinical trial is to evaluate and compare bridges to replace one or two missing teeth in the mouth. The bridges will be made of two variants of ceramic material.
- Trial name
- NCT06352983
- Testing
- Fixed dental prosthesis
- Where
- 2 sites in Sweden
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Malmö University
Tooth Loss
Evaluation of 3D-printed Space Maintainers Versus Conventional Space Maintainer : a Randomized Clinical Trial
This study aims to compare the clinical evaluation and patients' satisfaction of space maintainers produced by digital workflow using the 3D-printing method (3D-SMs) versus conventional band and loop space maintainers (C-SMs)…
- Trial name
- NCT06750068
- Testing
- 3D printed space maintainer, Conventional space maintainer
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Loss, Bone Loss, Alveolar
Immediate Implant Outcomes With and Without Bone Augmentation
To evaluate immediate implant placement feasibility and esthetic outcomes in severely damaged sockets that received simultaneously bone reconstruction (cortical bone shield) and implant placement versus intact sockets that needed…
- Conditions
- Tooth Loss, Bone Loss, Alveolar, Dental Diseases, Dental Trauma
- Trial name
- NCT05157009
- Testing
- implant placement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Verdugo, Fernando, DDS
Bone Loss, Missing Teeth
The Use of Bio-Oss Collagen for Sinus Augmentation Using the Transcrestal Approach.
To assess vertical bone height gain with Geistlich Bio-Oss Collagen used in conjunction with simultaneous implant installation in transcrestal approach sinus augmentation.
- Trial name
- NCT04581304
- Testing
- Geistlich Bio-Oss® Collagen, Geistlich Bio-Oss® Granules
- Where
- Israel
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Alveolar Bone Loss
Pontic Site Development Using Soft Tissue Augmentation
in patients with vertical or horizontal defective of there ridge it is difficult to have prosthetic restoration with natural appearance emetating and simulating the adjacent abutment emergence profile so this study aims to…
- Trial name
- NCT03834649
- Testing
- partially de-epithelized connective tissue graft, Mucograft
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nouran Abdulla Mater,MD
Alveolar Bone Loss, Periodontal Diseases
Evaluation of the Effectiveness of Odontogenic Grafts Obtained From Human Teeth on Bone Formation
Tooth extraction triggers a cascade of biological events mediated by the local inflammatory response following surgical intervention and by the loss of masticatory stimulation to the periodontium.
- Conditions
- Alveolar Bone Loss, Periodontal Diseases, Periodontal Bone Loss, Periodontal Atrophy
- Trial name
- NCT07573761
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Microbial Colonization, Missing Teeth
Effect of Crown Material on Gingival Microbial Colonization
Prior approval from SOD ethical committee has been received. All patients presenting to the General OPD of School of Dentistry, Islamabad will be screened.
- Trial name
- NCT07083102
- Testing
- Experimental
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences