Clinical trials: Tear
Meniscectomy, Meniscal Tears
Needle Arthroscopy vs Conventional Arthroscopy in Knees
This is a pilot randomized controlled trial will have 54 participants. The purpose of this study is to compare two surgical techniques to determine the differences in postoperative pain and early recovery in patients between…
- Conditions
- Meniscectomy, Meniscal Tears, Meniscal Repair, Chondral Lesion of the Knee
- Trial name
- Nano (NCT07823504)
- Testing
- Needle Arthroscopy
- Volunteers
- 54 people
- Sponsor
- Panam Clinic
Partial Supraspinatus Tear, Shoulder Pain
VR-Assisted Rehabilitation in Partial Supraspinatus Tears
This randomized controlled trial investigated the effects of virtual reality-assisted rehabilitation in patients with partial supraspinatus tendon tears.
- Trial name
- NCT07478835
- Testing
- VR-assisted rehabilitation program, Conventional shoulder exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Hitit University
Calcifying Tendinitis of Shoulder
Efficacy and Tolerance of Ultrasound-guided Needling and Lavage of Calcific Tendinitis of the Rotator Cuff Performed With or Without Subacromial Corticosteroid Injection
Calcific tendinitis of the rotator cuff is a common cause of chronic pain of the shoulder. Needling and lavage of the calcification is one of the therapeutic options after failure of conservative management with physiotherapy and…
- Trial name
- CALCECHO (NCT02403856)
- Testing
- Sodium Chloride 0.9%, Methylprednisolone acetate, Ultrasound-guided Needling and Lavage
- Where
- 3 sites in France
- Volunteers
- 136 people
- Sponsor
- Nantes University Hospital
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Werewolf Flow 50 During ACL Reconstruction
The aim of this study is to compare the outcomes, ease of use, and cost of the Werewolf FLOW50 device to the institutional standard of care which is does not include the use of electrocautery devices during anterior cruciate…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Arthrofibrosis of Knee
- Trial name
- NCT04998656
- Testing
- Werewolf FLOW 50, Control
- Where
- 3 sites in United States
- Volunteers
- 182 people
- Sponsor
- University of Colorado, Denver
Anterior Cruciate Ligament Tear
Bone Marrow Aspirate Concentrate for Anterior Cruciate Ligament Tear Treatment.
A single armed multicenter study enrolling 20 patients using autologous bone marrow aspirate concentrate (which is done under local or general anesthesia to aspirate around 1-2 cc/kg body weight then concentration which is done…
- Trial name
- NCT06353503
- Testing
- autologous bone marrow aspirate concentrate
- Where
- Iraq
- Volunteers
- 20 people
- Sponsor
- abdulmajeed hammadi
Meniscal Tear
This is a Study to Verify if Marrow Venting Procedure Can Improve Meniscal Suture Healing
Meniscal suture represents the current surgical practice, and marrow venting is a low risk procedure. Bone venting may be able to improve the outcome of meniscal repair, allowing the patient a better recovery.
- Trial name
- NCT05053646
- Testing
- Meniscal repair, Marrow venting procedure
- Where
- 2 sites in Switzerland
- Volunteers
- 80 people
- Sponsor
- Christian Candrian
Meniscal Tears
Meniscal Repair Augmented With Leukocyte-Poor Platelet-Rich Plasma: A Prospective Comparative Clinical Study
This prospective, randomized, comparative clinical study will evaluate the clinical and functional outcomes of meniscal repair augmented with intraoperative intralesional leukocyte-poor platelet-rich plasma (LP-PRP) compared with…
- Trial name
- NCT07815743
- Testing
- Leukocyte-poor platelet-rich plasma, Meniscal Repair
- Where
- Mexico
- Volunteers
- 62 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Rotator Cuff Tear
Decellularized Human Placental Extracellular Matrix Tissue for Rotator Cuff Repair Augmentation
The rotator cuff is a set of muscles and tendons that help move the shoulder. Tears in the rotator cuff are common, particularly as people age. Consequently, rotator cuff repair surgeries are common, as well.
- Trial name
- ECMRCR (NCT07027735)
- Testing
- Rotator Cuff Repair with Allograft Patch, Rotator Cuff Repair with No Augmentation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Columbia University
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament (ACL) Tear
Active Noise-Cancelling Headphones With Closed-Loop Communication During Arthroscopic ACL Reconstruction
Operating room noise may interfere with communication, concentration, and surgical workflow. Active noise-cancelling (ANC) headphones can reduce background auditory distractions; however, their potential benefit during surgery…
- Conditions
- Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Injury
- Trial name
- ANC-ACL-2026 (NCT07589582)
- Testing
- Active Noise-Cancelling Headphones With Closed-Loop Communication, Standard Operating Room Communication
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Rotator Cuff Tears
MRI Evaluation of Integrity Implant for Rotator Cuff Tears
The goal of this observational study is to evaluate the effectiveness and safety of the Integrity bio-inductive implant in treating partial and full thickness rotator cuff tears.
- Trial name
- NCT06353893
- Testing
- Anika Integrity Implant System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Foundation for Orthopaedic Research and Education
Rotator Cuff Tears, Tendon Thickening
Perianchor Cyst Formation, Tendon Healing, and Clinical Outcomes Following Arthroscopic Rotator Cuff Repair
Perianchor cyst formation is frequently observed after arthroscopic rotator cuff repair; however, its clinical significance remains unclear.
- Conditions
- Rotator Cuff Tears, Tendon Thickening, Tendon Injuries, Muscle Weakness
- Trial name
- NCT07661680
- Testing
- MRI
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Rotator Cuff Tear, Rotator Cuff Tears
Post-Market Clinical Follow-up (PMCF) Study of the Pitch-Patch for the Augmentation or Reinforcement of the Rotator Cuff
This is a clinical investigation study. It will verify the long-term safety and performance of the Pitch-Patch when implanted to reinforce partially repairable rotator cuff tears and used as described by the manufacturer's…
- Conditions
- Rotator Cuff Tear, Rotator Cuff Tears, Rotator Cuff Tears of the Shoulder, Rotator Cuff Injuries
- Trial name
- NCT05906004
- Testing
- Pitch-Patch
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- Xiros Ltd
Rotator Cuff Tear, Muscle Atrophy
Stromal Vascular Fraction Cell Therapy to Improve the Repair of Rotator Cuff Tears
Rotator cuff disease is one of the most prevalent musculoskeletal conditions across the world. Patients with chronic rotator cuff tears often have substantial muscle atrophy and fatty infiltration.
- Conditions
- Rotator Cuff Tear, Muscle Atrophy, Tendon Tear
- Trial name
- NCT03332238
- Testing
- Autologous Stomal Vascular Fraction Material, Ringer's solution
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Hospital for Special Surgery, New York
Rotator Cuff Tear
Impact of BPC-157 on Recovery Following Rotator Cuff Repair Surgery
This study is a randomized, double-blind, placebo-controlled pilot trial investigating the effects of BPC-157 on tendon healing and functional recovery following arthroscopic rotator cuff repair (aRCR).
- Trial name
- NCT07803250
- Testing
- BPC-157
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arkansas
Meniscus Lesion, Meniscus Tear
Long-term Follow-up of Actifit® Meniscal Scaffold Patients.
This study will collect retrospective patient data of Actifit patients (medial and lateral, isolated cases as well as cases with concomitant procedures), including pre-op and any post-op imaging, for 120 retrospective Actifit…
- Trial name
- NCT07800923
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Orteq Sports Medicine
Osteoarthritis Shoulder, Avascular Necrosis
Perform Humeral System Study
This study is an international, single arm, multicenter, prospective, non-significant risk, Post-Market Clinical Follow-up study, which is designed to collect safety and performance data at baseline, surgery, immediate post-op…
- Conditions
- Osteoarthritis Shoulder, Avascular Necrosis, Post-traumatic Arthrosis of Other Joints, Shoulder Region, Rotator Cuff Tear Arthropathy
- Trial name
- PHS (NCT05067543)
- Testing
- Tornier Perform Humeral - Stem
- Where
- 11 sites in United States, Canada and 3 more
- Volunteers
- 300 people
- Sponsor
- Stryker Trauma and Extremities
Rotator Cuff Tear, Rotator Cuff Injury
Rotator Cuff Tendon Repair With FiberLocker System Patch Augmentation
The overall objective of this clinical investigation is to assess the safety and efficacy of full-thickness arthroscopic rotator cuff repairs augmented with the FiberLocker System for the subjects.
- Conditions
- Rotator Cuff Tear, Rotator Cuff Injury, Rotator Cuff Rupture
- Trial name
- FIBERLOCK (NCT07005063)
- Testing
- FiberLocker® System (encompassing SpeedPatch® PET and FiberLocker Instrument® SN)
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- ZuriMED Technologies AG
Anterior Cruciate Ligament Tear
A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction
This study is designed to evaluate bridge-enhanced ACL restoration (BEAR), a new surgical technique for repairing knees injured by a tear of the anterior cruciate ligament (ACL) that promotes reattachment and healing of the ACL…
- Trial name
- BEAR-MOON (NCT03776162)
- Testing
- ACL Reconstruction (Bone Patellar Tendon Bone Graft), Bridge Enhanced ACL Restoration (BEAR)
- Where
- 6 sites in United States
- Volunteers
- 150 people
- Sponsor
- The Cleveland Clinic
Osteoarthritis, Knee, Meniscus Tear
Corticosteroid Meniscectomy Randomized Trial
Synovitis has an important role in the symptoms and progression of Osteoarthritis (OA). Inflamed synovium has been associated with both increased symptoms and increased progression in OA patients.
- Conditions
- Osteoarthritis, Knee, Meniscus Tear, Meniscus; Degeneration, Synovitis
- Trial name
- CoMeT (NCT04641351)
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- The Cleveland Clinic
Massive Rotator Cuff Tear
Effects Of Biceps Transposition Without Tenotomy For Augmentation Of Massive Rotator Cuff Repairs
This prospective, single-arm interventional study will evaluate the effects of long head of the biceps tendon (LHBT) transposition without tenotomy as an augmentation technique for arthroscopic partial repair in adults with…
- Trial name
- ROTATORCUFF (NCT07375277)
- Testing
- LHBT Transposition Augmentation
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Balikesir Ataturk City Hospital