Clinical trials: Taste Perception
Healthy
Added Sugar Intake, Sweet Taste Phenotypes and Biomarkers
The goals of this cross-sectional study on a racially diverse group of children (3-10y) and their mothers are to determine whether the relationship between sweet taste phenotypes differed among mother-daughter and mother-son…
- Trial name
- SWBIO (NCT05047588)
- Where
- United States
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center
Taste Disorder, Primary, Sweet
Role of the Gut Sweet Taste Receptor in the Secretion of Glucagon-like Peptide-1 and Peptide YY
The purpose of this study is to determine the functional significance of sweet taste receptors in the secretion of GI satiation peptides by using a specific sweet taste receptor antagonist to block sweet taste perception in the…
- Trial name
- NCT01304823
- Testing
- lactisole, mixed liquid meal
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Obesity, Weight Loss
Bitter Taste and Weight Loss in Women
Individual food preferences are not considered in designing weight-loss therapies. This project will determine if short-term weight-loss is improved by matching participants with diets that reflect their genetically-determined…
- Trial name
- NCT01856660
- Testing
- Low-Carbohydrate Diet, Low-fat Diet
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Healthy
The Molecular Basis for a Broad Range of Phenotypes Related to hTAS2R38
This single-site, within-subject, experimental study is designed to test the hypothesis that individuals express taste receptors differently and have different sensitivities to bitter taste samples, which results from uneven…
- Trial name
- NCT01399944
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center
Healthy Volunteers
Effect of Choice on Food Pleasure Using fMRI
Previous studies have suggested that consumers who can choose what to eat could find food more pleasant, and consume more of that food, than when in absence of choice.
- Trial name
- PLEASIN (NCT02958371)
- Testing
- fMRI, fruit-flavored drink ingestion
- Where
- France
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Healthy
Taste Assessment Study of SHP429 in Healthy Adult Subjects
The purpose of this study is to compare the palatability of SHP429 capsule contents delivered via 3 means of administration (sprinkled on yogurt, sprinkled on applesauce, and emptied into a cup and administered with water).
- Trial name
- NCT02125292
- Testing
- Mesalamine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Shire
Roux-en-Y Bariatric Surgery
Investigation of the Effects of Obesity Surgery on Appetitive Behaviour
Among all the existing ways to treat obesity (lifestyle, pharmacological), Roux-en-Y gastric bypass (RYGB) surgery is currently the most effective.
- Trial name
- NCT02010385
- Testing
- Octreotide, Saline
- Where
- Ireland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Taste, Altered
Flavoring Oral Contrast for MR Enterography
To determine if patient satisfaction, participation, and image quality improves with flavored oral contrast for MR enterography.
- Trial name
- NCT02617576
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Bariatric Surgery Candidate, Bariatric Surgical Procedure
Fat Taste Sensory Study
Fat is the most energy dense macronutrient and consuming fat has been positively correlated to obesity. Individuals afflicted with obesity crave fat more frequently, have a higher preference for fatty taste, and consume a higher…
- Trial name
- FaTSS (NCT03540693)
- Testing
- RYGB, SG, LAGB
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Magnetic Resonance Imaging, Functional
Neural, Behavioral and Physiological Correlates of Feeding in Humans
The overarching goal of this project is to understand how nicotine addiction interacts with feeding behaviors and brain representation of food reward.
- Trial name
- NCT01665560
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Yale University
Hypogeusia
Free Fatty Acids: Short Exposure Study
This study will examine whether or not short, daily exposures change a person's ability to detect free fatty acids in a solution by its taste. Repeated exposure should improve a person's ability to detect free fatty acids.
- Trial name
- NCT01686113
- Testing
- NEFA, Sucrose
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Purdue University
Irritable Bowel Syndrome
Fecal Amino Acids，Gut Taste Receptors and Irritable Bowel Syndromes
Clinical data, fresh feces and intestinal mucosal tissues of patients with diarrheal IBS were collected. High performance liquid chromatography, immunohistochemistry and immunofluorescence were used to study the amino acid levels…
- Trial name
- NCT06489444
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Appetite and General Nutritional Disorders, Hormone Replacement
Sweet Taste Receptors and the Secretion of Glucagon-like Peptide-1 and Peptide YY
The purpose of this study is to determine the functional significance of sweet taste receptors in the secretion of GI satiety peptides by using a specific sweet taste receptor antagonist to block sweet taste perception in the gut.
- Trial name
- NCT01088841
- Testing
- lactisole
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
HIV in Adults
Taste Properties of Atazanavir and Cobicistat
The primary objective is to assess the taste properties of atazanavir (ATV) and cobicistat (COBI) alone and in combination as well as oral test formulations containing both ATV and COBI.
- Trial name
- NCT02307656
- Testing
- Atazanavir, Cobicistat, Active Pharmaceutical Ingredient
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Cancer
Sensory Approach of Food Modifications Led by Chemotherapy
The aim of the present study was to evaluate the impact of chemotherapy on sensorial perception in lung cancer patients in comparison to a control group (individuals without lung cancer and chemotherapy treatment).
- Trial name
- ARC-1 (NCT02368509)
- Testing
- Perform sensory tests
- Where
- 3 sites in France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Fat Taste
Food Composition and Palatability
This study will investigate fat taste and if free fatty acids (FFA) in food function as a signal for fat content. FFA are quite unpleasant - the investigators want to measure if the concentration in different foods correlates…
- Trial name
- FCandP (NCT02357329)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Purdue University
Taste Sensitivity, Umami Taste Perception
Umami Taste Intensity and Meal Intake
Sweet and salty tastes can influence food intake. Increased intensity of these tastes has been shown to decrease food intake and increase satiation compared to the less intense taste, independent of palatability.
- Conditions
- Taste Sensitivity, Umami Taste Perception, Food Intake Regulation, Hedonic Function
- Trial name
- OptUmami (NCT07421466)
- Testing
- Hedonic mapping, Ad libitum risotto test meal
- Where
- Netherlands
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Taste Sensitivity, Fatty Acid Type
Fatty Acid Taste Thresholds: Caproic, Lauric, Oleic, Linoleic, Linolenic
Differences in human oral sensitivity for caproic, lauric, oleic, linoleic, and linolenic acids will be explored. Prior work indicates that there may be a learning effect in measuring detection thresholds for free fatty acids.
- Trial name
- NCT01996566
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Purdue University
COVID-19, Anosmia
Finding Out if COVID-19 Infection Can be pREdicted by ChAnges in Smell and/or Taste
The FORECAST Study is an observational cohort study looking at two cohorts of patients presenting with COVID-19: a general public cohort, aiming to investigate if new loss or reduced sense of smell and/or taste are early signs of…
- Trial name
- FORECAST (NCT04377815)
- Testing
- General Public cohort
- Where
- 2 sites in United Kingdom
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- University College, London
Healthy
Sensory Evaluation of the Taste of Pediatric Medicines
The investigators will conduct a systematic study of the sensory perception of a diverse set of commonly used pediatric liquid medications and excipients in tandem with an equally complete genetic analysis of the adult sensory…
- Trial name
- MEDTASTE (NCT03627351)
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center