Clinical trials: Target-controlled Infusion
Anesthesia Brain Monitor, Sufentanil
Effects of Sufentanil Target Controlled Infusion on Patient State Index Values and Electroencephalographic Spectrum During Total Intravenous Anesthesia With Propofol
Sufentanil Target Controlled infusion (TCI, Gepts model) effects on Neuromonitoring during Total Intravenous Anesthesia (TIVA) with Propofol TCI (Eleveld model) has not been investigate yet.
- Conditions
- Anesthesia Brain Monitor, Sufentanil, Target Controlled Infusion
- Trial name
- NCT06388408
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Padova
Liver Transplant Recipients
Effect of TCI Propofol on Liver Transplant (TCI) Propofol on Intra-operative Usage of Vasopressors in Liver Transplant Recipients.
Both isoflurane and propofol are being used to give anaesthesia for living donor liver transplant in our institute. Propofol when compared to isoflurane has advantages like early awakening from anaesthesia, reduced nausea…
- Trial name
- NCT06418893
- Testing
- Target control infusion propofol, Inhalational isoflurane
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Anesthesia, Pain
Surgical Pleth Index (SPI) Versus Standard Clinical Approach Analgesia
The study is aimed at confronting a surgical pleth index based protocol for intraoperative analgesia in a desflurane based general anesthesia for thyroidectomy, versus a standard clinical approach.
- Conditions
- Anesthesia, Pain, Surgery
- Trial name
- SPIDER (NCT03218306)
- Testing
- Surgical Pleth Index, Clinical guidance
- Where
- Italy
- Volunteers
- 198 people
- Sponsor
- University of Cagliari
Bladder Tumors, Spinal Anesthesia
Magnesium vs. Dexmedetomidine in TURBT Under Spinal Anesthesia
This randomized controlled trial evaluated the effects of intraoperative intravenous magnesium sulfate versus dexmedetomidine on postoperative pain, analgesic consumption, hemodynamic stability, and respiratory function in…
- Conditions
- Bladder Tumors, Spinal Anesthesia, Postoperative Pain, Magnesium Sulfate
- Trial name
- TURBT (NCT07445451)
- Testing
- magnesium sulfate, Dexmedetomidine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Anesthesia
Use of Closed-loop Anesthesia in Pediatric Patients
To compare manual administration of propofol and remifentanil and dual closed-loop using bispectral index as the control variable during pediatric anesthesia
- Trial name
- LoopPed (NCT00778505)
- Testing
- Propofol, remifentanil
- Where
- 2 sites in France
- Volunteers
- 45 people
- Sponsor
- Hopital Foch
Pain, Tachycardia
Usefulness and Predictive Capacity of ANI and SPI of the Hemodynamic Response
The primary objective of this study is to investigate the influence of a standardized noxious stimulus on the ANI, SPI and hemodynamic parameters during standard propofol and sufentanil TCI and to see if the ANI and SPI are…
- Conditions
- Pain, Tachycardia, Hypertension
- Trial name
- NCT02608775
- Testing
- Metrodoloris Medical System, Aisys® care station, Acertys
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitair Ziekenhuis Brussel
Anesthesia Brain Monitoring
Describe Relations Between qCON and qNOX Indicies During Propofol-Remifentanil General Anesthesia
CONOX is a neuromonitoring EEG- device for sedation (qCON) and analgesia (qNOX) monitoring during general anesthesia. It is unknown on how the indicies can differentiate themselves so aim of this study is to determine the…
- Trial name
- NCT06349681
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- University of Padova
Laryngismus
Laryngeal Mask Airway (LMA) Insertion With Sevoflurane and Remifentanil
The purpose of this study was to determine the most suitable effect-site concentration of remifentanil for the LMA insertion during inhaled induction with 8% sevoflurane in adults.
- Trial name
- NCT01456299
- Testing
- Remifentanil 1, Control, Remifentanil 2
- Where
- South Korea
- Volunteers
- 102 people
- Sponsor
- Gachon University Gil Medical Center
Children, Hernia, Inguinal
Comparing Inhalation and Total Intravenous Anesthesia Methods
This study compares the effects of anesthesia using target-controlled infusion (TCI) and inhalation methods on pediatric patients undergoing inguinal hernia repair.
- Trial name
- TIVA-IHA (NCT06467279)
- Testing
- Target Controlled İnfusion, Inhalation anesthetic
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Scheduled Laparoscopic Surgery
Pupillary Reflex Measurement to Guide Intraoperative Analgesia During Laparoscopic Surgery
The purpose of this study is to determine whether analgesia guided by pupillary reflex during laparoscopic surgery is effective in opioid sparing (intraoperative remifentanil and postoperative morphine).This is a prospective…
- Trial name
- NCT02116868
- Testing
- Pupillometry guided analgesia (PP), Tailored remifentanil controlled infusion, Tailored antihypertensive drug administration
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
General Anesthesia, Propofol Target-controlled Infusion
Effects of Epidural Local Anesthetics on Propofol Induction
The investigators designed a prospective, randomized, placebo-controlled study to determine whether thoracic epidural anesthesia(TEA) with different local anesthetics has different influences on the propofol dose during induction.
- Conditions
- General Anesthesia, Propofol Target-controlled Infusion, Thoracic Epidural Anesthesia
- Trial name
- NCT02000973
- Testing
- Lidocaine, Bupivacaine, Ropivacaine
- Volunteers
- 80 people
- Sponsor
- First Hospital of China Medical University
Elective Surgery, Target Controlled Infusion (TCI)
EC50 of Ciprofol Combined With Remifentanil for Inhibiting Tracheal Responses in Patients Undergoing Gynecological Surgery: a Two-phase Up-and-down Sequential Allocation Study
1. The combined induction of intubation with propofol and remifentanil is widely used in clinical anesthesia, primarily through a single intravenous injection.
- Conditions
- Elective Surgery, Target Controlled Infusion (TCI), Noxious Stimuli, Tracheal Intubation Stimulation
- Trial name
- EC50 via TCI (NCT07462949)
- Testing
- Cipofol combined with remifentanil administered via target-controlled infusion
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Anesthesia Brain Monitoring, Lidocaine
Effects of Lidocaine Bolus and Infusion on Bispectral Index Values and Spectrum During Anesthesia Maintenance
Lidocaine has been shown to increase the hypnotic effects of Propofol, however no trials shows the effects on Bispectral Index Values (BIS) and spectral analysis during total intravenous anesthesia maintenance delivered with…
- Trial name
- NCT06135688
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Padova
Spine Diseases
Awakening in Spine Surgery: A Comparison Between Clinical Signs and Bispectral Index
BIS is one of several equipments used to monitor depth of anesthesia.Some studies found BIS can reduce total propofol dose when being used with target controlled infusion (TCI).The objective is to compare awakening time after…
- Trial name
- NCT02174913
- Testing
- bispectral index, Target controlled infusion of propofol, Fentanyl
- Where
- Thailand
- Volunteers
- 34 people
- Sponsor
- Mahidol University
Colonoscopy
Sedation Techniques for Outpatient Colonoscopy
This was a prospective, randomized, single-blind controlled clinical trial comparing three sedative regimens for outpatient colonoscopy.
- Trial name
- NCT04686058
- Testing
- Propofol 10 MG/ML Injection, Midazolam injection, Pethidine Hydrochloride 50 Mg/mL Solution for Injection
- Where
- Malaysia
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Propofol Target-controlled Infusion, Desflurane
Effect of Desflurane v/s Propofol on the Optic Nerve Sheath Diameter
effect of propofol vs desflurane on ONSD
- Conditions
- Propofol Target-controlled Infusion, Desflurane, Optic Nerve Sheath Diameter
- Trial name
- ONSD (NCT07359508)
- Testing
- Desflurane, Propofol (Group P)
- Where
- India
- Volunteers
- 146 people
- Sponsor
- All India Institute of Medical Sciences
Tooth Extractions
Comparison of Sufentanil and Remifentanil Infusion During General Anaesthesia for Removal of Wisdom Teeth in Ambulatory Surgery
Wisdom teeth removal under general anaesthesia is usually suitable for ambulatory surgery. The choice of opioid in dental day surgery is based on the need for a rapid and full recovery, as well as less morphine administration.
- Trial name
- SUF-REM-DDS (NCT01139671)
- Testing
- Remifentanil
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Clermont-Ferrand
Morbid Obesity
Remifentanil Dosing Regimes for Anesthesia in Bariatric Surgery: Characteristics of Early Recovery
Early recovery characteristics are important for patients' safety and operating room turnover. Our aim was to compare fundamental methods for dosing remifentanil during morbid obesity surgeries: a manual infusion and a…
- Trial name
- NCT04690088
- Where
- Lithuania
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Anesthesia
Dexmedetomidine and Desflurane Consumption
The aim of this study is to calculate desflurane consumption when combined with intraoperative dexmedetomidine infusion guided by bispectral index (BIS)
- Trial name
- NCT02652312
- Testing
- Dexmedetomidine, Ondansetron, fentanyl
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Theodor Bilharz Research Institute
Postoperative Delirium (POD), Postoperative Pain
Comparison of Target-Controlled and Manual Total Intravenous Anesthesia in Supratentorial Surgery
This study aims to investigate the effect of target-controlled infusion using the Eleveld pharmacokinetic model compared with manually controlled total intravenous anesthesia on the incidence of postoperative delirium in patients…
- Conditions
- Postoperative Delirium (POD), Postoperative Pain, PONV, Burst Suppression
- Trial name
- NCT07357480
- Testing
- Target Controlled Infusion, Total Intravenous Anesthesia(TIVA)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Istanbul University - Cerrahpasa