Clinical trials: TSH
Pregnancy Related, Thyroid
Safety and Efficacy of Empiric Levothyroxine (LT4) Dose Increase Versus Individualized LT4 Dose Increase in Hypothyroid Women During Pregnancy
In women who require thyroid hormone replacement medication, the investigators will compare 2 ways to adjust thyroid medication during pregnancy to determine superiority in maintaining optimal blood levels of thyroid hormone.
- Trial name
- NCT03115515
- Testing
- levothyroxine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Exercise, Thyroid Function
Thyroid Hormone Responses to Repeated Wingate Exercise Versus a Non-Exercising Comparison Group
This two-group, non-randomized study investigated the acute effects of repeated Wingate exercise on free thyroid hormone concentrations in male amateur soccer players.
- Trial name
- RWT-THYROID (NCT07765290)
- Testing
- Repeated Wingate Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Inonu University
Recurrent Pregnancy Loss
Recurrent Pregnancy Loss and Thyroid Disease
The present study is divided into two groups ,one is the patients with subclinical hypothyroidism who has TPO antibody positive women with TSH concentrations > 2.5 mU/L and below the upper limit of the pregnancy specific…
- Trial name
- NCT03106935
- Testing
- Levothyroxine
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Soochow University
Healthy
Cardiopulmonary Capacity in Elderly With Different Ranges of Serum Thyroid Stimulating Hormone
The purpose of this study is to correlate in an elderly population (≥ 65 years), the different levels of serum TSH, with cardiopulmonary capacity, quality of life, depressive symptoms and cognition.
- Trial name
- NCT01849861
- Testing
- Methimazole
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Thyroid Cancer Patients
Effect of Carum Carvi on Thyroid Hormones and TSH Level
Carum Carvi has been frequently used in traditional medicine for a variety of disease ranging from dyspepsia to Alzheimer's disease.We observed high TSH levels in few patients with thyroid cancer who receiving Carum Carvi despite…
- Trial name
- NCT01471288
- Testing
- Carum Cravi
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Iodine Deficiency, Subclinical Hypothyroidism
Iodine Supplementation in Obesity
The study hypothesis is that iodine supplementation will lower serum TSH and leptin concentrations and thereby improve the lipid and glucose profile.
- Trial name
- NCT01985204
- Testing
- Iodine tablet
- Where
- 2 sites in Morocco
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Hashimoto Disease, Treatment Levothyroxine
Effect of Treatment for Vitamin D Deficiency on Thyroid Function and Autoimmunity in Hashimoto's Thyroiditis.
The objective of this study is to evaluate the effect of vitamin D supplementation on thyroid autoimmunity, thyroid function, and other metabolic and clinical variables associated with the thyroid axis in patients with…
- Conditions
- Hashimoto Disease, Treatment Levothyroxine, Vitamin D Deficiency
- Trial name
- NCT04778865
- Testing
- Vitamin D-correction, Vitamin D-RDA
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Malignant Neoplasm of Thyroid, Heart Diseases
Thyrotropin Over-suppression and Heart
The investigators evaluated the cardiac effects of Thyroid-stimulating hormone (TSH) over-suppression in women with differentiated thyroid cancer (DTC) frequently encountered during suppression therapy.
- Conditions
- Malignant Neoplasm of Thyroid, Heart Diseases, Thyrotoxicosis on Thyroxine Therapy
- Trial name
- NCT02645786
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Chuncheon Sacred Heart Hospital
Sub-clinical Hypothyroidism, Hypothyroidism
Validation of a New TSH Test
The aim of this research project, which is realised with the partnership of the enterprise Siamed'Xpress (Marseille), is to validate a new TSH diagnostic test in vitro, to allow an earlier screening of hypothyroidism.
- Conditions
- Sub-clinical Hypothyroidism, Hypothyroidism, Euthyroidism
- Trial name
- NCT01997554
- Testing
- Blood sample
- Where
- 2 sites in France
- Volunteers
- 1,654 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Transient Hypothyroxinemia
Thyroid Function in Late Preterm Infants
Transient hypothyroxinemia (TH) is a condition characterized by low levels of serum thyroxine (T4) and normal levels of thyroid stimulating hormone (TSH).
- Trial name
- NCT00971555
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Congenital Hypothyroidism, Hypothyroidism
Generic vs. Name-Brand Levothyroxine
This study compares two different brands of thyroxine (thyroid hormone). Currently, pharmacists may be substituting generic formulations of thyroid hormone without your doctor knowing about this.
- Trial name
- NCT00403390
- Testing
- Brand Name Levothyroxine (Synthroid), Generic formulation of Levothyroxine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Healthy
BE of Euthyrox® Tablets (Merck Nantong Versus Merck Darmstadt Sites)
The purpose of this study is to demonstrate bioequivalence (BE) between Euthyrox® tablets manufactured at Merck Nantong (Test Euthyrox) versus the tablets manufactured at Merck Darmstadt (Reference Euthyrox).
- Trial name
- NCT05174000
- Testing
- Test Euthyrox®, Reference Euthyrox®
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Thyroid Function
Mothers and Babies at Yorkhill Thyroid Health Cohort
This is an observational study in pregnant mothers and their newborn babies. The rationale of the study is to examine early markers of the effects of iodine insufficiency during pregnancy on thyroid stimulating hormone (TSH) and…
- Trial name
- MABY (NCT02390128)
- Testing
- observational only
- Where
- United Kingdom
- Volunteers
- 697 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Diabetes Mellitus, Diabetic Retinopathy
Serum GPER-1 and Oxidant/Antioxidant Levels on Retinopathy in Diabetic Patients
Observational, comparative, cross-sectional study
- Conditions
- Diabetes Mellitus, Diabetic Retinopathy, Hormones
- Trial name
- NCT04930224
- Testing
- The effect of GPER-1 on the formation of diabetic retinopathy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Metabolic Syndrome, Thyroid Nodule
Relationship of Metabolic Syndrome and Its Components With Thyroid Nodule(s)
To investigate the association between metabolic syndrome (MS) and thyroid nodule(s).
- Trial name
- NCT03009279
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Lin Liao
Thyroid, Thyroid Dysfunction
Upper Limit for TSH of First and Second Trimester Pregnancy in Turkey
Physiological changes necessitate the use of pregnancy-specific reference ranges for TSH and FT4 to diagnose thyroid dysfunction during pregnancy.
- Conditions
- Thyroid, Thyroid Dysfunction, Hypothyroidism, Pregnancy Early
- Trial name
- NCT03754621
- Testing
- Serum thyroid functions tests
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Bartin State Hospital
Benign Nontoxic and Toxic Goiter, Graves' Disease
rhTSH, Thyroid Size, and Radioiodine Therapy in Benign Goiter
The trials in this protocol deals with the effect of pretreatment with rhTSH on radioiodine treatment of thyroid size and function, in patients with nontoxic and toxic nodular goiter.
- Trial name
- NCT00145366
- Testing
- Recombinant human thyrotropin (Thyrogen)
- Where
- Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Cognitive Impairment
Cognitive Functions During Thyrotropin Suppressive Therapy in Patients With Differentiated Thyroid Carcinoma
Thyroid carcinoma is the common endocrine system malignant neoplasm. At present it has become the malignant neoplasm of fastest growing incidence rate. More than 90% thyroid carcinoma is thyroid differentiated carcinoma（DTC）.
- Trial name
- NCT02665325
- Testing
- TSH-suppressive therapy
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Inner Mongolia Medical University
Infertility, Female
Association Between Serum Thyroid-stimulating Hormone (TSH) and Intracytoplasmic Sperm Injection (ICSI) Outcome in Women Undergoing ICSI
TSH has been suggested to be involved in reproductive challenges such as ovulatory issues, infertility, miscarriage, and maternal complications for many years.
- Trial name
- NCT07449260
- Testing
- Basal TSH level
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Cairo University