Clinical trials: TMS
Cerebral Palsy, Spasticity
Spinal Cord Stimulation for Children With Cerebral Palsy
The goal of this clinical trial is to help understand spinal cord excitability in children with cerebral palsy compared to neurologically typical children.
- Trial name
- NCT07516067
- Testing
- Transcutaneous Spinal Cord Stimulation (tSCS)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Martin Piazza
Autism Spectrum Disorder
Transcranial Magnetic Stimulation (TMS) Study for Adults With Autism Spectrum Disorder (ASD)
This is a randomized interventional study designed to evaluate the effects of repetitive Transcranial Magnetic Stimulation (rTMS) on neural and behavioral facets of social cognition in adults with autism spectrum disorder (ASD).
- Trial name
- NCT04936009
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yale University
Transcranial Magnetic Stimulation, Drug Resistant Epilepsy
The Mechanism of cTBS Targeting Dentate Nucleus for DRE
In our previous cross-over study--the continuous θ burst stimulation (cTBS) targeting cerebellum dentate nucleus of 44 drug-refractory epilepsy (DRE) patients, a significant reduction in seizure frequency was observed.
- Conditions
- Transcranial Magnetic Stimulation, Drug Resistant Epilepsy, Cerebellum
- Trial name
- NCT05809349
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Multiple Sclerosis, Weakness
Effects of the Cross-Training in Patients With Multiple Sclerosis
The purpose of this study is to determine whether, in patients with multiple sclerosis presenting with marked asymmetry of strength, training the less-affected limb with a Cross-Training approach may induce a meaningful transfer…
- Conditions
- Multiple Sclerosis, Weakness, Fatigue
- Trial name
- CTSM (NCT02010398)
- Testing
- Cross-Training healthy subjects, Cross-Training multiple sclerosis, Standard-training multiple sclerosis
- Where
- 3 sites in Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Brain Concussion, Mild Traumatic Brain Injury
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
This study aims to examine the long-term effect of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, on chronic headaches following mild traumatic brain injury (mTBI).
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury, Headache, Post-Concussion Symptoms
- Trial name
- NCT06112093
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Healthy
Brain Control of Blinking
This study will use transcranial magnetic stimulation (TMS) to study how the brain controls movement of muscles in the face-in particular, those involved in eye blinking.
- Trial name
- NCT00030199
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Chronic Tinnitus
rTMS for the Treatment of Chronic Tinnitus: Optimization by Simulation of the Cortical Tinnitus Network
Transcranial Magnetic Stimulation is used to modulate both the auditory and non-auditory neural pathways contributing to the perception of phantom sounds.
- Trial name
- Multisite rTMS (NCT01663324)
- Testing
- rTMS intervention 1, rTMS intervention 2
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Regensburg
Healthy
Real-time Monitoring of Motor Cortical Activity Induced by Low-frequency Repetitive Transcranial Magnetic Stimulation
In this study, we investigated the effect of low-frequency repetitive trans cranial magnetic stimulation, one of the noninvasive brain stimuli, on the functional changes of the bilateral motor cortical activity in normal subjects…
- Trial name
- NCT04019028
- Testing
- low frequency rTMS + Navigation System, only low frequency rTMS
- Where
- South Korea
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Stress, Healthy
rTMS of Limbic Circuitry in Stress Modulation in Healthy Volunteers
This study will be conducted with healthy male and female participants. Aim 1 will determine during sham repetitive transcranial magnetic stimulation (rTMS) how a drug stressor combination (yohimbine + hydrocortisone) relative to…
- Trial name
- TSM-1 (NCT04180969)
- Testing
- yohimbine + hydrocortisone, medial prefrontal cortex rTMS
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wayne State University
Motor Cortex, Motor Skills
Developing and Optimizing Transcranial Magnetic Stimulation for Motor Rehabilitation
This study aims to evaluate three different transcranial magnetic stimulation protocols and their impact on motor system neurophysiology and skill learning.
- Trial name
- NCT05861284
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Elisa Kallioniemi
Healthy Adult
Exploring the Modulatory Role of Brain State on the Prefrontal Response to Excitatory Stimulation
Therapeutic repetitive transcranial magnetic stimulation (rTMS) for depression is well-supported, with multiple protocols approved by the United States Food and Drug Administration and global efforts aimed at boosting its…
- Trial name
- NCT06750614
- Testing
- intermittent theta-burst stimulation (iTBS)
- Where
- Hong Kong
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Depressive Syndrom
Real-World NeuroModulate: Investigating Non-Invasive Brain Stimulation for Neuropsychiatric Disorders at TUM
In this study, patients diagnosed with a depressive syndrome and with a clinical indication for treatment will receive an acute course of transcranial magnetic stimulation (TMS).
- Trial name
- NCT07420322
- Testing
- iTBS Treatment
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Parkinson's Disease
Effects of RAC With Locomotion Training on Cortical Excitability and Behavior in Patients With PD
In this study, 51 subjects include 17 freezers,17 non-freezers and 17 aged-matched healthy subjects will be recruited. We will compare the cortical excitability, gait performance, and stepping-in-place performance before and…
- Trial name
- NCT03656796
- Testing
- Treadmill training with auditory cues, Treadmill training without auditory cues
- Where
- Taiwan
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Low Back Pain
Corticospinal and Motor Behavior Responses After Physical Therapy Intervention in Patients With Chronic Low Back Pain.
This study aims to 1) determine the immediate effects of transcranial direct current stimulation (tDCS) on corticospinal excitability, lumbar multifidus muscle (LM) activation, as well as lumbar stability in patients with chronic…
- Trial name
- NCT05156242
- Testing
- Active-tDCS priming MCE, NMES priming MCE, Conventional physical therapy
- Where
- Thailand
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Autistic Disorder
A Chart Review to Evaluate the Safety and Efficacy of MeRT on Subjects With ASD
The purpose of this study is to evaluate the safety and efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) on subjects with Autism Spectrum Disorder (ASD).
- Trial name
- NCT02758496
- Testing
- MeRT Efficacy Chart Review
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Wave Neuroscience
Healthy
Theta Burst Transcranial Magnetic Stimulation of Fronto-parietal Networks: Modulation by Mental State
The purpose of this study is to improve understanding of the way transcranial magnetic stimulation (TMS), a form of non-invasive brain stimulation, affects the brain.
- Trial name
- TMScogMod (NCT04010461)
- Testing
- TMS, n-back working memory task
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Healthy Adults
Efficacy and Safety of Repetitive Transcranial Magnetic Stimulation and Expressive Writing for Post-Traumatic Stress
The goal of this clinical trial is to learn if a combined treatment using repetitive transcranial magnetic stimulation (rTMS) and expressive writing works to reduce symptoms of post-traumatic stress in adults.
- Trial name
- NCT07567261
- Testing
- Repetitive Transcranial Magnetic Stimulation, Expressive writing
- Where
- 2 sites in Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Servicio Canario de Salud
Healthy, Healthy Adult
Effects of Repetitive Transcranial Magnetic Stimulation on Two Cerebellar Targets
The purpose of this study is to understand how different areas of the cerebellum (a part of the brain) control different functions and how they can be influenced by non-invasive brain stimulation.
- Trial name
- StimCervelet (NCT07561229)
- Testing
- Active rTMS - Lobule VIII, Active rTMS - Crus I/II, Cognitive and Motor Assessment Battery
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Patellofemoral Pain Syndrome
Central Neuromuscular Dysfunction in Patellofemoral Pain
Patellofemoral joint problems constitute a significant portion of knee pain and injuries. Patellofemoral pain, which is among these problems, is a common musculoskeletal disorder with a poor long-term prognosis in the community.
- Trial name
- NCT05561153
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
GABAergic System
Association Between Serum and Neuroimaging Measurements of the GABAergic System
The goal of this study is to better understand the relationship between peripheral and central nervous system measurements of the gamma-aminobutyric acid (GABA) system in otherwise healthy individuals.
- Trial name
- NCT06464172
- Testing
- Acute Oral gamma-aminobutyric acid (Natural Health Product in Canada)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Francois Corbin