Clinical trials: Symptomatic Irreversible Pulpitis
Symptomatic Irreversible Pulpitis
Effect of Ultrasonic Activation of Bioceramic Sealer on Postoperative Pain in Lower Premolars
The aim of this study is to clinically compare post-operative pain levels after ultrasonic activation of Ceraseal bioceramic sealer versus non-activated bioceramic sealer for patients with symptomatic irreversible pulpitis…
- Trial name
- NCT05289791
- Testing
- ultrasonic activation of bioceramic sealer
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endodontically Treated Teeth
Outcome of NSRCT Versus VPT in Management of Teeth with Symptomatic Irreversible Pulpitis Associated with Apical Periodontitis
Pulpitis is the pulpal inflammation in response to irritants which are either microbial, chemical, or physical (mechanical and thermal) in origin.
- Trial name
- NCT06226870
- Testing
- root canal tretment, biodentin VPT, PRF
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Minia University
Irreversible Pulpitis
The Effect of Intra-pulpal Anesthesia With Cryotherapy on Intra-operative Pain
The goal of this clinical trial is to compare the effect of cooling of local anesthesia on intraoperative pain during root canal treatment in mandibular molars diagnosed as symptomatic irreversible pulpitis.
- Trial name
- NCT06194721
- Testing
- Cold intrapulpal anesthesia, Room temperature intrapulpal anesthesia
- Where
- United Arab Emirates
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Irreversible Pulpitis
the Effect of Preoperative Sodium Ibuprofen on Postoperative Endodontic Pain
The aim of this study is to clinically compare post-operative pain levels after administration of preoperative single dose of sodium ibuprofen versus placebo for patient with symptomatic irreversible pulpitis related to…
- Trial name
- NCT04964622
- Testing
- nurofen
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis
Celebrex Premedication in Teeth With Symptomatic Irreversible Pulpitis
Assessing the efficacy of Celebrex premedication on pain during and after endodontic treatment in teeth with symptomatic irreversible pulpits
- Trial name
- NCT03339544
- Testing
- Celebrex premedication
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endodontic Disease, Endodontically Treated Teeth
Effect of Different Modalities of Cryotherapy on Post-Operative Pain in Patients With Symptomatic Irreversible Pulpitis
Problem statement: The post-operative pain after endodontic treatment. aim of study: The study is aiming to compare postoperative pain after submucosal cold saline injection (submucosal cryotherapy) (SMC) versus intra-canal…
- Trial name
- NCT06304259
- Testing
- Saline
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- October 6 University
Symptomatic Irreversible Pulpitis
Assessment of Local Anaesthesia Effectiveness in Symptomatic Irreversible Pulpitis
This study aims to evaluate the comparative efficacy of two different local anaesthetic agents for supplemental buccal infiltration after a failed inferior alveolar nerve block in achieving profound pulpal anaesthesia for…
- Trial name
- LA AGENTS (NCT06862570)
- Testing
- 2% lignocaine with epinephrine 1.8 ml(36mg/ml lignocaine HCL, epinephrine bitartrate 0.0324mg/ml), 4% Articaine with epinephrine 1.7 ml (40mg/ml Articaine HCL, epinephrine bitartrate 0.018 mg/ml)
- Where
- Pakistan
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- 28 Military Dental Centre Lahore
Pulpitis
Comparative Evaluation of Pulpal Anaesthetic Efficacy of Different Anaesthetic Solutions for Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis
Pulpal and periapical inflammation and infection can cause tissue pH in the affected region to be lowered which results in less penetration of anesthetic solution in the nerve membrane and hence delays the onset of anesthesia.
- Trial name
- NCT05239078
- Testing
- local anaesthetic injection
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dr. Vivek Aggarwal
Pulpitis - Irreversible
Effect of Cryotherapy on Postoperative Pain for Pulpotomy
The goal of this clinical trial is to investigate the effect of cryotherapy on post-operative pain for pulpotomny in permanent mature carious posterior teeth with symptomatic irreversible pulpitis.
- Trial name
- NCT07245004
- Testing
- Cryotherapy
- Where
- Thailand
- Volunteers
- 82 people
- Sponsor
- Sirawut Hiran-us
Pulpitis - Irreversible
A-prf,Nanochitosan Combined With A-prf Compared to Chitosan for Symptomatic Irreversible Pulpitis of Mature Teeth
Clinical and radiographic assessment of A-prf,A-prf combined with nanochitosan compared to chitosan for symptomatic irreversible pulpits in lower permanent first molar
- Trial name
- NCT06438523
- Testing
- PULPOTOMY OF MATURE PERMENANT TEETH
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Pulpitis - Irreversible, Anesthesia, Local
Effect of Preoperative Diclofenac Potassium on Articaine Buccal Infitration Success
The purpose of this study is to assess the effect of preoperative Diclofenac Potassium (50 mg Cataflam) on the anesthetic success of buccal infiltration with 4% articaine with epinephrine 1:200,000 in mandibular molars with…
- Trial name
- NCT03174860
- Testing
- Diclofenac Potassium 50mg Tab
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Pulpitis - Irreversible
Comparison Between Intraligamentary Piroxicam and Articaine
Comparing the efficacy of intra-ligamentary Piroxicam and intra-ligamentary Articaine on pain during and after endodontic treatment of mandibular molars with symptomatic irreversible pulpitis.
- Trial name
- NCT03612323
- Testing
- Intra-ligamentary Piroxicam, Intra-ligamentary Articaine
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
Comparison of Post-Operative Pain Occurrence After Single Visit Root Canal Treatment
The goal of this clinical trial is to compare the post-operative pain occurrence after single visit root canal treatment using Two NiTi Rotary Files.
- Trial name
- NCT06777381
- Testing
- single visit root canal treatment using ProTaper Universal rotary system, single visit root canal treatment using M-Pro rotary system
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- National Research Centre, Egypt
Failed Mechanical Induction
Efficacy of Two Injection Techniques on Success Rate of Inferior Alveolar Nerve Anesthesia
Forty healthy patients with including criteria who failed to infra alveolar nerve block injection (without lip numbness) have been randomly divided into two groups on a random basis and have received Gow-Gates or another inferior…
- Trial name
- NCT02543619
- Testing
- Injection technique
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences
Symptomatic Irreversible Pulpitis
Preoperative Dexamethasone Injection to Improve Local Anesthesia Success in Endodontic Treatment
This study aims to determine whether giving a single dose of 4mg dexamethasone before root canal treatment can reduce the amount of pain patients experience during the procedure .
- Trial name
- DILAS (NCT07699315)
- Testing
- dexamethasone, Saline (0.9% NaCl)
- Volunteers
- 60 people
- Sponsor
- Watim Medical & Dental College
Pulpitis - Irreversible
Enhancing Anaesthetic Success in Mandibular Molars With Symptomatic Irreversible Pulpitis: A Comparative Randomized Controlled Trial
The goal of this clinical trial is to assess the effect of Preoperative intraligamentary corticosteroids injection Cryotherapy which is cold application on : Hard tooth structure ( crown of the tooth ) Soft tissue overlying roots…
- Trial name
- NCT06330519
- Testing
- Dexamethasone sodium phosphate injection, 1,1,1,2 tetrafluoroethane, intraoral soft tissue cryotherapy
- Where
- Egypt
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pulpitis - Irreversible
Comparison of a Prophylactic Intraligamentary Injection of Piroxicam Versus Mepecaine of Post-endodontic Pain
to evaluate the effect of a single intraligamentary injection of piroxicam on postoperative pain associated with endodontic procedures.
- Trial name
- NCT03006107
- Testing
- intraligamentary injection piroxicam, Intraligamentary mepevacaine
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
Effect of Alcohol Consumption on the Success Rates
This prospective, randomized, double-blind clinical trial will be carried out Conservative Dentistry, Faculty of Dentistry, Jamia Millia Islamia.
- Trial name
- NCT06201871
- Testing
- Lidocaine Hydrochloride
- Where
- India
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Jamia Millia Islamia
Irreversible Pulpitis, Symptomatic Irreversible Pulpitis
To COMPARE the EFFECT of TWO INSTRUMENTATION TECHNIQUES on the INCIDENCE of POST-ENDODONTIC PAIN in PATIENTS UNDERGOING ROOT CANAL TREATMENT in TEETH with IRREVERSIBLE PULPITIS
The aim of this study is to compare the post endodontic pain in patients presenting with irreversible pulpitis and undergoing root canal treatment with two techniques.
- Conditions
- Irreversible Pulpitis, Symptomatic Irreversible Pulpitis, Asymptomatic Irreversible Pulpitis
- Trial name
- NCT06842251
- Testing
- Rotary Crown Down Technique, Manual Step Back Technique
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Urooj Fatima
Post Operative Pain After Root Canal Therapy
Postoperative Pain Comparison of Two Root Canal Sealers in Irreversible Pulpitis
This study, approved by the Institutional Ethics Review Committee, AFID (Annex "A"), will involve 62 eligible patients from the Operative Dentistry Department, Armed Forces Institute of Dentistry.
- Trial name
- NCT06975761
- Testing
- Resin Based sealer, ZnO eugenol based sealers
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan