Clinical trials: Symptomatic Irreversible Pulpitis
Pulpitis - Irreversible
Comparison Between Intraligamentary Piroxicam and Articaine
Comparing the efficacy of intra-ligamentary Piroxicam and intra-ligamentary Articaine on pain during and after endodontic treatment of mandibular molars with symptomatic irreversible pulpitis.
- Trial name
- NCT03612323
- Testing
- Intra-ligamentary Piroxicam, Intra-ligamentary Articaine
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
Effectiveness of Premedication on the Success Rate of Inferior Alveolar Nerve Block
Purpose: The aim of this prospective, double-blind, randomized controlled trial is to compare the effect of oral premedication of dexamethasone, ketorolac, meloxicam, ibuprofen or placebo on the success of inferior alveolar nerve…
- Trial name
- NCT05097768
- Testing
- Dexamethasone 0.5mg, Ketorolac 10 Mg Oral Tablet, Meloxicam 7.5 mg
- Where
- Saudi Arabia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Alfarabi Colleges
Symptomatic Irreversible Pulpitis
Occlusal Reduction Effect on Postendodontic Pain
The aim of this study, thus, was to assess the effect of occlusal reduction on postendodontic pain after the first (post-instrumentation) and the second (post-obturation) visit in mandibular posterior teeth with symptomatic…
- Trial name
- NCT04186897
- Testing
- Occlusal reduction
- Volunteers
- 308 people
- Sponsor
- Cairo University
Pulpitis - Irreversible
Effect of Intrapulpal Injections on the Post-endodontic Pain
To achieve painless treatment in patients with a failed primary IANB, supplementary anesthesia has been advised. The majority of the studies evaluating intrapulpal injections have been performed on asymptomatic teeth.
- Trial name
- NCT06088446
- Testing
- Supplementary anesthetic injections
- Where
- India
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Jamia Millia Islamia
Pulpitis - Irreversible
SCN9A Gene Expression and Inflammatory Cytokines
Voltage-gated sodium channels, especially Nav1.7 encoded by the SCN9A gene, are key regulators of nociceptive transmission. Upregulation of SCN9A has been associated with increased neuronal excitability and heightened pain…
- Trial name
- Gene Expressio (NCT07532200)
- Testing
- Inferior Alveolar Nerve Block
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jamia Millia Islamia
Symptomatic Irreversible Pulpitis (SIP)
Short Term Comparative Assessment of MTA and Biodentine in Complete Pulpotomy for Symptomatic Irreversible Pulpitis
All Patients coming to the Operative Dentistry Department (DIDC-DUHS) with complain of pain in posterior teeth will be invited to participate. The treatment will be done by one dentist.
- Trial name
- NCT07483788
- Testing
- Biodentine pulpotomy
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Irreversible Pulpitis (Toothache)
Comparative Evaluation of Intraligamentary Injection of Dexamethasone, Diclofenac Sodium, and Chymotrypsin for Enhancing the Success of 4% Articaine Buccal Infiltration in Mandibular Molars With Symptomatic Irreversible Pulpitis
The goal of this clinical trial is to compare anesthetic success rates of intraligamentary dexamethasone, diclofenac sodium, and chymotrypsin administered prior to buccal 4% articaine infiltration in mandibular molars with…
- Trial name
- NCT07506265
- Testing
- Dexamathsone 4mg/ml associated with experimental arm, Diclofenac Sodium (DCS), chymotrypsin
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Fayoum University
Endodontic Disease, Post Operative Pain
Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment
This study will assess the efficacy of two local anesthetics (2% lidocaine 1:100,000 epinephrine and 0.5% bupivicaine 1:200,000 epinephrine) in reducing post-operative pain in patients receiving endodontic treatment.
- Conditions
- Endodontic Disease, Post Operative Pain, Symptomatic Irreversible Pulpitis
- Trial name
- NCT05338671
- Testing
- Local anesthetic
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Washington
Symptomatic Irreversible Pulpitis (SIP)
Impact of Intracanal Cryotherapy and Corticosteroids on Post Endodontic Pain
The aim of the study: is to evaluate efficiency of using either intracanal corticosteroids or intracanal cryotherapy as a final flush irrigation on post endodontic pain in lower molar teeth with symptomatic irreversible pulpitis.
- Trial name
- NCT07676396
- Testing
- dexamethasone, Cold Saline, cold sodium hypochlorite
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- October 6 University
Symptomatic Irreversible Pulpitis (SIP), Symptomatic Irreversible Pulpitis With Apical Peridontitis
Postoperative Pain After Single-Cone Root Canal Obturation Using Three Sealers
The goal of this clinical trial is to compare post-treatment pain after root canal therapy in adults with irreversible pulpitis using different root canal sealers.
- Trial name
- POP-RCT (NCT07434141)
- Testing
- Endoseal TCS, Neosealer, AH Plus
- Where
- Iran
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Symptomatic Irreversible Pulpitis
Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis
The purpose of this study is to evaluate the success of inferior alveolar nerve block, after the local application of Mepivacaine plus Tramadol in patients with symptomatic irreversible pulpitis.
- Trial name
- NCT02110966
- Testing
- Mepivacaine, Mepivacaine plus Tramadol
- Where
- Mexico
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Daniel Chavarría Bolaños
Postoperative Pain
Effect of Pretreatment Dexamethazone on Pain and Success of Nerve Block
A Comparative Evaluation of the effect of pretreatment dexamethasone versus placebo on post-endodontic pain and success of inferior alveolar nerve block in Mandibular molars with symptomatic Irreversible Pulpitis: A Blinded…
- Trial name
- NCT03199482
- Testing
- Dexamethasone Oral Tablet
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpits
Effect of Emergency Pulpotomy Versus Pulp Extirpation on Anesthetic Efficacy in Endodontic Treatment of Acute Pulpitis
Irreversible pulpitis is an inflammatory condition of the dental pulp, highly painful, and one of the main reasons for seeking emergency dental treatment.
- Trial name
- NCT04599244
- Testing
- emergency pulpotomy
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis, Postoperative Pain
Evaluation of Trans-mucosal Bio-adhesive Discs of Diclofenac Potassium on the Anesthetic Success and Postoperative Pain in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial
The aim of the proposed study is to compare the effect of single dose of Diclofenac Potassium premedication as trans-mucosal bio-adhesive discs versus placebo on the effectiveness of the inferior alveolar nerve block and…
- Trial name
- NCT04585438
- Testing
- Diclofenac Potassium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain
Assessment of Post-Operative Pain After Using Cryotherapy and Dexamethasone
Evaluation and comparing the effect of cryotherapy and dexamethasone on inflammatory mediators and post-operative pain in symptomatic irreversible pulpitis with acute apical periodontitis.
- Trial name
- NCT07738302
- Testing
- cold NaOCl , dexamethasone, NaOCl, dexamethasone, cold NaOCl and cold saline
- Volunteers
- 60 people
- Sponsor
- Suez Canal University
Symptomatic Irreversible Pulpitis, Postoperative Pain
Effect of Preoperative Video-Guided Breathing on Pain in Symptomatic Irreversible Pulpitis
The goal of this randomized controlled clinical trial is to evaluate whether a brief preoperative video-guided breathing exercise reduces postoperative pain in adults undergoing single-visit root canal treatment for symptomatic…
- Trial name
- NCT07859267
- Testing
- Video-Guided Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Cukurova University
Symptomatic Irreversible Pulpitis
Postendodontic Pain on Using Max-i-Probe vs NaviTip as Irrigation Needles
The aim of this prospective, randomized, clinical trial was to evaluate the effect of the side-vented Max-i-Probe versus the end-vented NaviTip as endodontic needles during syringe irrigation on post-operative pain in adult…
- Trial name
- NCT04119661
- Testing
- Max-i-Probe, NaviTip
- Volunteers
- 180 people
- Sponsor
- Cairo University
Endodontic Inflammation
Comparison Between the Vibringe and the Conventional Needle
The Vibringe is the first endodontic sonic irrigation system that enables delivery and activation of the irrigation solution in the root canal, in only one step.
- Trial name
- NCT03551587
- Testing
- Vibringe
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis
Diclofenac Potassium on IANB Efficacy in Symptomatic Irreversible Pulpitis
The aim of this clinical trial is to evaluate the effect of pre-operative administration of diclofenac potassium on the efficacy of inferior alveolar nerve block on using 2% mepivacaine anaesthetic agent in patients with…
- Trial name
- NCT03163420
- Testing
- Diclofenac potassium
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Pulpitis
Comparison Between Reciproc and Oneshape Systems
A randomized clinical trial to assess postoperative pain in patients with symptomatic irreversible pulpitis after using Reciproc versus One Shape rotary NiTi Systems.
- Trial name
- NCT02940782
- Testing
- Reciproc single file system, One Shape single file system, X-smart Plus, Dentsply Maillefer, Ballaigues, Switzerland
- Volunteers
- 54 people
- Sponsor
- Cairo University