Clinical trials: Symptom Management
Pneumonia, Childhood Pneumonia
Pneumonia Case Management Practices in Pakistan
Pneumonia in Pakistan continues to be the leading killer of children under five. Although various national and provincial programs have tried to tackle this but they have not been able to achieve the desired outcomes.
- Conditions
- Pneumonia, Childhood Pneumonia, Infectious Disease, Acute Respiratory Infection
- Trial name
- NCT03869099
- Testing
- Pneumonia Case Management Practices
- Where
- Pakistan
- Volunteers
- 160 people
- Sponsor
- University of Edinburgh
Pain, Heart Failure, Congestive
Help Veterans Experience Less Pain Study (HELP-Vets)
Our purpose is to evaluate the reliability and validity of the '5th vital sign' in everyday practice settings and to compare the relationship of pain to other symptoms and pain treatment in patients with cancer, CHF, and patients…
- Conditions
- Pain, Heart Failure, Congestive, Signs and Symptoms
- Trial name
- HELP-Vets (NCT00230932)
- Where
- United States
- Volunteers
- 654 people
- Sponsor
- US Department of Veterans Affairs
Obesity
Efficacy of Tirzepatide for Weight Management in Patients With Suboptimal Weight Loss After Bariatric Surgery: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Many people who have bariatric (weight-loss) surgery do not lose as much weight as expected, or they regain weight over time. This study will test whether a medicine called tirzepatide can help these patients lose more weight and…
- Trial name
- TirBaS (NCT07829198)
- Testing
- Tirzepatide
- Where
- 3 sites in Portugal
- Volunteers
- 70 people
- Sponsor
- Universidade do Porto
COPD
Acoustic and Volumetric Measurements in Order to Objectify Bronchial Congestion in Patients With Obstructive Respiratory Pathologies Within the Framework of Their Management in Respiratory Physiotherapy for Decongestion
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease defined by permanent airway obstruction. In this disease, a large part of the muscular work is taken up by breathing (fight against bronchial, parietal…
- Trial name
- MUKROBS (NCT05480163)
- Testing
- Measurement records
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Association des Réseaux Bronchiolite
Chronic Pain
Feasibility Study of an Online Self-management Program for Chronic Non-cancer Pain
Based on a mixed-methods design, the objective of this trial is to assess the feasibility and acceptability of the "Agir pour moi" program, an 8-week online self-management program for chronic non-cancer pain (CNCP).
- Trial name
- NCT05319652
- Testing
- Pain self-management program
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- CHU de Quebec-Universite Laval
Respiratory Aspiration
Acceptability and Feasibility of a New Postural Management Night-time Intervention to Improve Respiratory Health of Children With Complex Neuro-disability
This research concerns children with complex neuro-disability. Damage to the developing brain leads to lifelong disturbances in motor control, seizures, cognition, communication, eating and drinking, and behaviour.
- Trial name
- Breathe-Easy (NCT06039852)
- Testing
- Novel Postural Management Night-time Intervention
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Sussex Community NHS Foundation Trust
Chest Tube Removal, Children
The Effects of EMLA Cream and Cold Application on Pain, Fear and Vital Signs Before Chest Tube Removal in Children
This study is being conducted to determine the effect of EMLA cream and cold application on pain, fear and vital signs before chest tube removal in children aged 7-18 years.
- Conditions
- Chest Tube Removal, Children, Pain Management
- Trial name
- NCT06913855
- Testing
- EMLA Cream, Cold application
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul Medeniyet University
Metastatic Pancreatic Cancer, Unresectable Pancreatic Cancer
EL CENTRO: Engaging Latinos in the Center of Cancer Treatment Options
The objective of this study is to improve the chemotherapy decision making process for Latinos with advanced gastrointestinal cancers.
- Conditions
- Metastatic Pancreatic Cancer, Unresectable Pancreatic Cancer, Metastatic Colorectal Cancer
- Trial name
- NCT03602885
- Testing
- Usual chemotherapy education (CE), Chemotherapy education intervention (CEI)
- Where
- 5 sites in United States
- Volunteers
- 10 people
- Sponsor
- Dana-Farber Cancer Institute
Congenital Heart Disease
Evaluation of Panel Reactive Antibody in Children Following Stage I Palliation for Hypoplastic Left Heart Syndrome
The purpose of this study is to determine whether children and adolescents 8-18 years of age with HLHS and related lesions who have undergone stage I palliation during infancy using an allograft patch demonstrate continued…
- Trial name
- NCT01135485
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Pennsylvania
Epilepsy, Cognitive Dysfunction, Cognitive Disorder
HOBSCOTCH-YOUTH and Young Adults
The goal of this clinical trial is to learn more about the home-based epilepsy self-management program, HOBSCOTCH, for improving cognitive function (thinking and memory) and quality of life specifically in young adults, ages 18 …
- Conditions
- Epilepsy, Cognitive Dysfunction, Cognitive Disorder, Memory and Thinking Problems
- Trial name
- NCT07735715
- Testing
- HOBSCOTCH/HOBSCOTCH-YOUTH
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Pain and Anxiety, Dislocation
Virtual Reality in the Management of Painful or Anxiety-provoking Procedures in Emergency Departments
Study and evaluate the effectiveness of virtual reality in pain management.
- Conditions
- Pain and Anxiety, Dislocation, Suture
- Trial name
- VR (NCT06425835)
- Testing
- VR device
- Volunteers
- 300 people
- Sponsor
- University of Monastir
Implementation of a Chronic Disease Management Programme, COPD
Effects of an Active Implementation of a Guideline for Chronic Obstructive Pulmonary Disease
Aims: To design a proactive implementation strategy for a chronic-disease-management-programme. To describe effects of the active implementation of a programme for COPD-patients measured on patient-related goals and use of health…
- Trial name
- NCT01228708
- Testing
- Active implementation of a guideline for chronic disease
- Volunteers
- 3,021 people
- Sponsor
- University of Aarhus
Postpartum Hemorrhage
Intrauterine Balloon (Bakri©) Versus Uterine Tamponade With Chitosan Gauze (Celox PPH©) in the Management of Postpartum Hemorrhage Refractory to Medical Treatmen
Postpartum hemorrhage (PPH) remains one of the leading causes of maternal morbidity and mortality worldwide, particularly in low- and middle-income countries.
- Trial name
- NCT06996808
- Testing
- Bakri Baloon, Celox gauze
- Volunteers
- 196 people
- Sponsor
- University of Roma La Sapienza
Constipation
Effect of Abdominal Massage Training Provided to Caregivers on Constipation Management
Constipation is a common and uncomfortable problem among patients receiving palliative care. Alongside usual treatment and nursing care, abdominal massage may help manage constipation.
- Trial name
- NCT07886125
- Testing
- Caregiver Training in Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- HAMİYET KIZIL
Avascular Necrosis, Osteonecrosis
The Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral Head
The purpose of this study is to assess the clinical and x-ray results of patients who are treated with core decompression of the hip and the injection of a bone marrow concentrate and the use of the Bone Graft Substitute Genex®.
- Trial name
- Genex (NCT05706909)
- Testing
- Genex with ABMC
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Advanced Cancer
Cancer End Of Life Evaluation
The aim of this study is to culturally adapt and to validate Quality Of Life tools dedicated to the end of life for French cancer patients.
- Trial name
- CEOLE (NCT01545921)
- Testing
- Quality Of Life questionnaires completion
- Where
- 10 sites in France
- Volunteers
- 179 people
- Sponsor
- Institut Cancerologie de l'Ouest
Arthritis, Rheumatoid Arthritis
A Novel Mobile App & Population Management System to Manage Rheumatoid Arthritis Flares
The overall objective of this proposal is to implement a smart phone application (app) + population management system to monitor rheumatoid arthritis (RA) disease activity between scheduled physician office visits.
- Trial name
- NCT02822521
- Testing
- Mobile Application, Population Management System
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Brigham and Women's Hospital
Multiple Sclerosis, Fatigue
Pilot Study for the Evaluation of the More Stamina in Persons With Multiple Sclerosis
The overall study aims are to explore the feasibility, acceptability, and usability of More Stamina, a mobile app for fatigue self-management for persons with MS.
- Conditions
- Multiple Sclerosis, Fatigue, Chronic Conditions, Multiple
- Trial name
- NCT04244214
- Testing
- More Stamina
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Hospital Italiano de Buenos Aires
Breast Cancer, Fever
Same Day Dosing of Pegfilgrastim in Breast Cancer Patients Undergoing Chemotherapy (TAC)
The purpose of this study is to provide data on the safety and efficacy of pegfilgrastim when administered on the same day versus the next day of chemotherapy, as measured by the duration of grade 4 neutropenia.
- Conditions
- Breast Cancer, Fever, Neutropenia
- Trial name
- NCT00115414
- Testing
- pegfilgrastim, docetaxel, doxorubicin
- Sponsor
- Amgen
Anxiety, Depression
Developing Resilience and Anxiety Management Through the Arts
The Developing Resilience and Anxiety Management Through the Arts (DRAMA) Study examines the degree to which the arts can help to address stress, anxiety, and sad mood in children and adolescents.
- Conditions
- Anxiety, Depression, Mood
- Trial name
- DRAMA (NCT07033052)
- Testing
- Improvisation + Wellness, Improvisation, Social Craft
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Case Western Reserve University