Clinical trials: Swallowing
Eating Disorders
Determining the Response to Sipping Beverages Without Swallowing in People With Eating Disorders
This study will use a sipping and spitting exercise to better understand the brain's response to food intake in people with eating disorders.
- Trial name
- NCT00353548
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Gastroesophageal Reflux Disease, Globus Pharyngeus
Manual Therapy Effects on Upper and Lower Esophageal Sphincter Pressures
The aim of this study is to test the influence of manual cervical traction and chest stabilization maneuvers on pressures in upper and lower esophageal sphincters.
- Trial name
- NCT03871426
- Testing
- manual therapy
- Where
- Czechia
- Volunteers
- 54 people
- Sponsor
- University Hospital, Motol
Preterm Birth, Tube Feeding
Maternal Role in Oral Feed Establishment in Preterm Neonates
Hypothesis Preterm babies who receive sensory motor stimulation from their mothers as compared to trained nurses will 1. Start taking oral feed at the same time as compared to control group 2.
- Conditions
- Preterm Birth, Tube Feeding, Swallowing Disorder, Maternal Care Patterns
- Trial name
- NCT05484726
- Testing
- perioral sensory motor stimulation
- Where
- Pakistan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Fatima Memorial Hospital
Reflux, Gastroesophageal, Achalasia
The Effect of Physiotherapy on Post POEM Reflux
Per-oral endoscopic myotomy has been used as a treatment method of esophageal achalasia. Patients who undergo POEM as a treatment of achalasia are often presented with development of reflux as a side effect of the surgery.
- Conditions
- Reflux, Gastroesophageal, Achalasia, Esophagitis
- Trial name
- NCT05326113
- Testing
- Physiotherapy, Control group
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Deglutition Disorder
Effect of Pre-emptive Transcutaneous Neuro-muscular Electrical Stimulation for Dysphagia in Long Term Intubated Patients
It was well known that long term intubation caused a various kind of abnormal presentations of dysphagia such as the increased aspiration risk, the decreased gag reflex, mucosal pathology, the airway stenosis and so on.
- Trial name
- NCT01202968
- Testing
- Transcutaneous neuro-muscular electrical stimulation
- Where
- South Korea
- Sponsor
- Ulsan University Hospital
Dysphagia, Endotracheal Intubation
Effects of an Swallowing and Oral Care Program in Patients Following Prolonged Endotracheal Intubation
This pre-and post-intervention study enrolled adult Intensive Care Unit(ICU) patients (≥50 years) successfully extubated after ≥48 hours endotracheal intubation and without preexisting neuromuscular disease or swallowing…
- Conditions
- Dysphagia, Endotracheal Intubation, Intake Status, Swallowing Status
- Trial name
- NCT02334774
- Testing
- Swallowing and Oral Care Program
- Where
- Taiwan
- Volunteers
- 63 people
- Sponsor
- National Taiwan University Hospital
Muscle Loss
Branched Chained Amino Acid Supplement in Patients Undergoing Lower Limb Bone Cancer Curettage for Bone Metastasis
Postoperative muscle loss is common in patients with bone metastases undergoing lower limb bone cancer curettage, affecting both limb skeletal muscles and potentially swallowing-related muscles.
- Trial name
- NCT06604910
- Testing
- branched chained amino acid
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Dysphagia, Swallowing Disorder
tACS and tRNS Studies on Brain Control of Swallowing
Transcranial alternating current stimulation (tACS) and transcranial random noise stimulation (tRNS) are two (CE marked medical devices) new, non-invasive (over the scalp) brain stimulation (NIBS) techniques.
- Trial name
- NCT04040803
- Testing
- Transcranial alternating current stimulation (tACS) and transcranial random noise stimulation (tRNS)
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Dysphagia
Study: C-Collar and Dysphagia
The purpose of this study is to characterize oral-pharyngeal swallow function with the guidance of videofluoroscopy under two conditions, with and without cervical bracing, in patients determined to have dysphagia.
- Trial name
- NCT03349125
- Testing
- Collar On, Collar Off
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Wisconsin, Madison
Gastroesophageal Reflux Disease
Stellate Ganglion Block on Gastroesophageal Reflux Disease
The goal of this clinical trial is to explore Clinical Effect of Stellate Ganglion Block on Gastroesophageal Reflux Disease. The main question it aims to answer is: Can stellate ganglion block improve gastroesophageal reflux…
- Trial name
- NCT06319521
- Testing
- Rehabilitation therapy, Stellate ganglion block, Lidocaine hydrochloride
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
Swallowing, Dysphagia
Cerebellar Metaplasticity in the Swallowing Motor System
Dysphagia is common and leads to significant morbidity and mortality within healthcare settings. Current approaches to dysphagia management involve altering the consistency of food and fluids.
- Trial name
- NCT06721533
- Testing
- Cerebellar rTMS
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Body Weight, Post-Op Complication
Development of Machine Learning Models for the Prediction of BMI and Complications After Bariatric Surgery (CABS-Study)
This Study aims to develop machine learning models with the ability to predict patients' BMI and complications after Bariatric Surgery (CABS-Score).
- Conditions
- Body Weight, Post-Op Complication, Anastomosis, Leaking, Hiatal Hernia
- Trial name
- NCT05710913
- Where
- Switzerland
- Volunteers
- 10,000 people
- Sponsor
- Dr. Med Anas Taha
Esophageal Motility Disorders, Gastric Motor Dysfunction
Gastrointestinal Dysmotility on Aspiration Risk
The hypothesis of this study is that esophageal and gastric dysmotility increase the risk of developing aspiration-associated symptoms in children with neurologic impairment.
- Conditions
- Esophageal Motility Disorders, Gastric Motor Dysfunction, Aspiration Pneumonia, Gastro Esophageal Reflux
- Trial name
- NCT05455359
- Testing
- Prucalopride, Famotidine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Boston Children's Hospital
Dysphagia, Neuromuscular Diseases
Validation of the French Version of the Sydney Swallow Questionnaire in Patients With Neuromuscular Diseases
Measurements of dysphagia severity are important when making management decisions and in the objective evaluation of swallowing impairments.
- Trial name
- NCT02845362
- Testing
- Sydney Swallow Questionnaire
- Where
- 2 sites in Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Laryngopharyngeal Reflux, Zenker's Diverticulum
Laryngopharyngeal Reflux Before and After Cricopharyngeal Myotomy
The purpose of this study is to see if people with reflux with a Zenker's diverticulum have increased reflux into the throat following a cricopharyngeal myotomy.
- Trial name
- NCT01880892
- Testing
- Cricopharyngeal myotomy, PH probe Testing
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Gastroesophageal Reflux Disease
An Explorative Trial to Evaluate the Pharmacodynamic Effect of SPD557 on Reflux Parameters in Refractory GERD Patients
The purpose of this trial is to investigate the pharmacodynamic effect on reflux parameters of SPD557 tablets (0.5 mg t.i.d., on top of PPI treatment) in patients with Gastroesophageal Reflux Disease (GERD) with persistent…
- Trial name
- NCT01370863
- Testing
- SPD557
- Where
- 15 sites in Belgium, France and 4 more
- Volunteers
- 67 people
- Sponsor
- Shire
Esophagus Disorder, Esophageal Achalasia
Impact of Antibiotic Prophylaxis in Per-oral Endoscopic Myotomy for Esophageal Motor Disorders
No recommendation regarding antibiotic prophylaxis and preparation modalities are available for patients with esophageal motor disorders who benefit from Per-Oral Endoscopic Myotomy (POEM).
- Trial name
- NCT03944863
- Testing
- Antibiotics
- Volunteers
- 252 people
- Sponsor
- Société Française d'Endoscopie Digestive
GERD
Pre- and Post-Therapy Evaluation of Air-Associated Symptoms in Patients With Gastro-esophageal Reflux Disease (GERD): Assessing the Role of Speech and Language Therapy
Patients with gastroesophageal reflux disease (GERD) may present with concomitant gas-related symptom (GRS) such as supragastric or gastric belching, and aerophagia.
- Trial name
- LAS (NCT07634614)
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Prof Urs Zingg
Dysphagia
Measuring Pharyngeal Muscle Improvements Following Behavioral Swallowing Exercises
The purpose of this study is to learn more about how exercise and protein supply affect swallow muscles. Twenty healthy older adults will be recruited from local community centers, physician offices, and retirement communities…
- Trial name
- NCT05080725
- Testing
- TelePEPP intervention
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Gastro-esophageal Reflux
Safety & Initial Efficacy of the LunGuard PFT Sys. on Enteral-Fed, Sedated and Mechanically Ventilated Patients Peristaltic Feeding Tube
This study is designated to test the safety and initial efficacy of the LunGuard's PFT device for reduction of GER. Enterally-Fed, Sedated and Mechanically Ventilated Critically Ill Patients in the ICU will have the PFT…
- Trial name
- PFT (NCT02609620)
- Testing
- Peristaltic Feeding Tube, ConvaTec Levin Duodenal Tube
- Volunteers
- 20 people
- Sponsor
- LunGuard Ltd.