Clinical trials: Suture
Rectocele
Barbed Suture Versus Non-Barbed Suture for Posterior Colporrhaphy
The aim of this randomized clinical trial is to compare barbed suture versus non-barbed suture at the time of posterior repair on postoperative pain scores as measured by a visual analog scale (VAS) at 6 weeks.
- Trial name
- NCT04658784
- Testing
- 2-0 dioxanone, glycolide and trimethylene carbonate, 2-0 polydioxanone
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Wake Forest University Health Sciences
Cerebrospinal Fluid Leak
The EVICEL® Neurosurgery Phase III Study
The objective of this study is to evaluate the safety and efficacy of EVICEL® Fibrin Sealant (Human) for use as an adjunct to sutured dural repair in cranial surgery.
- Trial name
- NCT02457546
- Testing
- EVICEL Fibrin Sealant, Hydrogel sealant
- Where
- 26 sites in United States, Australia and 4 more
- Volunteers
- 234 people
- Sponsor
- Ethicon, Inc.
Bicep Tendinitis, Biceps; Tenosynovitis
A Prospective Study Comparing Suture Anchor and Soft Tissue Pectoralis Major Tendon Techniques for Biceps Tenodesis
This is a prospective randomized controlled trial comparing two common techniques of long head of biceps tendon tenodesis in shoulder surgery. Numerous techniques of biceps tenodesis currently exist and are commonly performed.
- Conditions
- Bicep Tendinitis, Biceps; Tenosynovitis, Biceps Tendon Disorder
- Trial name
- NCT03529162
- Testing
- Long head of Biceps Tenodesis
- Where
- 3 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Hysterotomy
Barbed Suture for Hysterotomy Closure During Cesarean Section
This is a randomized controlled trial. The purpose of this study is to see if patients whose uterine incision (hysterotomy), at the time of scheduled cesarean section, is closed with barbed suture, have less blood loss compared…
- Trial name
- NCT04622267
- Testing
- Barbed suture, Standard antimicrobial suture
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Nasal Obstruction
Comparison of a Septal Stapler to Suture Closure in Nasal Septoplasty
The primary objective of this study is to determine if there is a time savings in the operating room by using a septal stapler instead of suture in closure of primary septoplasty.
- Trial name
- NCT01541839
- Testing
- Septal Stapler
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Alberta
Wound Closure Technique
A Comparison of Polyglactin 910 and Chromic Gut Suture in the Closure of Punch Biopsy Sites
Some Dermatologists prefer absorbable suture to non-absorbable suture in the closure of punch biopsy sites. The reason these are often preferred is because patients do not have to pay for another visit to get the suture material…
- Trial name
- NCT01722994
- Testing
- Polyglactin 910 sterile synthetic absorbable suture (Ethicon), Chromic Gut Sterile absorbable Suture (Ethicon)
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- University of Mississippi Medical Center
Wound; Knee
The Use of STRATAFIX Suture Device Compared to Standard-of-care for Deep Tissue Closure in Total Knee Arthroplasty
The STRATAFIX (Ethicon, Johnson and Johnson, Somerville, New Jersey) Knotless Tissue Control suture device is a barbed suture that uses anchor technology to securely engage with the soft tissues while also eliminating the need…
- Trial name
- NCT03285529
- Testing
- STRATIFIX, VICRYL
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Cleveland Clinic
Wound Heal
Prospective Randomized Trial of Dermabond Prineo in Total Knee Arthroplasty
In this prospective pilot study examining the superficial closure during total knee arthroplasty, active subjects will receive the STRATAFIX Spiral Knotless Tissue Control Device for subcuticular closure in addition to DERMABOND…
- Trial name
- NCT03285542
- Testing
- DERMABOND, Staples
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Cleveland Clinic
Hallux Valgus Repairs, Medial or Lateral Instability Repairs/Reconstructions
A Study of the Safety and Performance of the MINITAC◊ Titanium 2.0 Suture Anchor
This is a retrospective study evaluating the safety and performance of the MINITAC Suture anchors for extremities repair. Data will be used to support Notified Body (BSI) requirements for extremities repair indications.
- Conditions
- Hallux Valgus Repairs, Medial or Lateral Instability Repairs/Reconstructions, Achilles Tendon Repairs/Reconstructions, Midfoot Reconstructions
- Trial name
- MINITAC (NCT04186481)
- Testing
- MINITAC Ti 2.0 suture anchor
- Where
- Australia
- Volunteers
- 32 people
- Sponsor
- Smith & Nephew, Inc.
Rotator Cuff
Safety of Treatment of Shoulder Repair
This study evaluates the safety of the HEALICOIL Knotless Suture Anchors in patients requiring a repair of the rotator cuff tendon repair
- Trial name
- HEALICOIL_KNTL (NCT04552119)
- Testing
- HEALICOIL Knotless PEEK, HEALICOIL Knotless REGENESORB
- Where
- 5 sites in United States
- Volunteers
- 138 people
- Sponsor
- Smith & Nephew, Inc.
Surgical Site Infection, Surgical Wound Infection
Antibacterial-coated Sutures at Time of Cesarean
Abdominal closure with antibacterial-coated sutures has been shown to reduce wound infections after a number of surgical procedures, but none of the previous trials included cesarean delivery.
- Conditions
- Surgical Site Infection, Surgical Wound Infection, Cesarean Section; Infection, Cesarean Section Complications
- Trial name
- ASTC (NCT03386240)
- Testing
- Vicryl-plus, monocryl-plus, PDS-plus (Triclosan-coated Sutures), Vicryl, monocryl, PDS (not coated with triclosan)
- Where
- United States
- Volunteers
- 1,169 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Closure of Vaginal Cuff at Laparoscopic Hysterectomy
Barbed Suture vs Smooth Suture for Vaginal Cuff Closure
This study compares outcomes among patients having a total laparoscopic hysterectomy. This involves removing the uterus and cervix using a laparoscopic or keyhole technique.
- Trial name
- NCT01262573
- Testing
- Closure of vaginal cuff
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Brigham and Women's Hospital
Polyps
Evaluation of an Endoscopic Suturing System for Tissue Apposition in Colonic Polypectomy
The purpose of this study is to show that the surgical site in the bowel wall can be sewn closed in the colon or intestine, with a new sewing device after removal of a benign polyp according to standard of care.
- Trial name
- NCT00553436
- Testing
- Tissue Apposition System (TAS) Device
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Ethicon Endo-Surgery
Pregnancy, Cesarean Section
Comparison of Staples Versus Prolene Suture for Skin Closure at Cesarean Delivery
Currently different materials are used to close the skin after a cesarean delivery, including absorbable suture, non-absorbable suture and staples.
- Trial name
- NCT01509950
- Testing
- Staples, Prolene non-absorbable sutures, Absorbable Sutures
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stanford University
Pelvic Organ Prolapse
Uterosacral Ligament Suspension Clip
This study seeks to gain a more thorough understanding of the postoperative location of the sutures placed during uterosacral ligament suspension.
- Trial name
- USLS (NCT02700997)
- Testing
- Vascular Clip
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- TriHealth Inc.
Regional Anesthesia, Sciatic Nerve Block
Comparing Through-the-Needle With Suture-Method Catheter Designs for Popliteal Nerve Blocks
Following painful surgical procedures, postoperative analgesia is often provided with a single-injection peripheral nerve block.
- Trial name
- NCT03442036
- Testing
- Suture-Method Technique, Through-the-Needle Technique
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Port-A-Cath Placement, Octylcyanoacrylate
Comparison of Topical Skin Adhesive to Subcuticular Suture Closure of Implantable Port Incisions
Hypothesis is that incision closure with octylcyanoacrylate is inferior to closure with stitches in Port a Cath patients, who, as a population, are at increased risk for complications.
- Trial name
- NCT02212977
- Testing
- Octylcyanoacrylate, Suture
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Duke University
Wound, Cardiac Arrhythmia
ZIPS Study - Zip Incision aPproximation vs. Suture
ZipLine Medical, Inc. has developed a novel, non-invasive skin closure device called "Zip Surgical Skin Closure" to replace sutures, staples and glue for closure of the skin layer for surgical incisions or laceration repair.
- Trial name
- ZIPS (NCT02213510)
- Testing
- Zip Surgical Skin Closure Device, Standard Suture Closure
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Diego
Wound Infection, Wound Complication
Randomized Clinical Trial of Skin Closure With Staples Versus Suture
Women with gynecologic cancers are often obese and have other risk factors for post-operative wound separation. Data from obstetrics and orthopedic surgery literature have shown a decreased risk of wound separation and…
- Trial name
- NCT01977612
- Testing
- 4-0 monofilament suture, Stainless steel staples
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- Washington University School of Medicine
Laceration
Trial Comparing Cosmetic Outcomes of Pediatric Laceration Closure Using Skin Glue, Medical Tape Versus Stitches
There are several methods of closing a skin cut: stitches, skin glue, and medical tape. Stitches have been used for a long time to close skin cuts.
- Trial name
- NCT03280628
- Testing
- Absorbable Sutures, Steri-Strips, Dermabond
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Vanderbilt University Medical Center