Clinical trials: Surgical Site Infection (SSI)
Prosthetic-joint Infection, Dysbiosis
Probiotics in the Prevention of Recurrent Prosthetic Joint Infection of the Hip and Knee
Prosthetic joint infection (PJI) is one of the most devastating complications following total joint arthroplasty (TJA) of the hip and knee. Standard of care (SOC) treatment includes surgery and antimicrobials.
- Trial name
- NCT06636669
- Testing
- Probiotic, Standard of care
- Where
- 2 sites in United States
- Volunteers
- 152 people
- Sponsor
- Boston Medical Center
Cesarian Scar, Surgical Site Infection (SSI)
Polyurethane Foam Versus Gauze Dressing After Cesarean Delivery in a Standardized Surgical Setting: A Prospective Randomized Controlled Trial
Background: Cesarean delivery is one of the most frequently performed surgical procedures worldwide, and postoperative scar quality remains an important patient-centered outcome.
- Trial name
- CSWD_RCT (NCT07482202)
- Testing
- Polyurethane Foam dressing(Mepilex Border Flex), Conventional Gauze Dressing
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yewon Jung
Emergency Surgery, Surgical Site Infections
Irrisept in Emergency General Surgery Patients
This is a single institution, randomized study conducted to determine if irrigation with Irrisept in emergency general surgery patients results in lower surgical site infections compared to normal saline irrigation.
- Trial name
- NCT07048899
- Testing
- Chlorhexidine, Normal Saline
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- The University of Texas Health Science Center at Tyler
Surgical Site Infection, Post-Op Infection
Analysis of Risk Factors for Surgical Site Infections in Patients With Acute Abdomen at Hospital of State University of Haiti
The purpose of this study is to identify the risk factors associated with surgical site infection.
- Trial name
- NCT06480344
- Where
- Haiti
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Haiti
Next Generation Sequencing (NGS), Surgical Site Infection (SSI)
Efficacy of Integrating Next Generation Sequencing for Treatment of Surgical Site Infection After Fracture Fixation:
The study focuses on the serious problem of infections and wound-healing issues that can happen after high-energy bone fractures.
- Conditions
- Next Generation Sequencing (NGS), Surgical Site Infection (SSI), Fracture Fixation
- Trial name
- NGS (NCT07458230)
- Testing
- NGS diagnostic findings
- Where
- 18 sites in United States
- Volunteers
- 250 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Surgical Site Infection
SSI Rates in Patients Undergoing Mastectomy Without Reconstruction- A Multicenter, Double-blinded RCT.
Breast cancer is the second most prevalent malignancy in the world and an important component of treatment warrants surgical procedures such as mastectomy.
- Trial name
- NCT04577846
- Testing
- Cephalexin 500 MG
- Where
- 3 sites in Pakistan
- Volunteers
- 384 people
- Sponsor
- Aga Khan University
Surgical Site Infection (SSI)
Skin Adhesive Plus Intra-cuticular Suture Versus Suture Alone for Cesarean Skin Closure
The goal of this randomized control trial is to compare two skin closure techniques after cesarean section. Both techniques are currently in wide use but no comparison between the two was reasserted yet.
- Trial name
- NCT07483411
- Testing
- Dermabond
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Doron Kabiri
Surgical Site Infection (SSI), Wound Healing Complication
Subcutaneous Suture Versus no Subcutaneous Suture for Abdominal Wound Closure
Surgical site infections are among the most frequent complications after abdominal surgery and are associated with impaired wound healing, prolonged hospital stay, additional treatments, and increased healthcare costs.
- Trial name
- SUTURE (NCT07615517)
- Testing
- subcutaneous suture
- Where
- Germany
- Volunteers
- 655 people, healthy volunteers welcome
- Sponsor
- University Hospital Augsburg
Surgical Site Infection, Length of Stay
Prevena to Prevent Surgical Site Infection After Emergency Abdominal Laparotomy
Post-operative wound complications in abdominal surgery have a major impact on patient outcomes and the real impact of Closed incision negative pressure therapy (CINVt) is not clear in the literature moreover concerning its…
- Conditions
- Surgical Site Infection, Length of Stay, Seroma, Hematoma
- Trial name
- CiPNT/SSI (NCT04496180)
- Testing
- Closed incision negative pressure therapy versus standard dressing after emergency abdominal laparotomies
- Volunteers
- 334 people
- Sponsor
- University Hospital, Geneva
Acute Appendicitis, Superficial SSI
Laparoscopic vs Open Appendectomy
his randomized controlled trial was conducted to compare the frequency of superficial surgical site infections (SSIs) following laparoscopic appendectomy and open appendectomy in patients undergoing surgical treatment for acute…
- Trial name
- NCT07841444
- Testing
- Laparoscopic appendectomy, Open Appendectomy
- Where
- Pakistan
- Volunteers
- 276 people
- Sponsor
- Quaid-e-Azam Medical College
Surgical Site Infection
Cheetah - Sterile Glove and Clean Instrument Change at the Time of Wound Closure to Reduce Surgical Site Infection
To assess whether the practice of using separate sterile gloves and instruments to close wounds at the end of surgery compared to current routine hospital practice can reduce surgical site infection
- Trial name
- Cheetah (NCT03980652)
- Testing
- Change of gloves and sterile instruments
- Volunteers
- 12,800 people
- Sponsor
- University of Birmingham
Surgical Site Infection (SSI), Cesarean Section Wound
Subcutaneous Drain Versus Wound Irrigation by Normal Saline for Prevention of Surgical Site Infection Following Caesarean Section in Obese Patients.
This is a prospective randomized controlled trial conducted at Ain Shams University Maternity Hospital to compare subcutaneous drain versus wound irrigation with normal saline for the prevention of surgical site infection…
- Trial name
- NCT07517718
- Testing
- Subcutaneous Drain, Normal Saline
- Where
- Egypt
- Volunteers
- 189 people
- Sponsor
- Ain Shams University