Clinical trials: Surgical Scar
Intervertebral Disc Disorder, Thoracic Intervertebral Disc Disorders
Spine Surgery for Adhesions in Patients Evaluated for Efficacy and Safety of MedicurtainⓇ (Pivotal Study)
This study was designed to evaluate the efficacy and safety of Medicurtain®, an antiadhesion barrier in patients who underwent In Situ Decompression for single level and unilateral herniated lumbar intervertebral disc.
- Conditions
- Intervertebral Disc Disorder, Thoracic Intervertebral Disc Disorders, Thoracolumbar Intervertebral Disc Disorders, Lumbosacral Intervertebral Disc Disorders
- Trial name
- NCT04688281
- Testing
- Medicurtain®, GUARDIX-SG®
- Where
- South Korea
- Volunteers
- 87 people
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Adhesion
PMCF Study for ADEPT® in LaparoscopicGynecologic Surgery
Postoperative adhesions develop in most patients after gynecologic surgery, likely resulting in significant morbidity, complications, and considerable increases in healthcare costs.
- Trial name
- NCT05811585
- Testing
- ADEPT
- Where
- 2 sites in United States, Germany
- Volunteers
- 153 people
- Sponsor
- Baxter Healthcare Corporation
Scar Prevention
Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars From Prior Breast Surgery
This study will compare how well EXC 001 works to improve the appearance of scars in subjects undergoing breast scar revision surgery. The study will also evaluate the safety of EXC 001 in healthy adult subjects.
- Trial name
- NCT01037413
- Testing
- EXC 001
- Where
- 5 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pfizer
Wound of Skin, Abdominal Wound
Safety and Efficacy of MRG-001 in Wound Healing in Abdominoplasty Patients
Surgical excisions are one of the most frequent cutaneous wounds. This study will compare the safety and preliminary efficacy of a novel fixed-dose combination drug MRG-001 in pre-abdominoplasty surgical excisions and scar…
- Trial name
- NCT05844527
- Testing
- MRG-001, Saline
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- MedRegen LLC
Tissue Adhesions, Surgery-Induced
Post Approval Study to Evaluate the Safety and Performance of GENTA-FOIL Resorb® in Hand Surgery
Single arm study to evaluate the safety and performance of Genta-Foil resorb® for the prevention of tissue adhesions
- Trial name
- NCT04482140
- Testing
- Genta-Foil resorb®
- Where
- 3 sites in Greece, United Kingdom
- Volunteers
- 15 people
- Sponsor
- Advanced Medical Solutions Ltd.
Cosmetic Surgery
Effectiveness Study of MIST Therapy After Cosmetic Surgery Procedures of the Face and Body
A clinical trial to evaluate the effect of MIST Therapy on outcomes after cosmetic procedures(including facelifts, blepharoplasties, breast augmentations and reductions, mastopexies, and abdominoplasties) traditionally associated…
- Trial name
- NCT01206855
- Testing
- MIST Therapy, Standard Postoperative Incision Care
- Where
- United States
- Volunteers
- 3,440 people
- Sponsor
- Celleration, Inc.
Post-surgical Scars
CICATRIX in the Treatment of Recent Post-surgical Scars
The purpose of the study is to assess the efficacy of CICATRIX (Asian Gotu Kola or Pennywort) usage in the treatment of recent post-surgical scars.
- Trial name
- NCT00991367
- Testing
- Cicatrix
- Where
- Cuba
- Volunteers
- 90 people
- Sponsor
- Catalysis SL
Surgical Adhesions
Study of PXL01 Versus Placebo to Inhibit Adhesion Formation After Flexor Tendon Surgery
The objectives of the study are to assess efficacy, safety, and handling of PXL01 in patients with flexor tendon injury in zone I or II.
- Trial name
- PHSU02 (NCT01022242)
- Testing
- PXL01
- Where
- 15 sites in Denmark, Germany and 1 more
- Volunteers
- 138 people
- Sponsor
- Pergamum AB
Cicatrix
Juvista in Scar Revision Surgery of Disfiguring Scars
This trial is to determine whether Juvista can prevent scar formation or improve the appearance of scars following scar revision surgery. The trial will involve comparing Juvista to placebo.
- Trial name
- Revise (NCT00742443)
- Testing
- Juvista (avotermin)
- Where
- 47 sites in United States, Denmark and 8 more
- Volunteers
- 350 people
- Sponsor
- Renovo
Scars
Juvista in the Non-surgical Improvement of Existing Scars
Renovo, a Biopharmaceutical company involved in the development of drugs to improve the appearance of scars and enhance wound healing, are proposing to carry out research in improving the appearance of existing scars that are 2-6…
- Trial name
- NCT00821457
- Testing
- Juvista
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Renovo
Post Dermatological Surgery Scars
Effectiveness and Safety Study of Overnight Intensive Patch in Scars
To investigate the effectiveness of an Overnight Intensive Patch (OIP) on improvement of post dermatological surgery scars and its safety over 12 to 24 weeks.
- Trial name
- NCT01910896
- Testing
- Overnight Intensive Patch
- Where
- 9 sites in Germany
- Volunteers
- 125 people
- Sponsor
- Merz Pharmaceuticals GmbH
Scarring
Amniotic Membrane in Decompressive Craniectomy to Reduce Scarring
The purpose of this study is to evaluate the effectiveness of dHACM in reducing scar tissue formation in craniectomy patients as well as facilitating reoperation and repair.
- Trial name
- NCT02033824
- Testing
- dHACM, Craniectomy
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- MiMedx Group, Inc.
Glaucoma, Trabeculectomy
Ologen (OculusGen)-Glaucoma MMC Control in Pakistan
The purpose of this study is to compare the safety and effectiveness of the ologen (OculusGen) Biodegradable Collagen Matrix Implant and the MMC group in filtration surgery.
- Trial name
- NCT00472810
- Testing
- ologen collagen matrix in glaucoma filtering surgery, MMC in glaucoma filtering surgery
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Pro Top & Mediking Company Limited
Hypertrophic Scar
Study to Evaluate Efficacy of OLX10010 in Reducing Recurrence of Hypertrophic Scarring After Scar Revision Surgery
Phase 2a, prospective, randomized, double-blind, intra-subject, placebo-controlled, proof of concept study. Approximately twenty subjects will be randomized 1:1 to one of two treatment arms: Arm A: 2.0 mg/cm OLX10010 biweekly…
- Trial name
- NCT04877756
- Testing
- OLX10010
- Where
- 6 sites in United States
- Volunteers
- 22 people
- Sponsor
- Olix Pharmaceuticals, Inc.
Mammaplasty, Cicatrix
Juvista (Avotermin) in Breast Reduction Surgery Scars
Severe scarring is a common problem following breast reduction surgery, studies have shown that over 64% of patients develop a hypertrophic scar at three months after the operation.
- Trial name
- NCT00432328
- Testing
- Avotermin
- Where
- 6 sites in United Kingdom
- Volunteers
- 39 people
- Sponsor
- Renovo
Keloid
A Study to Evaluate the Effectiveness and Safety of RXI-109 on the Outcome of Keloid Excision Surgery in Healthy Adults
To evaluate the effectiveness of RXI-109 in reducing the recurrence of keloid formation following elective keloid excision.
- Trial name
- NCT02079168
- Testing
- RXI-109
- Where
- 3 sites in United States, Dominican Republic
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- RXi Pharmaceuticals, Corp.
Mohs Surgery
Study of EB-001 in Facial Scar Reduction
This study will evaluate the safety and efficacy of EB-001 in improving wound healing and reducing scar formation in patients undergoing Mohs surgery for skin lesions in the forehead area following a single treatment of EB-001…
- Trial name
- NCT03346902
- Testing
- EB-001, 0.9% Sodium Chloride Injection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Bonti, Inc.
Adhesions, Colectomy
SurgiWrapTM to Reduce Soft Tissue Attachment & Incidence Early Post-Operative Bowel Obstruction in Colorectal Surgery
The purpose of this study is to determine if the use of SurgiWrapTM: (1) prevents/lowers the incidence of Grade 2 or higher soft tissue attachments under the incision made during abdominal surgery, (2) reduces post-operative…
- Trial name
- NCT00531739
- Testing
- Polylactic Acid Sheet
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cytori Therapeutics
Tissue Adhesions
A Randomized Multi-centre Study to Assess the Safety and Manageability of a Laparoscopic Adhesion Barrier in Women Undergoing Gynecologic Laparoscopic Surgery Followed by Second Look Laparoscopy
The purpose of this study is to obtain data on the safety and manageability of applying LABS™ to the uterus and other areas of surgical trauma in the pelvis and abdomen following laparoscopic gynaecologic surgery.
- Trial name
- LABS-1 (NCT02260115)
- Testing
- LABS™, Surgical Control
- Where
- 4 sites in Germany, Greece
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Actamax Surgical Materials LLC
Surgical Scars
Evaluation of the Scar Healing Effects of ChitoCare Medical Scar Healing Gel in Women Undergoing Breast Reduction or Mastopexy Surgery (CHITOSCAR)
Patients undergoing breast reduction or mastopexy surgery will be screened and recruited for participation in the study. Eligible patients will act as their own control with one breast receiving the active intervention…
- Trial name
- CHITOSCAR (NCT06992960)
- Testing
- ChitoCare® medical Scar Healing Gel (Örsáragel), Amoena CuraScar Mammilla Circles Silicone Scar Patch and Amoena CuraScar Anchors Silicone Scar Patch
- Where
- Iceland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Primex ehf