Clinical trials: Surgical Procedures, Operative
Infection of Total Knee Joint Prosthesis, Aseptic Loosening of Prosthetic Joint
Surgical / Economic Effect of the Aquamantys System in Blood Management for Aseptic and Septic Revision TKA
To assess the surgical and economic effectiveness of the Aquamantys System in managing intra- and post-operative blood loss, and reducing transfusion needs in patients undergoing both aseptic and septic revision total knee…
- Trial name
- NCT02266407
- Testing
- Aquamantys System
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medtronic Surgical Technologies
Surgical View, Shoulder Tip Pain
Evaluation of Low Pressure Pneumoperitoneum in Bariatric Surgery (ELOPES Study)
This is a prospective study whereby it involves patients who are planned for bariatric surgery. In the bariatric surgery procedure, pneumoperitoneum pressure will be the experimental aspect in this study.
- Conditions
- Surgical View, Shoulder Tip Pain, Abdominal Pain
- Trial name
- NCT03179111
- Testing
- Pneumoperitoneum Pressure
- Where
- Malaysia
- Volunteers
- 94 people
- Sponsor
- Universiti Putra Malaysia
Pneumoperitoneum
Influence of Posture and Gas Insufflation on Perioperative Lung Function
Perioperative airway resistance and lung function are evaluated perioperatively in patients, who undergo surgical procedures in different postures and with or without gas insufflation into the peritoneal cavity.
- Trial name
- NCT00948571
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Kliniken Essen-Mitte
Cervical Vertebrae, Single
The Comparison Between the Stand-alone Cage and the Autologous Iliac Bone Graft/Anterior Plating in the Single-level Surgical Treatment of the Cervical Spine
The use of plate in addition to autologous bone is better then stand alone cage fusion regarding fusion rate and segmental lordosis.
- Conditions
- Cervical Vertebrae, Single, Degenerative Disease
- Trial name
- CAP_2014 (NCT02030899)
- Testing
- Cage fusion, Plate fusion
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Gynecologic Surgical Procedures
Rectus Sheath Block for Analgesia After Gynecological Laparotomy
Thirty subjects undergoing laparotomy for Gynecologic oncology surgery will be prospectively enrolled and will receive a bilateral rectus sheath block (RSB) under ultrasound guidance using 133 mg liposomal bupivacaine and 20 ml…
- Trial name
- NCT06575699
- Testing
- Rectus sheath block, Thoracic Epidural Analgesia, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Duke University
Open Heart Surgery Patients
Patient Education by Mobile Application
Cardiovascular diseases are among the important health problems that cause mortality and morbidity both in our country and in the World (Sidar vd 2013).
- Trial name
- NCT05094063
- Testing
- patient education by mobile application
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Betul Zeynep Yildiz
Aneurysm Aortic, Vascular Diseases
F-BEVAR vs Open Surgery for Complex Abdominal Aortic Aneurysm
The aim of the present study was to investigate outcomes of a propensity matched series of patients treated with F-BEVAR and open surgery repair for complex abdominal aortic aneurysm in two aortic high-volume centres.
- Trial name
- NCT05247944
- Testing
- Fenestrated and branched endovascular aortic repair (F-BEVAR), Open repair
- Volunteers
- 278 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cardiac Surgical Procedures
Pharmacokinetics and Pharmacodynamics of Pentobarbital in Neonates, Infants, and Children Following Open Heart Surgery
This medication is used for procedural sedation and sedation for diagnostic imaging. The purpose of this study is to find out what happens to pentobarbital in the body after it is given to children who have had heart surgery.
- Trial name
- NCT00577434
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Children's Hospital of Philadelphia
Hysterectomy, Tubal Excision
Etoricoxib for Routine Post-operative Pain Prophylaxis in Laparoscopic Surgery
The aim of this trial is to compare if a single dose of oral etoricoxib 120 mg will have equal post-operative analgesic efficacy as an optimal regiment of intravenous ketorolac 30 mg + 30 mg during the first 18 hours (+/- 1 hour)…
- Conditions
- Hysterectomy, Tubal Excision, Ovariectomy, Postoperative Pain
- Trial name
- NCT00373464
- Testing
- etoricoxib
- Where
- Norway
- Volunteers
- 126 people
- Sponsor
- Ullevaal University Hospital
Chronic Periodontitis
The Adjunctive Effect of Probiotics to Non Surgical Treatment of Chronic Periodontitis
Evaluation of clinical and microbiological effect of lactobacillus reuteri probiotics.
- Trial name
- NCT04697199
- Testing
- Lactobacillus Reuteri Oral Drops, Scaling and root planing
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Tanta University
Breast Cancer
Establishment and Clinical Application of Precise SLNB System in Breast Cancer: a Randomized, Multicenter, Controlled Study
The investigatorsconduct the precise sentinel lymph node biopsy using preoperative computed tomographic lymphography in breast cancer.
- Trial name
- NCT03857932
- Testing
- Participants receive SLNB as well as non SLNs resection
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shandong University
Periodontal Bone Loss, Periodontal Pocket
Treatment of Intraosseous Periodontal Defects With Hyaluronic Acid
The aim of the present investigation will be evaluate the healing of periodontal intraosseous defects following Minimally Invasive Non Surgical Debridement (MINSD) and application of a hyaluronic acid-based gel, compared to MINSD…
- Trial name
- NCT05188898
- Testing
- MINSD and Hyaluronic acid, MINSD
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Federico II University
Surgical Wound, Wound Dehiscence, Surgical
Prophylactic Negative Pressure Wound Therapy for High Risk Laparotomy Wounds. A Randomized Prospective Clinical Trial.
Negative pressure wound closure technique (NPWT) has been widely introduced in different clinical settings. Most of the studies report it as an effective and cost-effective method to treat complicated surgical wounds or even open…
- Conditions
- Surgical Wound, Wound Dehiscence, Surgical, Surgical Site Infection, Dehiscence of Internal Surgical Wound
- Trial name
- NCT03716687
- Testing
- Prophylactic negative pressure wound dressing after laparotomy
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- St. Borbala Hospital
Systemic Inflammatory Response Syndrome, Sepsis
Impact of Vitamin D Supplementation on Hepcidin Levels and Transfusion Requirements in Surgical and Septic Patients
Acute inflammation induced by surgery and sepsis is complicated by the development of iron-restricted anemia due to the up-regulation of hepcidin.
- Conditions
- Systemic Inflammatory Response Syndrome, Sepsis, Surgical Injuries
- Trial name
- DEHEPTRA (NCT03001687)
- Testing
- enteral supplementation with vitamin D, blood collection 3mL
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Pincer Nail
Reconstructive Surgical Approach for Pincer Nail
A prospective design that studies the effects of a new technique for the treatment of pincer nails. The technique consists of a flattening of the bone of the distal phalanx with a frontal skin lifting that is performed in…
- Trial name
- NCT02939521
- Testing
- Surgery
- Volunteers
- 10 people
- Sponsor
- Clínica María del Mar Ruiz
Tricuspid Regurgitation
Surgical Treatment of Tricuspid Valve Regurgitation in Patients With Cardiac Implantable Electronic Devices: Long Term Results
Old trials aimed to evaluate Implantable Cardioverter-Defibrillator (ICD) safety and efficacy demonstrated a meaningful decreased rates of sudden death but an increased rate of hospitalization for heart failure .
- Trial name
- NCT05774821
- Testing
- Tricuspid valve surgery
- Where
- Italy
- Volunteers
- 151 people
- Sponsor
- Michele De Bonis
Glioblastoma, GBM
Surgical Nivolumab And Ipilimumab For Recurrent GBM
This research trial is studying the safety and effectiveness of nivolumab in combination with ipilimumab and surgery when used in the treatment of recurrent glioblastoma.
- Conditions
- Glioblastoma, GBM, Glioblastoma Multiforme, Grade IV Astrocytoma
- Trial name
- NCT04606316
- Testing
- Nivolumab, Ipilimumab, Surgery
- Where
- 3 sites in United States
- Volunteers
- 63 people
- Sponsor
- Gilbert Youssef
Drainage, Spinal (Fusion) Surgery
ESTIMATION OF INCREASED SURGICAL DRAINAGE OUTPUT FOLLOWING THORACOLUMBAR SURGERY
In a study involving neurosurgeons worldwide, it was reported that most surgeons preferred the use of drains (186, 80.5%) and subfascial drains (169, 73.2%), with 52.87% of surgeons discontinuing drains based on time and 27.7%…
- Trial name
- NCT07390058
- Volunteers
- 326 people
- Sponsor
- AKİF BULUT
Chronic Periodontitis
RELATIONSHIP BETWEEN INITIAL PROBING DEPTH AND CHANGES IN CLINICAL PARAMETERS FOLLOWING NON-SURGICAL PERIODONTAL TREATMENT IN CHRONIC PERIODONTITIS PATIENTS
Aim: The aim of this study was to evaluate the relationship between initial probing depth (IPD) and changes in clinical parameters following non-surgical periodontal treatment (NPT) in chronic periodontitis patients.
- Trial name
- NCT02861326
- Testing
- Gracey Curettes
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Marmara University
Diabetic Foot Osteomyelitis
A Feasibility Trial to Investigate the Safety and Between-group Effect Size of STIMULAN VG and Standard of Care (SoC) in Participants With Diabetic Foot Osteomyelitis
The purpose of this trial is to evaluate the safety and between-group effect size of STIMULAN VG compared to SoC treatment in patients with diabetic foot osteomyelitis (DFO).
- Trial name
- BLADE-VG2 (NCT05539963)
- Testing
- STIMULAN VG, Systemic Antibiotics
- Where
- 10 sites in United States
- Volunteers
- 61 people
- Sponsor
- Biocomposites Ltd