Clinical trials: Surgical Anesthesia, open to volunteers
Acute Kidney Injury, Surgery Complications
Real-Time Acute Kidney Injury Perioperative Prediction Clinical Trial
This investigator-initiated, pragmatic trial evaluates whether displaying a machine learning (ML)- derived perioperative AKI risk score-alone or paired with an interruptive Best/Our Practice Advisory (BPA/OPA)-improves…
- Conditions
- Acute Kidney Injury, Surgery Complications, Anesthesia
- Trial name
- ML-AKI (NCT07604662)
- Testing
- EHR-Embedded AKI Risk Score, EHR-Embedded AKI Risk Score with Best Practice Advisory
- Where
- United States
- Volunteers
- 25,518 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Perioperative Care, EEG Power Spectra
Extended Emergence Strategy on Post-Anesthesia Care Unit Events After Outpatient Orthopedic Surgery
The goal of this clinical trial is to learn if an extended emergence from anesthesia can improve recovery room (Post-Anesthesia Care Unit or PACU) outcomes in lower-leg or foot surgery with nerve blocks.
- Conditions
- Perioperative Care, EEG Power Spectra, Delirium - Postoperative
- Trial name
- PACU-EMERGE (NCT07533370)
- Testing
- Standard of Care EEG-Guided Emergence, Extended EEG Emergence Trajectory
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Harrison Shong-Wen Chow
Caudal Epidural Anesthesia, Erector Spinae Plane Block
Comparison of Erector Spinae Plane Block and Caudal Block in Pediatric Patients Aged 1 to 8 Years Undergoing Lower Abdominal Surgery
In routine pediatric surgical practice, lower abdominal surgeries are commonly performed. Inadequate control of postoperative pain can hinder functional recovery and may lead to negative behavioral changes as well as parental…
- Conditions
- Caudal Epidural Anesthesia, Erector Spinae Plane Block, Pediatric
- Trial name
- NCT07426939
- Testing
- caudal block, Erector Spinae Plane Block
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Stress, Stress and Burnout
Deep Relaxation Using Virtual Reality Intervention Before Surgery for Healthcare Professionals Working in the Operating Room
The goal of this clinical trials is to primary learn if deep relaxation using Virtual Reality (VR) compared to a low stimulus environment can lower perceived and measured stress in healthcare professionals working in the…
- Conditions
- Stress, Stress and Burnout, Stress Biomarkers
- Trial name
- DEEP_VR (NCT07470697)
- Testing
- Virtual Reality intervention, Low Stimulus Environment
- Where
- 2 sites in Denmark, Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Prostate Cancer, Adverse Effects Surgery
TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia.
- Conditions
- Prostate Cancer, Adverse Effects Surgery, MRI, Ultrasound
- Trial name
- TPF-LITT (NCT05698576)
- Testing
- TRANBERG® Transperineal Fusion Laser--Induced Thermal Therapy of Prostate Cancer (TPF-LITT)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Urological Research Network, LLC
Postoperative Pain, Emergence Delirium
Effect of Preoperative Fasting Duration on Postoperative Pain and Emergence Agitation in Pediatric Patients Undergoing Urogenital Surgery
This study aims to evaluate the effect of preoperative fasting duration on postoperative pain and emergence agitation in pediatric patients undergoing urogenital surgery.
- Conditions
- Postoperative Pain, Emergence Delirium, Emergence Agitation
- Trial name
- NCT07552259
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Sore Throat After Thyroid Surgery
Transcutaneous Electrical Acupoint Stimulation on Postoperative Pharyngeal Pain
Thyroid surgery is a common type of surgery in thyroid and breast surgery, mainly used to treat benign and malignant thyroid diseases.
- Trial name
- NCT07117123
- Testing
- Transcutaneous electrical acupoint stimulation, No electrical stimulation
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Cognitive Impairment, Cognitive Impairment, Mild
Cognitive Assessment And Post-Operative Complications After Surgery: Linking Anaesthesia And Risk
Many older people can experience confusion, memory problems, or a decline in their thinking after major surgery. These problems are sometimes called 'postoperative neurocognitive disorders' or PND and can affect recovery and a…
- Conditions
- Cognitive Impairment, Cognitive Impairment, Mild, Cognitive Impairment, Progressive, Anesthesia
- Trial name
- CAPSULAR (NCT07470216)
- Testing
- Montreal Cognitive Assessment, biomarkers
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Opioid Consumption, Postoperative, Pain, Postoperative
Comparison of Pain Relief Methods for Hip Surgery: A Study on Two Different Nerve Block Techniques
This prospective randomized comparative study aims to compare the analgesic efficacy of pericapsular nerve group block (PENG) and lumbar erector spinae plane block (L-ESP) groups to relieve postoperative pain in participants over…
- Conditions
- Opioid Consumption, Postoperative, Pain, Postoperative, Nerve Block, PENG Block
- Trial name
- NCT06821516
- Testing
- Evaluation of the postoperative analgesic effectiveness of PENG block in participants undergoing total hip arthroplasty under spinal anesthesia, Evaluation of the postoperative analgesic effectiveness of lumbar erector spinae block in participants undergoing total hip arthroplasty under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Lower Limb Surgeries
Effect of Height Based vs Conventional Dose of Spinal Anesthesia in Lower Limb Surgeries
This study aim is to compare height based dose of spinal anesthesia vs conventional dose. Hypothesis is height based dose has less hemodynamics changes compared to conventional dosing.
- Trial name
- NCT07751835
- Testing
- Height based dose of hyperbaric bupivacaine 0.5%
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
Post Spinal Anesthesia Shivering
The Effect of Different Doses of Dexamethasone on Post Spinal Anesthesia Shivering
The precise etiology of post-spinal anesthesia shivering (PSAS) is not fully understood. The incidence ranges between 20 to 80%.
- Trial name
- NCT06999070
- Testing
- Dexamethasone 0.1mg/kg, Dexamethasone 0.3mg/kg
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anesthesia
Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block…
- Trial name
- EKAT-TeleTPS (NCT03747146)
- Testing
- Continuous Adductor Canal Catheter (ACC)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Throid Surgery, Airway Complication of Anaesthesia
Comparison of the Effects of Total Intravenous Anaesthesia With Target-Controlled Infusion (TCI) and Inhalation Anaesthesia on Airway Complications During Extubation and in the Early Postoperative Period in Thyroidectomy Surgery
Thyroid surgery is one of the most complex operations in the head and neck region due to its close relationship with anatomical structures and the high risk of recurrent laryngeal nerve injury.
- Conditions
- Throid Surgery, Airway Complication of Anaesthesia, Coughing Responses at Tracheal Extubation, Laryngospasm on Emergence
- Trial name
- NCT07325669
- Testing
- tıva
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- dilara gocmen
Anesthesia, Analgesia
Genetic Variants and Perioperative Morbidity and Mortality
Prospective association study to analyse perioperative patients' outcome. Outcome comprises intraoperative and postoperative complications e.g.
- Conditions
- Anesthesia, Analgesia, Surgical Procedure, Operative
- Trial name
- NCT02124499
- Where
- Switzerland
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Chronic Cough, Video-assisted Thoracoscopic Surgery (VATS)
A Prospective, Randomized, Double-blind Study on the Effects of Different Anesthesia Strategies on Postoperative Cough in Patients Undergoing Video-assisted Thoracoscopic Surgery.
This study aims to systematically evaluate the effects of different anesthesia methods on postoperative chronic cough in lung cancer patients undergoing video-assisted thoracoscopic lung resection (VATS), and to clarify the…
- Trial name
- Chronic cough (NCT07190664)
- Testing
- Patients were randomly grouped
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Regional Anesthesia, Video-assisted Thoracoscopic Surgery (VATS)
Ultrasound-Guided Erector Spinae Plane Block Versus Thoracoscopically-Guided Intercostal Nerve Block in Video-Assisted Thoracoscopic Surgery
Effective postoperative pain management is essential after thoracic surgery. Insufficient pain control may impair breathing and coughing, increasing the risk of pulmonary complications such as collapsed lungs (atelectasis) or…
- Conditions
- Regional Anesthesia, Video-assisted Thoracoscopic Surgery (VATS), Erector Spinae Plane Block, Intercostal Nerve Block
- Trial name
- NCT07535697
- Testing
- Anesthesiological, Ultrasound-Guided "Erector Spine Plane Block" (ESPB), Surgical, Thoracoscopically-Guided "Intercostal Nerve Block" (ICNB)
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Sana Klinikum Offenbach
Arthroplasty Replacement, Knee, Anesthesia Conduction
Migration Rate for Continuous Adductor Canal Block Catheters After Primary Total Knee Arthroplasty Surgery: a Comparison Between Two Insertion Techniques
Continuous adductor canal block (CACB) is becoming increasingly popular for providing postoperative analgesia following knee arthroplasties.
- Trial name
- ISAFExOOPS (NCT07681622)
- Testing
- ISAFE technique for adductor canal catheter insertion, OOPS technique
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Ultrasound Guided Nerve Block, Anesthesia , Analgesia
Comparative Study Between Ultrasound Guided Regional Anesthesia for Awake Tympanoplasty Surgery vs General Anesthesia
The aim of this study to evaluate efficacy of ultrasound guided regional anesthesia in performing awake tympanoplasty surgery versus traditional general anesthesia
- Trial name
- NCT07275450
- Testing
- Ultrasound-guided regional anesthesia group, Control group
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Inferior Vena Cava, Collapsibility Index
Preoperative Evaluation of IVC Collapsibility Index and Caval Aorta Index After Induction of General Anesthesia
This study aims to assess the accuracy, repeatability, and reproducibility of preoperative evaluation of Inferior Vena Cava (IVC) collapsibility index and caval aorta index for prediction of hypotension after induction of general…
- Conditions
- Inferior Vena Cava, Collapsibility Index, Caval Aorta Index, Induction
- Trial name
- NCT07399093
- Testing
- Inferior vena cava collapsibility index, Caval Aorta Index
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
EKG-QT Prolongation
Effect of Methadone and Hydromorphone on the QT Interval After Anesthesia and Surgery
A number of drugs used in the perioperative period may cause prolongation of the QT interval on the electrocardiogram (EKG). These drugs include inhalational agents, antiemetic agents, pain medications, and drugs used to reverse…
- Trial name
- NCT03893734
- Testing
- methadone, Hydromorphone
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Endeavor Health