Clinical trials: Surgery Scheduled
Infants Aged 0 Days to 13 Months Scheduled for Elective Surgery
Effect of Pressure Support Ventilation During Anesthetic Emergence on Postoperative Atelectasis in Infant
Atelectasis occurs in patients of all ages who receive mechanical ventilation under general anesthesia, and although fatal cases are rare, it is known as a cause of postoperative hypoxia or fever.
- Trial name
- NCT05373589
- Testing
- conventional ventilation, group C, pressure support, group PS
- Where
- South Korea
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Pre-operative Haemorrhagic Risk
Pre-operative Haemorrhagic Risk Screening, Using a Standardized Questionnaire Before Scheduled Surgeries
"This is not a validation study of a questionnaire. This is a multicenter diagnostic study, assessing the sensitivity and specificity of a simple structured questionnaire, to identify patients requiring further haemostatic…
- Trial name
- HEMORISQ (NCT02617381)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cerebral Aneurysm Unruptured, Iron Deficiency Anemia
Effect of Preoperative Intravenous Ferric Carboxymaltose for Clipping Surgery
Hypothesis: Correction of preoperative anemia can reduce the need for intra-/postoperative RBC transfusions and can improve surgical outcomes.
- Conditions
- Cerebral Aneurysm Unruptured, Iron Deficiency Anemia, Surgery
- Trial name
- PICASA (NCT04616092)
- Testing
- FEFINJECT
- Volunteers
- 130 people
- Sponsor
- Seoul National University Hospital
Surgical Site Infection
Chlorhexidine Cloths to Reduce Surgical Site Infection in Cesarean Deliveries
Pregnancy-associated infection represents a major cause of maternal morbidity and mortality. Cesarean delivery is the most common major surgical procedure and is associated with a rate of surgical site infection (SSI) that is…
- Trial name
- NCT04202471
- Testing
- Chlorhexidine Cloth
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Surgical Procedure, Unspecified, Pain, Postoperative
Continuous Infusions vs Scheduled Bolus Infusions
The goal of the study is to compare continuous infusions and scheduled bolus infusions for peripheral nerve blocks and their effect on post-surgical pain.
- Trial name
- NCT03230565
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Stanford University
Difficult Airway
Incidence and Contributing Anthropometric Factors of Difficult Airway in Pediatric Surgical Patients
The goal of this prospective, observational study is to identify predictors of difficult mask ventilation, direct laryngoscopy and intubation in pediatric patients scheduled for elective surgery and to determine their incidence.
- Trial name
- NCT06000267
- Testing
- Intubation
- Where
- Serbia
- Volunteers
- 500 people
- Sponsor
- University Childrens Hospital Belgrade
Conjunctival Bacterial Flora
Effectiveness of Topical 0.5% Levofloxacin to Reduce the Conjunctival Bacterial Flora Before Intraocular Surgery
The purpose of this study is to determine whether additional topical application of 0.5% levofloxacin is more effective in reducing the load of the conjunctival bacterial flora in patients scheduled for intraocular surgery than…
- Trial name
- NCT00491049
- Testing
- 0.5% levofloxacin eye drops
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Severe Obesity Scheduled for Bariatric Surgery
Cardiometabolic Risk Factor Management and Adherence to Antihypertensive Therapy in Patients With Severe Obesity Prior to Bariatric Surgery: a Prospective Longitudinal Cohort Study
Patients with severe obesity frequently exhibit elevated cardiovascular risk. Contributing factors could be inadequate recognition and subsequent management of cardiovascular risk factors, and non-adherence to cardiovascular…
- Trial name
- NCT07441304
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Universität des Saarlandes
Bony Defect
Scheduled Autologous PRP Guided Injection in the Maxillary Bony Defects
Scheduled autologous platelet-rich plasma guided injection is done in critical-sized maxillary bony defects after surgical excision of non- malignant lesions.
- Trial name
- NCT07108933
- Testing
- Autologous platelet-rich plasma
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Horus University
Obstructive Sleep Apnea, Vascular Aneurysm
OSA as a Remote Ischemic Preconditioning in Vascular Surgery
Ischemia and reperfusion (I/R) injury during abdominal aortic aneurysm (AAA) repair is inevitable and may lead to postoperative multi-organ failure.
- Conditions
- Obstructive Sleep Apnea, Vascular Aneurysm, Ischemia Reperfusion Injury
- Trial name
- NCT04630535
- Testing
- aorto-bifemoral bypass surgery
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Peritoneal Carcinomatosis, Ovarian Cancer
A Study of Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and Interval Debulking Surgery
This is a Phase 2, controlled, randomised, parallel assignment, open label, multicentre study to evaluate efficacy and safety of a single intraperitoneal injection of Radspherin® in patients with primary advanced high-grade…
- Trial name
- NCT06504147
- Testing
- Radspherin
- Where
- 10 sites in United States, Belgium and 4 more
- Volunteers
- 114 people
- Sponsor
- Oncoinvent Solutions AS
Hemodynamics
Fluid ORiented Therapy for yoUNg Asa 1patients
In this retrospective analysis investigators will study the effects of using a minimally invasive hemodynamic monitoring (FloTrac-Edwards) on postoperative outcomes.
- Trial name
- NCT03090399
- Testing
- FloTrac
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Essential Tremor
Long-Term Transcutaneous Stimulation and Essential Tremor: A PET Study
Essential tremor (ET) is the most common movement disorder in the United States and affects up to 5% of the population. ET patients experience involuntary shaking of the hands, head and/or voice that can range from mildly…
- Trial name
- NCT03778060
- Testing
- Cala TWO stimulator
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Delirium in Old Age, Delirium
PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients
Our objective is to find an effective prophylactic intervention by evaluating IV acetaminophen's impact in reducing the frequency of postoperative delirium, one of the most common and detrimental complications of cardiac surgery…
- Conditions
- Delirium in Old Age, Delirium, Coronary Artery Disease
- Trial name
- PANDORA (NCT04093219)
- Testing
- IV acetaminophen
- Where
- 10 sites in United States
- Volunteers
- 901 people
- Sponsor
- Beth Israel Deaconess Medical Center
Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery, Osteoarthritis (OA) of the Knee
Does the Use of Patient Specific Instrumentation Improve Outcomes in Knee Arthroplasty Surgery for Osteoarthritis When Compared to Standard Posterior Referenced Instrumentation?
The goal of this randomized study is to see if using patient-specific instruments (PSI) during total knee replacement surgery improves outcomes compared to standard instruments.
- Trial name
- PRIPSI (NCT06720012)
- Testing
- Patient specific instrumentation (PSI), Conventional instruments, Cemented Total Knee Arthroplasty
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Vastra Gotaland Region
Prostate Cancer
A Phase 2 Study With MIP-1404 in Men With High-Risk PC Scheduled for RP and EPLND Compared to Histopathology
This was a multicenter, multi-reader, open-label, Phase 2 study assessing the safety and performance characteristics of MIP 1404 imaging in the detection of prostate gland and pelvic lymph node cancer.
- Trial name
- NCT01667536
- Testing
- Drug: 99mTc-MIP-1404
- Where
- 35 sites in United States, Belgium and 6 more
- Volunteers
- 105 people
- Sponsor
- Molecular Insight Pharmaceuticals, Inc.
Both Benign and Malignant Liver Mass
Accuracy and Reliability of GSA for Remnant Liver Function
Preoperative evaluation of future remnant liver function is critical for patients undergoing hepatic surgery. Overestimation of the remnant liver function can lead to life-threatening postoperative hepatic failure, and its…
- Trial name
- GSA (NCT02013895)
- Testing
- 99mTc-GSA
- Where
- Japan
- Sponsor
- Kochi University
Inguinal Hernia, Postoperative Pain
Preoperative Etanercept Before Inguinal Hernia Surgery
Inguinal hernia repair is one of the most frequently performed operations in young men. Persistent pain after inguinal surgery represents a significant cause of disability, occurring in between 15%-35% of cases.
- Trial name
- NCT00825344
- Testing
- Etanercept, Saline
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Johns Hopkins University
Abdominal Surgery
Preoperative Nutritional Assessment for Predicting Complications Risk in Patients Undergoing Abdominal Surgery
Predictive Value of Various Nutritional Screening and Assesment Tools and a Surgery Scoring System (POSSUM Score) for Predicting Postoperative Complications in Patients Scheduled for Abdominal Surgery.
- Trial name
- NCT03719508
- Where
- Greece
- Volunteers
- 450 people
- Sponsor
- Evangelismos Hospital
Cognitive Change
Preoperative Risk Factors and Perioperative Neurocognitive Disorders
Perioperative neurocognitive disorders (PND's) remain an important complication after surgery. After many years of speculating about the etiology of this complication, currently studies are pointing to an inflammatory cascade…
- Trial name
- NCT03805685
- Testing
- Non-Cardiac Surgery
- Where
- Belgium
- Volunteers
- 38 people
- Sponsor
- Université Libre de Bruxelles