Clinical trials: Surgery, Oral
Gingival Recession
Platelet Rich Fibrin in the Treatment of Palatal Wounds
In this study it will be investigated the usefulness of Platelet-Rich Fibrin (PRF) on in the epithelialized connective tissue graft palatal donor site healing acceleration and in the patient's morbidity reduction.
- Trial name
- NCT02438046
- Testing
- Palatal wound bandage
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Edentulous Jaws
Computer Assisted Implant Surgery and Immediate Loading
Purpose: The aim of this study was to analyze the clinical and radiographic outcomes of 23 edentulous jaws treated with 3D software planning, guided surgery, immediate loading and restored with Cad-Cam Zirconia and titanium full…
- Trial name
- NCT01866696
- Testing
- oral implants
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Università degli Studi di Sassari
Periodontal Inflammation, Alveolar Bone Loss
The Effect of Non-surgical Periodontal Treatment on Dickkoff-1 and Secreted Frizzled Related Protein-5 Levels
Periodontitis is a condition that is defined by microbial-associated, host-induced inflammation, which ultimately results in the loss of periodontal attachment.Periodontal clinical parameters are the most reliable indicators of…
- Conditions
- Periodontal Inflammation, Alveolar Bone Loss, Periodontal Diseases
- Trial name
- NCT06727929
- Testing
- Collection of gingival crevicular fluid, ELISA
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Periodontal Bone Loss
Decortication With Calcium Phosphosilicate Putty in the Treatment of Non-contained Intrabony Periodontal Defects
To overcome the disadvantage of complex morphology and availability of less favorable support to retention of graft and clot stabilization in 1-, 1-2-wall periodontal defects, it was hypothesized that placement of CPS putty…
- Trial name
- NCT03435757
- Testing
- OFD+IMP+CPS, OFD+IMP
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession, Mucogingival Surgery
Effects of Low-Level Laser Therapy and Hyaluronic Acid After Free Gingival Graft
The goal of this randomized clinical trial was to learn whether low-level laser therapy or hyaluronic acid application improves healing after free gingival graft surgery in adults with insufficient keratinized gingival tissue in…
- Trial name
- NCT07751211
- Testing
- Topical Hyaluronic Acid Gel, Low-Level Laser Therapy, Free Gingival Graft Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Altinbas University
Periodontitis
Effect of Dietary Intake of Dried Whole Food Concentrates (Juice Plus) on Clinical Outcomes Following Periodontal Therapy: A Pilot Study
There are 3 hypotheses to be tested: 1. That daily supplementation with Juice Plus+ will significantly improve treatment outcomes over placebo supplementation, at 3-months post-therapy, when used as an adjunct to conventional…
- Trial name
- BHAM-NSA-05-01 (NCT00952536)
- Testing
- Daily Juice Plus+ with vegetable & fruit & berry capsule
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Birmingham Community Healthcare NHS
Periodontitis, Bone Resorption
Sodium Alendronate in Non Surgical Periodontal Therapy
In the past few years, studies have evaluated the effect of systemic use of sodium alendronate, especially in the treatment of structural bone defects caused by periodontal diseases.
- Trial name
- SANSPET (NCT02470611)
- Testing
- Sodium alendronate
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Federal University of Minas Gerais
Bowel Surgery, Emergency Abdominal Surgery
COMPARATIVE OUTCOME OF EARLY AND STANDARD ORAL FEEDING AFTER EMERGENCY BOWEL SURGERY
Informed consent will be obtained from patients or their legal representatives in cases where the patient is unconscious. Patient information, including names, ages, gender, smoking history, comorbidities, and the indication for…
- Conditions
- Bowel Surgery, Emergency Abdominal Surgery, ERAS
- Trial name
- NCT07047729
- Testing
- Early oral feeding, Standard oral feeding
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dr Hamail Khanum
Neuropathic Pain Induced by Mastectomy
Pain and Magnesium
In breast cancer patients undergoing a mastectomy, the aim of this study is to evaluate if the magnesium administered for 6 weeks starting two weeks before the surgery induces a decrease of pain intensity one month…
- Trial name
- NCT03063931
- Testing
- Magnesium: Magnésium UPSA Action Continue®
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Rheumatoid Arthritis, Periodontitis
Evaluation of Non-surgical Periodontal Therapy in Patients With Rheumatoid Arthritis
Some clinical and epidemiological studies have revealed a high prevalence of periodontitis and tooth loss in patients with rheumatoid arthritis.
- Trial name
- NCT02379975
- Testing
- Non-surgical Periodontal Therapy
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- CAIO VINICIUS GONÇALVES ROMAN TORRES
Hypoxemia
Capnography Monitoring During Intravenous Conscious Sedation Sedation With Midazolam for Oral Surgery
Dentists use sedation to help patients accept difficult procedures and to relieve anxiety. During sedation, the well-being of the patient is monitored by the dental team.
- Trial name
- NCT01949012
- Testing
- Capnography
- Where
- Ireland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University College Cork
Peridontal Disease, Furcation Defects
PRF Versus Emdogain for Class II Furcation Defects of Mandibular Molars
This study evaluated the regenerative potential of platelet-rich fibrin (PRF) compared with enamel matrix derivative (Emdogain®) in the surgical treatment of Class II (F2) furcation defects of mandibular molars.
- Trial name
- NCT07841301
- Testing
- Platelet rich fibrin, Emdogain
- Where
- Bulgaria
- Volunteers
- 21 people
- Sponsor
- Medical University of Sofia
Saliva, Cortisol
Comparison of Saliva Biomarkers in Two Different Geographical Regions of Turkey
Periodontitis is a multifactorial, chronic inflammatory disease caused by many factors such as pathogenic microorganisms, host response, environmental and systemic factors.
- Conditions
- Saliva, Cortisol, Smoking, Tobacco, Periodontal Bone Loss
- Trial name
- NCT06809439
- Testing
- Non-Surgical Intervention, Saliva Collection (Baseline), Probing
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Karabuk University
İron Deficiency Anemia, Liposomal Iron Replacement
Liposomal vs Conventional Oral Iron After Sleeve Gastrectomy
Low-dose liposomal iron (17-34 mg elemental/day) was compared with standard conventional oral iron (100-200mg elemental/day) in the treatment of iron deficiency anemia following sleeve gastrectomy.
- Conditions
- İron Deficiency Anemia, Liposomal Iron Replacement, Conventional Iron Replacement
- Trial name
- anemia (NCT07366502)
- Testing
- Liposomal Iron, conventional oral iron
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Medeni Şermet
Morphine Consumption
The Effect of Intraoperative Dexmedetomidine on Postoperative Morphine Requirements After Breast Cancer Surgery
Dexmedetomidine is an α2 receptor agonist with sedative and analgesic properties. In previous reports, dexmedetomidine improves smoothness of postoperative recovery and reduces intraoperatory imflammatory responses.
- Trial name
- NCT04454515
- Testing
- Dexmedetomidine
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Mechanical Aortic and/or Mitral Valve Replacement Operation
Patient International Normalised Ratio (INR) Self-Testing Program
The aims of the study are to prove correlation between laboratory and patient self-testing (PST) measurements, estimation of INR variability within a target therapeutic zone and frequency of hemorrhagic and/or thromboembolic…
- Trial name
- NCT00925197
- Testing
- INR self-testing program
- Volunteers
- 206 people
- Sponsor
- University Hospital, Clermont-Ferrand
Anesthesia, Cardiac Surgery
Oral and Intravenous Methadone for Analgesia in Cardiac Surgery
The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac…
- Trial name
- NCT06720415
- Testing
- Oral methadone, immediately prior to transport, Intravenous methadone
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Mayo Clinic
Periodontitis, Periodontitis Stage I
Chlorhexidine and Zinc in Non-Surgical Periodontal Therapy
Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth and is associated with both local tissue destruction and systemic inflammatory responses.
- Conditions
- Periodontitis, Periodontitis Stage I, Periodontitis Stage II
- Trial name
- CHX-Zn (NCT07517991)
- Testing
- Chlorhexidine and zinc application, Scaling and root planing with distilled water
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ataturk University
Gingival Enlargement
Evaluation of Healing Process After Laser Asissted Gingivectomy Techniques
Objective: The aim of this study was to evaluate and determine clinical and biochemical comparison of 3 different methods including Er:YAG laser, diod laser, and conventional techniques.
- Trial name
- NCT04304391
- Testing
- Resective Gingival Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Peri-Implantitis
Follow-Up After Surgical Treatment of Peri-implantitis
The objective of this prospective clinical study was to evaluate the 3-year outcomes of anti-infective surgical treatment of peri-implantitis when a regular supportive peri-implant therapy (SPIT) programme was followed.
- Trial name
- NCT02860208
- Testing
- 3 years follow-up
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Göteborg University