Clinical trials: Suicide
Haploidentical Stem Cell Transplantation
Suicide Gene Therapy Trial
Bone marrow or blood stem cell transplantation is used to treat a wide range of life-threatening conditions. T lymphocytes carried in the graft have powerful beneficial effects and play a vital role in the eradication of…
- Trial name
- NCT01204502
- Testing
- HSVTK retrovirally-transduced donor T lymphocytes
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Suicide
Group ("Project Life Force") vs. Individual Suicide Safety Planning RCT
The management of suicide risk is a pressing national public health issue especially among Veterans. This grant consists of two arms: the novel treatment and treatment-as-usual.
- Trial name
- PLF (NCT03653637)
- Testing
- Project Life Force, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 294 people
- Sponsor
- VA Office of Research and Development
Suicide Prevention, User Experience
User Evaluation of Zelfmoord1813.be and Its Related Websites
Monitoring the availability and accessibility of suicide prevention information in Flanders remains crucial. In 2022, 1,024 people died by suicide in Flanders, and approximately 10,000 individuals required emergency care…
- Trial name
- NCT07071922
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University Ghent
Suicide, Attempted
Efficacy of EBPSI on Future Suicide Risk Among Adolescent Suicide Attempters
Our study is designed to study the efficacy of an Electronic based psycho-social intervention targeting healthy coping and problem solving skills to mitigate suicidal behaviour.
- Trial name
- NCT06474221
- Testing
- Electronic Based Psychosocial Intervention (EBPSI)
- Where
- 2 sites in India
- Volunteers
- 168 people
- Sponsor
- University of Pittsburgh
Suicide, Attempted
Male Suicide and Metacognition
Suicide is the act of killing oneself and accounts for one death every 40 seconds around the world. In the UK, over 75% of suicides are completed by men.
- Trial name
- MSM (NCT04796116)
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Greater Manchester Mental Health NHS Foundation Trust
Suicide and Self-harm, Emotion Regulation
Supplementing Brief Psychotherapy With a Mobile App
Suicide is among the leading causes of death worldwide, and the risk of suicide is highest in the period immediately following discharge from inpatient psychiatric care.1Importantly, despite the enormously elevated risk during…
- Trial name
- NCT05867316
- Testing
- Unified Protocol
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Rutgers, The State University of New Jersey
Suicidal Ideation
INternet-based Programmes FOR the Prevention of Suicidal Ideation in MEDical Students
Two programmes have been built to prevent suicidal ideation; one focuses on stress management based on cognitive and behavioural principles and the other on health promotion.
- Trial name
- InforMed (NCT03949556)
- Testing
- Videos and/or SMS
- Where
- France
- Volunteers
- 2,544 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Suicidal Ideation, Major Depressive Disorder (MDD)
Understanding and Treating Suicidal Ideation With Ketamine
The goal of this clinical trial is to treat active suicidal ideation in individuals with Major Depressive Disorder (MDD) using ketamine and to understand suicidal ideation by examining biological mechanisms using magnetic…
- Trial name
- NCT06891300
- Testing
- ketamine hydrochloride
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- The Royal's Institute of Mental Health Research
Suicidal and Self-injurious Behavior, Linkage to Care
An Adaptive Intervention to Increase Engagement to Community-Based Care After an ED Admission
The goal of this study is to develop a feasible brief, family-based adaptive intervention, via SMART design, for youth with suicidal and non-suicidal self-injurious behavior (SSIB) to increase community-based mental health (MH)…
- Trial name
- ED_SMART (NCT07092345)
- Testing
- adaptive intervention
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Rhode Island Hospital
Suicide Prevention, Help-Seeking Behavior
Healthcare for Men with Suicidal Thoughts: Needs Assessment
The aim of the current project is twofold, namely 1. To gain insight into needs related to help-seeking among men with (previous) suicidal thoughts (STUDY 1).
- Conditions
- Suicide Prevention, Help-Seeking Behavior, Men
- Trial name
- KUJK2NEEDS (NCT06375200)
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- University Ghent
Suicide, Attempted
Effect of Telephone Follow-up on Repeated Suicide Attempt in Patients
Attempted suicide is a major public health problem, and the efficacies of current postvention protocols vary. The investigators evaluated the effectiveness of telephone follow-up of patients referred to an emergency psychiatric…
- Trial name
- EXBRAYAT (NCT02932709)
- Testing
- suicide attempt
- Where
- France
- Volunteers
- 876 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Sleep Problems, Suicidal Ideation
Sleep Treatment for Teens (RCT Phase)
The purpose of this research study is to compare (vs. treatment as usual) a brief (6-session), empirically supported, and highly disseminable version of digital (i.e., smartphone or web-based) cognitive behavioral therapy for…
- Conditions
- Sleep Problems, Suicidal Ideation, Suicidal Behavior
- Trial name
- NCT07303959
- Testing
- Sleepio, Treatment as Usual (TAU)
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
Depressive Disorder, Major, Adult Attention Deficit Hyperactivity Disorder
Clinical and Suicidal Features of Urban, Turkish Middle Age Depressive Patients With Comorbid ADHD
In the presence of attention deficit hyperactivity disorder (ADHD) together with additional psychiatric diseases, the treatment process and prognosis of both ADHD and psychiatric comorbidity are adversely affected.
- Conditions
- Depressive Disorder, Major, Adult Attention Deficit Hyperactivity Disorder, Suicide
- Trial name
- NCT03721588
- Testing
- Clinical interviews, psychometric scales were applied.
- Volunteers
- 96 people
- Sponsor
- Bozyaka Training and Research Hospital
Suicidal Crisis
Latin American Testing of the Inventory for Risk in Suicidal Crisis Syndrome (LATIR-SCS)
The goal of this observational validation study is to assess the psychometric properties of the Spanish versions of the Suicide Crisis Inventory-Revised (SCS-2) and the Suicidal Crisis Syndrome Checklist (SCS-C) in adults…
- Trial name
- LATIR-SCS (NCT07103850)
- Testing
- Suicidal Crisis Syndrome Checklist (SCS-C), Suicide Crisis Inventory-Revised (SCS-2)
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University Diego Portales
Insomnia, Physical Health Functioning
Efficacy of a Computerized Cognitive Behavioral Treatment for Insomnia: Increasing Access to Insomnia Treatment to Decrease Suicide Risk
Insomnia is major problem among Operation Enduring Freedom (OEF), Operation Iraqi Freedom (OIF), and Operation New Dawn (OND) Veterans.
- Conditions
- Insomnia, Physical Health Functioning, Mental Health Functioning
- Trial name
- Vets Sleep (NCT03366870)
- Testing
- Computerized Cognitive Behavioral Therapy for Insomnia, Sleep Education
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Suicidal Ideation, Suicide Attempt
Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial
This study outlines a randomized controlled trial evaluating two brief suicide-specific interventions for adolescents aged 12-17 who are hospitalized for suicidal ideation or attempts.
- Conditions
- Suicidal Ideation, Suicide Attempt, Safety Plan, Depression / Major Depressive Disorder
- Trial name
- NCT07628192
- Testing
- CAMS Brief Intervention, Stanley-Brown Safety Planning Intervention
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- The Cleveland Clinic
Suicide, Suicide, Attempted
Crisis Line Facilitation
This study is a randomized controlled trial (n = 301) of a new single-session intervention, called Crisis Line Facilitation (CLF), compared to an enhanced usual care condition on utilization of the Veterans Crisis Line and other…
- Conditions
- Suicide, Suicide, Attempted, Hospitals, Psychiatric
- Trial name
- CLF (NCT02459587)
- Testing
- Crisis Line Facilitation (CLF), Enhanced Usual Care (EUC)
- Where
- 2 sites in United States
- Volunteers
- 307 people
- Sponsor
- VA Office of Research and Development
PTSD, Suicidal Thoughts and Behaviors
Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study
This study will be the first to use brain imaging to explore how cannabis affects the brain and inflammation in U.S. military veterans with PTSD.
- Conditions
- PTSD, Suicidal Thoughts and Behaviors, PTSD Symptoms, Depressive Symptoms
- Trial name
- CNS (NCT07222306)
- Testing
- 1-(2-[+F]fluoroethyl)-L-tryptophan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wayne State University
Depression, Post Traumatic Stress Disorder
The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry
While effective interventions for depression exist, their success rates are unsatisfactory and their provision is haphazard. The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Depression Hub will improve…
- Conditions
- Depression, Post Traumatic Stress Disorder, Bipolar Disorder, Mood Disorder
- Trial name
- NCT02443636
- Where
- Canada
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Suicide
Developing Text-based Support for Parents of Adolescents After an Emergency Department Visit
The researchers seek to develop a text message intervention for caregivers of adolescents at elevated suicide risk following discharge from emergency department (ED) care.
- Trial name
- NCT05058664
- Testing
- A-F texting component, P-F texting component
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Michigan