Clinical trials: Suicidal Behavior, open to volunteers
Suicide Prevention, Suicidal Ideation
Co-creation of Tools for Children and Adolescents with Suicidal Thoughts And/or Behaviour
Evidence shows that there are very few evidence-based tools or interventions specifically targeting suicidality in children and adolescents.
- Conditions
- Suicide Prevention, Suicidal Ideation, Suicidal Behaviors
- Trial name
- Co-crea K&J (NCT06776328)
- Testing
- Tools
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Ghent
Sleep Disturbance, Sleep
Sleep and Circadian Interventions for College Students at High Risk of Suicide
The purpose of this study is to examine the extent to which delivering sleep and circadian focused interventions in addition to evidenced based psychiatric care for depression and suicide risk may contribute to decreasing suicide…
- Conditions
- Sleep Disturbance, Sleep, Depression, Suicide
- Trial name
- REST-UP (NCT07346014)
- Testing
- Sleep Feedback + Psychoeducation, Transdiagnostic Sleep and Circadian Intervention + Bright Light (TSC+), Triple Chronotherapy (TCT+)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Pittsburgh
Borderline Personality Disorder
SHame prOpensity in bOrderline Personality Disorder
Borderline Personality Disorder (BPD) is a common psychiatric disorder occurring in 2 to 6% of the population. 70% of patients with BPD do at least one Suicide Attempt (SA) in their lives.
- Trial name
- SHOO (NCT03994510)
- Testing
- Clinical and biological assessments - a 5 Years follow-up
- Where
- France
- Volunteers
- 688 people
- Sponsor
- University Hospital, Montpellier
Bipolar Disorder
Observation of Clozapine Treatment Safety in Bipolar Disorder.
The purpose of the registry is to record incidence of adverse events during treatment with clozapine in patients suffering from bipolar disorder.
- Trial name
- CloGD (NCT06011460)
- Testing
- Clozapine
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Gdansk
Sleep Disorder, Mental Health Issue
Improving Sleep in a Psychiatric Hospital
The purpose of this study is to examine effects of sleep promotion versus treatment as usual (TAU) on subjective, self-reported sleep while in inpatient psychiatric treatment, to examine effects of sleep promotion vs.
- Trial name
- NCT07010718
- Testing
- Scented Oil, Ear Plugs, Eye Mask
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center, Houston
Suicidal Ideation, Suicide Attempt
Attempted Suicide Short Intervention Program for Older Adults (ASSIP-OA): An Evaluation of a Psychosocial Intervention for Suicidal Adults Aged 65+
Older adults are sorely underrepresented in suicide prevention research, despite the fact that suicide rates are higher in this age group than in any other age group in Sweden and in many countries worldwide.
- Conditions
- Suicidal Ideation, Suicide Attempt, Suicide
- Trial name
- NCT06831942
- Testing
- ASSIP-OA, Treatment as Usual (TAU)
- Where
- 2 sites in Sweden
- Volunteers
- 132 people
- Sponsor
- Vastra Gotaland Region
Non-suicidal Self-injury
Effects of taVNS Combined With tACS on Adolescents With Non-Suicidal Self-Injury
NSSI behavior is highly prevalent among adolescents, and its mechanisms are closely associated with attentional bias toward self-injury-related information and impulsivity, both of which may be related to reduced dlPFC activation…
- Trial name
- NCT07486804
- Testing
- 25Hz、300us transcutaneous auricular vagus nerve stimulation and10hz transcranial alternating current stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Depression, Suicidal Ideation
Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality
The investigators hypothesized that during the 9-week course of Engage \& Connect treatment there will be an increase in brain functions of the Positive Valence System which in turn will lead to reduction in suicidality.
- Conditions
- Depression, Suicidal Ideation, Major Depressive Disorder, Depressive Disorder
- Trial name
- NCT05925322
- Testing
- "Engage & Connect" Psychotherapy, Symptom Review and Psychoeducation (SRP)
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Weill Medical College of Cornell University
Suicidal Thoughts and Behaviors, Social Connectedness
Social Threat, Adolescent Relationships, and Suicidality Study
In recent years, adolescents are having higher rates of emotional health problems, such as suicidal thoughts and behaviors (STBs).
- Conditions
- Suicidal Thoughts and Behaviors, Social Connectedness, Responses to Social Threat
- Trial name
- STARS (NCT07294079)
- Testing
- Social threat
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pittsburgh
Suicidal Ideation, Suicide Attempt
Neural Correlates of Suicidal Behavior in Youth
This study, titled "Neural Correlates of Suicidal Behavior in Youth: a Pre and Post CAMS Therapy Neuroimaging Study," aims to better understand the brain mechanisms underlying suicidal thoughts and behaviors in adolescents and…
- Conditions
- Suicidal Ideation, Suicide Attempt, Suicidal Behavior, Depression / Major Depressive Disorder
- Trial name
- NCT07568054
- Testing
- CAMS
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Depression, Major Depressive Disorder
RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS
In this research study, investigators examine how brain activity changes during tests of emotional processing, attention, and memory using multimodal neuroimaging methods including electroencephalography (EEG), functional…
- Conditions
- Depression, Major Depressive Disorder, Suicidal Ideation
- Trial name
- NCT05977439
- Testing
- Single-Pulse Transcranial Magnetic Stimulation, EEG-Synchronized Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Depression, Alcoholism
Suicidal Behavior in Patients Diagnosed With Bipolar Disorder
The purpose of this study is to learn the environmental and psychological factors that impact suicidality in patients diagnosed with Bipolar Disorder.
- Conditions
- Depression, Alcoholism, Drug Abuse
- Trial name
- NCT02604277
- Testing
- Interpersonal and Social Rhythm Therapy (ISRT), Bipolar-Specific Cognitive Behavioral Therapy (CBT), Mindfulness-Based Stress Reduction (MBSR)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Emory University
Alcohol Use Disorder (AUD), Suicidal Ideation
Examining the Relationship Between Ongoing Alcohol Use, Suicidal Thoughts and Behaviors and Related Constructs, and Behavioral Economic Decision-Making.
This study will evaluate the relationship between alcohol use, suicidal thoughts and behaviors, and behavioral economic decision-making.
- Trial name
- NCT07842588
- Testing
- CBT4CBT
- Volunteers
- 180 people
- Sponsor
- Mark J Rzeszutek, PhD
Major Depressive Disorder
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
The study will consist of a 24-week-long trial examining outcomes in patients with Major Depressive Disorder and suicidal ideation who will receive intravenous (IV) ketamine and intranasal (IN) esketamine, compared to a large…
- Trial name
- NCT05450432
- Testing
- Ketamine, Esketamine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Suicidal Ideation and Behavior
Design and Feasibility of an SMS-based Safety Planning Intervention
This study is testing whether it is feasible to run a larger randomized controlled trial and whether an automated text messaging program is acceptable to young adults who have suicidal thoughts.
- Trial name
- NCT07365579
- Testing
- Text Messaging based Safety Planning Intervention, Facilitated Referral to Crisis Resources
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwestern University
Glioblastoma (GBM)
Mental Health and Suicidality in Glioblastoma Patients in Germany
The aim of the study is to use standardized questionnaires to systematically record influencing factors or predictors for suicidal behavior in glioblastoma patients, particularly with regard to existing depression and anxiety…
- Trial name
- SHINE-GLIO (NCT07409584)
- Testing
- Medical history, physical examination, completing questionnaires, data collection
- Where
- 6 sites in Germany
- Volunteers
- 180 people
- Sponsor
- University Hospital, Essen
Reintegration Difficulties, Suicidal Ideation and Behaviors
Expanding Veteran Sponsorship Initiative+ to Support High-Risk Transitioning Servicemembers and Veterans: A Precision Medicine Approach
Background Young Veterans in the U.S. face a heightened risk of suicide, particularly during the first year after leaving military service-a period often referred to as the "deadly gap." Suicide rates among Veterans aged 18 to 34…
- Conditions
- Reintegration Difficulties, Suicidal Ideation and Behaviors, Health, Connectedness
- Trial name
- NCT07356492
- Testing
- Onward Ops- receive peer sponsor and community support, VA stepped care services
- Where
- United States
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A
This Study will comprehensively evaluate a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartA (NCT06223867)
- Testing
- Jaspr App + JAH, ETAU
- Where
- United States
- Volunteers
- 670 people
- Sponsor
- University of Massachusetts, Worcester
Suicidal Thoughts, Sexual and Gender Minorities
Piloting a Brief, Online Intervention for Suicidality in Sexual and Gender Minority Youth
Sexual and gender minority youth (i.e., LGBTQ+ individuals) are at elevated risk for suicidal thoughts compared to cisgender/heterosexual youth and there is increased demand for programs and treatments tailored to this…
- Conditions
- Suicidal Thoughts, Sexual and Gender Minorities, Youth
- Trial name
- NCT07402265
- Testing
- KindMind
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Western University
Suicide, Mental Health Disorder
A Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death amongst youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be…
- Conditions
- Suicide, Mental Health Disorder, Anhedonia
- Trial name
- ViraSafeRCT (NCT07348666)
- Testing
- ViraSafe: Treatment pushes, BRITE
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Ksana Health