Clinical trials: Sufentanil
Moderate-to-severe Acute Pain
Open-Label Safety and Efficacy of the Sufentanil Sublingual Tablet 30 mcg for Acute Pain
To evaluate the safety and efficacy of sufentanil tablet (ST) 30 mcg in the management of moderate-to-severe acute pain in patients in an emergency room (ER) setting.
- Trial name
- NCT02447848
- Testing
- sufentanil sublingual 30 mcg tablet
- Where
- 3 sites in United States
- Volunteers
- 76 people
- Sponsor
- Talphera, Inc
Cancer, Pain
A Study for the Evaluation of the Safety, Tolerability, and Efficacy of ARX-F02 (Sufentanil NanoTab) Compared to Placebo in the Treatment of Cancer Breakthrough Pain
The purpose of this research study was to evaluate ARX-F02 (Sufentanil NanoTab) versus placebo ("sugar" pill or inactive substance) in the management of breakthrough pain in cancer patients.
- Trial name
- NCT00833040
- Where
- 13 sites in United States
- Volunteers
- 34 people
- Sponsor
- Talphera, Inc
Patient-controlled Analgesia
The Comparison of the Analgesic Effects of Dezocine and Sufentanil in Patient-controlled Analgesia After Laryngectomy
Laryngeal cancer is one of the most common tumors in otolaryngology. In China, it accounts for 1-5% of all malignancies and has an incidence of 1.13 per 100,000.
- Trial name
- NCT06000137
- Testing
- Dezocine, Sufentanil injection, Flurbiprofen
- Where
- China
- Volunteers
- 129 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Pain
Improving Pain Management and Decreasing LOS After Total Hip Arthroplasty (THA) and Total Knee Arthroplasty (TKA)
This two arm, patient blinded, randomized, post market clinical trial in a single orthopedic hospital will determine whether there is improved pain management and decreased length of stay when comparing standard of care pain…
- Trial name
- NCT05307341
- Testing
- sufentanil
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- More Foundation
Postoperative Nausea and Vomiting (PONV), Enhanced Recovery After Surgery
Efficacy and Safety Between Tegileridine and Sufentanil in Laparoscopic Surgery Patients at High Risk of Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) is one of the most common and distressing perioperative adverse events in patients undergoing laparoscopic surgery.1 Although laparoscopic procedures are minimally invasive, PONV can still…
- Conditions
- Postoperative Nausea and Vomiting (PONV), Enhanced Recovery After Surgery, Laparoscopic Surgery
- Trial name
- NCT07691086
- Testing
- analgesic drugs and methods
- Volunteers
- 800 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Thoracic Surgery, Video-assisted, Postoperative Pain
RCT Comparing Analgesia Post-VATS With Epimorph VS Placebo
The purpose of the study is to determine if the administration of a mix of Sufentanil and Morphine in intrathecal is a better analgesia regimen than PCA alone in patient post-VATS.
- Conditions
- Thoracic Surgery, Video-assisted, Postoperative Pain, Rachianesthesia, Sufentanil
- Trial name
- NCT02152514
- Testing
- Intrathecal Morphine/Sufentanil, PCA
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Université de Sherbrooke
Nociceptive Pain
Guiding Sufentanil Administration With Skin Conductance in Mechanically Ventilated Intensive Care Patients
Opioid administration in mechanically ventilated patients in the intensive care unit (ICU) is essential to maintaining patient respiratory and hemodynamic stability.
- Trial name
- NCT04696016
- Testing
- Skin conductance guided antinociception, Standard care antinociception
- Volunteers
- 30 people
- Sponsor
- Erasme University Hospital
Intraoperative Hypotension
Effects of Sufentanil on the Intraoperative Hemodynamics
This study is a randomized, controlled trial. A total of 92 patients will be randomized to receive sufentanil or remifentanil during extracranial-intracranial bypass surgery.
- Trial name
- NCT06091904
- Testing
- Sufentanil, Remifentanil
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Pain, Postoperative, Pain
Monitor-Guided Analgesia During General Anesthesia - Part II
This prospective randomized clinical trial evaluates the effects of a monitor-guided opioid analgesia during general anesthesia.
- Conditions
- Pain, Postoperative, Pain, Nociceptive Pain, Opioid Use
- Trial name
- MOGADA-II (NCT03380949)
- Testing
- Opioid administration (remifentanil) in intervention group, Opioid administration (remifentanil) in control group
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Patients Undergoing Cardiac Surgery, Patients With Coronary Artery Bypass Surgery With CEC
Ability of Pupillometry to Reduce Sufentanil Consumption in Planned Cardiac Surgery: Randomized, Controlled, Single-center Clinical Superiority Trial
The objective of general anesthesia is to obtain a loss of consciousness, stillness, and sufficient analgesia to allow surgery. Thus, general anesthesia has two components: hypnosis and analgesia.
- Trial name
- PUCCAR (NCT03864016)
- Testing
- Induction and maintenance of anesthesia, Adaptation of sufentanil doses according to the usual protocol, Adjustment of sufentanil doses according to pupillometry
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Myocardial Injury
Sufentanil in Patients With Lower Extremity Fracture Surgery Myocardial Damage Function Study
1. To analyze the association of different doses of opioids on myocardial injury/protection through BMP-6/SMAD pathway. 2. To observe the effect of different doses of opioids on the expression of BMP-6 in bone marrow. 3.
- Trial name
- Sipwlefsmdfs (NCT06808841)
- Testing
- Sufentanil injection
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Second Hospital of Shanxi Medical University
Emergencies, Pain, Acute
Sufentanil Intranasal
Study of the effects of intranasal sufentanil on patients presenting to the emergency department with acute post-traumatic pain.
- Conditions
- Emergencies, Pain, Acute, Analgesia, Sufentanil
- Trial name
- NCT04137198
- Testing
- Sufentanil
- Where
- Belgium
- Volunteers
- 170 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Laparoscopic Cholecystectomy, Analgesics，Opioid
ED50 of Sufentanil for Intraoperative Analgesia
1. Sufentanil as an strong analgesic is used widespreadly during laparoscopic cholecystectomy. 2. Lower dosages of sufentanil facilitated with dexmedetomidine can offer enough analgesia effect. 3.
- Trial name
- ED50 (NCT06662656)
- Where
- China
- Volunteers
- 26 people
- Sponsor
- China International Neuroscience Institution
Cough
90% Effective Infusion Time of Sufentanil to Prevent Induction Cough: A Biased Coin Sequential Study
This single-center, prospective biased coin up-and-down sequential study aims to determine the 90% effective infusion time (ET90) of sufentanil to prevent sufentanil-induced cough (SIC) during the induction phase of general…
- Trial name
- NCT07778953
- Testing
- Sufentanil Citrate
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shiyou Wei
Anesthesia Brain Monitor, Sufentanil
Effects of Sufentanil Target Controlled Infusion on Patient State Index Values and Electroencephalographic Spectrum During Total Intravenous Anesthesia With Propofol
Sufentanil Target Controlled infusion (TCI, Gepts model) effects on Neuromonitoring during Total Intravenous Anesthesia (TIVA) with Propofol TCI (Eleveld model) has not been investigate yet.
- Conditions
- Anesthesia Brain Monitor, Sufentanil, Target Controlled Infusion
- Trial name
- NCT06388408
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Padova
Patients Undergoing Laparoscopic Nephrectomy
Study on Efficacy of iv PCA With Fentanyl or Sufentanil in Patients Undergoing Laparoscopic Nephrectomy
The purpose of this study is to compare the efficacy of iv PCA with fentanyl or sufentanil in patients undergoing laparoscopic nephrectomy
- Trial name
- NCT03171610
- Testing
- Sufentanil group, Fentanyl group
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Yonsei University
Major Abdominal Surgery
Individualized Goal-directed Sufentanil Administration Versus Standard Therapy in Patients Undergoing Major Abdominal Surgery
To determine whether a treatment strategy targeting an individualized sufentanil administration based on the Analgesia Nociception Index (ANI) could reduce the total dose of sufentanil during major abdominal surgery, as compared…
- Trial name
- PHOENIX (NCT03166644)
- Testing
- Analgesia Nociception Index (ANI)-guided sufentanil administration
- Where
- France
- Volunteers
- 128 people
- Sponsor
- University Hospital, Clermont-Ferrand
Post-Operative Pain
A Multicenter, Randomized, Open-Label, Parallel-Group Trial to Compare the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™)to Intravenous Patient-Controlled Analgesia With Morphine for the Treatment of Acute Post-Operative Pain
The study is intended to show that the Sufentanil NanoTab PCA System is as effective as morphine intravenous patient-controlled analgesia (IV PCA) for treating pain after surgery.
- Trial name
- NCT01539538
- Testing
- Sufentanil NanoTab PCA System/15 mcg, morphine IV PCA
- Where
- 16 sites in United States
- Volunteers
- 357 people
- Sponsor
- Talphera, Inc
Post Operative Pain Management
Different Lipid Soluble Opioids for Gynecologic Laparoscopic Surgery Postoperative Patient-controlled Analgesia
The investigators noticed that Body Fat Ratio might have great influence on the efficacy of different lipid soluble anesthetics.
- Trial name
- NCT01917045
- Testing
- Sufentanil (R30730, brand name Sufenta), Sufentanil (R30730, brand name Sufenta) + Morphine, Morphine
- Volunteers
- 180 people
- Sponsor
- Peking University First Hospital
Arteriovenous Malformation
Effect of Dexmedetomidine Combined With Sufentanil for Postoperative Intravenous Analgesia in Neurosurgery
The purpose of this study is to determine effect of combined medication of sufentanil and dexmedetomidine in patient controlled analgesia after neurosurgery.
- Trial name
- NCT02552459
- Testing
- Sufentanil, dexmedetomidine 1, dexmedetomidine 2
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University