Clinical trials: Substance Use Disorder (SUD)
Substance Use Disorder (SUD)
Mobile Phone-based Smoking Cessation Program
In this online, randomized controlled trial (RCT), the participants will be randomized and allocated in 1:1 ratio to mobile phone-based intervention group or to the wait-list control group.
- Trial name
- NCT06747182
- Testing
- mobile phone-based intervention
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Substance Use Disorder (SUD)
Research and Engagement on Substance Use: Harnessing Awareness and Personalized Education (RESHAPE) to Improve Well-being and Self-efficacy
The goal of the RESHAPE study is to learn about the needs and experiences of adults who report having, or being at risk for, substance use disorder.
- Trial name
- RESHAPE (NCT06952491)
- Where
- United States
- Volunteers
- 1,910 people
- Sponsor
- Evidation Health
Substance Use Disorders, Insomnia
Feasibility of Brief Behavioral Therapy for Insomnia (BBTI) in SUD Recovery
The goal of this clinical study is to learn whether treating sleep problems is helpful in people with substance abuse problems who are living in a residential treatment program.
- Trial name
- BBTI_SUDs (NCT05935735)
- Testing
- Brief Behavioral Therapy for Insomnia (BBTI)
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Attention Deficit Hyperactivity Disorder
Atomoxetine/Attention Deficit/ Hyperactive Disorder (ADHD)/Substance Use Disorder (SUD)in a Residential Treatment Facility
Although Attention Deficit/ Hyperactive Disorder (ADHD) is a common comorbidity in individuals diagnosed with Substance Use Disorder (SUD), little data currently exists on the utility of screening tools in large samples of adult…
- Trial name
- NCT00953862
- Testing
- Atomoxetine
- Volunteers
- 18 people
- Sponsor
- NYU Langone Health
Tiletamine Use Disorder, Substance Use Disorder (SUD)
The Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation in Individuals With Tiletamine Use Disorder
Participants diagnosed with tiletamine use disorder will be assigned to active or sham taVNS for 5 days. Clinical outcomes ( e.g., behavioral paradigms measures and clinical scales ) and physiological markers (e.g., EEG and ECG)…
- Conditions
- Tiletamine Use Disorder, Substance Use Disorder (SUD), Drug Craving
- Trial name
- taVNS-Tiletami (NCT07689981)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Mental Health Center
Substance Use Disorder (SUD)
Study to Confirm the AuthenTicity of Point of Care Urine samplEs Using Oral fluoreScein Sodium in adulTs With substancE Use Disorder (ATTESTED)
The purpose of this phase III, randomized, double-blind, placebo-controlled study is to confirm the authenticity of point-of-care urine samples in adult persons with substance use disorder using fluorescein sodium as a marker.
- Trial name
- ATTESTED (NCT07356349)
- Testing
- Fluorescein
- Volunteers
- 114 people
- Sponsor
- UpTru Inc.
Substance Use Disorder (SUD), Decayed Teeth
Oral and Dental Health in Substance Dependent Individuals
The goal of this cross-sectional clinical study is to compare the oral health status of individuals with Methamphetamine (MA), Cannabis (THC), and Polysubstance (PSU) use disorders to healthy controls.
- Conditions
- Substance Use Disorder (SUD), Decayed Teeth, Teeth Loss, Teeth Missing
- Trial name
- ODH_SUD (NCT06640712)
- Testing
- Dental caries was assessed using the DMFT index (Decayed, Missing, and Filled Teeth) according to the World Health Organization's caries diagnostic criteria., Substance Use Disorder Diagnosis
- Where
- Turkey (Türkiye)
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Substance Use Disorder (SUD), Recovery
Using Smartphones to Provide Recovery Support Services
The primary goal of the proposed trial is to examine the effect of combining frequent self-monitoring via Ecological Momentary Assessment (EMAs) and automated interventions via Ecological Momentary Interventions (EMIs) provided…
- Trial name
- SRSS (NCT02132481)
- Testing
- EMA Only, EMI Only, EMA+EMI
- Where
- 3 sites in United States
- Volunteers
- 401 people
- Sponsor
- Chestnut Health Systems
Substance Use Disorder (SUD), Alcohol Use Disorder (AUD)
Metabolome and Gut Microbiome Changes During Smoking Cessation in Long-term Drug Therapy in a Therapeutic Community
Theoretical Framework: Cigarette smoking is the leading preventable cause of death worldwide, with nicotine dependence notably common among individuals with Substance Use Disorders (SUD).
- Conditions
- Substance Use Disorder (SUD), Alcohol Use Disorder (AUD), Nicotine Addiction, Healthy Adult Participants
- Trial name
- NCT06803706
- Testing
- 6-weeks CBT smoking cessation programme, Long-term drug therapy within a therapeutic community
- Where
- 3 sites in Austria
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Sigmund Freud PrivatUniversitat
Substance Use Disorders
The Longitudinal Impact of SES and the CNDS on Recovery From SUD
The goal of this study is to provide a scientific understanding of the impact of socioeconomic status (SES) on the recovery trajectory (psychosocial functioning, relapse/remission status, and neurocognitive mechanisms).
- Trial name
- NCT05103514
- Testing
- Online Survey
- Sponsor
- Virginia Polytechnic Institute and State University
Substance Use Disorders
From Addiction to Employment.
Patients with substance use disorders have low employment rates and are to a large extent on the outside of the ordinary labor market.
- Trial name
- IPS-SUD (NCT04289415)
- Testing
- Individual Placement and Support
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Health Disparity, Minority and Vulnerable Populations
Pilot Test of a Mobile App That Helps Spanish-speakers Find Mental Health Services in the US.
The goal of this observational study is to develop and test a mobile app for Spanish speakers residing in the US who seeking drug treatment and/or behavioral health services for themselves or an associate.
- Trial name
- NCT06619431
- Testing
- Mobile Application
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Volver Health
Prisoners, Substance Use History
Calls and Coordination for Transitions of Care at Re-entry
The goal of this clinical trial is to learn if a short program for people being released from prison can help connect them to medical care.
- Conditions
- Prisoners, Substance Use History, Chronic Medical Conditions, Psychiatric Condition
- Trial name
- Call2Care (NCT06794983)
- Testing
- In-person visit with study team member, In-person visit with NCM, Phone calls and texts
- Where
- United States
- Volunteers
- 488 people
- Sponsor
- University of Wisconsin, Madison
Substance Use Disorder (SUD)
Contextualization and Digitalization of WHO's Mental Health Action Gap Intervention Guide Substance Use Disorders Module
The aim of study is to: 1. To contextualize, adapt, customize and digitalize WHO's Mental Health Gap Action Programme Intervention Guide (e-mhGAP-IG); Substance Use Disorders Module (SUD module) V 2.0 for primary care settings…
- Trial name
- NCT07386574
- Testing
- mhGap IG SUD Module Intervention Training, Control
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Living and Learning
Substance Use Disorder (SUD), HIV
ENTRUST - Economic Navigation and Strengthening to Realize Unrestricted Services for Transgender Women
Transgender women in Florida are economically disadvantaged and at highest risk for substance use disorders, HIV transmission and/or non-adherence to antiretroviral treatment, yet remain underrepresented in research.
- Trial name
- ENTRUST (NCT06667713)
- Testing
- ENTRUST - substance use and HIV counseling and goal setting with economic empowerment and photovoice training, SBIRT-T only
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Central Florida
Opioid Use Disorder, Maternal Drugs Affecting Fetus
Night Respite for Postpartum Mothers With SUD
This single arm pilot feasibility study will evaluate the implementation of overnight infant respite care and parenting skills to mothers with substance use disorders in the early postpartum period residing in residential…
- Conditions
- Opioid Use Disorder, Maternal Drugs Affecting Fetus, Postpartum Mood Disturbance, Sleep Disorder
- Trial name
- NCT05746507
- Testing
- Night Respite Care
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Massachusetts General Hospital
Substance Use Disorder (SUD), Pregnancy
Substance Use in Pregnancy - Optimizing Retention in Treatment
Substance use during pregnancy is a leading cause of maternal morbidity and mortality in the United States, with 55-80% of postpartum patients disengaging from substance use disorder (SUD) treatment within one year of delivery.
- Conditions
- Substance Use Disorder (SUD), Pregnancy, Postpartum, Contingency Management
- Trial name
- SUPPORT-MOM (NCT07104123)
- Testing
- Social drivers of health screening, Patients will undergo a program of contingency management
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Washington University School of Medicine
Substance Use Disorders, Substance Abuse
Senyo Health With Substance Use Disorder (SUD) in Primary Care
The purpose of this study is to examine the barriers, facilitators, and optimal processes for implementing a digitally enhanced screening, brief intervention, and referral to treatment (SBIRT) model for Substance Use Disorder SUD…
- Trial name
- NCT06743282
- Testing
- Senyo App, Follow-up
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Post Traumatic Stress Disorder, Substance Use Disorders
Virtual Mantram Program for Patients With PTSD and SUD
The purpose of this study is to evaluate a virtual Mantram repetition program for adults with PTSD and substance use disorders. The program involves repetition of a personalized Mantram, which is a word or short phrase with…
- Trial name
- NCT05058963
- Testing
- Mantram repetition program
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- Centre for Addiction and Mental Health
Substance Use Disorders, Opioid Use Disorder
Substance Use and Lifestyle-related Health Problems in Ageing Patients in OMT Treatment
The overall aim of the study is to explore substance use, tobacco use and lifestyle-related health problems among ageing patients in Opioid Maintenance Treatment (OMT), and other SUD treatment.
- Conditions
- Substance Use Disorders, Opioid Use Disorder, Tobacco Use, Health, Subjective
- Trial name
- AgeSUD (NCT05182918)
- Testing
- Substance use disorder treatment
- Where
- Norway
- Volunteers
- 548 people
- Sponsor
- Sorlandet Hospital HF