Clinical trials: Substance Use
HIV Infections
Using Mobile Technology to Prevent HIV and Related Youth Health Problems
Since the start of this study I have moved from NYSPI to City University of New York. The study is currently paused. The goal of the project is to find out how the investigators can use mobile phones to prevent HIV and address…
- Trial name
- YouthHealth (NCT05130151)
- Testing
- Youth Health SMS
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Sleep Disturbance, Sleep Problems
Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents
This cluster randomized controlled trial will evaluate whether a brief, school-based group adaptation of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) improves sleep and mental health in…
- Conditions
- Sleep Disturbance, Sleep Problems, Substance Use (Drugs, Alcohol), Anxiety
- Trial name
- SLEEP-TEEN (NCT07865728)
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction, Healthy habits psychoeducation
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Alcohol Use Disorder, Alcohol-associated Liver Disease
Pomegranate Dietary Supplements in AUD and ALD
The goal of this project is to determine an individual's ability to generate active gut microbial metabolites called urolithins upon consumption of pomegranate dietary supplements.
- Conditions
- Alcohol Use Disorder, Alcohol-associated Liver Disease, Alcoholic Cirrhosis, Healthy
- Trial name
- NCT07678567
- Testing
- Pomegranate Dietary Ssupplement
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Substance Use, Healthy Subjects
Abuse Potential and Human Pharmacology of Methylone
The purposes of the study are 1) To assess the abuse potential of methylone after controlled administration of a single oral dose of methylone 2) to evaluate subjective and physiological effects of methylone 3) to determine the…
- Trial name
- METI/FIS/1 (NCT05488171)
- Testing
- Methylone, 3,4-methylenedioxymethamphetamine
- Where
- Spain
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Germans Trias i Pujol Hospital
Cigarette Smoking, Nicotine Dependence
Reducing Tobacco Use Disparities Among Low-Income Adults
Most smokers, especially those who are poor, do not receive smoking cessation treatment during their healthcare visits. This study is evaluating a novel population health management intervention for low-income smokers.
- Trial name
- NCT03077737
- Testing
- Choose to Change, Enhanced usual care
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Sexual Risk, Substance Use
An Innovative HIV Prevention Intervention Using Social Networking Technology
An existing face-to-face HIV prevention intervention (The Young Men's Health Project, YMHP; R01DA20366) will be iteratively adapted and pilot-tested to target difficult to engage high-risk young men who have sex with men (YMSM)…
- Trial name
- NCT01381653
- Testing
- Behavioral: HIV prevention intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
Depression Disorders, Affective Disorders
Prevention of Mental Disorders Through Self-efficacy Interventions
Low self-efficacy is a transdiagnostic risk factor for several mental disorders. Self-efficacy refers to one's belief that one is capable of performing a behavior necessary to successfully complete a task or achieve a goal.
- Conditions
- Depression Disorders, Affective Disorders, Prevention, Substance Use Disorders
- Trial name
- SELFTIE (NCT06738953)
- Testing
- Cognitive-Behavioral Intervention to increase Self Efficacy
- Where
- Germany
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Health and Medical University Potsdam
Substance Abuse Problem, Pregnancy
Prenatal Cocaine, Nasal Oxytocin, and Maternal Psychophysiology
The purpose of this research is to study the effects of nasal oxytocin administration on maternal behaviors that may be influenced by cocaine use during pregnancy.
- Trial name
- NOX (NCT02872467)
- Testing
- Syntocinon treatment
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infections, Substance Use
Women Focused Encounters for Resilience Independence Strength and Eudaimonia
The goal of this combination Type 1 hybrid and observational study is to evaluate the impact of a peer delivered intervention of acceptance and commitment therapy (ACT) + exercise + social support to address the substance…
- Conditions
- HIV Infections, Substance Use, Trauma, Medication Adherence
- Trial name
- WE RISE (NCT06216600)
- Testing
- Acceptance and Commitment Therapy (ACT), Body weight circuit training, Empathetic social support
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Tobacco Use Disorder
Combining a Smoke Ending Aid With Behavioral Treatment - 1
The purpose of this study is to combine a smoke ending aid with behavioral treatment.
- Trial name
- NCT00006151
- Testing
- Behavioral Therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peter Gariti
PTSD, Substance Use Disorders
COPEWeb Training for Providers
Post-traumatic stress disorder (PTSD) and substance use disorders (SUD) are two of the most common and debilitating mental health conditions afflicting military Veterans.
- Trial name
- COPEWeb (NCT05812131)
- Testing
- COPEWeb online training, COPE In Person
- Where
- United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depression, Tobacco Use Disorder
A Behavioral Activation Prenatal and Postpartum Intervention for Depressed Pregnant Smokers
This study evaluates a mood management and health and wellness smoking cessation intervention for depressed pregnant smokers during and after birth.
- Trial name
- NCT05044546
- Testing
- Behavioral Activation Therapy, Discussion, Health Education
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Behavioral Health
Testing the Effectiveness and Implementation of a Meditation App for Youth in the Legal System
The goals of this hybrid type 2 randomized controlled trial (RCT) are to evaluate the effectiveness and individual-level implementation of a 1-month app-based meditation program with youth on probation in Cook County, IL.
- Trial name
- NCT06997120
- Testing
- Bodhi AIM (intervention group), HIB (control group)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Tobacco Use Disorder
Examining the Effectiveness of the Nicotine Patch in Male and Female Smokers - 2
Treatment studies have demonstrated that current smoking cessation techniques are less effective for women. The purpose of this study is to determine the role that gender plays on the effectiveness of nicotine replacement…
- Trial name
- NCT00135746
- Testing
- nicotine transdermal system
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking
Cue Reactivity in Virtual Reality: The Role of Context
The objectives of this proposal are to examine the role of context in a virtual reality (VR) environment and to explore the extent to which cues (i.e., contextual cues or explicit smoking cues) influence craving and physiological…
- Trial name
- NCT00862927
- Testing
- Breath Sample, Saliva Sample, Questionnaire
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Adolescent Development
Monetary Incentive Delay Task for Probing Reward-related Neural Processes
150 males and 150 females ages 14-17 years-old will be enrolled in an observational, longitudinal study. There are three planned in-person visits: a baseline assessment, an 18-month follow-up, and a 36-month follow-up.
- Trial name
- MID (NCT06369623)
- Testing
- Monetary Incentive Delay Task
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Substance Abuse
Parent-Adolescent Interactions and Adolescent Development
The purpose of this study is to observe parent-adolescent interactions and to examine the parenting behaviors and adolescent emotional and physiological responses that are associated with youth's substance use.
- Trial name
- PAIT (NCT01572441)
- Where
- 2 sites in United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- George Mason University
Adolescent Drinking, HIV/AIDS
Assessing the Feasibility of Economic Approaches to Prevent Substance Abuse Among Adolescents
The proposed study will test the impact of an economic empowerment intervention on reducing alcohol and drug use (ADU) among adolescents and youth living with HIV (AYLHIV) in poverty-impacted communities in Uganda.
- Conditions
- Adolescent Drinking, HIV/AIDS, Drug Use
- Trial name
- NCT05597865
- Testing
- Economic Empowerment Intervention, Alcohol and Drug Use Risk Reduction Sessions
- Where
- Uganda
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Assault by Handgun Discharge, Violence
Lithium Water in Gun Violence Prevention
The word lithium frequently conjures images of catatonic psychiatric patients and side effects so severe that premature death is commonplace. But naturally occurring lithium is a far cry from pharmaceutical grades.
- Conditions
- Assault by Handgun Discharge, Violence, Homicide, Sexual Assault by Bodily Force
- Trial name
- LWGVP (NCT02213614)
- Testing
- Lithium Water, natural spring water
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- American Society Of Thermalism And Climatology Inc
Tobacco Use Disorder
Tobacco Pilot Study for Low Income Smokers
Pilot study to test feasibility of delivering a motivational smoking cessation intervention to low income smokers via a computer tablet.
- Trial name
- NCT03017092
- Testing
- Tablet-guided tobacco intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
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